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时间:2020-04-17
《HDL-C与冠心病不同程度相关性.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、·64·临床误诊误治2014年6月第27卷第6期ClinicalMisdiagnosis&Mistherapy,Vo1.27,No.6,Jun2014临床研究TC/HDL.C、LDL—C/HDL—C、TG/HDL—C与冠心病不同程度相关性吴燕丹[摘要】目的探讨冠心病患者血清总胆固醇(TC)/高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL—C)/HDL—C、甘油三酯(TG)/HDL—C比值对病情严重程度的预测价值。方法选择明确诊断为冠心病并放置冠状动脉(冠脉)支架的175例作为冠心病组,选择同期无心血管疾病的健康体检者146例作为对照组。冠心病组及对照组均测定血脂
2、7项,即TC、TG、LDL—C、HDL—C及TC/HDL—C、LDL—C/HDL—C、TG/HDL—C比值,分析两组血脂差异及冠脉不同病变程度(3支、2支、1支病变)与血脂变化的相关性。结果冠心病组血脂7项指标均显著高于对照组(P<0.O1);冠心病不同病变支数间TC/HDL—C、TG/HDL—C比较,3支病变显著高于2支和1支病变者(P<0.05);TC/HDL·C、LDL—G/HDL-C比较,3支、2支病变者均高于1支病变者(P<0.05);HDL—C比较,3支病变者低于1支病变者(P<0.05)。结论冠心病患者的血脂比值与冠脉病变的支数密切相关,可作为预测冠心病病情的常
3、规指标。[关键词]冠心病;胆固醇;甘油三酯类;胆固醇,低密度脂蛋白;胆固醇,高密度脂蛋白;疾病严重程度[中国图书资料分类号]R541.4[文献标志码]A[文章编号]1002—3429(2014)06-0064—04『DOI]10.3969/j.issn.1002-3429.2014.06.027CorrelationbetweenRatiosofTC/HDL·C.LDL-C/HDL-CandTG/HDL-CwiththeSeverityofCoronaryHeartDiseaseWUYan—dan(DepartmentofClinicalLaboratory,ShunyiDi
4、strictHospitalofBeijing,Beijing101300,China)[Abstract]ObjectiveToexplorepredictivevaluesofratiosofTC/HDL—C,LDL—C/HDL—CandTG/HDL—Cofpa—tientswithcoronaryheartdisease(CHD)forconditionseverity.MethodsAtotalof175CHDpatientsundergoingcoronaryarterystentplacementwererecruitedasCHDgroup,and146heat
5、lhypersonstakingphysicalexaminationwithoutcardiovascu—lardiseasewerechosenascontrolgroup.Sevenpartsofbloodlipidsindexes[totalcholesterol(TC),triglyceride(TG),lowdensitylipoproteincholesterol(LDL—C),highdensitylipoproteincholesferol(HDL-C),ratiosofTC/HDL—C,LDL—C/HDL—CandTG/HDL—C]weredetected
6、inthetwogroups.Thedifferencesoftheindexesinthetwogroupsandvaluechangesofbloodlipidsindifferentlesions(3lesions,2lesionsand1lesion)wereanalyzed,andthecorrelationsbetweentheindexesandchangesindifferentlesionswerealsoanalyzed.ResultsThesevenindexesinCHDgroupweresignificantlyhigherthanthoseinco
7、ntrolgroup(P<0.01);ratiosofTC/HDL—CandTG/HDL—Cinpatientswith3lesionsweresignificantlyhigherthanthoseinpatientswith2lesionsor1lesion(P<0.05);ratiosofTC/HDL-CandLDL—C/HDL—Cinpatientswith3or2lesionsweresignificantlyhigherthanthoseinpatientswith1lesion(P<0.0
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