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时间:2017-12-07
《超声清创对慢性难愈性创面细菌清除及愈合的影响》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、广州医药2014年第45卷第1期·5·超声清创对慢性难愈性创面细菌清除及愈合的影响刘思容荣新洲樊桂成张涛李庆辉广州医科大学附属广州市第一人民医院烧伤科(510180)【摘要】目的观察多功能超声清创术对慢性难愈性创面细菌清除率及愈合的影响。方法筛选60例患者,随机分为治疗组与对照组,治疗组予超声清创后用碘伏消毒包扎;对照组用生理盐水清创后用碘伏消毒包扎;第一次清创前后各留取细菌标本。结果治疗组细菌清除率为90.48%,对照组为66.67%,两组差异有统计学意义(P2、统计学意义(P<0.01),治疗组创面愈合率优于对照组。结论多功能超声清创仪可明显减轻创面“细菌负荷”,减少炎症反应,从而达到明显促进创面愈合的效果。【关键词】超声清创慢性创面细菌清创率愈合DOI:10.3969/j.issn.1000—8535.2014.O1.002EfectofultrasounddebridementonbacteriacleaningandtherapeuticefectinchronicwoundsLiuSirong,RongXinzhou,FanGuicheng,eta1.GuangzhoufimtPeople'sh3、ospital,GuangzhouMedicalUniversity,Guangzhou510180,China【Abstract】ObjectiveToobservetheeffectofmulti—functionalultrasonicdebridementinstrumentonbacteriacleaningandtherapeuticeffectinchronicwounds.Methods60patientswereselectedwithchronicwoundswererandomlydividedintotwogroups,n4、amelyexperimentalgroupandcontrolgroup,experimentalgroupwithpovidone—iodinedisinfectionbandageafterthoroughdebridementdisinfectedwithimprovedultrasonicdebridementinstrument;controlgroupdisinfectedwithpovidone—iodinedressingsafterflushedwithsaline;Wecollectedbacterialspecimensb5、eforeandafterthefirstdebridement.Detectingbacteriacontentbeforeandafterwounddebridement,andobservedwoundhealingeffects.ResultsTheaveragebacterialclearancerateoftheexperimentalgroupis90.48%,controlgroupis66.67%,thedifferencewasstatisticallysignificant(P<0.01);thechronicwoundre6、ductionrateof’experimentalgroupis45.83%,andthecontrolgroupis19.89%,thedifferencewasstatistical·lysignificant(P<0.01),andtheperipheralinflammationofdebridementgroupwassignificantlydecreasedthanthecontrolgroup.ConclusionMulti-ultrasonicdebridementinstrumentcouldalleviate“bacter7、ialload”,quicklyreduceinflammation,obviouslypromotewoundhealing.【Keywords】Ultrasounddebridement;Chronicwounds;Bacterialcleaning;healing慢性难愈性创面如糖尿病足、压力性溃疡、脉管性溃肉芽创面6例。无严重的心脑血管疾病,无恶性肿瘤病史。疡及外伤性溃疡等超过8周⋯,创面常合并严重感染,随机分为治疗组及对照组各30例,治疗组用CareMaster系较多细菌菌落繁殖,形成多聚糖一蛋白质复合物的生物膜,列超声清创仪(深圳普门8、科技有限公司)清创治疗,对照成为细菌的保护层卜,细菌、生物膜及坏死物的堆积造组用传统生理盐水冲洗清创。两组患者一般情况如年龄、成创面床的
2、统计学意义(P<0.01),治疗组创面愈合率优于对照组。结论多功能超声清创仪可明显减轻创面“细菌负荷”,减少炎症反应,从而达到明显促进创面愈合的效果。【关键词】超声清创慢性创面细菌清创率愈合DOI:10.3969/j.issn.1000—8535.2014.O1.002EfectofultrasounddebridementonbacteriacleaningandtherapeuticefectinchronicwoundsLiuSirong,RongXinzhou,FanGuicheng,eta1.GuangzhoufimtPeople'sh
3、ospital,GuangzhouMedicalUniversity,Guangzhou510180,China【Abstract】ObjectiveToobservetheeffectofmulti—functionalultrasonicdebridementinstrumentonbacteriacleaningandtherapeuticeffectinchronicwounds.Methods60patientswereselectedwithchronicwoundswererandomlydividedintotwogroups,n
4、amelyexperimentalgroupandcontrolgroup,experimentalgroupwithpovidone—iodinedisinfectionbandageafterthoroughdebridementdisinfectedwithimprovedultrasonicdebridementinstrument;controlgroupdisinfectedwithpovidone—iodinedressingsafterflushedwithsaline;Wecollectedbacterialspecimensb
5、eforeandafterthefirstdebridement.Detectingbacteriacontentbeforeandafterwounddebridement,andobservedwoundhealingeffects.ResultsTheaveragebacterialclearancerateoftheexperimentalgroupis90.48%,controlgroupis66.67%,thedifferencewasstatisticallysignificant(P<0.01);thechronicwoundre
6、ductionrateof’experimentalgroupis45.83%,andthecontrolgroupis19.89%,thedifferencewasstatistical·lysignificant(P<0.01),andtheperipheralinflammationofdebridementgroupwassignificantlydecreasedthanthecontrolgroup.ConclusionMulti-ultrasonicdebridementinstrumentcouldalleviate“bacter
7、ialload”,quicklyreduceinflammation,obviouslypromotewoundhealing.【Keywords】Ultrasounddebridement;Chronicwounds;Bacterialcleaning;healing慢性难愈性创面如糖尿病足、压力性溃疡、脉管性溃肉芽创面6例。无严重的心脑血管疾病,无恶性肿瘤病史。疡及外伤性溃疡等超过8周⋯,创面常合并严重感染,随机分为治疗组及对照组各30例,治疗组用CareMaster系较多细菌菌落繁殖,形成多聚糖一蛋白质复合物的生物膜,列超声清创仪(深圳普门
8、科技有限公司)清创治疗,对照成为细菌的保护层卜,细菌、生物膜及坏死物的堆积造组用传统生理盐水冲洗清创。两组患者一般情况如年龄、成创面床的
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