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时间:2020-04-14
《年轻人原发性闭角型青光眼的临床特征-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、中华眼视光学与视觉科学杂志2011年8月第13卷第4期ChinJVisSci,August2011,Vo1.13,No.4255·青光眼·年轻人原发性闭角型青光眼的临床特征孙红袁志兰虞灵梅胡春玲【摘要】目的探讨年轻人原发性闭角型青光眼(PACG)的临床特征。方法回顾性病例对照研究。收集2006年1月至2010年7月期间南京医科大学第一附属医院眼科收治的年龄<40岁、临床确诊为PACG的患者12例(22眼),及同期单纯行小梁切除术的老年PACG患者217例(236眼)。对两组病例的临床表现、房角结构特点、手术效果以及术后浅前房和恶性青光眼的发生率进行比较
2、。采用配对t检验和xz检验对数据进行统计学分析。结果年轻PACG患者平均年龄为(32.8+5.7)岁,女性占75%.首次就诊时均已为中晚期,无急性发作症状,眼轴平均为(21.1+1.9)mm,11例(20眼)为高褶虹膜构型(占91%),仅1例(2眼)为瞳孔阻滞。随访时间平均为(24.8~6.3)个月,最后一次复诊时眼压较术前下降fl1.6~5.2)mmHg,手术前后差异有统计学意义O=6.456,P<0.01)。术后并发症主要有浅前房(44%),恶性青光眼f17%)。老年PACG患者平均年龄为(60.2~7.1)岁,女性占81%,眼轴平均为(21.5~
3、2.7)mm,高褶虹膜构型仅占19%,瞳孑L阻滞占81%,其房角构型与年轻PACG患者相比差异有统计学意义(XZ=-56.446、14.303.P4、ngerpatientsSUNHong.YUANZhi—lan,YULing—mei*,HUChun-ling.DepartmentofOphthalmology,theFirstAffiliatedHospitalofNanjingMedicalUniversity,Nanjing210029,ChinaCorrespondingauthor:YUANZhi-lan,Email:zhilanyuan@vip.sincacom【Abstract】ObjecfiveToevaluatetheclinicalcharacteristicsofyounger5、patientswithprimaryangle—closureglaucoma(PACG).MethodsRetrospectivecasecontrolstudy.Twelvepatients(22eyes)aged40oryoungerwithaconfirmeddiagnosisofPACGfromJanuary2006toJuly2010wereinvestigated.Atthetimeoftheinitialdiagnosis.aUpatientswereinthemiddleorlatestageanddidnotfeelsignifi6、cantpain.Eighteeneyesunderwentsurgicaltreatment.Fullophthalmicexaminationswereperformed.Theywerecomparedto217olderpatients(236eyes)withPACGwhounderwenttrabeculectomyduringthesameperiod.Theclinicalcharacteristics,includingclinicalpresentations,surgicalresultsandcomplicationsweree7、valuated.Datawereanalyzedwithapairedttestandachi-squaretest.ResultsThemeanageoftheyoungerpatientswithPACGwas(32.8~5.7)years.Themajorityofthemwerefemale(75%).Themeanaxiallengthwas(21.1±1.9)mm.Plateauiriswasthemostcommonunderlyingetiology(9l%),andonly1case(2eyes)waspupillaryblock.8、Themeanfollow-upperiodwas(24.8~6.3)months.There
4、ngerpatientsSUNHong.YUANZhi—lan,YULing—mei*,HUChun-ling.DepartmentofOphthalmology,theFirstAffiliatedHospitalofNanjingMedicalUniversity,Nanjing210029,ChinaCorrespondingauthor:YUANZhi-lan,Email:zhilanyuan@vip.sincacom【Abstract】ObjecfiveToevaluatetheclinicalcharacteristicsofyounger
5、patientswithprimaryangle—closureglaucoma(PACG).MethodsRetrospectivecasecontrolstudy.Twelvepatients(22eyes)aged40oryoungerwithaconfirmeddiagnosisofPACGfromJanuary2006toJuly2010wereinvestigated.Atthetimeoftheinitialdiagnosis.aUpatientswereinthemiddleorlatestageanddidnotfeelsignifi
6、cantpain.Eighteeneyesunderwentsurgicaltreatment.Fullophthalmicexaminationswereperformed.Theywerecomparedto217olderpatients(236eyes)withPACGwhounderwenttrabeculectomyduringthesameperiod.Theclinicalcharacteristics,includingclinicalpresentations,surgicalresultsandcomplicationsweree
7、valuated.Datawereanalyzedwithapairedttestandachi-squaretest.ResultsThemeanageoftheyoungerpatientswithPACGwas(32.8~5.7)years.Themajorityofthemwerefemale(75%).Themeanaxiallengthwas(21.1±1.9)mm.Plateauiriswasthemostcommonunderlyingetiology(9l%),andonly1case(2eyes)waspupillaryblock.
8、Themeanfollow-upperiodwas(24.8~6.3)months.There
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