女性冠心病临床特征与冠状动脉病变特点分析

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1、女性冠心病临床特征与冠状动脉病变特点分析【摘要】目的探讨女性冠心病的临床特征与冠状动脉病变特点，以提高诊治水平。方法以男性为对照，回顾性分析246例女性冠心病患者的临床资料及冠状动脉造影结杲。结果女性冠心病发病年龄较男性晚(PvO.05);绝经为女性冠心病的特殊危险因素，绝经后雌二醇水平降低，脂质代谢紊乱加重;高血床、高血脂、肥胖及糖尿病是女性冠心病的重要危险因素，有高血压、糖尿病、肥胖者显著高于男性(PvO.05);女性吸烟者显著低于男性(P<0.05)o女性不典型心绞痛及非特异性ST-T改变多于男性;女性急性非ST段抬高型心肌梗死显著高于男性，而急性ST段抬高型心肌梗死显著低于

2、男性(PvO.05)。女性冠状动脉病变以单支病变多见，左前降支最易受累，女性多支病变多于男性(P<0.05)o女性选择性介入治疗明显少于男性(PvO.05)。结论女性冠心病具有独特的临床特征及冠状动脉病变特点，应加强对女性冠心病防治的研究。【关键词】女性;冠心病;临床特征;冠状动脉造影［Abstract］ObjectiveToinvestigatetheclinicalcharacteristicsofcoronaryheartdiseaseandfeaturesofcoronaryarterylesionsinfemalepatientswithcoronaryheartdise

3、ase(CHD)inordertoenhancethediagnosticandtherapeuticlevels.MethodsTheclinicaldateandresultsofselectedcoronaryangiographyin246femalepatientswithCHDwereretrospectivelyanalyzed,and358malepatientswithCHDwereservedasthecontrols.ResultsTheageoffemalepatientswithCHDwassignificantlyolderthanthatofmales

4、(P<0.05),andmenopausewasspecialriskfactorforfemalepatientswithCHD,Thedecreaseofestradiolaftermenopause,aggratatedlipidmetabolicdisorder,hypertention,hyperlipidemia,obesityanddiabetesmellitusweremajorriskfactorsinfemalepatientswithCHD.Theincidencesofdiabetes,hyperlipidemiaandobesityinfemalepati

5、entswithCHDweresignificantlyhigherthanthoseinmales(P<0.05),however,thenumberoffemaleofsmokingwassignificantlylowerthanthatofmales(P<0.05).Theatypicalanginapectorisandnon-specificityST-Tchangesinfemalepatientsweremuchmorethanthoseofmales,andtheincidenceofacuteNSTEMIinfemalepatientswassignifican

6、tlyhigherthanthatinmales,however,theincidenceofacuteSTEMIwassignificantlylowerthanthatinfemales(P<0.05).ThesinglevessellocalizedstenosisinLADwastypicallesionsinfemalepatients,andmultiple-vessellesioninfemaleswasmuchmorethanthatinmales(P<0.05).ThefemalepatientswhochosePCIwereobviouslylessthanma

7、lepatients(P<0.05).ConclusionTherearespecialclinicalcharacteristicsandfeaturesofcoronaryailerylesionsinfemalepatientswithCHD,sothestudyonthepreventionandtreatmentforCHDinfemalepatientsshouldbeenhanced・【Keywords］female;coronaryheartdisea