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1、咪瞠安定联合异丙酚在电子胃肠镜检查术中临床应用[摘要]目的:研究静脉麻醉咪哩安定和异丙酚联合应用于内镜检查中的可行性和安全性。方法:应用静脉麻醉胃肠镜检查226例作为观察组,常规胃肠镜检查238例作为对照组。胃肠镜检查均比较两组检查过程中的反应、操作时间及检查前后的心率、血压、血氧饱和度变化。结果:观察组所有患者无不适,愿意复检者217例(96%);而对照组胃镜167例(93%)患者难受、肠镜58例(100%)患者难受,愿意复检者78例(33%)o观察组5〜10min内均完全清醒,均未遗留痛苦回忆。肠镜组镇静麻醉成功率观察组达回盲部48例(1
2、00%),对照组48例(83%)O观察组检查时间5〜10min完成,而对照组为8^30min,两组比较,差异有统计学意义。两组均无严重不良反应。结论:无痛性内镜检查简便易行安全,麻醉状态下胃肠镜检查术可消除患者的紧张、恐惧情绪,操作顺利,效果满意,值得推广应用。[关键词]静脉麻醉;咪吐安定;异丙酚;胃镜;肠镜[中图分类号]R614.2+4[文献标识码]C[文章编号]1674-4721(2011)08(b)-085-03Theclinicalapplicationofmidazolampluspropofolforgastrointestina
3、lendoscopyLIShuguangl,ZHANGLong2,RUANGuoyongl,LIANGAixial,QIUGuimeil1.DepartmentofInternalMedicine,thePeople,sHospitalofXinxingCounty,GuangdongProvince,Xinxing527400,China;2.DepartmemtofDigestion,theFirstPeople,sHospitalofGuangzhouCity,GuangdongProvince,Guangzhou510180,Chin
4、a[Abstract]Objective:Toinvestigatetheefficacyandsafetyofmidazolampluspropofolforgastrointestinalendoscopy.Methods:The226patientsasobservationgroupwerereceivedintravenousanesthesiagastrointestinalendoscopy,and238patientsascontrolgroupwerereceivedconventionalgastrointestinale
5、ndoscopy.consciousnessresponse,manipulationtime,cardiacrate,bloodpressure(BP),oxygensaturationofbloodoftheteogroupswereobserveredduringthestudy.ResuIts:Patientsinobservationgroupwereallwell,wantedtorechecking217cases(96%);Incontrolgroup,167(93%)patientsunwellinenteroscopean
6、d58(100%)patientsunwellingastroscope・Patientsinobservationgroupwereallcoldsoberin5~10minutes.48cases(100%)ofenteroscopereachedtoileocecusinobservationgroupand48cases(83%)incontrolgroup・Thereviewtimeofobservationgroupwas5-10minutesandcontrolgroupwas8~30minutes,therewasdiffer
7、encebetweenthetwogroups.Conclusion:Intravenousanesthesiaduringgastrointestinalendoscopycaneliminatepa/tients,fearmoodandimprovetheendoscopy.[Keywords]Intravenousanesthesia;Midazolam;Propofol;Gastroscope;Enteroscope胃肠镜诊疗是目前诊治消化道疾病最常用的主要方法,但有些患者对常规的胃肠镜检查产生一定的恐惧心理而拒绝检查,以至延误疾病的
8、诊断和治疗。无痛苦胃肠镜检查是在常规胃肠镜检查和治疗中应用一定剂量的镇痛及静脉麻醉剂,使患者在清醒镇静或浅睡眠状态下完成检查和(或)治疗,整个过程患者安全、舒适、无