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《Predictive value of urinary interleukin-6 for symptomatic urinarytract infections in a nursing home population尿白细胞介素-6对症状性尿的预测价值 疗养院人群的呼吸道感染》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、InternationalJournalofUrology(2016)23,168--174doi:10.1111/iju.13002OriginalArticle:ClinicalInvestigationPredictivevalueofurinaryinterleukin-6forsymptomaticurinarytractinfectionsinanursinghomepopulation12FredrikSundenandBj€ornWullt12DepartmentofSurgery,Helsi
2、ngborgHospital,Helsingborg,andDepartmentofMicrobiology,ImmunologyandGlycobiology,LundUniversity,Lund,SwedenAbbreviations&AcronymsObjectives:Tostudyurinaryinterleukin-6,interleukin-8andpyuriaduringepisodesofABU=asymptomaticasymptomaticbacteriuriaandsymptomati
3、curinarytractinfectionintheinstitutionalizedbacteriuriaelderly,andtoinvestigatetheroleofinterleukin-6asabiomarkerfordifferentialdiagnosis.IL=interleukinMethods:Levelsofinterleukin-6,interleukin-8andpyuriawereassessedin35olderUTI=urinarytractinfectionadultswi
4、thasymptomaticbacteriuriaandsymptomaticurinarytractinfectiontodefineWBC=whitebloodcellspossiblediagnosticthresholds.Inatwo-phaseinterventionstudy,theantibiotictreatmentforurinarytractinfectionbeforeandafterintroductionofurinaryinterleukin-6Correspondence:Fred
5、rikasabiomarkerwasthenassessed.SundenM.D.,DepartmentofResults:Asymptomaticbacteriuriapatientshadnoorlowlevelsofinterleukin-6,andSurgery,HelsingborgHospital,lowlevelsofinterleukin-8andpyuria.Womenhadlowerinterleukin-6andinterleukin-8SodraVallgatan5,S-25187th
6、anmen(P=0.05).Interleukin-6wastheonlymarkershowingsignificantincreasesHelsingborg,Sweden.Email:duringurinarytractinfectionepisodesinpatientswithbothasymptomaticbacteriuriafredrik.sunden@med.lu.seandurinarytractinfection,inpooled(P=0.042)andinpairedintra-indiv
7、idual(P=0.017)comparisons.Intheinterventionstudylectures,theincreaseduseofurineculturesandReceived29March2015;theintroductionofinterleukin-6asabiomarkerreducedantibiotictreatmentsby20%.accepted2October2015.Antibiotic-treatedurinarytractinfectionepisodeshadin
8、creasedinterleukin-6asOnlinepublication10Novembercomparedwithurinarytractinfectionepisodesnottreated(P=0.02),andascompared2015withasymptomaticbacteriuriapatients(P<0.0001).Thesensitivityandspeci