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1、1.AnesthAnalg.2004Sep;99(3):919-23.Levobupivacaine0.2%or0.125%forcontinuoussciaticnerveblock:aprospective,randomized,double-blindcomparisonwith0.2%ropivacaine.0.2%或0.125%的左旋布比卡因用于连续坐骨神经阻滞与0.2%罗哌卡因的比较(前瞻、随机、双盲实验)CasatiA,VinciguerraF,CappelleriG,AldegheriG,GrispigniC,PutzuM,RivoltiniP.Departm
2、entofAnesthesiology,IRCCSHSanRaffaele,ViaOlgettina60,20132Milan,Italy.casati.andrea@hsr.itIn60patientsreceivingelectivehalluxvalgusrepair,wecomparedtheefficacyofcontinuouspoplitealsciaticnerveblockproducedwith0.2%ropivacaine(n=20),0.2%levobupivacaine(n=20),or0.125%levobupivacaine(n=20)infus
3、edwithapatient-controlledsystemstarting3haftera30-mLbolusofthe0.5%concentrationofthestudydrugandfor48h(baselineinfusionrate,6mL/h;incrementaldose,2mL;lockouttime,15min;maximumincrementaldosesperhour,3).Nodifferenceswerereportedintheintraoperativeefficacyofthenerveblock.Thedegreeofpainwassim
4、ilarinthethreegroupsthroughoutthestudyperiod,bothatrestandduringmotion.Totalconsumptionoflocalanestheticsolutionduringthefirst24hwas148mL(range,144-228mL)with0.2%ropivacaine,150mL(range,144-200mL)with0.2%levobupivacaine,and148mL(range,144-164mL)with0.125%levobupivacaine(P=0.59).Thevolumeofl
5、ocalanestheticconsumedduringthesecondpostoperativedaywas150mL(range,144-164mL)with0.2%ropivacaine,154mL(range,144-176mL)with0.2%levobupivacaine,and151mL(range,144-216mL)with0.125%levobupivacaine(P=0.14).Asmallerproportionofpatientsreceiving0.2%levobupivacaineshowedcompleterecoveryoffootmoto
6、rfunctionascomparedwith0.2%ropivacaineand0.125%levobupivacaine,bothat24h(35%vs85%and95%;P=0.0005)andat48h(60%vs100%and100%;P=0.001).Weconcludethatsciaticinfusionwithboth0.125%and0.2%levobupivacaineprovidesadequatepostoperativeanalgesiaafterhalluxvalgusrepair,clinicallysimilartothatprovidedb
7、y0.2%ropivacaine;however,the0.125%concentrationispreferredifearlymobilizationoftheoperatedfootisrequired.2.AnesthAnalg.2004Aug;99(2):584-8,Nervestimulator-assistedevokedmotorresponsepredictsthelatencyandsuccessofasingle-injectionsciaticblock.神经刺激器帮助下引起的运
