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ID:40730529
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页数:20页
时间:2019-08-06
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1、articlesAnalysisofthegenomesequenceofthe¯oweringplantArabidopsisthalianaTheArabidopsisGenomeInitiative**Authorshipofthispapershouldbecitedas`TheArabidopsisGenomeIniative'.Afulllistofcontributorsappearsattheendofthispaper.......................................................................
2、.....................................................................................................................................................................................................The¯oweringplantArabidopsisthalianaisanimportantmodelsystemforidentifyinggenesanddeterminingth
3、eirfunctions.HerewereporttheanalysisofthegenomicsequenceofArabidopsis.Thesequencedregionscover115.4megabasesofthe125-megabasegenomeandextendintocentromericregions.TheevolutionofArabidopsisinvolvedawhole-genomeduplication,followedbysubsequentgenelossandextensivelocalgeneduplications,givingri
4、setoadynamicgenomeenrichedbylateralgenetransferfromacyanobacterial-likeancestoroftheplastid.Thegenomecontains25,498genesencodingproteinsfrom11,000families,similartothefunctionaldiversityofDrosophilaandCaenorhabditiselegansÐtheothersequencedmulticellulareukaryotes.Arabidopsishasmanyfamilieso
5、fnewproteinsbutalsolacksseveralcommonproteinfamilies,indicatingthatthesetsofcommonproteinshaveundergonedifferentialexpansionandcontractioninthethreemulticellulareukaryotes.Thisisthe®rstcompletegenomesequenceofaplantandprovidesthefoundationsformorecomprehensivecomparisonofconservedprocessesi
6、nalleukaryotes,identifyingawiderangeofplant-speci®cgenefunctionsandestablishingrapidsystematicwaystoidentifygenesforcropimprovement.Theplantandanimalkingdomsevolvedindependentlyfrombiologists,butwillalsoaffectagriculturalscience,evolutionaryunicellulareukaryotesandrepresenthighlycontrasting
7、lifeforms.biology,bioinformatics,combinatorialchemistry,functionaland12ThegenomesequencesofC.elegansandDrosophilarevealthatcomparativegenomics,andmolecularmedicine.metazoansshareagreatdealofgeneticinformationrequiredfordevelopmentalandphysiologicalproces
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