Comparison between sitagliptin and nateglinide on postprandial lipid levels The STANDARD study

Comparison between sitagliptin and nateglinide on postprandial lipid levels The STANDARD study

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时间:2019-08-06

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1、OnlineSubmissions:http://www.wjgnet.com/esps/WorldJDiabetes2013February15;4(1):-13wjd@wjgnet.comISSN194-935(online)doi:10.4239/wjd.v4.i1.©2013Baishideng.Allrightsreserved.BRIEFARTICLEComparisonbetweensitagliptinandnateglinideonpostprandiallipidlevels:TheSTANDARDstudyY

2、uichiKojima,HideyoshiKaga,ShinuHayashi,ToruKitazawa,YukoIimura,MakotoOhno,MichiyasuYoshitsugu,MutsunoriFujiwara,ToruHiyoshiYuichiKojima,HideyoshiKaga,ShinuHayashi,ToruKitaza-sampleswerecollectedatoneandthreehoursafterwa,YukoIimura,MakotoOhno,MichiyasuYoshitsugu,Mut-intake

3、ofatestmeal.TheprimaryoutcomemeasuresunoriFujiwara,ToruHiyoshi,JapaneseRedCrossMedicalwastheareaunderthecurve(AUC)ofapolipoproteinCenter,Tokyo150-8935,Japan(Apo)B48atthreehourspostprandially.Authorcontributions:KojimaY,KagaH,HayashiS,KitazawaT,IimuraYandFujiwaraMcontribut

4、edtoresearchdesign;Ko-RESULTS:TwentypatientswererandomlyassignedjimaY,OhnoM,YoshitsuguMandHiyoshiTcollectedthedata;tothesitagliptingroupandsixteenpatientswereran-KojimaYwrotethemanuscript;KagaH,HayashiS,KitazawaT,IimuraY,OhnoM,YoshitsuguM,FujiwaraMandHiyoshiTdomizedtothen

5、ateglinidegroup.All36patientstookcontributedtorevisingthemanuscript;andallauthorsapprovedthemedicationasdirectedbythephysicianinboththefinalversion.groups,andtheyallwereanalyzed.Apartfromanti-Correspondenceto:YuichiKojima,MD,JapaneseRedCrossdiabeticdrugs,therewasnodiffere

6、ncebetweentheMedicalCenter,4-1-22Hiroo,Shibuya-ku,Tokyo150-8935,twogroupswithrespecttothefrequencyofcombinedJapan.kojima_yuichi@med.jrc.or.jpuseoflipid-lowering,antihypertensive,and/oranti-Telephone:+81-3-34001311Fax:+81-3-34091604plateletdrugs.Thedosesofthesemedicationsw

7、ereReceived:September12,2011Revised:November29,2012maintainedduring12wkoftreatment.DetaileddietaryAccepted:January5,2013advice,togetherwithadequateexercisetherapy,wasPublishedonline:February15,2013giventothepatientssothatotherfactorsapartfromthetwotestdrugsweresimilarinth

8、etwogroups.Therewerenosignificantdifferencesofthebaselinecharacteristicsbetweenthetwogroups,exce

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