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ID:33209325
大小:1.21 MB
页数:35页
时间:2019-02-22
《柔肝灵颗粒治疗非酒精性脂肪肝(气虚血瘀证)的临床研究》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、陕西中医学院硕士学位论文柔肝灵颗粒治疗非酒精性脂肪肝(气虚血瘀证)的临床研究姓名:云小君申请学位级别:硕士专业:中医内科学指导教师:侯宝峰201204摘要lUIlUIIillll11111111Y2115378目的:探讨柔肝灵颗粒对非酒精性脂肪肝(气虚血瘀型)患者的I晦床症状、体征、肝功能、血脂以及影像学的影响,观察柔肝灵颗粒的临床疗效以及其安全性。方法:60例非酒精性脂肪肝患者随机分为治疗组30例(服用柔肝灵颗粒)、对照组30例(服用水飞蓟宾胶囊)。治疗组给予柔肝灵颗粒nlJli,一次lOg,每日3次。对照组:给予水飞蓟宾胶囊(水林佳)口
2、服,一次70mg,每日3次。两组均服药24周。用药期间观察指标包括:临床症状、肝功、肾功、上腹部CT、血脂系列(TG、TC)。疗程结束后复查肝功、肾功、血常规、血脂系列、上腹部C,r。结果:两组病例经治疗后分析,治疗组服用柔肝灵颗粒与对照组服用水飞蓟宾胶囊相比较在改善临床症状、消除肝脏炎症、降低血脂以及c1’影像学改善等方面,两种药物均有效。柔肝灵颗粒治疗非酒精性脂肪肝(气虚血瘀型)较水飞蓟宾胶囊,尤其在消除临床症状方面效果甚佳,经统计学处理具有统计意义(P3、有统计意义(P<0.05);在恢复肝功能方面其疗效较水飞蓟宾胶囊明显,治疗后两组比较具有统计学意义(P<0.01),治疗后CT影像学两组间比较无统计学意义(P>0.05);两组临床疗效比较,治疗组总有效率是83.3%,对照组总有效率是70%,经统计学处理具有统计学意义(p4、eatmentnonaIcohoIicfattyIiverdisease(qiastheniacausingbIoodstasiS)ofCIinicaIresearchAbstractObjective:Itistostudytheinfluenceoflivernourishinggranulesontheclinicalsymptoms,signs,theliverfunction,bloodfatandiconographyofpatientsofnonalcoholicfattyliverofqideficiencyandblood5、stasis.Italsoobservestheclinicaleffectsandthesecurityoflivernourishinggranules.Method:60patientsofnonalcoholicfattyliverarerandomlydividedintotreatmentgroupof30cases(takinglivernourishinggranules)andcontrolgroupof30cases(takingMilkthistlePenncapsule).Thetreatmentgroupisgiv6、enlivernourishinggranules,whicharetakenorallylOgonce,3timeseachday.ThecontrolgroupisofferedMilkthistlePenncapsule(Silibinin),whicharetakenorally70mgonce,3timeseachday.Themedicationofbothgroupslastsfor24weeks.Duringthemedication,theobservationindexesinclude:clinicalsymptoms7、,liverfunction。kidneyfunction,upperabdominalCT(1iver,gallbladder,pancreasandspleen),bloodfatseries(TGandTC).Afterthecourseoftreatment,thereexaminationofliverfunction,kidneyfunction,bloodroutine,bloodfatseries。upperabdominalwillbecarriedout.Results:afterthetreatment,itturns8、outthatbothgroups(thetreatmentgrouptakinglivernourishinggranulesandthecontrolgrouptakingM
3、有统计意义(P<0.05);在恢复肝功能方面其疗效较水飞蓟宾胶囊明显,治疗后两组比较具有统计学意义(P<0.01),治疗后CT影像学两组间比较无统计学意义(P>0.05);两组临床疗效比较,治疗组总有效率是83.3%,对照组总有效率是70%,经统计学处理具有统计学意义(p4、eatmentnonaIcohoIicfattyIiverdisease(qiastheniacausingbIoodstasiS)ofCIinicaIresearchAbstractObjective:Itistostudytheinfluenceoflivernourishinggranulesontheclinicalsymptoms,signs,theliverfunction,bloodfatandiconographyofpatientsofnonalcoholicfattyliverofqideficiencyandblood5、stasis.Italsoobservestheclinicaleffectsandthesecurityoflivernourishinggranules.Method:60patientsofnonalcoholicfattyliverarerandomlydividedintotreatmentgroupof30cases(takinglivernourishinggranules)andcontrolgroupof30cases(takingMilkthistlePenncapsule).Thetreatmentgroupisgiv6、enlivernourishinggranules,whicharetakenorallylOgonce,3timeseachday.ThecontrolgroupisofferedMilkthistlePenncapsule(Silibinin),whicharetakenorally70mgonce,3timeseachday.Themedicationofbothgroupslastsfor24weeks.Duringthemedication,theobservationindexesinclude:clinicalsymptoms7、,liverfunction。kidneyfunction,upperabdominalCT(1iver,gallbladder,pancreasandspleen),bloodfatseries(TGandTC).Afterthecourseoftreatment,thereexaminationofliverfunction,kidneyfunction,bloodroutine,bloodfatseries。upperabdominalwillbecarriedout.Results:afterthetreatment,itturns8、outthatbothgroups(thetreatmentgrouptakinglivernourishinggranulesandthecontrolgrouptakingM
4、eatmentnonaIcohoIicfattyIiverdisease(qiastheniacausingbIoodstasiS)ofCIinicaIresearchAbstractObjective:Itistostudytheinfluenceoflivernourishinggranulesontheclinicalsymptoms,signs,theliverfunction,bloodfatandiconographyofpatientsofnonalcoholicfattyliverofqideficiencyandblood
5、stasis.Italsoobservestheclinicaleffectsandthesecurityoflivernourishinggranules.Method:60patientsofnonalcoholicfattyliverarerandomlydividedintotreatmentgroupof30cases(takinglivernourishinggranules)andcontrolgroupof30cases(takingMilkthistlePenncapsule).Thetreatmentgroupisgiv
6、enlivernourishinggranules,whicharetakenorallylOgonce,3timeseachday.ThecontrolgroupisofferedMilkthistlePenncapsule(Silibinin),whicharetakenorally70mgonce,3timeseachday.Themedicationofbothgroupslastsfor24weeks.Duringthemedication,theobservationindexesinclude:clinicalsymptoms
7、,liverfunction。kidneyfunction,upperabdominalCT(1iver,gallbladder,pancreasandspleen),bloodfatseries(TGandTC).Afterthecourseoftreatment,thereexaminationofliverfunction,kidneyfunction,bloodroutine,bloodfatseries。upperabdominalwillbecarriedout.Results:afterthetreatment,itturns
8、outthatbothgroups(thetreatmentgrouptakinglivernourishinggranulesandthecontrolgrouptakingM
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