加味生脉饮治疗老年下肢动脉硬化闭塞症的临床疗效观察

《加味生脉饮治疗老年下肢动脉硬化闭塞症的临床疗效观察》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、提要目的：观察加味生脉饮联合前列地尔治疗老年下肢动脉硬化闭塞症的临床疗效，探讨中医药在治疗老年下肢动脉硬化闭塞症的优势。方法：选取符合标准的60例老年下肢动脉硬化闭塞症患者随机分为2组，对照组30例给予前列地尔10μg，加入0．9%氯化钠注射液10mL中静脉推注，每天1次，治疗组30例，在对照组的基础上给予中药加味生脉饮，泡水代茶饮，每日1剂，14天为1周期，连用6个周期为一疗程。观察治疗前后相关指标的改善情况。通过统计学处理比较治疗组和对照组之间的临床疗效。结果：治疗组总有效率为93.3％，疗效优于对照组的70％（P＜0.05）。治疗组患者临床症状和体征

2、、内皮四项及踝肱指数有明显的改善，全血粘度、血脂及高敏C反应蛋白明显降低，两组比较均有显著性差异（P＜0.05）。两组在治疗过程中均未发生不良反应。结论：加味生脉饮联合前列地尔对老年下肢动脉硬化闭塞症有着良好的治疗作用，加味生脉饮在改善临床症状和体征、内皮四项、踝肱指数、全血粘度、血脂及高敏C反应蛋白较前列地尔在老年下肢动脉硬化闭塞症的治疗上有明显优势。关键词下肢动脉硬化闭塞症；老年；加味生脉饮；TheClinicalResearchofFlavoredShengMaiYinCareforElderlyLowerExtremityArteriosclero

3、sisObliteransSpeciality：InternalMedicineofTraditionalChineseMedicineAuthor：ChenLeijieTutor：ProfessorLiRuiAbstractObjective:ToobserveclinicaleffectsofcombinedtherapyofChineseandWesternmedicineonatherosclerosisobliteransinlowerextremities.Methods:60casesofatherosclerosisobliteransin

4、lowerextremitieswererandomlydividedinto30casesintreatmentgroupand30casesincontrolgroup.ControlgroupwasinjectedliposomalprostaglandinE-110μgthroughveins,onceperday.Basedonthetreatmentofcontrolgroup,treatmentgroupweregivenoraldecoctionofflavoredShengMaiYin.14dayswere1courseoftreatme

5、ntforbothgroups.Theeffectswereobservedafter6courseoftreatment.Observedbeforeandaftertreatmentofimprovingrelevantindicators.Throughthestatisticalprocessingcomparisonbetweentreatmentgroupandcontrolgroupthecurativeeffect.Results:Totaleffectiverateoftreatmentgroupwas93.3%,betterthanof

6、controlgroup70%(P＜0.05).ThesymptomssignsendothelialFourandankle-brachialindexofaffectedlimbsimprovedobviously.WholebloodviscositybloodlipidandHs-CRPdecreasedsignificantlycomparisonbetweentwogroupsindicatingthatthereexistedstatisticaldifferences(P＜0.05).Twogroupsinthehealingprocess

7、alldidnothappenadversereactions.Conclusion:TheflavorShengMaiYinjointalprostadilfatemulsiominjectionforolderlowerextremityarteriosclerosisobliteranshasgoodcurativeeffect.TheflavorShengMaiYininimprovedclinicalsymptomsandsigns,endothelialfour,anklebrachialindex,wholebloodviscosity,bl

8、oodfatandHs-CRP,atopinolderlowere