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时间:2018-10-28
《调强放射治疗同步替吉奥治疗高龄食管癌患者的疗效观察》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、调强放射治疗同步替吉奧治疗高龄食管癌患者的疗效观察【摘要】目的:探讨常规分割调强放射治疗同步替吉奥治疗高龄食管癌患者的疗效。方法:选择2011年10月-2013年10月门诊和住院治疗的高龄管癌患者53例。根据治疗模式不同,分为同步组和对照组,同步组采用调强放射治疗同步替吉奥治疗,对照组采用单纯调强放射治疗。结果:同步组较对照组的副反应略高,但差异无统计学意义(P>0.05);同步组和对照组患者总有效率分别达到84.00%和57.14%,差异有统计学意义(P=0.033);同步组和对照组患者12个月随访期内的中位无进展生存期分别为
2、10.84个月和9.36个月,差异有统计学意义(P=0.044),同步组和对照组患者的1年生存率分别为88.0%和85.7%,差异无统计学意义(P=0.75)。结论:调强放射治疗同步替吉奥治疗高龄食管癌患者的疗效肯定。【关键词】调强放疗;替吉奥;食管癌中图分类号R735.1文献标识码A文章编号1674-6805(2015)9-0004-03ClinicalAnalysisofElderlyEsophagealCancerPatientsTreatedwithIntensityModulatedRadiationTherapyan
3、dTegafurGimeracilOteracilPotassiumCapsule/WANGWu-long,WANGChun-lei,YUBai-qing,etal.//ChineseandForeignMedicalResearch,2015,13(9):4-6【Abstract】Objective:Tostudytheclinicalanalysisofelderlyesophagealcancerpatientstreatedwithintensitymodulatedradiationtherapy(IMRT)andTe
4、gafurGimeracilOteracilPotassiumCapsule.Method:53elderlyesophagealcancerpatientsfromOctober2011toOctober2013wereselected.Accordingtothedifferenttreatmentmodalities,theyweredividedintothesynchronouschemotherapygroupandthecontrolgroup,thesynchronouschemotherapygroupwast
5、reatedwithIMRTandTegafurGimeracilOteracilPotassiumCapsule,thecontrolgroupwastreatedwithIMRT.Result:Thesideeffectsofthesynchronouschemotherapygroupwashigherthanthatofthecontrolgroup,butthedifferencehadnosignificantdifferencebetweentwogroups(P〉0.05);thetotaleffectivera
6、teofthesynchronouschemotherapygroupwas84.00%,thecontrolgroupwas57.14%,therewasstatisticallysignificantdifference(P=0.033),themedianprogressionfreesurvivalofthesynchronouschemotherapygroupandcontrolgroupwere10.84monthsand9.36months,therewasstatisticallysignificantdiff
7、erence(P=0.044),thesurvivalrateinoneyearofthesynchronouschemotherapygroupandcontrolgroupwere88.0%and85.7%,therewasnostatisticallysignificantdifference(P二0.75).Conclusion:EffectivenessofelderlyesophagealcancerpatientstreatedwithIMRTandTegafurGimeracilOteracilPotassium
8、Capsuleisdefinite.【Keywords】Intensitymodulatedradiationtherapy;TegafurGimeracilOteracilPotassiumCapsule;EsophagealcancerFirst-autho
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