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1、Alcohol,AlcoholUseDisordersandBurdenofDiseaseJürgenRehm1-31)CentreforAddictionandMentalHealth,Toronto,Canada2)DallaLanaSchoolofPublicHealth,UniversityofToronto3)TechnischeUniversitätDresden,ClinicalPsychologyandPsychotherapyThankyou!Thisworkwouldnothavebeenpossible:withou
2、ttheparticipantsoftheGlobalBurdenofDiseaseComparativeRiskAssessmentforalcohol(morethan500contributors;coregroup:G.Borges,G.Gmel,B.Grant,K.Graham,C.Parry,J.Rehm,R.Room)withoutthesupportorNIAAA(“Alcohol-andDrug-AttributableBurdenofDiseaseandInjuryintheUS”;contract#HHSN26720
3、0700041C)andalltheexpertswhocontributedtotheworkshopsfromNIH,CDCandCAMH.ThanksalotforCDC,NIAAA,NIDAfororganizingtheseworkshops!withouttheTorontoteam:D.Baliunas,G.Gmeljr.,H.Irving,T.Kehoe,J.Patra,L.Popova,M.Roerecke,A.Samokhvalov,B.TaylorwithoutthecollaborationofU.Frickwit
4、houtthecollaborationoftheAlcoholResearchGroup(J.Bond,T.Greenfield,W.Kerr,Y.Ye)age-weightedand3%discounted(WHOnormvalues)Impressivenumbers,but.....weneedtoknowtheprocessanditsassumptionsbeforewecancommentonthemforinstance:Whichdiseasecategoriesareconsideredalcohol-attribu
5、tableandwhy?Howistheimpactofalcoholmodelled?WhatareDALYsandwhyaretheydiscounted?Etc.,etc.TopicscoveredModeltoestimatealcohol-attributablediseaseburdenWhatdiseasecategoriesarerelatedtoalcoholandwhatisthedose-responserelationship?Howtomeasureexposureforestimatingalcoholattr
6、ibutableburdenofdisease?TheroleofdisabilityweightsinaburdenofdiseaseframeworkTopicscoveredModeltoestimatealcohol-attributablediseaseburdenWhatdiseasecategoriesarerelatedtoalcoholandwhatisthedose-responserelationship?Howtomeasureexposureforestimatingalcoholattributableburd
7、enofdisease?TheroleofdisabilityweightsinaburdenofdiseaseframeworkSocietalFactorsDrinkingcultureAlcoholPolicyDrinkingenvironmentHealthcaresystemPopulationgroupGenderAgePovertyMarginalization(individual)CurrentlyusedmodelforalcoholCRA2005BasicformulawherePaistheprevalenceof
8、lifetimeabstainersRRaistherelativeriskoflifetimeabstainers(setto1)Pexistheprevalenceofformerdrin