sumo-1修饰因子的作用

《sumo-1修饰因子的作用》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。

1、SUMO-1修饰因子的作用2006??9?o?824???83?U????????????????JournalofYangzizouCollegeofEducationSept.2006Vol.24,No.3SUMOZ?1?????????????:????IJV?aZ?????MS?a??????2(1.?????????????U?d???a????????225002;2.?????)???B?????a????????225009)????:SOMO-1??ZXZ?ZQ?????????aZB?????:?k?????f???6???a??

2、???????????????????m???)???u?YZ!D0SOMO-1?p?????q???:Z??U?K????ZT?a????Zf???????????p?????6??D0?8??????Z?SUMO-1?????:?9?????????:D0???P??:SOMOZ?1;????????;?????p??ZT???3????:Q291???P?J???2:A?????d??:1008Z?6536(2006)03Z?0009-05???M???????????????:?????f?????????:???????k?????????

3、??:?????6???????P???????p??D0???M???????M?????????k?????????n?a?p????????????????Z????o?D???????????:??????Zr???v?????f?y????????D0?????????M?d?e???a???j?%ATP?????????a???M??C??Zf?????0?)???M???B??E1???~???:????????Z????o?a???gElZ????M?l?o??;ElZ????M?l?o?????3???M????????Z?ZQ??

4、?M???o??Ego???8Z?ZQ???M?3???:??????E3?????dZn?????D??????ZrZ??f?a???dZ?Z????M?3??????Zf?qZ?ZQ???M?3????48?q???:???????????a?p?????MZ????M?0???????a???gZ????p?????M??D0?s?f???M?d???????????????????g???q???a?p?????MZ???????ZX??ZQ???M?3?????????-?:D0?????????????M?d?????kZ????????

5、??q??ZX????????D0????????Z?Z??e???????a????ZT?????:Z??????M???????M?d???????e??D0???M???b??????????????????????????Z???????Z????M?e????????D0?e?????????????g????Zl??????Zf?????:???q???a???q?e?????p???k???g??ZwZ??Y???????M????????Z?1(SUMO-1)121?a?????????:Z??'?u?U?K????ZTD0??Z??

6、???ZT???:Zu??SUMO????Z???MeSUMO-l,SUMO-2??SUMO-3D0???q???e??ZB????ZT?:SUM(DEZ?1?????aSUMOZ?1?%101ZQ?:???????g?a?3????ZX11.5kDa?a?u18%???:???????cZf???M???a[31D0??Z????c?a???d?aSUMO?????M?"?uZ??????b??Zu??????D0SUMOZf???????????o????(????ZXD0umoylation)?k?p??SUMO??3Mt???????????

7、????:????????D0Z??:??Zw?????g?0???PD0SUMOZ?1Z??8?qZ??K???l?o?????????K???a???????:Z??????Y?MZT?k???????????a?:???p??????????ZT?"?u?'????[MS]D0sumoylatioD0?p???pZQ?????????vD0sumo?kZ??q???????????Y???o?g?a???q????????????????Z????~???:????????(SENPs/SUSPs)????D0Zf???M?d?e?????b?

8、asumo-1??Z???Z????o?D???????????:????????:Z??:??Zr?E??