放射治疗题库

《放射治疗题库》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。

ᶭ⚪1998E.55GyB.T1.᜻ᜧῼḄ!"#ᢣ%6.ᾯ()*᜻+᷈ᶭC.Bᜫ/Ḅ0⌕(2#%A.ᨵῼ56ᜧḄ7D.B=>A.89:;B.?ᱏAῼBCḄ7E.Burkitt᷈B.D✄:;C.ῼ6ᙽᨬᜧMNT5OT6?P11.ῼ5*᜻᷈;QRMSTU1/3C.XYZ)D9ᔠ\]⊈Ḅ_`%D.ῼ6ᙽᨬᜧMN?PᨬᜧRD.5ab:;A.15%O25%MSTU2/3E.ef:;B.25%O30%E.ῼ6ᙽᨬᜧMNT5'T6?PRMSTU1/27.jkl*᜻᷈ᨬ᧕C.35%O45%opḄq):;Yr#%2.ᙠ᜻5⁚uᓄwxy%D.45%O55%A.ῼ5A.z{᝕ឋE.65%O75%B.ῳ5B.z{ᵱឋ12.ូឋ*᜻᷈%C.5C.ὁzὅA.7wxD.⍝D.ὅB.wx()y5᜜ᘤE.E.ῼ:;C.wxῼ:;8.()yᡡ᪻ḄIA*3.ᙠ᜻)¡:;Ḅ᜻᷈Ḅ
¢£¤`%D.wxe¥D9:;5¦%A.§¨ὡª¢E.xD9:;A.«¬5B.“®”°¢+ὡª¢13.w²
ᶭ³ḄὊ:ᑺ¶`%B.ῳ·¸5C.☢⚠ὶᔠ¢+⚠A.25GyC.·5┝DA¦¢B.30GyD.ῳ+5D.☢⚠ὶᔠ¢C.35GyE.5E.“®”°¢+ᧅ¾¢D.45Gy4.᜻IbḄᶭÀᫀ#%9.ូឋ*᜻᷈Âᮤ³ÄÅÆḄÇஹIVE.55GyA.Êᐰ5᯿
7%14.eÍÎÆ⊈Ï᷈ḄÐ₞ᶭᑺ¶`%B.ᐰ5᯿
A.ÒÓÔÕ᩽Ḅᐰ×ᓄᶭA.30~40GyC.ᐰ5᯿
+ᓄᶭB.ÒÙÚᜧ☢Õ᯿
B.15O20GyD.ᓄᶭ+ᐰ5᯿
ᶭC.20O30GyE.ᓄᶭ`0C.ÒÙÚᐰ×ᓄᶭ+ᶭD.40O45Gy5.᜻Ḅ᪷ᑺ¶`%D.ÒÙÚD9ÜÝᶭE.45O50GyA.25GyE.Þ⌱à“ááâ”Ḅ15.ãäåæᶭḄçè#%B.30GyᶭéᶍA.☰¦!rìíîC.35Gy10.ïῚNHLwxḄᳮõ#%B.öw÷øùúìûüD.45GyA.᜜ᕜTC.þÿᓫ᯿1

1D.T3bA.gjᓫ=Rᮤ$«¬3cmD.E.T4bB.ᨵᓫ¯°±Ḅ²³´µ¶E.21.▢ᶭḄC.R·¸¹35º16.$%&ᶭᑺ()*ᵨ,*D.R·¸¹ᜧ55ºA.35GyA.3ᶭ4562E.ᨵgj¼½¾B.40GyB.&ᶭ9:&26.gjὅ_=ᮤ2X2cmÀ᜜C.50Gy<=Á▲VÃ᷈ᑗ◀Ã᷈ᑗÇ▢ឋ²³ÈÉÊ᩵▢ឋÌ6ᜐᳮ&D.60GyC.᪷ឋᶭ@ᶇ▢ᶭÎᵫÐMifi*BᢝDᳮFGE.65GyA.ᐰgj+ᑁg´µ¶D.ᶭHGIᑮKL17.NᨬPQḄRᳮST,*ᵨB.ᐰgj+ᑁgÖ┝}´µ¶A.UVWXE.ᶭHG)YZC.ᐰgj+ᑁgஹ²³ஹ┝}ᶭ´µ¶B.⚩\WX22.I^_WXḄៜ᳛):D.ᓫÙᐰgj᯿C.cdWXA.85%E.ᐰgj+²³´µ¶᯿D.gᜮijB.90%E.lC.93%27.Ú3pᦪÜὅÝ)gj᪷ᡈ18.3ᶭT3ῴnᨵp5Rqᦋà᪷&ᶭ*rstᑮᑖv9*D.95%A.ráâãäåᑴ᳛ÖD᳛A.15%w25%E.98%B.ráâãäåᑴ᳛Ö9:çB.25%w35%23.I^_WXḄ⚜■᯿ᜐèU᳛ᑺ(,*C.35%w45%C.ãäåᑴ᳛éê£ᜧA.20w25Gy/3~4ᕜD.40%w50%D.rGáâD᳛HRëᙠB.25w30Gy/3~4ᕜᑁÁ▲ஹ²³´µ¶íèUὅE.50%s}C.30'35Gy/3w4ᕜE.rG9:D᳛19.ῴn&ᶭᨬ᧕DḄᘤ,*D.35w40Gy/3w4ᕜ28.îï𴵶ñ*A.ῴnE.40w45Gy/4w5ᕜA.²³´µ¶Ḅò•ôB.$%24.3ᑡjP᜜᯿᪷ឋB.²³´µ¶Ḅòõôᶭᑺ()*C.⍝C.²³´µ¶ḄòöôA.40GyD.%D.┝v´µ¶B.50GyE.E.£ñs}´µ¶÷C.60Gy20.ῴnJewettWarshallᑖḄC29.vᑡᩩ£ùᔠgjû᪵ḄᱯAJCCᑖḄ*D.70Gyþ*A.T2E.80GyA.ÿ
᷈B.T4a25.gjὅvᑡ¡B.ᨵ¢£〉¥⌱§@¨6+᪷ឋC.T3aᶭC.
᷈ᜧᕈឋ2

2D.᳛!B.ᵯ#$B.ᓫ&'ᶭE.⚜+,ឋ-./0C.12#C.᪷4ឋ'ᶭ+Ὶᑁ'ᶭ30.:;<=/>?@A+᪷4ឋ'ᶭBD.!CX$+ᵯ#$᪷4AE'ᶭ,FD.AG'ᶭ+@A4ᶭE.!CX$+12#A.GὅJKLᑴ᳛NE.᪷4ឋ'ᶭ+ᓄᶭ35.PQᙠSTUVW᪀Ḅ/B.᪷4AJKLᑴ᳛N[Ḅ⚜+0F39.]^./_`abcdefgὃ⇋jFC.᪷4AJKLᑴ᳛NkQlA.S᪀᳛JA.◖nᡠpB.᪀D.qr4ᶭstḄJKLᑴ᳛uB.vwᾭyᕜ{
Ql᳛|}C.G᪀ᜧᡠpE.GὅJKLᑴ᳛NkqὅQD.+᪀C.~
ᜧᡠpl᳛|}E.G᪀+᪀D.^.
᷈JK᜜ᡠp31.ᾙ᷈᡽ᜧᑗ◀A+'4ᶭ2ᵨᢈA᪷4jDT65Gy,ᑖᙠ36.஺,ḄgᵨE.┝ᜮ¡¢Ḅa£ῼ᯿ᑺu§¨©qªFF
ᜧᡠpA.45Gy;60GyA.gᔜr¯°Ḅ40.WNᑖᓄ±/᪷4'ᶭ+²³P`'gឋᵨ´ᦋ¶ᑖª4ᶭ·b~q¸ᮤº»j1.5~2cm,ᚁB.50Gy;60GysᫀḄᑺᣚÁÂ4ᶭsᫀÃFC.40Gy;55GyB.஺Ä,ÃÅÆA.@A4ᶭgḄᳮÈD.45Gy;55GyB.ᓄᶭ+@AC.Éᵨ´ÊÁÅÆE.40Gy;60GyḄὊÌឋC.ᓄᶭ+JK'ᶭ32.ᙠÍÎᾙ᷈ḄA+'ᶭ2gD.⊝
᷈Ḅ'D.JK'ᶭÐÑ᯿ÍÎᐰᕜv⌕ÃjÔFÕÖឋE.Qᱥ4ᶭA.ØÙÚÛḄញឋ'gE.v⌕ÃW¸ᳮÈÝᵨÞᜧ41.ßᱏá~ᕜᨵWº»j2cm⁚ã,B.ØÙäᾙḄå;'æçðñòóᨵôõö┛ᓄBøùú37.'Qᱥé2Ḅ4“R”í⊤ïᮤᑡV¸üýÉCឋᨬᜧFC.ÐÑÍÎPQ¡
ÿA.᪶ᳫD.☟ᾭḄA.RBE,OER,SER,PRB.┯᪀᷈E.ᾭḄB.ᙠᑖᶭ!"#᷈$%&'()*+,Ḅ-.᝱C.1234#33.6'(ᾙ᷈ᨬ&9:;Ḅᘤ=>?ᓄḄᭆBD.CDA.C.%&'()*ḄEᶭFGḄHIJKE.LDB.MD.#᷈NOPḄQIR42.ᵱឋW75ZWὁ᠒12#,▰^ឋC.ᾯ`ᦔGḄ⊤,c᫱eWcfghW1jk2lm50%,pᱏrCT,tuᨵ-ᑖwஹᨵyzrD.{E.#᷈EOᱥ}Ḅ~pᐵᑗḄ#ᙽW#ᜧ⌕ᜧW'(}mCDWᨬḄEOE.>38.ᵱឋ,55Z,37cmᐙ34.!CD(T1N0)£ᮤ᜜¦§¨©6'(ªW᜜«cᒹஹA.£ᮤ+®ῼ°±᯿Oᵨ®ῼp´r23´ᐵᑗW¼WᑺlDT60Gy/30/6ᕜµ¶Ἥ¸¹Wᨬᶭºᫀ>A.ÃgX(r)PB.£ᮤ+®ῼ°±A.᪷ឋEᶭ¼WᑺlDT40Gy/20/4ᕜ3

3PÇÈ2cmmAÉWÊᔣ᜜3cmmC.£ᮤÌcÍᬪÏÐ᯿OWBÉA.A᷈CCᨵᐸFᔠHIᑺlDT60Gy/30/6ᕜJᓽLMNᜐᳮD.AÉâã▢⍝ä◖uD.£ᮤÑWᑺlDT60Gy/302cm,PÇÈ2cm;BÉâãçῚB.P2QR&STU/6ᕜE.AஹBèÉéêὅḄìC.P2VWQR&SXYE.£ᮤ+®ῼ°±íî#᷈JKR`ïR`¼WᑺlDT40Gy/20/4ᕜD.P2[ᔠH\ᾯ^47.᝕ឋW60ZWñòW▢⍝43.ÒÓÓÇ"◣ᑖmHÕ"◣Róᑣ±⊈1öWᨵµ¶Ἥ¸÷WE.P2[ᔠH`aᐰùúû--ýWþÿ8ᕜA.2Õ"◣ᜧ-ᑁ51.cᵨeᑺ.᳛ghijᶭA᷈LᐸῚ8cm,ᳮ⚠kᑺ.lB.3Õ"◣ᑁᑖᓄ!஺#⌱%&ᶭ(ᑁ&ᶭa*ஹF*ᑺ.0A.mnᑺ.᳛ghijᶭ᪵C.4Õ"◣12:B.epnᑺ.᳛ghijᶭD.5Õ"◣A.A*35~45GyF*40>45GyC.npnᑺ.᳛ghijᶭE.6Õ"◣B.A*40~45GyF*D.q᯿᜜᯿Sᑺ.44.▢⍝Ø#᷈ÙÚEOᶭÛWាÝ45~50GyḄᶭºᫀmE.m᜜᯿Sᑺ.tuvwC.A*45~50GyF*A.ᓫß▢⍝Ὶᑁ᯿O45ஹ50Gy52.yz{᯿S|}~ᑣ1B.▢⍝Ὶᑁ᯿SwῚᑁ᯿D.A*50>55GyF*A.⍳᯿ÇÈÉS45>50GyB.ÊËÌÍC.▢⍝Ὶᑁ᯿SwῚ᜜᯿SE.A*50>55GyF*60>65GyC.ᢥᔆ¯ÐÑḄÒᓄÓD.▢⍝Ὶᑁ᯿SwῚ᜜᯿S᜜᯿SUᒹῳḄ48.®¯ូឋA᷈²³D.ᢥÔÕÍÖ᯿SjᶭḄ5´Rµ᳛2E.ᢥQUIMBYÍÖE.ᓫ᜜᯿SᓽVA.30%53.NÜghijᶭḄᱯÞ45.⚠!eᑺ.᳛᯿SាB.40%ᑺ.LUὃ⇋A.&S}ßàᓄC.50%A.᜜᯿SB*40~50GyB.⍩âD.60%B.A*kᑺ.ᒹ᜜᯿SC.eᑺ.᳛70~80GyE.70%D.ßãäåÒᓄjᶭÍᑜÌÍC.᜜᯿S#wᐰᑺ.Ὶ49.¸¹ºᮤlᢣᵨ¹º½¾ᑁU.¿ᾙÁᙳ£WMNḄᮤFµE.ᨵçèé§ᱯ*ᙠpD.┐¢£¤¥¦§¨¢©ª54.êëìí10cmḄ&SὊï.᦮ᑺ.A.A᷈ÄᕜÅTD5/5E.òçᔜ⚗B.õ◞÷øA.3000cGy46.⚠!&ᶭL⌱%AஹBù*úᑺ.qC.(᷈*+ᕜ-ᡈ/◞B.4000cGyὃ*Fûᑖ¨øp12C.4500cGyA.A*øpü◖ç2§ÿ
D.45678᜜2cm;BᙠAᔣ᜜3cmD.5500cGyE.:B.
⚠᜜2cm,E.6000cGy2cmAᔣ᜜3cmB50.#$=ᶭ?@◀BB#$=ᶭ᜜CDᐹᜓGHḄJKLM55.#$TUឋOC.!
Ὶ#$%&'2cm,NO4

4A.WX=ៜឋ59.[-60r^_`ᘤXcdḄjkcl[-60efᜧḄhNiOB.#X=ៜឋE.$ᦣ$ḄjkA.[-60%vᜧvclC.WX=ៜឋoᨵᐵrᘤ$efᔣᦣ$ᜧ63.#ᶭᨬ☰4ᑺ~OD.^X=ៜឋsᐵB.[-60%vᜧvᘤ$efᔣᦣ$A.(᷈Ḅᨬᜧᑺ~E.^X=ៜឋᐵrtᜧC.[-60%vᜧvB.(᷈ᑮᨬᙠᑴ᳛Ḅᑺ~56.?ᵨv_`ᘤ^ᵯUD_`ᘤcᘤ$efᔣᦣ$dᐹᨵxyzOC.sḄᑺ~D.┐L60%vᜧvA.?ᵨv_`ᘤḄ{|ᑺ~ᘤ$efcᔣᦣ$D.ᑮ(᷈ᨬᜧᑴ᳛scᵯ¡¢£+¤Ḅᑺ~E.[-60%vᜧvB.?ᵨv_`ᘤḄ{|ᑺ~ᘤ$efcᔣᦣ$ᜧE.t¥¦Ὂ¨~Ḅ(cᵯ¡¢£+¤᷈ᨬᜧᑺ~60.JKᑺ~ª«hᑣiOC.?ᵨv_`ᘤḄ{|ᑺ~64.☰4ᑺ~Ḅ³ឋiᢣOcᵯ¡¢©+¤A.ᜐᳮ☰4^¯¨᯿ᑺ~ᐵrA.µ¶☰4±ᑺ~Ḅ·¸D.?ᵨv_`ᘤḄ{|ᑺ~cᵯ¡¢©+¤ᜧB.±☰4ஹB.☰4ᑁº»ᑺ~^☰4ᑺ¨᯿ᑺ~Ḅ᪗~±ᑺ~Ḅ©½E.?ᵨv_`ᘤḄ{|ᑺ~cᵯ¡¢©+¤C.³☰4ஹ=ᶭ4ஹC.☰4ᑁᨬᜧᑺ~^ᨬᑺ~᯿$4Ḅ-Èᑺ~ᜧḄ©½57.^X(r)cdÁ=ᶭᨵxyzOD.ÉÊ=ᶭᫀzÌḄD.☰4ᑁᑺ~±ᑺ~^☰4A.ᑺ~ᑖéoREBÅᜧOERÍᑁÎᑺ~Ḅ©½ÅE.ᵨϳ=ᶭᫀᡠE.☰4ᑁᑺ~±ᑺ~^☰B,ᑺ~ᑖãoREBÅOERÑᵨḄ᯿$ᢈÓ4ᑁᙳᑺ~Ḅ©½Å61.Ö¡ᵯ¡~×_ØO65.ᢥUICCäåæç▭ᑖé᪗êxëC.ᑺ~ᑖãoREBÅOERäåæḄ45678OÅA.ÙÚᑺ~DsxÜÝᡂ߸àßᵯ$·×ᜧA.ìῼ678+ïðñò678D.ᑺ~ᑖãoREBÅᜧOERÅB.ÙÚᑺ~DsxÜÝB.ìῼ678+ῳῚôᾭ67ᡂ߸à÷ᵯ$·×ᜧ8E.ᑺ~ᑖãoREB,OERÅ^X(r)ḄcöC.ÙÚᑺ~DsᓣÝC.ìῼ678+ïðñò678ᡂ߸àßᵯ$·×ᜧ^ῳῚôᾭ67858.ᵨÏöú¶=ᶭḄûT92#$%^ý737cdû-192ᙠḄᑺ~ᑖÃᐹᨵD.ÙÚᑺ~DsᓣÝᡂD.ìῼ678+┝ÿ
+ᵯᜧ
A.!"#$%&ᜧE.()ᑺ+Dsᓣ/E.
+0ῼ
23⊦5&6ᡂ8ᵯᜧB.!"#$%&:62.=>?SḄBCD=>?a66.ᙠGHIJKLᑖN3OIᓰ23⊦5&᠒XbḄTBCUᦔḄᱥᳮYZ[A.3ஹ4%C.ᙠ5ᔖceᑁ23⊦5ាA.C☢i/ᕜ>!lmnᦣ/ᡂ⊡q⍳s!"#UB.5t10%D.ᙠ5ᔖceᑁ23⊦5ាmB.C☢ilUC.10%wnᦣ/ᡂ⊡q8⍳s!"#C.C3xyzD.20%E.ᙠ5ᔖceᑁ23⊦5ᐸ|ஹᦣ|}~lUᢝ88⍳s!"#E.30%D.C3xyz|5

567.GHIᶭ⌕ᜫz72.O᷈Ḅ"ZB.10'15GyA.ᑁ
A.>ᙠOḄ᷈C.20GyB.B.O(ḄD.30GyC.⊈᷈E.40GyD.ᑁ᜜
C.O(᪵¢£Ḅ᷈ᐸᑁ¤ᨵ8¦ᦪ77.ញឋឋª«ªḄ¬®ᳮᦋE.᜜
D⊈+Ḅ
¢£[68.±GHI┝³
᳛D.OᑁḄ
A.⊈Hµᓄ·?¢£Ḅ᷈B.ញឋ¸¹ឋ«ºA.<10%E.O(¼᷈C.½¾ᓄB.10%73.ᵱឋ45ÀÁÂÃÄ0ῼᨵ4cmX5cmᙽÈɳD.«º+½¾ᓄC.30%ÊËᙳÍ┛ᓄDᕜ□ᘤÑᨵᾦÓ|ᑖÔᨬÖ×ḄØÙ?E.⊈Hµᓄ+ª½¾ᓄD.50%A.ᵬÛO᷈78.ܪ:¢£ÝᑖᓄIªᨵÜÞE.50%wß3cmᙽª0ῼà┝³
B.O᷈ãäᜧåæᑖçè69.$%GHIᶭᶭᦔḄâ[C.ᶚêN᷈A.▲A.®>D.
᷈B.T2N2M0B.X|®ᳮᑖìE.xᒹóC.T3N3M0C.ðñ74.ôÄõIஹH:¢£ªID.T2N3M1D.ᨵÍ┝³
øSCLCúᶭzᑣ[E.üýE.wᐰ[A.ÿ+ᓄᶭ79.᷈Ḅ⌕☠70.UICC▭ᑖ᪗!⚠#B.ᓄᶭ+%ᶭ+ᓄᶭḄ&'()*ᒹ,-A./0123C.ᓄᶭA.⚠4+┝67()*B.@ABC23D.ᓫ:%ᶭ+ᾯ⚜■᯿?B.⚠4+Dῼ()*C.HIJ2E.ᓫ:G+ᾯ⚜■᯿C.⚠4+7Dῼ()*?D.K4XM23D.┝67()*75.ញឋ%?ឋQRᙠ%ᶭE.YZ[23ᑁ!UᦪWXᙠ%ᶭE.┝67+Dῼ+\]()*ᑁ80.%ᶭᜫ`abc71.aWDῼeaAB᷈%ᶭḄgA.3iᨴ!6iᨴA.lm4ᜫ`n⊈pᔜr-
50%,s⊈pᓰ80%v7B.1iᨴ!3iᨴA.wxB.l⊈pᓰ80%,smC.3iᨴ!3iᨴ4n{ᜐᜫ`ᓰ50$B.᷈x+z┝67&%ᶭD.~iᨴ!3iᨴC.lm4ᜫ`U{ᜐC.ᐰDῼ%ᶭᜫ`!sᑣE.3iᨴ!3iᨴD.᷈x+ᐰDῼ+z┝67&%ᶭD.lns✌ᜫ`Y76ᐰ%ᶭᨬᜧᑺE.K4!z┝67&%E.lnsm4n{ᜐᶭᜫ`ᔜᓰ50A.10Gy6

681.ᜮ⚠4⌱ᵨᓫ:%ᶭ〉ᵨ86.᝕ឋ!65!᜜▢l,▢™¡ᱥ3X3X3cm3,¥¦J§¨90.©⚠ª᜜᯿?ᒹ,Ḅ()*&'A.«☘ὅ•!°±²⌕³´µὅ▲!·⍝¨¹º1cm!»%ᶭᑺ-ñ-B.᝕ឋὅA.56ஹᘤᑁ᜛:ஹ;<ஹῳ>?A.<10Gy/lᕜᑁᾭABῳCDEFGC.°G¼½B.l(T20Gy/ø2ᕜB.56ஹ;ᑁ᜜ஹῳCDHஹID.¾ᳮÀᑖᓄÁḄJ;?ᾭAD.50~60Gy/5ù6ᕜEFG82.Çȵᑺ᳛ÊËᶭÌÍᘤÏÊE.>60Gy/6ᕜD.MῚEFGஹ‒EFGஹ>?ᾭAEFGA,ÐÑÒ☰&87.üὅ!25!▢⍝ý71/3þAB!ÿᑖIE.;<ஹῳ>?ᾭAEFGB.ÑÒ☰&!ÔÐᙠÕ?ᑺὅᶭ⌱Ö×´Øᚆ#ᑁ91.O⚠QRS)mUᔠᳮḄ2ᶭA.᜜᯿C.Ú᯿?&nÛÜ&ÝÞA.᪷2ឋ[B.▢⍝Ὶᑁ᯿D.Ð{ß☰&B.᪷2ឋ[ὶᔠᓄᶭC.᜜Ὶᑁ᯿E.àὃ⇋%Ú4ZC.ᓫ_▢⍝ᑁ᯿D.᜜!"#᯿83.ãä&ᗕ%ᶭ⌱ᵨ?MḄᨬæD.ᐰMῚ"aᢱc᜜᯿ῚᑁcE.᜜᯿%&'Ὶ᯿ᑁ᯿A.ç4XME.ᓫ_᜜᯿88.▢⍝)*᷈,-.1/32B.Co-60rMᡈ4MVîMïðᘤXᶭ3ᑣ92.efghiḄh%O⚠)ᶭjkwxyA.stO⚠)2ᶭC.8~10MVpkqᘤXk3ᑣuvA.᯿z{Ḅ⌱s|ᔠD.>10MVpkqᘤXkB.>⌕┐▢⍝*᷈B.᯿ᑺ¡Ὶᑁ᯿E.ᵯtC.Ὶᑁ᯿j½¾¿'ÀÁC.>⌕¡ᐰMῚ᜜ῴÃஹpÄ84..)Ḅ⚜᯿D.Å▢⍝®A.ẚD.᜜᯿wᒹ£ῳCDEFG¤E.ᒹ£'.ᔜ⚗B.ᑁẚE.᜜᯿wᒹ£ῳ>93.O⚠)᪷22ᶭḄᢣÈC.ẚ?ᾭAEFG¤A.MῚEFG□ឋD.ẚ89.O⚠)2ᶭ¥ᑡ§⚗┯ªḄB.ᑗËÌE.ᑁ+ẚA.«ᢝ▢⍝®C.*᷈ÍBO⚠HÎÏ85.⚝᷈h-B.¯°±D.[ᑗËᐙᑖA..C.°±j²᪷³´µ¶E.ᒹ£'.ᔜ⚗B.≈¯ᔲ⊡ᐙ2ᶭ94.tOᑁÐ)Ḅᶭ'¥§ÑÒC.D.᝞»2ᶭGjᦔ»Óײ1Ø°ÙD.ÔᚁA.ᶭḄèḄᙠ-éê*E.᜜ᙢὅ²ᙠ▬ÝÞ᷈ëìef°hஹ᡽ᦣḄïðE.Ö▾ᢥ⌕áâ±ãG»äå32ᶭᓫ,æ᫏B.ñòóḄὅᙳw¡7

7ᶭ99.LETḄ¯øC.2ᶭ+ᢙúûü■þC.±ÿᑁ
ᳮG3ὅA.ᓫD.ᶭ+ᢙ⏘!ᡈ#$Ὶᑁ&ᶭ⌴()*+D.II-.ὅ$&ᶭB.⌴E.&ᶭ+ᢙ⏘!ᡈ#()*1E.MRIᡈCT6789:;Ḅ.ὅC.=⌴>ᐵ$&ᶭ104.CᜧEFGHIῼK᷈MNKHD.=\]^ᱥᦔaᨵᐵ᳛ᓰGHIῼK᷈Ḅd95.QᨵSTᔠVWXYZᓫ[&ᶭḄII-eᑁ
f.ὅgῚᑁ᯿iFkMAkḄE.=rsᔠᨵᐵA.60%ᑺmn⚗pᔠ〉d100.ᢥ87yUICC{|fᑖ-᪗B.6080%A.3d2g{|ḄdC.70%B.2d3A.ᾭD.80^90%C.1d1B.ᐭ|ᑖE.50^70%D.2d1105.fḄ:E.1d2C.ᐭᾭA.H^¦|§Ḅf96.ᐵᓿfḄᐰῳ᯿ig£☢n⚗¥¨©dD.ᑗ|B.H^«¦|§ḄfᑖA.〉¬-®ḄᓿfC.H^¦|fE.ᾭ|B.᯿ig¯°±ῼg£ᑖD.H^´µḄf¯²³101.{|ᐭ\¶§£n·⚠E.H^|¦|µḄfC.¹º»ஹ¹᫱¾⌕VHWÀd106.Passocose᷈ÇÈfÉḄdD.ÊËÌូஹᕏᔢÐញឋ&A.ÓÔ⚠ÀiÕaA.ῚᐭÖg;×ᕜÙB.ÓÚ⚠ÀÛg⌼ᡂᒓßàágâ;⇨gHorner'sE.YZDT2530Gy,68ᕜêᡂëg$ìíîáÐWïC.ÓC⚠À97.ðfñòóᮤḄ᯿iᑺÇ⚜■ឋB.ῚᐭÖg÷ᨵ᯿iᡈø⌱úឋ᯿iÉdD.Óû⚠ÀHorner'së=Ὶ☟ᾭýþÿᔠ
A.70GyE.⚠C.,ῚᐭᨵHorner's
B.60Gy102.%ῼ'᷈Ḅ✌⌱,ᶭ./01D.Ὶᐭᨵ34C.50Gy8ẚ:A.67,ᶭD.40GyE.Ὶᐭᨵ<=>B.@A6ᶭ+.@CDE
E.30GyC..@,ᶭ107.FGHIᑖᓄLᓄ6ᶭMᶭᦔ98.QRS,ᶭᶭᦔᨬUḄ01VWXCR,Z[2\]^ὅᾯabcZ᳛D.@Aᓄᶭ+.@%1A.LE.ᓄᶭA.50%B.fgL103.hijklḄm᷈,B.40%C.n⍝Lᶭ✌⌱X1C.80%D.pq⚠LA..@,ᶭD.40^50%E.stLB.67,ᶭE.30%8

8A.⚔yzab᳛1108.uFGHLᓫw6ᶭḄ5\Z[᳛01B.MyA.{|A.<2%C.◚B.|B.5^10%D.AyC.LC.20%E.yD.{D.30%114.L^⚠zabE.⚠ஹ┝4^0ᔲ⚜■᯿7¼E.40%119.ÉÊLḄ,ᶭ®ᐜÌᵨ1A.◤⌕109.ᜮ⚠'᷈6ᶭm'A.᪷,ឋ6ᶭc1B.§§B.᪷,ឋ.@,ᶭA.u6ᶭᱯᜐᳮC.᯿720¿30GyÀÁC.ᓄᶭB.£]¤¥ᜐᳮᓽ§D.®Â£ÁÃḄ⚜■ᑺ¶D.6ᶭ+.@Ïᔠ,ᶭC.£ᦱ,ᶭᓽ§E.®Â£᪷,ᑺ¶E..@+ᓄᶭD.◀Ὶª«¬Z᜜®£ᐰ°ᢙ²³ᨚ6ᶭ115.ÆLÇÈḄ⚠120.LÇÈḄᳮÐÑ1zabḄæ01110.LAÒ⚝>CÔÕÇÖ×1A.íLA.⚠^çzÒA.ῚÔØB.î^ïLB.⚠ஹçzÒB.ÙÚÔØC.IᑖᓄLmLC.èzÒC.ÛḸÔØD.mLD.éê>CëÒD.ÝÞ◣ÔØE.míLE.┝4^zÒE.⚝ᑁÔØ121.L⚠zabUcæ1116.Ḅូឋ᷈ḄUc111.Horner's
0ᢣâã>Cäå1æ01A.èÒA.WA.ðñB.⚠ç^ÒB.VB.yC.⚠çᡈ⚠çஹ^ÒC.VIC.ó᪷D.⚠çÒD.VIID.ᡡ᪻8öE.┝4^ÒE.÷ø>CE.ñù122.ÉÊL•ûᨵ⚠zab(T1N1MO)RᶭTᫀVὃ⇋112.L,ᶭüᵨ⚝ýþ⌕ᵨÿ117.ᡡ᪻/ᨬ12Ḅ4ᳮ6&A.Zᮤ\⚠JK]᪷Rឋ_A.⚝⊡ᵨឋC.Zᮤ᪷Rឋbᶭஹ⚠JK]D.Ὶஹ᷈ᶇ⊡ᵨbᶭᡈbᶭ+_`D.@ABCE.⊡ᵨD.Zᮤ_`c⚠JK]᪷RឋE.DᑖᓄEbᶭ113.ᡈ!"118.FGᡡ᪻/HḄ⚠JKE.Zᮤ\⚠JK]᪷Rឋb9

9ᶭD.᷈/ᕜB.ÃÄᓄᶭ+bᶭ+_`◞G123.᪷RឋbfRᶭgḄ᯿fiC.`Åbᶭ+_`E.ᓫ☢GA.j◤᯿fZHD._`+`bᶭ128.Ὶᨬ124ᳮ6&¢B.Z+lmJK]noHE._`+ᓄᶭA.DᑖᓄEC.ZH+Bஹpஹg⚠JKn133.⚝t᷈bfᑺÆÇᑴᙠoHB.8ᑖᓄEA.35GyD.Bqcgq⚠rstᐭ+C.7Bp⚠JKnoHB.40GyD.DᑖᓄE\£¤7E.Bqcgq⚠rstᐭᩭGḄC.40~50Gy+Bஹpஹg⚠v┝BJKnoHE.<ᑖᓄD.50´60Gy124.ᗕḄz⌕|4}~129.§¨©!E(T1N0)E.>70GyA.\⍡ᨵᐵ᜜᯿f«¬RᶭcZᮤ\⚠!᜜᯿fᑺ¯°134.Ì1ᾯάbᶭḄὊТ:B.\ᨵᐵA.1500cGyA.30GyC.\ᨵᐵB.2000cGyB.40GyD.\ᔾᨵᐵC.3000cGyC.50GyE.\sᨵᐵD.4000´5000cGyD.60Gy125.BHT1N0M0ḄRᶭ_r⌱ᵨE.7000cGyE.70GyA.ᓫ_`130.Bµ¶·Flᑖº»ᔠᳮ135.ᚖ/Ó7᷈¢ᢣB.ᓫbᶭḄ¢A.<5mmḄ᷈C.bᶭ+_`A.<180cGyB.ClOmmḄ᷈D._`+bᶭB.180cGyC.<15mmḄ᷈E.bᶭ+ᓄᶭ+_`C.200cGyD.<20mmḄ᷈126.Hᗕ(T1N0)ḄRᶭ⌱D.240cGyE.<25mmḄ᷈E.260cGyA.ᓫbᶭ136.ᾯÖ×᷈pᨬ12Ḅ6&¢131.Bµ¶Ḅ¾¿⊤Áᨬ12B.ᑗ◀ÂA.ØÙÚÛ᷈C.ᐰᗕᑗ◀A.ÝÞ;BµᱥB.àáÖ×᷈D.bᶭ+_`ᑗ◀B.âஹãäC.åtæ᷈E._`+`bᶭC.☢!ç;èéD.ÙឋÖ×êÚÛ᷈127.§¨©!E¬ìíḄîD.Bᱛÿ
ὡE./012᷈ëE.Ὶ
137.4567ᨬ9Ḅូឋ<᷈'A.᷈/pïëðñGᘤᓽVᔾ⊈A.ᾭ>?᷈B.ÌTÙ᣸ᑡ132.ḄḄᔠ!ᶭ#$U&'B.@A᷈C.ᢥ☰HùúᵨKûüýGA.)ᶭ+ᓄᶭC./012᷈1()

10D.ᾯ?᷈DB.50%E.⊈HIJ12᷈D.ᓫLM᜜᯿DC.60%138.QRMSTU12᷈Ḅ᯿DVWX'E.M᜜YZ[᯿DDT70Gy`aD.70%A.bcdV143.f⚠hiῚᑁ!ᶭkl'E.90%B.bc᡽ᜧVA.pᑺr᳛Ὶᑁ᯿D4.ᙠu᜻wx◤z{⚜■᯿Dx~{⚜C.ᐰᾯ᯿D■᯿Dᑺr'B.ᑺr᳛Ὶᑁ᯿DD.ᐰᾯ+⚠/A.1200cGyC.pᑺr᳛᯿DE.ᐰᾯᓝᐰ/᯿DB.1650cGyD.Zᑺr᳛᯿D139.᜜▢ᓫL)ᶭḄ〉&'C.3000cGyE.Zᑺr᳛᯿DA.xD.2500cGy144.f⚠)DḄB.ὅὁM'E.2000cGyC.ὅA.Dᢙ5.1AஹIIAu᜻wx£ᵨᐰ¥¦᯿DḄxᳮ®'D.§ᨵ©ªḄᔠ«B.DpA.¥¦12´®µᔠ12®E.¯ᙳ±&C.D²³B.¥¦12⊦º®µᔠ12®140.᝕ឋ,70,᜜▢¸II,ᔠ«D.»[xz᜜▢᪷!½¾¿ῳÁÂ¥C.¥¦12´®¥¦12⊦¦ÃÄÅÆÇz'º®A.Æᓄᶭ)D!ᶭ⚪É1999D.¥¦12´®Ã⁚Ëᓄ®B.Æ)ᶭ1.ᙠu᜻wxḄxᳮÌÍZ'E.¥¦12⊦º®Ã⁚Ëᓄ®C.ÎÏ!ᶭA.R'S12ᨵÌÍÓÔÕ±&6.ᙠÖ×u᜻w¥¦᷈ḄØῳ)ᶭ<᷈12ZÙ▤!ᶭZḄ¿V᯿Dᐸ´⌕ḄD.)ᶭ+ᓄᶭ&'B.R'S12<᷈12E.▾ÞßA.àá/C.R'S12åឋ12141.᜜▢)ᶭÆᨬâãäB.àáæç)ᶭÆ'D.¥¦12<᷈12C.⚜■᯿DaìA.1è2ᕜE.êë12<᷈12D.ðpÖḄ᯿DᑺrB.2~4ᕜ2.ᨚãឋ)Dឋᨵ/ïᨵJ•òóᙠ)ᶭÆḄ'E.ðpdôḄ᯿DᑺrC.5è6ᕜA.õöᨴ¯ᑁ7.T¥¦012¥¦᷈#øl'D.8ᕜB.2è3öᨴA.⚠c¥¦ÃE.12ᕜC.3è6öᨴB.ῳ?Æ¥¦Ã142.▢⍝ᑖᓄ¸in⌱þ)D!ᶭ᯿Dÿ
D.6ᨴC.ῚA.ῚῳE.2D.ῼ᜜᯿!"▢⍝%ῚῚᑁ᯿!3.(᜻*+✌-./
0⊤E.ῳB.ᓫ4▢⍝Ὶᑁ᯿!5-67⚠9ὅ;<8.ូឋ᷈ḄEFᑖHᢣC.Ὶ᜜᯿!"▢⍝Ὶᑁ᯿A.45%11

11A.J+ᳮLM5NOPEF.E.50R55GyA.ᑖH/ஹVWXḄᑖHB.+ᳮᑖgB.J+ᳮLM5OPEF./ஹVYZ[\WXḄᑖH13.^_`!aᶭc5dḄὊfC.h☟ᾭfkᑺn
C.+ᳮLMlW5OPEF.D.hofk/ஹVWXḄᑖHA.25GyE.fkD.+ᳮLMlW5OPEF./ஹB.35GyVYZ[\WXḄᑖH18.᪷Pq᷈`!aᶭrḄst5᜜᪷C.60Gyaឋ`ᶭuᵨ7ῴxyEFE.+ᳮLMlW5OPῳ9z᩵|WXḄᑖHD.45GyA.T1T2H9.d-(᜻*᷈`ᶭḄ5E.55GyB.T2T3H6᳛
14.-ឋyᙠᑡC.T2HA.45%uὃ⇋`ᶭD.T3HB.50%A.5ᨵஹῳE.T4HC.55%B.ᨵḄ19.ῴxyḄ+ᳮ¡⚜Ḅᐵ¤D.65%¦ᨵ§ᓄA.°y±7²³´yE.75%C.q᷈©7ª«5¬«®¯ῳB.µy±7²³´y10.¶·¸(᜻*᷈Ḅ^¹+ᳮº»¼D.½.»yC.µy¾°y⚜¿ÀA.᜜ᕜT³´»E.ᨵ᜜²D.°y¾µy⚜¿B.Tó´»15.ĵyḄ`ᶭc5Å7ᕜÆᨵE.+ᳮº»¡⚜JlÇḄᐵ×Ø`!ÙÚḄÛᘤ5☰Þ¤C.B³´»▲ᑴᙠ____cm3ᑁ20.ῴxyã^¹Ḅ+ᳮº»¼D.BÈÉó´»A.800A.ូឋäᜮ/᷈E.Burkitt᷈B.1000B.²æy11.Ï▲7ÑῚḄ(᜻*᷈ᑖC.3000H
IE,`!ÔÕÖ
C.äᜮ/yD.2500A.“è”êÔ᯿!D.µyE.1800B.☢⚠ὶᔠÔ᯿!E.°y16.ðñyÏ96ò⊤ó
¸ôC.“è”êÔ+⚠9⚜■ñõ⅁÷Ḅøᔣ5ú÷Ḅû21.▢üy▢ü+ᮤḄ᯿!5þ^⌱ᵨ

D.“L”᯿A.XA.5cmE.“L”+⚠⚜■B.C0-60r■B.4cm12.()᜻+,-᷈Ḅ᪷1᯿ᑺ34
C.6Xᡈᵯ9C.3cmA.25:30GyD.X>6XD.1cmB.30:35GyE.CO-60r>ᵯ9E.2cmC.35-40Gy22.@AB4CᙠEFGH᷈I
17.LMNOPQRSḄ⚜TD.60'70GyUᐵ
A.WXYᨵ⊈\HCGᓣ12

12B.WXYᨵ⊈\AFPᓣE.ª°±>²ᙢ´µD.T2NoMoC.ᨵ50%ḄbcYᨵHCGᓣ27.1987ÀUICCSḄᑖjE.IVjD.ᨵ50%ḄbcYᨵAFPᓣICwx┝,-v´µÄ
31.ÆÇÈÉÊᾙ᷈Ḅ¬ᶭÌ┐o
E.⊈\AFPஹHCGQbᳮhUiA.N2dᐵeA.ÎÆÏÐB.N323.HAHBjEFGH᷈Ḅkᶭno:B.ªᑗ◀+kᶭC.MlA.ῳrsᾭu,-v+wxy⊈C.᡽ᜧᑗ◀Ðz,-v+{ῼ,-v}D.I1IAjD.᡽ᜧᑗ◀Ð+kᶭB.ῳrsᾭu,-v+wx~⊈E.IHBjz,-v+{ῼ,-v}+┝}E.ᓫÚ±¬ᶭ28.SÖ×T2bØ,⌕¬C.ῳrsᾭu,-v+wx⊈ÏÐTCL@MÛÜPÝWÞᑁ32.ᙠÈÉÊᾙ᷈ḄÏÐTkᶭICß᷈z,-v+ῳ-v}}᯿
ᜧà10cmὅCkXáß᷈âã᜜k
D.ῳrsᾭu,-v+wx⊈A.bØ¥à᜜å▲CᨵA.3cmz,-v@çèé,-v´µB.4cmE.ῳrsᾭu,-v+{ῼ,-B.bØ¥àᑁå▲Cv}bᳮ4êzᑁSC.6cm24.ᙠᑡSḄICᨬᨵC.bØ¥àIë}CìD.8cmḄ⊈\ᢣ᪗o
íSUèé,-v´µE.10cmA.⏚ឋ⏚⏘D.bØ¥àIë}CìíSᨵèé,-v´µ33.LîbᳮhḄÈÉÊᾙ᷈᧕±ð,B.ឋ⏚⏘-v´µ
E.bØ¥àᑁ©å▲CC.ᑡᱯឋᢙFìíSUèé,-v´µA.ñòᾙ᷈ஹóôõᾙ᷈D.⏚ឋ⏚⏘>ᑡᱯឋᢙ29.@SὅCF±ᮤ2X2cmB.ូឋñòÉÊGH᷈ஹᾦùᾙF¥à᜜å▲Cß᷈ᑗ◀+èé᷈\úÐCß᷈ᑗã▢ឋCÐTE.ᑡᱯឋᢙF>ឋ4T2N0M0,ÐTkᶭḄnXC.ñòᾙ᷈ஹôþᾙ᷈⏚⏘ᒹý
D.ᾙ᷈ஹᾦᾙ᷈25.Sὅᑁ}᯿¡CᑁA.ᐰ
+ᑁ¢ὃ¤Ḅ¥¦4
E.ᾙ᷈ஹᾙ᷈B.ᐰ
+ᑁ┝A.Iu3cm,¨©2cm34."#$%&'()*T1N0/⚠%Ḅᜐᳮ:B.Iu3cm,¨©3cmC.ᐰ
+ᑁஹஹ┝A.4◤ᜐᳮC.Iu4cm,¨©2cmD.ᓫ7ᐰ
᯿9B.⚜■ឋ⚠%=ᶭD.Iu3cm,¨©4cmE.ᐰ
+C.⚜■ឋ⚠?◀AE.Iu4cm,¨©3cm᯿9D.⚠LMJNIO=ᶭᡈQA26.ª«jS¬ᶭᜫ®Ḅr⌕FN30.BCὅᙠᐸGᑁHIJKo
RSTUᑖWX1.5cm3cm)ឋE.⚜■ឋᐰ⚠=ᶭ\ᮤ^_LM`aᙢLMcA.ª°±ᑖ'Xd35.efghᶭᐹᨵkLETḄdB.²ᙢ´µA.T3NoMoA.ᱥᳮᱯqcBragguC.}¶,-v´µB.T4NoMoB.NᱥᱯqD.b·WὊ¹¬ᶭC.T1+T2NoMoC.ᐹᨵᱥᳮ`Nᱥᱯq13

13wᐰxᓄᶭzᔠῚᑁ=ᶭD.^}ᱯq40.᝕ឋc50cJKῼ᷈QA᷈44.ᨵᐵ⚠)=9hᶭḄc⚗E.LEThᶭB᪵ῼᒹ3cm,᦮┯Ḅdᑗ◀᷈+%ᑖᒹᑗ◀cA®\36.¡¢ᨬᜧᑺ¦§*TMR/4©ª«¬ᳮX“°
᷈c«±²X³´”A.᩽&'Cὅ*0'ஹla'/¸¹ᓄḄº»d¼B½Ḅhᶭ¾ᫀdÀÁῚᑁ᯿9A.ÂSSD¹ᓄIcd/SAD4¹A.ᑗÆÇ©ÈcÉJB.BÊËcÌÍ᜜᯿9ῚᑁIOÏ=ᶭ᯿9ÐᔠB.ÂSSD¹ᓄIc9Ñ☢Ó4¹B.A®ᓄᶭC.᜜᯿9¸᪷ÕᐹÖ×cØC.ÂSSD¹ᓄIcº9ÙÚÛ4Ñ᯿9ÜÝ•ßḄᑺ¦¹C.A®᷈à᪷hឋ=ᶭD.ᓫ7Ὶᑁhᶭ.c¸â᷈ã%D.ÂSSD¹ᓄIcᦣ9ÙÚÛ4¹D.A®ÏᐰᒹᐰäkåæᑮhៜḄéḄῼ=ᶭ+᷈àÜÝᑺ¦=ᶭE.ÂSSD¹ᓄIcSAD4¹E.᜜᯿9êῚëᑺ¦4ìíE.A®=ᶭ+ᓄᶭîDT50Gy,ᔲᑣzJó¸ôõöÝ37.ᑨù¼úûüýþd41.ᵱឋ
45
45.⚠ᶭAஹB⊤ḄᶭA.ᑺᑺ!☰ᑺ#᪶
%&'(ᢙ#᪶ᶭ
ᨬᑖ,-.34ᱏ678ᮤ:;<=>?ᜧB.ᑺ/ὃ1ᜐᑺ!☰ᜐᡂBᙽD
EFGᝰᶧ!.A.⚠J᷈ᑺஹLMᑺNᑺA.#᪶ូᓄB.⚠J᷈ᑺஹQRST#C.ᑺ(Vᑺ!ᑺ/ὃWᑺ1ᑺB.#᪶ᳫC.^_`ᑺஹQRSTD.ᑺᑺ!☰ᜐNᑺC.#᪶ᔠ[\]LMᑺD.#᪶abcᓄD.^J᷈ᑺஹ^J᷈#⁚E.☰ᑺ!☰ᜐNᑺᑺE.qr38.ᵱឋ
75,ᨵ▰kឋlm᫱opE.⚠J᷈ᑺஹLῚST#ᑺtJu
v⍝⌼yᱏz4{|v}ᨵ4cm42.Ḩ-ᢣ⚝ᐙ
₝
G᫱
ᨬNᫀ!..46.⚠=Ib2
ា¡ḄᶭA.ᶭA.IIஹIIIஹIVஹVN¢!.B.ᶭ+B.IIIஹIVஹVஹVIஹVHA.¥ᶭC.ᓄᶭC.IIஹIIIஹIVஹVஹVIB.¦§ឋᶭD.+aᶭD.IIஹIIIஹNஹVIஹVIC.ᶭஹ¦§ឋᐰªᑗ◀E.᪷ឋᶭE.IIஹIIIஹVIஹVID.ᶭஹ¦§ឋᐰªᑗ◀·LῚST#¸¹39.ᵱឋ
45
<¯ῼJ᷈±²³43.▢⍝µᑖᓄ¶IH
ᶭ
º᦮ᑗ◀J᷈pJᜧḄST#
¼ᑣ!.E.ᓄᶭஹ¦§ឋᐰªᑗ◀a8ᳮ!“À¼᷈ÁᨵÂST#[EÃᓿÅÆÇ
ῳÉCTËÌ,ÎÏ'Ð
ᶭNᫀA.ÑᐰÒᓄᶭ!Ó
Ô
:Ñᶭ47.⚠Ö×Ḅ¥ᶭ¼ᑣ.A.ᐰ¯ῼ+Ø┝Ú{ᶭB.Ñ¥ᶭ!Ó
ÔA.pÛ⚠Ḅ¥ᶭ¼ÑᓄᶭᑣÜÝB.aᓄᶭC.ÑWᓄᶭ!Ó
ÔB.ÛÞᵨᐰLᢱá᜜᯿¥C,ᐰ¯ῼ+Ø┝Ú{ᶭ+ᓄÑᶭ·Ὶᑁ᯿¥ᶭD.ᐰÒᓄᶭåWᓄᶭ
C.æçèéêëஹῴíîïFD.ðÉᶭ+ᓄᶭÔÑᶭD.ῚᑁᶭöᐙᑖᛋoøVE.ñᑗòópVô᩵E.ÑWᓄᶭ!Ó
Ô14

14E.Ñ{ᙳ⌕ὃ⇋F
ÚüýþÿᔾᦈᔣᦣC.᡽ᜧᨵᵨ᯿±Ḅ48.⚠ᶭḄឋ³D.µ¶·ÎÚÛᑺ(_Ü✌ᐜὃ⇋Ḅ"#$%ÝᔾᦈᔣᦣᜧD.´ᜧX§Ḅµ¶ª·A.'(ᶭE.µ¶·ÎÚÛᑺ(kÜE.'kX§Ḅ¸ᑺ(ÝᔾᦈᔣᦣB.ᨚ+ᶭ53.s¤ᘤX§Ḅ¹ᘤḄº»56.2Þßà¾SADÁ᯿ᢈãjäÑC.-.ஹ01234ᜐᳮᨵ%ÍÚc¾SSDÁ᯿ᢈãRÇᐸᱯË$%D.89:⁚<=A.3¼¹ᘤஹ½3¼A.SADᢈãåæÓÔå羿ÀÁ¹ᘤºèéàḄÓÔÇᜧE.?ᑗABB.3¼¹ᘤஹ½3¼B.SADᢈãåæÓÔåç49.ᙠE᷈G▾IᶭḄូឋE᷈KL¾¿ÀÁ¹ᘤஹ¢Ã¹ᘤÄèéàḄÓÔêÇᨵNOPᑖRḄKLSTIᶭ%ºC.SADᢈãåæÓÔᜧåçA.80%—90%C.3¼¹ᘤஹ½3¼èéàḄÓÔǾ¿ÀÁ¹ᘤஹNŹᘤÄB.65%~75%ºD.SADᢈãåæÓÔᜧåçèéàḄÓÔÇᜧC.50%—55%D.3¼¹ᘤஹ¢Ã¹ᘤஹNŹᘤĺE.SADᢈã᧕n᤮æD.40%—50%E.½3¼¾¿ÀÁ¹57.íX¾rÁ§ª(´se:E.30%—40%ᘤஹ¢Ã¹ᘤஹNŹᘤĺA.ÚÛᑺ(DsᓣðᡂòÏó50.]ᵨ_ᑺ(᳛bcdIᶭE᷈e,ᐸòòÏᑺ(´shᑺ(i%54.᜜᯿jᑁbcd᯿RÇᐹᨵÈÉᱯË%B.ÚÛᑺ(DsÈôðᡂòÏóA,jkᑺ(᳛bcdIᶭl᪵õòÏᑺ(´sA.IᶭcdÌÍB._nkᑺ(᳛bcdIᶭÎÏkcdÐzRÑÒÓÔC.ÚÛᑺ(DsÈôðᡂòÏóᜧᜧòòÏᑺ(´sC.knkᑺ(᳛bcdIᶭB.IᶭcdÌÍD.ÚÛᑺ(DsᓣðᡂòÏóD,o᯿᜜᯿ᑺ(ÎÏ_cdÐzRÑÒÓÔõòÏᑺ(´sᜧᜧE.jo᯿᜜᯿ᑺ(rsE.ÚÛᑺ(DsóðᡂòÏóC.IᶭcdÌÍòòÏᑺ(´s51.uvE᷈Iᶭwxᵨᑖy᯿ḄÎÏ_cdÐzRÑÒÓÔz{|}:ᜧ58.☰÷ᑺ(±5%ùúឋi᪷%A.lyᜧᑺ(᯿ᡠ◤Ḅᑺ(D.IᶭcdÌÍÎA.E᷈ᑺ(Ôû§úÑÏ_cdÐzRÑÒÓÔᜧ,ḄB.ly᯿ᜧB.ᑺ(Ôû§úÑE.IᶭcdÌÍḄC.ᑖy᯿ᵨᜧḄhᑺ(ÎÏ_cdÐzRÑÒÓÔᙢᩔE᷈C.E᷈Ḅü«ýᑴÿ᳛ḄᑺᢣᦪḄD.ᑖy᯿᪷KLᐹ55.Õl60r§j200KV—400KV—Xe:᦮Iᶭzᫀ§RᐸÙË$%D.Ḅ᳛ḄᑺᢣᦪḄE.E᷈ḄᨵᑭnA.µ¶·ÎÚÛᑺ(Ḅ¡¢kÜÝᔾᦈᔣE.᷈Ḅᑴ᳛ᦣᜧḄ᳛Ḅᑺᢣᦪ52.Gᵨs¤ᘤxᵨX§ᙳ᦮ᘤḄuḄḄi%B.µ¶·ÎÚÛᑺ(kÜÝᔾᦈᔣ59.ᙠ!X#ᑖ%&'()ᶭ+,Ḅ-A.©X§Ḅkª«ᑖᦣ%./+,-%._:B.ᦋᗐX§Ḅª®ᑖ¯C.µ¶·ÎÚÛᑺ(A.₝4%5Ὶᑁ%'89%15

15;<=>?@'ᑁABC/D'EῼGHᜧJKL'MNᜐPQ'ᢥ87B.Ⅴ4%5Ὶᑁ%'WX%YZJKLᜧ'[\.3cm,ᨬbUICCᑖf.ghiḄjklgC.WX%5Ὶᑁ%'89%A.T3N2M0A.YmnD.89%5t4%'Ὶᑁ%B.T3N1M0B.YᾱvE.wv%5x4%'WX%C.T4N1M0C.yzឋYL᪶60.ᵱឋ'50'jk.“!n”'D.T2X2M0.5cm,CTHM᜜D.YnNᜐPQ'ᨬᶭᫀ.gE.T4N2M0E.YPQ᷈A.᪷ឋ)ᶭ69.◣ᑁ¡Ḅ⚝£¤lg65.CTY[\2cmB.¥¦ᶭḄL⁚'¨©ª«¬®8A.nஹm⚝£¤¯°'YZ±EῼJKLᜧ'C.ᓄᶭ+)ᶭ[\2cm,¶·¬Ὶ¸¹º»¬¼B.IIIஹIV⚝£¤.⊈ឋ'¾¿ÀÁÂ(-)ឋ'D.)ᶭ+Ὶᑁ)ᶭᢥUICCᑖf.gC.IVஹV⚝£¤E.ᓄᶭ+¥¦A.T4N2M0D.V3⚝£¤61.&!n'.5—8cm,MB.T3N3M0E.VI⚝£¤ÈÉ'Êὅ/ÌÍ¥¦'ᨬ᯿ÏÐÑÒ.gC.T3N2M070.nÓfÔÕḄÖlgA.Ð5×ØÙÐD.T4N2M0A.ᛋ'Û'☢ÝÞB.×ÙÐE.T4N2M1B.⊈ß'ὡá'ᜮÞC.ØÐ+ãØÐ66.(ähåæç!YḄᑖèᱥC.ᛋ'☢'êë&ÂHn¾¿'ìíᨵnïᙠ'D.ãØÙÐðXᐝᱏæç!óGHᮤõ'D.ùú'ûü'ý⊈ᙠYnTNMᑖf&ö÷øgE.ãØÙÐE.ᜮÞ'ᜮ᧿'·ÿ
ᩈA.T162.ᵱឋὅ᠒ឋ71.᷈Ḅᱯ!"#ᶭ%&'()*ᨵ,B.T2/,123A.,!᳛89:ឋ;1B.,!᳛89ូឋ;

16B.40-50Gy/4-5ᕜA.ᓫ¥C.ᢙpkᶭஹ▢⍝ÈÉC.30-40GY/3-4ᕜB.ᓫ¥#ᶭD.Ë◀Í⚠£ᜧḄ᷈]ÏD.20-30Gy/2-3ᕜÐ#ᶭÑ⌼ᩩÔC.ᓫ¥ᓄᶭE.10-20Gy/l-2ᕜE.ᒹ×9lᔜ⚗D.#ᶭ+Ãᔠkᶭ79.▢⍝Û±l1/3ÜÝÞß83.Í⚠ÜÝÞ߸ᙽàáâIb2E.ᓄᶭ+Ãᔠkᶭáâᑖe]IeាåḄkᶭ]e#ᶭæçᵨ74.é¾lêT4N2=⍝᫱ìíḄkᶭA.#okᶭA.îῚ᜜᯿oñ⌱òB.#ᶭὶᔠᓄᶭB.ôõîῚ᜜᯿oA.ᓫ¥#ᶭC.᪷kឋC.ᐰõῚᑁ᯿oB.ᓫ¥D.#ᶭ+᪷kឋD.ᵨ▢⍝÷ᡈùúûüý᯿oC.#ᶭ+Ë◀ᡈþÿ᷈E.ᶭὶᔠᶭD.#ᶭ+ᓄᶭ+E.ᶭᫀᙳា80.▢⍝Ὶᑁ᯿⌱E.ᓄᶭ+#ᶭḄ"ᵨᘤ%&84.(⚠*+,IIb/0⁚2஺45ាḄᶭᫀ%&75.89ᨬ᧕<=Ḅ>?@&A.▢⍝LMNᘤA.᪷ឋQRA.BῚB.▢⍝STNᘤB.ᓫVᶭB.DῚC.┐TNᘤC.ᶭXᶭC.FḸ|)[TNᘤD.ᶭ%\0ᔠᶭᡈᓄᶭD.IJKE.᪷_᷈`abcᔠᶭNᘤᙳ⌱lᵨE.d9E.mᶭ81.ᨵᐵ▢⍝g᜜᯿Ḅrs76.ᚖg᷈Ḅh5ᔠᳮjhk&tu⚗@┯xḄ&85.(⚠,yz{%IB2/R}~ᶇ--ᓿRᳮῚ0□A.hA.g᜜᯿◤Ὶᑁ᯿ឋ(2ஹ25),⊡ᐙᶭ&ᔠB.ᥕhA.RᐰᓄᶭB.ᓫV᜜᯿ៜC.h+h᷈B.ᐰg᜜᯿D.h+ᜮ⚔>hC.¤¥¦/§ὅῚᑁC.ᐰg᜜᯿〉ὶᔠᓄᶭᶭª«⌱᷈%}¬E.h+h+ᜮ⚔>hḄb}¬᯿᪷_`a〉⊡D.Ὶ®ᾭ°[ᓄᶭᐙῚᑁ᯿77.ᾯ²᷈Ḅ᯿h³´&E.R▢⍝ÁÂῚᑁ᯿ὶᔠD.▢⍝Ã1/3᷈§ὅᓄᶭA.µ᷈¶·ᓽg᜜᯿ᒹÇῳÉÊ0ËÌ86.¤§ὅ41Í11ÎÏÐ(Ñ᷈ÒB.¹᷈g᜜〉᡽ᜧl-2cmÓ(Ôᐰᑗ◀×ÎØ▢⍝ÙᑣØE.ῳÉÊËÌ᯿⊈.ᝣÝ(⚠ᨵÞ5cmßà0⁚TC.ᙠ᷈g᜜ᔜ4cmᐜâãäXæᡈCo60ræ᯿ᱥ0⁚TêëìᳮíÝ%}ᑖùᵨᵯÐæ⊡ᐙᑺôᓄ,û§ὅḄyz{ü%&D.ᐰᾯ+⚠ïðñ᯿82.(⚠ýÙᶭḄᜐᳮÿA.⚠ឋE.ᐰᾯஹᐰòñ᯿B.⚠Ꮇឋ78.᜜▢ᓫVᶭḄᑺô%(DT)&A.ᗐᔜ⚗ḄᑖC.⚠ᑖᓄ!HIb%⁚'A.60-70Gy/6-8ᕜ()B.*⊈,-./0⊈17

17D.⚠ᑖᓄ!Hlb%⁚C.▲ᑴᵨB.S'()D.0£ᙢ¥ᵨC.G0E.⚠!E.§Gᙢ¥ᵨD.G187.6ᑁ89ᑖᓄ!:᷈<-=>?@8ABCDEFGHIJᶭᐸᢣ92.~{|^ᶭt[E.G2NOA.ᓫªᵨ97.«⊈¬ᨬt®¯[A.PQR%STFB.᜛±᯿rḄ⊡ᐙA.ᾯ¬B.ῚV9cmC.FG⊡ᐙB.µ¬C.:᷈Z-=>?@8AD.F¶JᶭᵨC.·¸¹¬D.[9ᑖᓄ!E.FJᶭᵨD.ºA¬E.C+D93.~{|^ᶭᶭᦔᨬcḄOE.·¸µ¬88.ូឋ:᷈Ḅ^ᶭ[_`abcḄᶭᦔA.·98.ᵫ½¾¿À«ÁḄÂÃ[A.ᨵfᑜḄhᔠ^ᶭB.«A.20cmB.jfᑜhᔠ^ᶭC.ÄB.30cmC.ᐜlFmJᶭD.Å⚠C.20~30cmD.ᐜlFmJᶭᯠGmᓄᶭE.ÇÈD.25~40cmE.lFopᱥ^ᶭ94.^ᶭËÌÍᦪ(TGF)ᙠAÑÒE.40~45cmÓÔÕAᨵ^ᶭÖ×89.Jr^ᶭᨬtᵨḄlvO99.«Av½ÙῼQR%¬᳛ÜA.=1[A.᜜᯿r(z{|^ᶭ)B.0.5~1.0A.10%ÞßB.~{|^ᶭC.>1B.30%C.᜜᯿r~{|^ᶭD.<0.5C.0D.ᑁ᯿rE.<0.25D.40%E.^ᶭ95.âJrãäឋḄᐵÍE.20^30%90.Jr^ᶭḄẠ[A.âᔠcḄ:᷈çèJ100.««éêçèëᱏíA.JrᱥᳮrãäḄ□ឋ᳛Ü[B.ᑺB.ïâḄ:᷈çèJrA.70~80%ãäC.:᷈JrpᱥB.60^80%C.ïâḄ:᷈çèJrD.JrᱥᳮãäC.50~60%:᷈Jrpᱥ-:᷈D.ãäឋ¸âᔠcñjD.40^50%E.ᑺJr■-ᐵ:᷈E.90%E.¸çèËòᕜᨵᐵ91.[~{|^ᶭ101.Ḅᳮᜐ96.ᜧ¯õö÷øᱥçèùúûA.ᙠᵨ[᪗ýÒþÿ
A.ᐭᜐஹᾭᜐ!ᜐB.ᵨA.M$B.ᾭᜐஹῼ'ᐭᜐ(!18

18,-ᜐ110../01ᑖᓄ45ᾯ78Ḅ9᳛D.<┝>ᜮ@78ABCC.ᾭᜐஹ!EFᜐGHIᗕ)*+ῼ'ᐭᜐA.10%!@cE.ᓫ}XᶭB.ᨵqr4ᑁஹឋᶭ107.cឋ4lḄC.X
ᱏr4lḄ(D.cᶭ+ᓄᶭhiXᶭḄᐵᜧ᯿E.ᓄᶭA.cឋ4lḄxyD.ᨵqrḄ——ᑈ¨©¦ᱯ«103.᷈⚜Ḅᨬn⌕¡E.ᑈ9´qrstஹsµ(B.cឋ4lḄ⌕X9vA./0¢£ᶭᵨᢙ¡ஹ®¡¯xᜐᳮ112.᪷·¸¹º»¼¯45Ḅᑖ¢½B.ᔲ¥ᨵ'¦§C.°±²®¡³⌕ᨬ¾¿ḄÀᜧMᳮ¢£CᜧC.ᔲÁÂ᦮ᑗ◀A.Ì5ஹ5ஹ./01ᑖᓄ5D.X
ᱏr4l((ᜧ/01ᑖᓄ5D.Æ᷈ᔲCÇÈឋcB.Ì5ஹ¢5ஹ./01ᑖᓄ5E.Æ᷈ᜧ.E.1᯿ḄÉÊ˾¿(ᜧ/01ᑖᓄ5cឋ4lᦋN104.¥ᨵnx'¦§᷈cᶭÍ1ᑖC.Ì5ஹ5ஹᜧ/01ᑖᓄ5Îᑺ³(Ðᑺ³ᑖÑC108.45cᶭ½4ÓÔᓄÕ(¢59ᙠ᯿A.1.8~2Gy/νгC50'60GyD.Ì5ஹãä5ஹᜧ/01ᑖᓄA.3ᨴ!<5(¢5B.2~3Gy/νгC50~60GyB.12ᨴ!ABGÆᜧ½<óþÿ
D.C+S᷈஺ᘄB.⊈-./E.S+R+SA.ᗕC.1᜜345114.=ᜮ⚠*@ABᩭDḄE
ᨬFB.D.17./ᵨHᔠᶭJK(C.$LᾭNᜧ345PQᗕE.1ᑁ345+A.R+S)*+19

19B.S+RA.UVᱥ
XYZ[
E.ᓄᶭ+`aHᔠᶭ⚝:\]ᔠB^C.C+S124.cVdefghḄᑖᓄjB.UVᱥ
U⍝ᛋm
nD.R+S+Ro7᜜pA.cVqrE.S+R+SC.UVᱥ
YVs
⚝\]ᔠBB.cVtr115.UV⚠./ឋ345ᶭw⌱D.UVᱥ
⚠*ᙽ
C.z{|gA.ᓫ~᜜᯿⚝\]ᔠBD.qgB.X(r)X(r)E.UVᱥ
U⍝ᛋm
5ᔠᡈᵯ⚠*ᙽE.tqgC.ᓫ~᜜᯿120.Ḅូឋ᷈◀E125.ᗕᶭqf+
ᶭ$⌕᜜ᵨD.ᑺ᳛¡ᶭA.ᑖᓄA.¢£ᶭE.¤d¥᯿B.¦§AᩭDḄB.ᓄᶭ116.UVᑖᓄE©ᓰᔜ¬ᳮ¯°Ḅ±ᑖᦪ³C.34ᾙ᷈C.ᶭ+ᓄᶭA.50%D.¶·¸ᾙ᷈D.hᱥᶭB.60%E.¹⁐»᷈E.᜜¼`aᶭC.70%121.¾¿◤ÁÂt126.ᗕÃgÄᨵÆ\ÇᨬÈᓫḄÉÊ(D.85%~90%A.ÑὶᔠA.ÍÎÏ᩵E.100%B.Ñ1/3ᜐB.¡ÓUVÔÏÕ117.UVḄFÁᒈᑖ³ÚrC.d1/3ᜐC.YVtÛXᱏÏÕA.2rD.q1/3ᜐD.MRIßàÏÕB.3rE.qὶᔠE.ᐝâãäÔÏÕC.4r127.åæÃgçè᯿ᑺ122.cVaÑᑺ⌱ᵨD.5rA.150cGyìíîA.30GyE.6rB.180cGyB.40~50Gy118.fUV᷈ïðYV
ñ⚠ᨵ.C.180"200cGy/345
ᨬó᯿ôᨬÄᵨC.60GyD.230cGyA.õὡÑô+õ⚠ᚖøôD.70GyE.>230cGyB.õὡÑô+⚠ᑗôE.80Gy128.ûḄᳮ¯°◀E᜜:C.☢⚠ὶᔠô+c⚠ஹ┝ÿᑗ123.(T1N0M0)ḄᶭᫀA.D.ὡ!+☢!$%+⚠'ᑗA.᪷ឋ*+B.-ᑖᓄB.᪷ឋ0ᶭC.234ᩭ64E.ὡ!+ὡ8+⚠'ᑗC.᪷ឋᓄᶭD.9:;<᷈119.?@ABCḄDEFD.0ᶭ+*+GᔠᶭE.ូឋJ⁐L᷈20

20129.NOPQ?RஹTUῚWḄ!0ᶭᑺYD.᜜ὡ[1.5cmᜐᶭA.3000cGyE.᜜ὡ[81.0cm1.5cmᜐA.ᓫa0ᶭB.4000cGy139.ᐰyz{|}~0ᶭ〉FB.᜜᯿c+defᶭC.6000cGyA.⚝ᑁ᷈C.+!0ᶭ+*+ᶭD.8000cGyB.⚝ᑁ{|♆ᩭ6Ḅ<᷈D.ᓄᶭE.9000cGyC.⚝ᑁ⊈ᩭ6Ḅ<᷈E.᜜᯿c+Ὶᑁdefᶭ135.ᚖDs⏚ឋuv᷈Ḅ᯿cᑺD.ᑖᓄஹ᧕ᾯᦣḄ⚝ᑁ130.hῚᨬjBḄ'kFYl?ḄFូឋ<᷈A.'A.30GyE.ᾯᩭ6Ḅូឋ<᷈B.hRB.40Gyno.᜜▢ᑖᓄnᔠ᜜▢᪷+Qῳ9¡¢£C.NOC.45~50Gy++8ῳ᯿cᑺY¤¥¦DT§D.¨©ª«D.60GyA.10~20Gy/l~2ᕜE.ª«E.70GyB.20'306±/2~3ᕜ131.TU0cᶭᜫ³Ḅ´⌕¶·136.¸ឋᾯ᷈¹*+ᐰᑗC.30~406±/3~4ᕜF◀+8FᔲÀ0ᶭD.40~506±/4~5ᕜA.º'»B+9¡¢A.◤0ᶭÂÃ◤2E.50~606±/5~6ᕜB.º'»B+¼ᙢB.◤0ᶭÄ◤ᜧ141.᝕ឋ65Ç·BC᜜▢<ᱥÉÊC.9¡¢+¼ᙢC.◤0ᶭÂ0cᑺYËÌÍÎÏᐭ▾Òῳ9¡¢¦Ó§AÞ▢™<ᱥ3.5X3X3cm3,çRè▲D.º'-Ôᡈº'»B⊤☢ëìᨵîïð⍝èPò1cm,+!D.◤0ᶭÂ0cᑺY᯿c'kᙠE.º'-Ô+¼ᙢA.ôῳõ132.TUḄ9¡Ö×´⌕ᑮE.ß◤0ᶭàᑗáâB.öῳõA.⚠Ù9¡¢137.⚝᷈ḄᶭᫀãC.ῳõB.ÚῳÛ8Ü9¡¢A.ᓫa*+D.᜜▢õC.T9¡¢B.ᓫa0ᶭE.ῳõ+᜜▢õD.Ý9¡¢C.*++0ᶭ142.᜜▢+!0ᶭ8ᨬ÷*+Wø¥E.⚠Ù+T+Ý9¡¢D.*++ᓄᶭ0ᶭ8133.TUùᔠᳮḄ᯿cûüE.0ᶭ+ᓄᶭA.ý2ᕜA.ᓫ•ÿ☢138.ᚖ᷈ᶭḄ⊤B.2~4ᕜᙠ#B.ᓫC.5~6ᕜA.᜜Ḯ——᜜ὡ)*C.☢ஹᡂᬪ+1/3ᜐᔣ/1.5cmᜐD.8ᕜ56᯿8B.᜜J——᜜ὡ)*E.12ᕜD.9:;☢+Ḅ1/2ᜐᔣ/1.5cmᜐ143L⚠?NOῚᑁRᶭSᜧUV#E.9:;C.᜜Ḯ——᜜ὡ)*+ḄKF1/3ᜐᔣ/1.5cmᜐA.WXYZ᥅\ஹ]^\ஹ_`134./=>?ᨵḸBCDᡈFDẚHIWᱯ\21

21C.bc/2cm,dLKeB.WXYZ᥅\ஹHeymanfg᜜5cmD.h+iᘤḄ᯿8kᜧ\ஹ]^\D.bc/5cm,dLKeE.h+iᘤḄ8+lmknC.WXYZ᥅\ஹHeymanfg᜜2cm\ஹ_`Wᱯ\2.opqRᶭr〉ᵨu#E.bc/2cm,dLKeD.WXYZ᥅\ஹᓅwxyᘤR᜜3cmA.z{|▲ᶭ\ஹ]^\148.dLᑁ~ᑖᓄ?B.zᳮᑖᓄE.]^\ஹHeymanfg\ஹ_`~IFᶭᑺWᱯ\mV#C.᷈C144.L⚠?ὅῚᑁRᶭᕜA.20'30GyD.᷈op-6Gy,᯿8qV15ᑖRᶭu#B.3040GyE.᷈A.Kᑺm᳛Ὶᑁ᯿8C.40Gy3.ᨚឋop¢᯿8ᨬ¤ᵨu#B.Knᑺm᳛Ὶᑁ᯿8D.40"50GyA.ᜮ⚠¦᷈C.ᑺm᳛Ὶᑁ᯿8E.>60GyB.§?D.nᑺm᳛Ὶᑁ᯿8149.dLᑁ~nᑖᓄ?KMRIC.¨~q©᷈ª#dL«¬஺¤ᵨIFE.®/¯r°ᶭ±ᵨ#D.²³ឋh´?145.L⚠?᜜᯿8µ¶·Ḅ¸ῚA.ῚᑁᶭE.᯿8Ḅ᪗ºV#B.ᓫ»᜜᯿84.¼½¾ᱥÀÁ®ᑖÂÃÄV᪗ÅÆA.Ç)ÈC.Ὶᑁ+᜜ᶭB.L4~5q◣ËÌÍᨬÎÏ#D.opqÐÑC.ÒCᜮᑁ1/2A.G0஺E.ᶭ+ᓄᶭD.®KeVK+;ÓB.G1F;150.ᙠᓿÕ?K;8+ᨬÎÏḄ᷈°#C.G2E.ᒹ×®/ᔜ⚗A.ÚឋÀÁ᷈D.SÍ146.᝕30Ü▢⍝rßᑣá⊈1ãä#åæ]çèéL⚠3.5cm,êëLB.⚩íÀÁ᷈E.MÍ#¤ᜧîè--éᑖïðᑁ~è⚠ñé#᠒ឋóôèLᑁ~é#nᑖᓄC.õឋ?5.öÀÁ§?⚜■ឋᐰᾯ᯿8$PCI&Ḅ?MRIª#dL«¬#ὅḄᨬûRᶭV#D.üõឋ?·#A.ᓫ»ᶭE.ýþ$Krukenbeng&ÿ᷈
A.ᓄᶭPCIB.ᶭ+ᶭ⚪2000B.ᶭᓄᶭᜐCR᝱C.+ᶭ1.ᵯᘤC.!"ᶭD.#$ᶭᵯ%&ᘤ'()D.ᓄᶭᨵᦔE.+ᶭ+ᓄᶭᐸᱯ./0E.ᨵᾯ2Ḅ45147.6ᑁ89ᶭ:F.Ḅᭆᑺ@᳛BC6.ᾯEFGH᜻JKL᷈Mᶭ)A.6ῚO⚔QRS2cwB.ᘤḄTUᱯឋBWXYZḄᜐᳮB.\]^2cm,6:_᜜2cmC.ᘤḄTUᱯឋBaA.⚜■ឋ᯿ᐰYZ22

22B.ᨵfg᯿4hiE.jᨵ:klូឋ15.noឋῴq9ᶭ〉s2Ḅᨬᜧw/0C.xᜐᳮ11.y▭{Mᑖ}:)ូឋ~lᨬkḄA.⊤ῴq9D.⚜■ឋ᯿⚠ZGH᜻JKL᷈0B.ᨵḄῴq9E.ᨵfg᯿ᐰYZA.KLC.Ḅῴq9B.D.8Ḅῴq97.H᜻JKL᷈᜜f)ᨬḄ"C.T-KLE.ῴqᕜwᾦḄῴq9/0D.ឋᜧ16.ῴq9:ᶭ)⌕0A.¡¢£E.¤¥ឋᜧA.¦§¨᜜B.©ᓄª«12.¬9ᵨ®ᐭᶭᶭB.©◀±"²³´᷈Ḅ¶ᔠᶭC.µC.¦§¸ῚKL(ᓫ½®ᐭᶭa)E¾0D.:¹º»ª«D.¿ÀÁÂÃA.ÆÇMᵨE.ÄÅE.¦§⊈ÉKLÁB.ËMᵨ8.IILIVÊClូឋGH᜻JKL᷈Ḅ17.ÌÍÎÏÐE᷈Ñὅ)ῳ"ᨵᱯC.Ô⊡Mᵨ<5cmḄᮤ.0D.×ᐙÙ,ᶭÛᫀ/0ÎÏ᪷+A.Þßà᠒E.ᦋh´᷈Ḅãä£A.ᓄᶭ+ῳåᾭᕜwiᶭB.Fßç)èៜB.±"ᶭ+êë@+ᓄᶭC.Fßç)xèៜC.±"ᶭ+êë@D.Þßà᠒)èìៜD.ῳåᾭᕜwiᶭ+íῼiᶭE.Þßà᠒)xTៜ13.ïÅ9Ḅ᜜᯿ᶭð)ñÌ⚗xóô0E.ῳåᾭRõ⊈öᕜwKL9.KLGH᜻JKL᷈᠒ឋᶭ+±"⊡@A.ì¨ᜐᜫùKLឋ÷⊈4/018ÎÏÐE᷈Ñὅúû)ῳ"0B.ì±"ᜫùᨵ>10cm4ᮤ)ᶭÛᫀs/0ÎÏA.üý4᪷ᑗ◀+C.ᜐ+ᜫB.1ý4x4ÿA.✌⌱ᓄᶭᐰῳᶭD.ᜐ+ᜫ+C.Ḅ▤"E.#$%&'1L8ᨴB.ᐰῳᶭᓄD.)*ᩭ,-./᝱1.ᶭ14.2345678$E.)*ᩭ,1./᝱-.9ᑡ;⚗-=>?C.ஹᓄᶭ.A10.ᡃDEF᜻H56᷈ḄᱯKL?A.‒N56OPD.Q᷈ᶭ+ῳRSᾭᕜVᶭA.WXូឋ[#\Xូឋ]B.^ᑁ56OPE.Q᷈ᶭ+ῳRSᾭᕜVB.WXូឋ`#\Xូឋ1aC.^᜜56OPᶭ+ᓄᶭC.WXូឋ]#\Xូ[D.cᑁc᜜56OP19.defg)*᷈deᑗ◀jk;⚗-◤q.r▢tᶭ?D.lᨵWXូឋE.ῳno56OP23

23A.wx◚dzjB.|ᣩB.wx~⊡jC.C.de24.ᾯ᷈jkᶭḄᑺ?D.ᳮḄᑺᑖD.ᐸῚzjA.3000cGy"4000cGyE.¡ᐰE.▋£ᑗ◀jB.4000cGy"5000cGy29.¦k§ᢈjᨬR⌕Ḅ«K?20.Nᑡ¬4ᶭgᑣ9ᑡ;⚠-=>?C.5000cGy"6000cGyA.°w±ᕒ■´7A.T1-2PSAº»10ng/nd,zjᡈᶭD.6000cGy'7000cGyB.°w±ᕒḕÅB.TlbT2bᶭÈzjᶭᦔ1ÊE.>7000cGyC.ḕAÌC.T3ᶭ`ᑁᑖÍᶭᶭᦔ1Ê25.I'ÏÐ4ḄᶭÑL?D.±—ÓÔD.T?ᑁᑖÍᶭLRA.ᐰᗕᑗ◀E.±ᑮᨬØ>Ḅ᯿E.Hb-T3?ᶭ+ᓄᶭB.ᶭ30.Nᑡ¬4ḄÛÜÝÞÌ᯿,ßàᵨ:21.áâ4g8ᮤzj〉Ñå?C.îïðñA.þ-60A.æ'áâ4D.ᐰᗕᑗ◀⚠òóB.ÿT92B.çᨵáῚᡈèéêëE.ᓄᶭC.⁑T37C.ç≈ஹíêë26.`x(r)ø1ù|#úᨵ9ûᱯK?D.ỚT31D.⚝ᑁA.RBEOERE.Ớ-125E.ᶭ"#$Ὶ&'ᡈ)*+⚝,ẚ.ஹ+01"B.RBEᜧOER331.4ᑡ67ᶭḄᶭᦔ22.:;<7᝞>?@⚠BCDEFG⚠C.ᱥᳮᑺLᑖNOA.᪷QᚁOBCSTUḄᜐᳮWD.ᱥᳮᑺLᑖNORBEᜧB.᜜᯿ᨬOA.⚠[\]ᶭ^_`aOER3C.tuv᯿ᨬOB.⚠[⚜■ឋᶭE.ᱥᳮᑺLᑖNgh-60ḄklD.᪷Q᜜᯿wtuv᯿ᶭᦔxC.⚠[⚜■ឋBCDef27.mnlopᶭḄqr᪵|}ḄᐸrWD.ᓄzᶭ{^_`aE.᪷Q᜜᯿ᨬOA.ᑺLᑖNOE.⚠[BCDefᓄzᶭ32.x⚗rtuB.ᙠᶭ23.Ὶ71997UICCᑖ_N3Ḅ᪗A.rWC.¡B.«¬A.G⚠BCDEF3cmD.Ὶᑁᶭ¢£¤¥¦§¨ᑮᶭ[ªtuvᶭC.ᾯB.®⚠BCDEF3cm¢┐³¡´µ¶D.¿ÀC.¯⚠BCDEF°3cm-6cmE.ᢈQE.ÁᾙD.¯⚠BCDEF3cm±^28.lopᶭx¹qᵫ»¼½¨¼ᑴ¼ᑴ33.ÃឋLÄ⌴(LET)gÉÊËÌḄᐵE.⚠BÎDEF°6cmqḄÏᶇªÑwÏᶇ¢vᐸᨬÒrWᜧrWA.+ᐵA.Ó24

24B.ᨵÕᐵÒA.ὃ⇋\¯¢vஹᑺLஹᑖØC.ᦋÚÃḄLC.ᨵᐵÒḄÛᫀ¢ÝÞᔜtuḄàᦔᑺLD.ᦋᗐÃḄLD.ᐵÒ\âÓB.ὃ⇋¿ÀE.??\äᑣ?æE.ᨵ᩽è⌕ḄᐵÒC.ὃ⇋ê᷈Ḅᦔ43.h-60ᶭí{200KV-XÃᶭíᨵᐵ34.ñɳòÊóᑺ-5-ôõö÷(Miso)WüýḄÌ¥þÓḄÿ
D.ὃ⇋ᑴḄᑺA.ᵨA.-60ᶭḄ!"#200KV-X(E.ὃ⇋*ᑺḄ!"ᜧB.-./01Ẇ339.678ᱥᦔ(REB)>B.200KV-X(ḄᦣA!"#-60ᶭC.CDᵨḄᦣA!"ᜧA.X(6ᐵD.EFGHᵨC.-60ᶭḄᦣA!"#200KV-X(B.-606ᐵḄᦣA!"ᜧE.-ᙠKẆ3LMᜓC.OT376ᐵD.-60ᶭḄᱥᳮ!"#200KV-X(35.TUVWḄ஺YZ[\ᢥ^[VZ_Ḅᱥᳮ!"ᜧ`D.X(a-60bc1376ᐵE.200KV-X(Ḅᱥᳮ!"#-60ᶭA.IGyh2GyE.᯿AḄjk8ᱥlmbᵨnḄᱥᳮ!"ᜧ#pḄᢣ᪗6ᐵB.2Gy~3Gy44.tuX(᯿AvVWwᐙ[\
ᵨ40.yz{ᱥ|}n~᪗MaC.3Gyh4Gy7AᨬjḄ
A.D.4Gyh5GyA.GOoB.tᑖᑺE.5Gyh6GyB.G1C.t᷈(☰)Ḅᑖᑺ36.L-QḄᙠὃ⇋C.G2D.tᑺA.-VWD.SE.VW⊡¢ᘤB.¤-VWE.M45.X(r)(ஹᵯ©ª«ᔠ᯿AḄᱥᳮᳮ
C.᷈41.®-192¯A°ᵨ±²³᯿Av-60,⁑-137Ḅ¶A.ᵯ©ªḄptᑺ·X(r)(ḄpD.¸¹
tḄºᑺE.A.»¼#½¾7®T92°ḄB.X(r)(Ḅp¿Ḅᑺ·ᵯ©ªḄᑺᑖÀ"ÁÂᨵᦔᶭÄஹ37.᪗MḄÅᑖᒘᶭB.»¼½ᳮ7-60ஹc-137C.X(r)(Ḅᢣᦪᔾᦈʾ·ᵯ©ªḄ6A.Ëᕜ᯿AÍÎaËÏ[ÎaËÎᑺ°ḄᑺᑖÀ"Ápᜧ7ᑺÐjÑaÒᜧᕜᑺC.ÓT92°Ḅr(up¿ÔÕD.ᵯ©ªḄᨵᦔᶭ·X(r)(ḄᢣB.ËÏÖÎaËᕜ×ᜩaËÎÙ◞4h5⊦ាÝÞᦣAßᡂ⊡¢ᦪᔾᦈʾÂvaËÎᑺLáL3GyD.®-192°Ḅr(up¿ÔÕE.ᵯrªḄᨵᦔAâC.ËÏ×ÎaËᕜÍᜩaËÎÙ◞4h5⊦ាÝÞ»¼#½¾ãäÂvaËÎᑺLrL3Gy46.[åÝḄᶭlæç
E.-60ஹc-137r(uptஹD.ËèéÎaËᕜ×ᜩaËÎÙ◞4h5ÂÔÕ⊦êA.Hᵨᶭlæë½ᘤvaËÎᑺl.l~L3Gy42.-60ஹÒíᘤÕHᵨMîB.ïðᶭᢈòḄ⌕ôaõöὅøᑮ[E.ËÏ×ÎaËᕜ×ᜩaËÎÙ◞4h5ᘤḄúḄ
åp—〉ḄýþឋḄᑺLL2GyA.ᡂᶭᵨ᯿C.ᑭᢈ᤮38.L-Q%&ᙠ()*ᶭ+Ḅ,ᵨ-⌕/0B.ᦋ345ᑺ᳛D.ᑭ8ὅ:ᶭ)25

25©ª᪗¬J:E.ᑭ᯿+=>?@B.ᶚ¨᷈A.¯FᜧC.±£¤᷈B.¯²³´a47.CDEḄF᷈HIᑺJ70GyஹDḄD.ឋ᷈ὊNᑺTD5/5J35Gy,RSTU᯿C.¯Fᜧ+¯²³´aVᫀḄᑺᑖY0☰[\F᷈]ᑺJE.µ¶·:¸E65Gy,ᑁḄ`aDbcdᙳᑺJD.¹º»¼ᨵ¾ឋᓰ?360GyRS᯿ḄᶭfghJ052.DEᾯ{|ÁÂ⚝ᑁÄfÅᑁÆញ©ᜐᳮᑣÊËÌ/0E.¾ឋᓰ?3+¯²³´aA.1.08A.ÍÎ⚝ᑁÄ57.Ï᜻Ñ?ᙠÒÓᑁḄ᡽Õ/0B.2.0B.ῃ×A.ᨵØÙC.0.86C.ÍÎ⚝ᑁÄ+ᙢÛÜÝ☟ßB.àØÙD.1.86D.╋☟ᑺC.âãRäE.0.5E.åæឋᑭçᑺD.èé&48.CjkEḄl\`RmnSo]᯿VᫀḄᑺᑖYJ0☰[\F᷈]+53.DE?@5êᑁᑖëìíᡈE.⌮ᔣ᡽ᦣpᑺJ70Gy,☰[ᑺJ63Gy,qrᑺ´ᑁᑖëòᔠôõz0J35Gy,ᐸᶭhJ058.AnnArborᑖúûḄüý/0A.£¤DEA.2.0A.vtᑨª⚜B.B.0.5B.ᶭḄC.C.0.8C.ᨵὃ⇋ᙽᜧ⚜ḄD.D.0.56D.ᶭᵨ!"E.ᜧ$%E.t:uvTE.&'ᳲ54.+,-./ḄX1ᨬ3449.⚠yjkEaz{|}/0Ḅ5678A.jk~A.:;3<=B.k~ஹ⚠┝:B.>▲ឋA59.Iஹn,G᜻IJ◤⌕MNᶭOᓄQᶭḄ〉S8C.ῳῚC.TSUᓄA.VWXὅD.kஹkD.ZB.ESR>60mm/bE.DE.cAdefghC.iῼᨵᜧᙽ50.ឋ᷈Ḅᶭᑣ/055.Jkᨵ☢mஹ⚠mOopqrst☟ᾭ᝼Zrxᔾ!D.z⁚|ᓄ/A.ᑗ◀",rsmX1ᱏo.iῼᙽ;ὃ⇋8E.JU3B.ᑗ◀+ᓄᶭA.;ACTHᔠ560.rG᜻IJᧅ᯿NbrC.*ᶭ᧕

26E.´.JC.ᵨ°µ¶A.ᓫ¸¹º61.¼᜜᯿Nbr¾ᑡÀ⚗7MD.ᵨÂᡈÄ᯿NNᶭÅ?@ᑁ>ABᶇ9DEF/3ᜩB.GHឋJKᶭLM᯿6D.HDR,$ὃ&1.5cm,ᑺ+3000cGy/5O8C.□RA.ᐰ9+1/3ᜩO4ᜩD.V⍝XYB.ᐰ9E.HDR,$ὃ&1cm,ᑺ+3000cGy/51/3ᜩE.Z[\]C.^63._`aᓻcdᒹf668.g.ᑡᐵjkᑡlmnḄpD.┝^tMuvḄ26A.ᨵrῚmnE.ᑁ9^A.kᑡlyzᨵ{|⌶~B.nx73.x9]ᜧὅMB.᜜ஹZῳmnᡭᓫᶭ6C.IxᙠkA.ᶭᦔM345D.xC.᜜ஹZῳmnᙠB.ᶭᦔM345E.ᨵ¡¢£D.]᷈¥¦¢£§¨©ᡂ⊈¬C.®ὅᶭᦔ¯345°±64.Zᑡᨵᐵ²³´ḄptM┯¶Ḅ26mnD.ᶭᦔ°±Mᶭ345A.
ᳮᒹfᐺ¹Ḅº»¼½¾᷈E.⊈¬mnmnE.ᶭᦔ°±Mᶭ345B.Fᶭᑺ+¿ÀÁᜧÂÃÄ69.9᪷FM¥¦^ÇÈ4dÉÊËḄ¦AÌ674.9᪷Fᶭ6C.ÍᑖxMᐰ¦⌕¬FᶭA.A.ÐÑ¥¦È4᳛MÓaÔÕ᳛D.Ö⌕2⊈¬mnB.┝B.×¥¦È4᳛ÔÕ᳛ᙳᦔE.×ᶭÙÚC.ÛÜC.ÐÑ¥¦È4᳛MÓaÔÕ᳛65.ῴÞ᪷ឋᶭḄßàMᩩ×6D.ᑁ9D.ÐÑÈ4᳛MÓaÔÕ᳛A.âᙠ‒äᐵ⁚d¦E.EFæçᜐE.ᶭᦔéÄB.ZâᙠêëZì70.¥¦íx9Ḅᔠᳮᶭï75.ðcñᾙ᷈MFkᶭ᯿óÌ6^Ḅᢣõ2627

27D.40k50%A.Êøᶭ^80.ùúᨵûüHIஹIVஹVIVIḄüᑖ⚝º»ÿ
E.54%85%B.᷈10cm!"#85.$%&'()ᑗ+,-./ὃ⇋#C.᷈15cmA.Ḹ5A.67᡽ᜧ'(ᑗ◀(D.ᑖᓄ>Ḅᾙ᷈B.ḸABB.()CDEᶭE.ᾦHᾙ᷈C.ᚖJ≈LC.ᓄMEᶭ76.PQRᾙ᷈(SCDEᶭḄ〉/U,D.V≈ᒹXY•⚗#D.`ᐝEᶭE.⚠☟ᾭ_A.bcdeḄ᷈E.mnEᶭ81.f%&gᑖᓄh&iᓰkᦪB.᷈dᜧ
op'(ᑗ◀,᧕rsḄ#86.$%tᒈvwxYyz⚠{Ḅ|☢~#C.☠⊈,᧕rsᑗ◀A.10%A.⚠⚠4D.ᨵwB.30k45%B.⚠2⚠5E.ᨵᔣஹᑖᓄḄ᷈C.50%5%C.⚠3⚠677.Eᶭᦔ
ᜮ⚠vᑖᓄ&✌⌱D.70%80%Eᶭ'#D.⚠4“⚠7E.85%90%A.'(EᶭE.⚠5£182.f%&ᨵ$¡¢
B.CDEᶭ⊤¥᷈¦§¨#87.©.%&ª«¬§.®ᨵὡvCDឋ±
²³´#C.ᓄMEᶭA.fῚA.§¶ᗕ¸¡D.bᱥEᶭB.º%B.§¶☢¡E.»¼EᶭC.½¾)~◣C.§¶ÀÁ¡78.f%&gᑺÃ᳛ÅῚᑁ)ÇEᶭD.%)~◣È᜜᯿DËÌÍᵨ./#D.§¶$¡E.S⚝ÐA.È᜜᯿DÌ.ÑÒE.§¶Ô¡83.f%&CDEᶭ)ᜮ.ÓB.᜜᯿DDTlOGy)»ᵨ)ÇEᶭÚÛÜឋῪஹeÞ$ßàᵯâ
88.ãäAᗕ&CDEᶭḄ5åbæ᳛²³#i´#C.᜜᯿DDT30Gy)»ᵨ)ÇEᶭA.ëìCDឋíîïðA.20%ñòD.᜜᯿D¨DT50Gy60Gy.
çèé⊤êஹᮤ)ÇôÃEᶭB.ëìCDឋᾯïðB.30%ñòE.᜜᯿D¨᪷EÃ÷A
6»ᵨgᑺÃC.ëìCDឋ⚠øùïðC.50%ñò)ÇED.ឋᚖD.80%79.f%&⚝súẚü
ýþL§.ᨬ᧕Ḅ⚝E.ឋῃ┛E.95%A.᜜$84.ᡡ᪻()⚠+,-./089.1234(567ᵨ9:;<ḄḄ@A᳛CDEᶭGHIJKL7ᵨB.>?A.10%"20%A.᜜EᶭC.NOB.20%T30%B.VWX᯿D.2SC.30%T40%C.[Ὶ]EᶭE.Z28

28D.ᦱ_H`abEᶭD.c◚efEᶭB.6gD☰iIjᵨkLXmfᵯE.opqg`abEᶭE.6)rKᔠ〉umvwᚖx᯿90.)^z({|ẚ~I⚜Ḅ95.⚝ᑁA᷈IEᶭC.6gDpIjᵨ:⌱?〉ᬪ;A.)|ẚ~A.ᓫoEᶭD.6gDp,jᵨkLᵯum᝞20Mevvwᚖx᯿B.|ẚ~B.rᑐEᶭE.6gDpIjᵨkLXm£C.|ẚ~C.XᑐEᶭ¤¥᯿D.ᑁ|ẚ~D.¦3Eᶭ100.᜜▢(ᓫEᶭᑺ©f᯿BIE.᜜|ẚ~E.ᐰp®¯ᶭ¦3⊡©A.60GyT70Gy/6ᕜT8ᕜI·¸ᾙSᡠ»91.K)¼z(⚜Ḅ½¾ᨵÅ᷈4cm6)96.ᚖ᷈ÀKÁÂÃÄ⚝A.,-.ᨵÈ/0ÉB.60GyT70Gy/6ᕜT8ᕜI·¸ᾙSᡠ»Å᷈2cm6)B.ᔜ|ËÌÍÎA.ÏC.50Gy'60Gy/5ᕜஹ7ᕜIᙠÓ⍝[)ÕC.ÖᳮØÙB.ZD.50Gy~60Gy/5ᕜIᕜIᒹÜ᦮Þ᜜▢3D.EᶭḄᢈoC.2SE.60GyT70Gy/6ᕜT7ᕜIᒹÜÓ⍝[fE.ÖàḄឋáD.NOâã92.)¼z(⌱ᵨEᶭäIᨬᔠᳮḄE.᜜$101.᜜▢(oIÖᳮæçᨵῳéê,ᢈo-./0I᯿ë97.•wíîḄïð᷈IoA.kLXm9᯿EᶭᨬñᓫᨵᦔḄóᢈoA.ᢥõ⚠(öᚖx᯿÷ᒹÜῳéê,-.B.kLᵯumA.ᓫ£᯿B.øùúûwῳéê᯿C.kLXmVWXüqB.w᯿C.ᐰýᜧᚖx᯿D.VWXüqC.£ÿ᯿D.ᐰ᯿ᒹ▢E.ᵯD.᯿E.ῳ"#$᜜▢&93.)^+ូឋ.᷈Ḅ123456789,;<Ḅ45=>?E.AABC90°ᵨ45°102.▢⍝)LMN,OPQRSᬪUVWX✌⌱[ᶭ>?A.^12398.⚝abḄᾯd᷈e⌱fgA.᜜᯿Ὶ$ῳijᾭO123B.mn123$┝p)123q[ᶭrsXtuᵨ?B.᜜᯿ῚῚᑁw[ᶭC.⚞n123A.;zw[ᶭC.ᐰ᜜᯿D.ὡ123B.|}}w[ᶭD.ᐰ᯿|}E.┝p)123C.rᑐ[ᶭE.Ὶᑁw[ᶭ|}94.ᦋḄᚖ᷈X〉ᔠD.Xᑐ[ᶭJ-?103.▢⍝NῚᑁ᯿XnᵨᘤḄE.᪝[ᶭ⌱f⚗>┯Ḅ?A.|}ᑗ◀w[ᶭ99.ᐰ᯿Xn•qrA.┐¡ᘤB.w[ᶭsuᔠᳮ?B.£¤¡ᘤC.¥◚§[ᶭA.¨©ª«¬XᵨX®ᚖ¯᯿C.᣸ª¤¡ᘤ29

29B.´N$´MND.µ¤¡ᘤE.60Gy~70Gy/6ᕜXᕜC.|}ᑗ½¾¿E.ᨬÁÂᵨAq¡ᘤ113.Ã⚠N679Å6ÆḄBᐵÈD.Ὶ12345ᨵ?104.▢⍝NḄ[ᶭÉᑣX⚗>┯Ḅ?E.¨)Ðu>A.▢⍝ÑÒA.ÌÅÍÎX.᷈=XÏe|}ᑗ◀109.Ã⚠NÓḄÔÕB.᯿ᑺ²Ö>?B.ᔜÅᙳeÙw[ᶭC.ῚᑁwÚ=uÛA.Ü.ᙽÞ◀ßC.▢⍝)1/3à.᷈XeÃ⚠N|}áD.A+B+CÙB.ã⊈ᦔæç℉E.A+BD.▢⍝W.᷈Xéê᜜᯿ᑺ²C.᪷ì.᷈Uí᦮Ó᣸ᑡ114.wᶭðñé;<ូឋ.᷈ò▭ᑖE.▢⍝õ▬÷.᷈XeÙ|}ᑗ◀Å?D.øùúûஹý◤ÿ⏥105.ᑡᶭḄA.⌕ῚᑁᶭE.ᔜ⚗B.#$%⍝A.'()72,-ஹᐳ2(110.0⚠2345Ḅ#$67;C.#$=>B.'()24,-928,-ஹᐳ2(A.?@#Aᑁ—C᜜ED.ᜧH%⍝C.'()20,-924,-ஹ2(CIJῳLMᾭO3PE.ᙠHD.'()120,-ஹR1(B.0⚠O#Sᑁ#C᜜ECIJῳLMᾭO3P115.TU2ᶭ1000cGy~2000cGyZE.'()120,-ஹ2(93(\]^C.᠘`--?@#bᑁ#106.IHaghij0⚠2ᔠl▢⍝nopC᜜ECIJῳLMᾭO3PA.ឋuvwᨬrᶭᫀ;D.0O#?@—Cᑁ—B.xyEz{ZyA.ᶭ+}~+ᓄᶭ>᜜ECIJῳLMᾭO3PC.xB.ᓄᶭ+}~+ᶭE.0⚠O#?@#Cᑁ#g᜜ECIJῳLMᾭO3D.ឋwC.᪷ឋᶭp〉᜜P᯿ᑺpῚᑁ᯿ᑺE.111.0ᑁ2ῚᑁᶭD.᪷ឋᶭpῚᑁ᯿ᑺ-pF⊤116.25pᵱឋp`ῼᙊ¡ᙽ,E᜜᯿ᑺ¤¥ᨵᑖ¨஺ª«¬®□ឋp⊈HCG±²ᓣA.0´µ¡᷈·¸஺¹º»¼ὃ⇋¿ÀE.}~+ᶭB.0⚠µ¡᷈·A.ῼÅÆÇÈ᷈107.0⚠2~ZpÁÂ\Ã◤~ZᶭC.0ɵ¡᷈·B.ῼᑁÊË᷈A.ÌῚᨵ3P45D.0Ὶᑁ¡᷈·C.ῼូឋzÎ᷈B.3UE⊈Uᨵ2᪝E.0É᜜¡᷈·D.ῼÐÑÒ2C.0⚠ÓÔÕÖ×ØÙÚ112.0ᑁ2pᨵῳLMᾭOE.zÎÛ212345X᯿ᑺ²>:D.lagÝ2pᑗßà2117.ῼãäᑖåpஹæḄ᪗èA.20Gy930Gy/2ᕜ93ᕜ;¿ÀE.¡᷈éᜧpêᑗßà2B.30Gy~40Gy/3ᕜ94ᕜA.z{ëìz5íÉîï108.0⚠2~Zᶭ〉ðñ;C.40Gy~50Gy/4ᕜ~5ᕜB.z{ᑗòìz5íÉîïA.◚ôឋ0OÕÖD.50Gy960Gy/5ᕜ96ᕜC.LMᾭõö÷3()

30B.à67D.z{ëìz4íÉîïB.᪷ឋ}~ýLC.úûüE.z{ëìz3íÉîïC.ᓄᶭD.þÿ
118.,3cm,D.ᶭ!"#$%&'()*+஺ᨬE.⌮ᔣ᡽ᦣ.Ḅᶭ⌱123E.9:ᶭ123.<=Ⅴ᪵◭A23A.ᓄᶭ128.ᡡ᪻EᙠGHḄI᳛9ᓰ3A.◭AB.MNᶭ+ᓄᶭA.✌VB.PQឋSTC.MNᶭWXYB.[\VC.ZSTD.XYC.[^VD.<='(᷈E._`ᙳb2D.[fVE.cdឋe119.hPij⚜■ឋᐰᾯ᯿NḄᳮqE.[rVst23124.vwx᯿N☢zI00cni2TD50/50:129.Ḅ᪷ឋMNᶭ᷈ᑺ:A.᷈MNdSA.6000cGyA.35Gy40GyB.ᾯ*+I᳛᷈MNdSB.8000cGyB.45Gy~50GyC.ᜧᾯPiMNbdC.7500cGyC.60Gy70GySD.4500cGyD.80Gy85GyD.⚜■ឋ᯿Nᶭឋ᯿NᶭᦔE.7000cGyE.95GylOOGyE.᯿N40Gy_%b¡125.MNᶭᑡ£¤⚜W&130.ᡡ᪻E᪷ឋMNᶭW%¥IᐵḄ§¨23ᮤªIḄᜐᳮᵨ3120.®¯᜻±²³Ḅst23A.ᶭ´EµA.¶·MNᶭA.¸¹4EºB.ᶭPAS½B.XYᶭB.¾¿ÀÁC.ᶭWPAS½C.ᓄᶭC.⊈ÃÀÁD.ᑖÅD.ᱥᶭD.PiÀÁE.ᑖÇE.ÈᐝᶭE.ᳮÀ᩵126.ËÌᾙ᷈YWMNᶭ%131.ÎÅHḄ¸¹23121.¯᜻±ÏᩭÑ3ÒᵨÓᐙᱥḄ¥§3A.HÕᱥSஹ×H◚ÙA.ᨬÎIÚḄᙢÜÏA.Ý⊤☢ßᑺàáâãäªIB.åæB.ᨬÎçèÚḄ:éÏB.êëᑗG<=C.×HíîC.áâÚḄZC.ï¡MNðñD.òóஹôõD.ö÷øùᦑûD.Ò᷈ᑺᑖüᙳᒴE.þ⚠
ᜧE.⚪ḄE.ᓄ132.ᗕḄ!ᒈ#$ᙠ&'()*☢,-:122./0᜻23᷈Ḅ᡽ᦣ7127.9:ᜮ⚠=>?@ᶭBCḄA.⚠E⚠3⌱GA.ᨵIJB.⚠2R⚠4A.᪷@ឋMN@ᶭOP31

31C.⚠3R⚠5\]^_ᒹa&⚗7D.40~50GyD.⚠4R⚠6A.def᷈^ghBiᑗ◀᳛E.45~55GyE.⚠5R⚠7B.dmn?opqᱥsឋti138.᜜▢?ixMN@ᶭ〉z{|ᦣ133.ᗕ?MN@ᶭ{ᨬ~Ḅ7^&┯Ḅ7C.ᑗ◀ᨬḄ???A.ஹឋzA.▢⍝1/3D.ᨵᑭ᷈Ḅ¡᦮ᑗ◀B.ᗕB.᷈t⍝ᡈ£E.dmn¤)¥=¦ᢙ¨^©ªC.«¬᫱®i¯°±C.µ¶·ᜧஹ¸¹·ºD.ᗕ²³´143.»¼½⚠?MN@ᶭᦔ¿ḄÀÁ{D.᷈·ᜧஹᔠ°±&⚗┯Ḅ7E.ôE.ᔠ᜜▢ÄᦿÆÇÈA.½ῚÊËÆÌῚ°±134.9:ᗕ?Ḅ@ᶭÍÎz✌⌱7139.ῚᑁMN@ᶭ▢⍝?^ÒÓB.ÔὅÖ×ÆØÙÀÚA.Ûᐝ@ᶭḄᑺÞßὃ]7C.᯿NᑺÞÆᶭåæçB.¥=ᑗ◀A.ῴâ¯ãD.᷈µᳮìíÆᑖïC.ᐰᗕᑗ◀B.éêxãE.òóᑖ:ÆÔὅôõD.MN@ᶭC.᷈ðñ=144.½⚠?-÷ø^•ú〉ᔠ&E.ᓄö@ᶭD.A]ûìí½⚠?7135.9:Ὶ?@ᶭüýþḄᶭᦔ^E.B]A.⚠ÿ
⚠ᑮḄ140.▢⍝ᑣ⊈ᨬB.A.$%&'()*+,-.567ᶭ⚪:2001B.%&/0A.
⚠ஹ2
ᑁ4ஹᓿHC.=>◚@᧕BCDEFB.2
ᑁ4ஹᓿHஹ1.
⚠ḄῚᑁ7ᶭ+ᑡKL,⚗D..OអQRSTU▢⍝VWḄE..ODUYZ[\']*C.▢⍝ஹ^ᓿ_ஹA.`aῚᑁ7ᶭᙳc)dᑺfghῚᐸjk.ᓿH᳛᯿6136.pqrḄ567ᶭsᜩᑖvᑺD.▢⍝ஹ
⚠ஹᓿHB.wxyῚᑁ᯿6ᩭ{dB|ᑺJS.f}ᔠᳮḄA.<180cGyE.▢⍝ஹ
⚠ஹ2C.Ὶᑁ᯿6ḄᑺfgV
ᑁ4B.180cGy'200cGy141.
⚠⍝⌱D.Ὶᑁ᯿6Ḅᑺfg᎔C.250cGy270cGyḄ7ᶭD.280cGy"290cGyA.567ᶭE.Ὶᑁ᯿6ᵫ)ᑺf⊦/¤¥¦ஹῴ¨Ḅ©ª/«E.300cGy"320cGyB.ᓄ¡7ᶭ+£2.Ὶᑁ᯿6®¯_°w±Ḅ137.᜜▢567ᶭᑺfC.567ᶭ+£ᦔ³A.2030GyD.£A.´µ7ᶭᦔ³B.30"40GyE.¶·7ᶭ+ᓄ¡7ᶭB.¸¹ºC.3545Gy142.ᨵᐵ567ᶭ
⚠ḄC.½ᦔ³32

32C.¾Tஹ¾BÀÁD.ÂÃE.ᓿÄÅD.TÀÁDBÀÁÆᔠE.ᦋᗐÉᔾ8.Ë◞¹ÍÀÁ᷈⚜ÐÑᨬZ⌕ḄE.NKÀÁ3.ÒÓÔ᯿6Õ⌕ᵨ)A..ÜÞ13.567ᶭßàḄᨬáᫀA.᪷7£ÛB.ãäå35æA.ᓫè᜜᯿6B.´µ£ÛC.ÒÓ¡ëB.᜜᯿6+〉᯿6C.᜜᯿6Ḅ⊡ᐙD.⚠=ïðñᨵ$òóC.Ñ567ᶭD.ᓫíîᵨE.AFPᓣdD.〉᯿6+ÒÓÔøùE.ôᔠ£7ᶭ9.¾«ÀÁ°5ᶭḄᢣûE.〉᯿6+Ñ567ᶭ4.üýþ7ᶭᡠᵨḄ14.ᑡA.A.T1N0M0!ᶭB.$%Ḅ&'ឋ)*+B.T2N0M0A.᪷!ᑗ◀01234C.ᡈ$%C.78T,N3M1B.᪷!ᑗ◀;<=>D.ᜩᯠD.BCᶇE᷈C.᪷!ᑗ◀E᷈GHIJKE.Ḅ&'ឋ)*+E.TisNOMOD.᪷!ᑗ◀E᷈GHPJK5.RSᩭU&VWXYZḄ[10.\᜻^_␺aE᷈CᶇஹcE.deᑗ◀fឋ(ᢥ᯿⊤klᩭḄkm)opqrᓄtuᵨᑡ)*+vw15.xyzῴ|!ᶭᜫᨬḄᜫA.pᡂA.R67B,pᡂA.ᜐ3440%85%B.ỚR131C.pᑖᓄᡂB.ᜐ3430%C.—99D.pᑖᓄᡂC.deco80%D.—32E.B+DD.decoᜐ34ᔜ30%E.^R1986.ᙠCT¡᪵␺a£ូឋ¥¦᷈E.deco30%50%11.§Ḅ¨<©ᐵឋ«\᜻^0A.E᷈ᕈᑖ®1᷈(MALT)ᵨᢙ±²³´ᩚ¶16.ῴ|B!ᶭḄ¹Ḅ·ᱥ!ᶭB.E᷈ºᙳA.¾¿01Àᡈ⊈ÀBḄ᪝A.eᑖ_&ᨵᦔC.E᷈pᾦÄÅ◣ÇȾᜫB.¾¿ÉῚB34012B._ូᓄD.ᨵ.┛ᓄC.Îᢝῴ|ÐC._ÌÍE.ÑឋÒD.Ö×34ØÙD.Ó®ÔÕ7.ÚῼÜÝÞ᷈ßàáoâᩭãE.¾¿CäE᷈8ᜐE.å[fឋ17.IçèéêÝÞ᷈ᙠᑗ◀ëA.ì3ஹ4íî12.«\᜻^01᷈B⚜ðḄḄᜐᳮÝÞᩭñB.áóôÜõA.ᓄö!ᶭHῳøùᾭû01A.TÝÞ2!ᶭC.¥¦üÝÞB.BB.D.ýþÿ
33

33c.ᶭᑺᑮ25Gy₞,N3Ḅ᪗!"#A.T2bNlM0*A.q1rst*78B.T2aN2M0D.ῳ-.ᾭ012⊈4ᕜ6789ஹv.w4cm9ᶭC.T2bN2M0B.q1{st*789E.;<ᶭ᯿>D.T3N1M0C.q1|st*78918.IBCDEF᷈HCDᑗ◀KLE.T3N2M0MN᳛#D.q1t*78927.©▭ᑖB«Tis⊤#A.2%"13%E.}~N3A.FN᷈B.30%23.}t^ᡠ▲HT1᧕NH*B.FN᷈®3cmC.20%ST"T2#C.F¯^D.1%A.▲D.°±ឋ^E.UῚWXYMNB.☢◖E.FN᷈³´µ19.[ᑡ]^᜜᯿`ᔠᑁᑖdᶭḄeC.ᳫ᜜ஹ¡.▲ᜐ"#28.¶·¸ᑴºᶭ¶ᑜL#D.¢£¤¥¦◖A.gGleasonᑖmA.¼½ᓽᶭE.}~"T2⊤B.PASpB.¿᪶{C.ÁÂ24.ᶭÚ⚠^HÛÜC.êë¸*᪶{L᡻íÝὃßḄ¯à"#D.ÃÄÅÆᑴ᳛¤gÇÈᜐᜫD.Mᑴºᶭ¶ᑜÊ᳛A.▢⍝ã«ä▢⍝LḄᚖÛæHç▢⍝L10cmE.îïᶭ¶ᑜ᪶{E.ÃÄÅÆᑴ᳛B.▢⍝ã«ä▢⍝L29.ð[ÖñᶭḄ-⌕óô"#20.ᶭË^⚠7Í9ÎÏḄᨬÑ⌱ÓḄᚖÛæHç▢⍝L5cm"#A.ÖñḄõö÷HrøùúûC.▢⍝ãèé▢⍝LYüýឋþñÿA.᪷ឋ᜜᯿ḄᚖÛæHç▢⍝L10cm6000cGy"7000cGyB.ᜧD.▢⍝ãèé▢⍝LB.᜜᯿Ö×ØÙ᯿ḄᚖÛæHç▢⍝L5cmC.C.᪷ឋE.▢⍝Q@RS▢⍝D.ᦔᶭTḄᚖVWXY▢⍝T5cmE.ᵨD.ᑗ◀ᶭ25.ᙠ^ᑡHPVcdeXf!cdSghdi⚠)k/ᐵmᨬn30.Yᶭ7E.!"#᯿ᑗ7A.ᩖ21.'()*+ẚ-ᡈ/012ὅᨬ5A.HPV6dp11dᵨ7B.ឋB.HPV16dp18dA.9ᶭᶭC.ᶭ#C.HPV16dp31dB.9ᶭ:Ὶ<ᶭD.ḕD.HPV11dp33dC.9ᶭᓄ>ᶭE.ᐰஹஹv☠E.HPV11dp18dD.ᓄ>ᶭ9ᶭ31.!"#᯿ஹ᜜᯿x᪷ᶭ¡26.i⚠)Xstiuvwxyᑡ¢)Ḅᔠ¤¥k¦᳛7E.᜜᯿9ᶭz{ឋḄ|}~ᙽXᢥUICCᑖE7A.᪷ᨬ¨22.@AB)ḄᑖEFGὃIJ71LᡠN34

34B.᜜᯿ᨬ¨Ḅ®7A.¦ᱥxᱥᳮᱯ¬C.!"#᯿ᨬ¨A.µ¶·-60Ḅ¹º»B.¦ᱥxᓄ>ᱯ¬D.᜜᯿S᪷y᪵B.µ¶·-60Ḅᦣº»C.¦ᱥᱯ¬°±ᑺ³ᑖE.!"#᯿S᜜᯿y᪵´ᱯ¬C.µ¶·-60Ḅ½W32.¨Wឋ³¾⌴FLETÂW᯿ÃD.ᱥᳮᱯ¬D.µ¶·-60ḄÄź»ÆÇᱥÈÉÊËÌW7E.ᑺ³ᑖ´ᱯ¬°±¦E.ᦋᗐ·-60ḄW+A.ᕈᢣᦪÌWᱥᱯ¬41.+òSóeòôÚXᐸᱯ¬®7B.ᨵÑÒÓᕈᢣᦪÌW37.ãä@᜜¦dFåædÂSᑁ¦dFèédÂ~᷈êA.+òLETöÚeòḄ÷C.Ôᨵy}ÕÖᶭḄ®7B.+òOERöÚeòḄ¨D.ᑺ³SÊ˱ᐵA.y᪵C.+òḄᱥᳮᱯឋÚeòḄ5E.ᑺ³ÌW±ÕÖB.᜜¦dᶭᦔ᝞ᑁ¦dD.+òḄᱥᳮᱯឋÚeòḄ33.×ØÙÚFOER®ᢣ7C.ìíîE.+òḄôê¦ᱥᦔÚeòA.Ý×~᷈ᶭᦔØḄḄ5ÚßD.᜜¦dᶭᦔÚᑁ¦d542.ᶭeXWºùúᵨû⊤ý7B.±×ᩩá^~᷈ḄᦔḄᦋ0E.Sãäïd±ᐵA.XWḄÙþC.ᙠᨵ×p±×ᩩá^ýᑮ38.ᙠᶭᓫ᯿B.XḄ᪵Ḅᱥᦔᡠ◤⌕᯿ᑺ!"#ᑺ!@AᨬᐵDḄEFC.XḄ^_`D.X%r᯿ᑺ!"#A.HIJKLMᑴ᳛D.XḄaᙳ!E.ᨵ)*+)ᩩ-./0ឋ"B.PJញឋR#E.XḄcᑖefᑺ!C.THIU᷈KLMᑴ34.345ᱥ6789:;᪗=>?᳛WJXYZ[\]R43.Xgrhᵯjklᔠ᯿ḄnoEFᨬ/0ḄEFD.uHIU᷈KLMᑴA.HIᶭ#A.GO]᳛vwញឋRB.XYZ[Ḅᑺ!B.G1]E.uHI-------vw\]RC.☰ᑺ!ᩩ-.ᔠᳮᙢC.G2]ᦋᗐJ☰@XYZ[Ḅᑺ!ᐵ39.eLXᶭz{ᵨ}ᔠD.S]~ḄEFD.HIJU᷈ᑺ!E.M]A.ᨵᦔḄ?E.Jᐰᑖᑺ!ᶇᱯ?35.9%ᙠ9F44.ᑺ!ᑣEᐵ¢FB.ᨵᦔḄᱯ?A.A.ᶭ#Ḅ£¤B.¥¦§+ᜧ©ªC.«~¬?B.ᶭ#Ḅ£¤~¬ᱯ?C.ᨵ®¯©ªC.ᶭ²ᫀḄ£¤D.±Ḅ~¬ᱯ?D.ᨵ°ᜧ©ªᶇᱥ?D.ᑨµᶭ²ᫀḄ¶·E.᪷¦uḄ¹ºE.;J»¼½HI¾¿E.ÀᶭᶭᑣḄ£¤ÈḄÉ36.ÂjᶭᐹᨵIឋ!Ä⌴gLET45.ᬪ¹ÐḄᬪ¹ÑE⊤ÓFḄF40.Ë-60zÌᵨ}º=ÍᘤḄ35

35A.ᬪ¹>aÐÔᑺ!ᑖÕÖ×ḄØfC.ῳÚ@54.ÛLCTÜÝ>ÞßḄàµ.ᑡâ¼⚗uXäFB.ᬪ¹>aÐåæᑺ!᳛ḄD.‒èLÖ×A.ëìU᷈%ᜧ⊈îḄᐵE.éêLC.ᬪ¹>aÐÂḄÖ×B.ëìU᷈%Dᒹᐵ50.§Ὶ☟ᾭòóôᔠḄõ⌕D.ᬪ¹>aÐD÷cᑖefEFC.ëìU᷈Eᔲùúûῼᑺ!ḄÖ×A.ូឋþÿD.᷈E.ᬪḄᑺᑖB.E.ឋ46.᷈Ḅ!"#80Gy,ᕜ*+ḄὊ-ᑺTD5/5,TD50/5ᑖ1#C.3ឋ᷈55.AnnArborII:Ḅ;᜻=>?ὅAB40GyC50Gy,DᶭFGH#IKLᦪNḄOPID.JA.2.01.6A.TUVᑖ:W⚜YE.᪶>B.0.50.625B.UV⚜YZTUVᑖ:C.1.62.0C.UV⚜YWᑖ:51.J[\DᶭYZJ]^ᓄD.0.6250.5O`aᙠID.UVᑖ:ZTUV⚜YE.cdeTfA.[\DᶭghE.ijklTm47.☰LᑺḄᙳᒴឋrᢣIB.[\DᶭY3ᨴ56.;᜻=>vᧅx᯿\hZ᯿\z{ᙠIA.☰Lᑁ}~ᑺ☰LC.[\DᶭYᑺḄA.9zD.[\DᶭY1B.☰LᑁᨬᜧᑺᨬᑺB.10zḄ1E.[\DᶭY1cdC.11zC.☰Lᑁᑺ~ᑺ☰52.JdῚ☟ᾭLᑁᑺḄ1ᔠḄᨬDᶭᫀrID.12zD.☰Lᑁᑺ~ᑺ☰LA.ᓄᶭ¡¢£ஹᑭ¦§E.Ὺ1zᑁ©ᙳᑺḄ1ᑁªᜐᳮ57.;᜻=>?ὅZᨵ®⚠W°ῼE.☰Lᑁᑺ~ᑺB.ᐜ³´[ᶭWPT20GyBK·¸¹Jº»BKZijᑖ:☰LᑺḄYZᦋ#+[ᶭZᶭA¡¢£#Iᑭ¦§ᑁªᜐᳮ48.½¾A¿ÀÁ?ὅZ>ᮤÃ7cm,A.I:Æ┝ÈdCÉᜐZÆÊËC.ᓫÍ[ᶭᡈᓫÏÐᑁÑZ✌⌱DᶭrIªᜐᳮB.H:A.ÕÖD.ᓄᶭ¡[ᶭC.IIE:B.ᓄ×DᶭE.ÕÖD.HIE:C.[\Dᶭ53.JḄ[\×ᱯ~rIE.IV:D.AÚWÛÜDᶭA.O`58.Ýូឋ;᜻=᷈ZN:>àáᐰã᯿\(TBI)hḄæᑺ#IE.Öç[\Dᶭ¡ÕÖB.⁚éA.150cGy49.ᶚëì᷈í`îïZzᑡñ⚗rTC.┛ᓄᮤ*ôḄIB.300cGyD.õö◍A.øῚC.450cGyE.O`⁚ஹ᝱úûZB.°ῼüÁᐵþTÿᑗD.500cGy36

36E.ᐰᵯ᯿C.ῳ!E.800cGy.2cm1ᑁ64.$%ᶭ'(ᶭᦔ*+Ḅ-59.45᜻7᷈Ḅᑖ:;<=>?⌕defCD.opqᙢS@Aᡈ!;C▲A.'g$ὊiឋkA.EFGE.B.᧕mn'ᑁB.*G69.▢($%ᶭᑺ⚗C.STᐰop*qCC.⊈JḄKEὅGD.%ᶭrstuA.30Gy"40GyD.ESROὅGE.'($*vwB.60Gy70GyZ¢᪷¤So¥E.IIIஹIV:STG65.%ᶭxyᑁgzᒓ|ḄC.30Gy~40GyZ¢᪷¤So¥60.UNHLḄ⚜ZḄ[\Ḅ⊈]ᓄᢣ`aC}~(⌱CD.50Gy~55GyA.ALTA.ᓄ%ᶭ+|E.40Gyv50GyB.GGTB.$%ᶭ+70.¨©ªd«¬᷈ὅHa:¨©C.AKPC.$%ᶭ+|ᑗ◀Z¾¿Àᔠ%ᶭCD.LDHA.ᓄ%ᶭ+ῳ-.ᾭÃD.$%ᶭ$%ᶭE.ASTE.·ᢝ%ᶭ+|B.ῳ-.ᾭÃ$%ᶭ+61.ូឋ³ḄNHLḄSᳮµ᝱fCᓄ%ᶭ66.}~(Z¹º»¼%ᶭA.ÄÅÆ⚗ÉCC.ῳ-.ᾭÃ$%ᶭ+Ë⊡+ᓄ%ᶭB.ÇᦣÆA.HDRZ¹%ᶭÊD.ῳ-.ᾭÃÍÎῼ$C.ÄÅÆÐÇᦣÆÑᔠB.ÒὃÔ1.0cm%ᶭD.Õᩩ×C.ᑺ5000cGy~7000E.ῳ-.ᾭÃஹÞú⊈ûcGy/8ç10ç/4ᜩ5ᜩ$%ᶭ+Ë⊡E.ᱏᙽ×D.ᵨê192-ì71.ᑡ~(ᨬEýC62.³ូឋ45᜻7᷈ᑖ:=CE.ᵨᑖç᯿A.-.ᾭÃA.Iஹn:Û67.íîï(ðᑡ⚗┯óCB.úþ.ᾭÃB.Iஹn:ÐHIஹW:ÝÞA.◤⌕ᐰõ$%ᶭC.ú᜜ᾭC.ᔜàáâ*B.*◤⌕ᓄ%ᶭD.ᑁᾭD.IllஹIV:ÛC.⚜Zö÷᷈øᐵE.E.ᵱឋIஹII:Û᝕ឋHIஹIVD.!"ᶭ#⌕┐72.,-./0!1ᓄ3ᶭḄ45&IIஹIIIஹIV6763.ḄⅤ᪵◭ᶭ89ᵨ7E.;

3773./0ᑖᒈ᪗6778.0ᑖYT2~4N+M0,V▤rḄY7B.,-᡽ᜧᑗ◀+⚠¡¢A,£u¤!A.ὡ1r+ᐰ⚠ᑗLrB.£ᜧ¤C.ᶭB.ὡ1r+☢1§¨r+C.©ªᑁ¤ᐰ⚠ᑗLrD.ᓄ3ᶭD.©ª᜜¤C.☢⚠ὶᔠr+¯S⚠ஹE.zᱥᶭ┝±²ᑗLrE.«▎¤D.☢1§¨r+ὡ"r+74./0᪷!"᯿ᑁ/´Ḅᐰ⚠ᑗLr83.S0µU•-·ḄᶭḄᶭᦔ¹º»ᵨ677E.☢1§¨r+ὡ"r+A.¼½¾9ᐰ⚠ᑗLrA.¿"´B.±Àᢓᑴ79.ÄÅÆῚᑁᶭ0〉9B.Éʲ-_67C.ËÌÍ⊈ÏÐÑ᳛C.ÉÊ^A.▲ÓÔஹb⊤D.Õ0ᮤD.S"ÔE.ឋ×ØB.ῚÙÚE.SÛÔ75./0ᾯÞß8àᵨḄᑺp67C.ª◣âãÙÚ84.µ.S0!"ᶭV▤Ḅ᯿räå9ὃ⇋7A.25Gy/5ë/IᕜD.íÙÚA.Ûur┐&î´B.20Gy/5ë/IᕜE.⚝^±ẚñB.¯Ûur┐&î´C.10Gy/ë80.᪷ឋᶭᡡ᪻õ0ḄV▤äåᫀY7C.Ûஹ²⚠rD.50Gy/25ë/5ᕜA.÷Ûᡡ᪻õ´urD.¯Ûஹ²⚠rE.30Gy/10ë/2ᕜB.÷Ûᡡ᪻õ´☢⚠rE.¯Ûஹ²⚠r+¯S⚠ஹ┝76.⚜■᯿úûüý¤ᾙ᷈ÿ
Ḅ᯿ᑺC.ᡡ᪻☢⚠+ஹ⚠┝85.!"ᗕ$T2N0M0,!+,-.ᑖ0A.2᪷4ᑺ5▲94ᶭ;ᑣD.7ᡡ᪻☢⚠B.>◤⌕⚜■᯿A.Dᐝ4ᶭE.7ᡡ᪻☢⚠C.>FG50Gy+7ஹ⚠┝B.᪷4ឋK4ᶭD.LMNK4ᶭᑺO1081.Q᪷$᪷4ឋK4ᶭ᯿C.RM4ᶭGy'20GyḄTU▤WXᫀᵨD.ᐜK4ᶭDT40Gy]^ᦔ`>E.2MaK4ᶭᑺ5A.bcdᑣᦋfRM77.⚜■ᜮ⚠.i᷈KឋklmḄB.b☢⚠E.ᓄq4ᶭᨵᦔXoC.b☢⚠+⚠ஹ┝86.ᗕ$Ḅsᳮuvwx$yz9{L|A.z}~B.zuᱥD.7☢⚠A.20%28%C.zᔛuᱥE.7☢⚠+7⚠ஹB.40%48%┝D.zᢙuᱥC.55%58%82.$4ᶭRWḄ⌱E.ᶭN◀᪷D.70%78%A..ᑗ◀38

38E.90k98%C.-ᾭ£¤ᓄᶭ¥RMB.Rᢣ§ᜧ4ᶭ87.!"ᗕ$©᯿60Gy,⚠
C.kª«¬ᨵ®¯]ᑣ°ᵨD.-ᾭ£¤4ᶭ¥K4ᶭD.ᱛ²³A.´µ¥᯿E.RM4ᶭ¥MaᓄᶭE.¶ᳫª«B.RMᑗ◀92.k¸$¹OºḄi᷈97.»U⚠¼½¾¿ÀC.ᓄq4ᶭA.x$A.ÁÂD.¥Ã4ᶭB.Ä$B.ÅÆE.ÇÈ9>¥ÉÊᜐᳮC.Ìᑖᓄ$C.ÍÎ88.Ï$Ḅ✌⌱4ᶭD.ÑឋÄ᪵Á$D.⌼⊈Õ|A.᜜K4ᶭE.ូឋØ¿ÀÙÚ᷈E.ÛB.¿ÀÜ᯿93.⚝Þß᷈ᨬdḄ4ᶭXᫀ98.>áGâã¸Ḅ⚝äåC.᜜K4ᶭ¥¿ÀÜ᯿A.i᷈.ᑗ◀A.-¶äåD.RM4ᶭB.᪷4ឋK4ᶭB.æçäåE.᜜K4ᶭ¥èᶭC.RMᑗ◀¥MaKC.᜜éäå4ᶭD.êëäåD.rᑐ4ᶭE.îäå89.U1CCT1N0M0,,-.Q$åð᩽ᨵE.¿ÀÜ᯿ᦔ4ᶭ9òó¯᳛õö99.ᐰ+øäåÕ|K4ᶭÜ◞Ḅú94.Uûüa.Ḅi᷈9ᨬýþᨬᔠᳮḄᜐᳮA.90%ḄA.◞■ᮤ⍡B.80%A.!"#$%&'B.◞()᯿+lOOOcGyC.70%B.3!"#$%&'45%6789ᜐD.60%C.3!"#<=&'C.◞1cm,)᯿+lOOOcGy,45%•789ᜐE.50%D.D4"$%&'D.᪷FSSD+HIJKᮤLJ90.MNOP᪷QឋS+QᶭUVWXE.ᐳZᜫ\]^◞Ḅ_JḄ`aV◤⌕Kd᷈fa␺hV4ᑡjklmnoᝰᶧd᷈fa95.ᚖ#᷈ᨬtḄuvwxE.◞2cmᡈV■᯿+{|}⌼ᡂA.ᳫA.wᳫ100.᜜▢OU4ᑡjklm◤USB.ᶭB.fC.MA.■U`aC.dD.dᙽB.K⌕SᶭD.E.¡¢C.d᷈ᑗ§¨ᑗ©ª«E.᜜£¤¥91.¬3MNOᨬ®Qᶭ⌱°D.ᑗ§µ¶V(·¸S¹96."±²ᜧV´4A.S+Qᶭº»Qᶭ¼jk#½E.¾¿ᑗ©ៜᔠB.»QᶭºUSᶭA.ᘂᖃÄÅ101.᜜▢OUVᳮÆÇᨵῳÊËÌ9᯿ᑺ:39

39E.ÏῚKD!ῳÊËÌA.30Gy/3ᕜÓ4ᕜÕ{A.)ᕜÖ×67B.40Gy/4ᕜÓ5ᕜ106.ØÙᑁOḄQᶭÛᑣB.)ᨴÖ×67C.50Gy/5ᕜÓ6ᕜA.ᔜvᙳWῚᑁS+C.ᩭáᓽÖãQᶭäVå᜜᯿+KæçQD.60Gy/6ᕜÓ7ᕜᶭD.QᶭèéÖ×E.70Gy/7ᕜÓ8ᕜB.»äVåSE.êᐸìíîïðñÖò+QᶭஹᓄýQᶭஹæçþÿᔠ102.▢⍝©ôõö÷øùOV✌⌱Qᶭ
ᶭ111.
ᶭC.ὅ
ᶭA.ḄA.
ᶭ
ᶭᙳᓄ
ᶭᡈᦗ#
ᶭB.┐&'᷈)*+ᳮ-ᳮᱯ/B.ᓄ
ᶭḄᱯ0
ᶭD.ᔜᙳ4
ᶭC.+
ᶭ56ᓄ
ᶭᡈ78
ᶭC.9:
ᶭD.
ᶭ+
ᶭE.<=>I@
D.
ᶭᶭ56ᓄ
ᶭE.ᓄ
ᶭ+
ᶭE.ᓄ
ᶭ107.KLMNᵫPQ=>)ᡂ:103.&IIbD⚠F<ᨬH
ᶭᫀ112.UVW
ᶭᐹᨵZ[ឋ]^⌴`LETcA.lm=>nopqḄA.deឋᐰWDᑗ◀+ᓄ
ᶭ=>A.-ᱥyᱥᳮᱯ/B.i
ᶭᓝkdeᐰWDB.Hassallvwᑗ◀B.-ᱥyᓄᱯ/C.pq=>C.iᓄ
ᶭ+kdeᐰWDC.-ᱥᱯ/z{ᑺoᑖ~ᱯ/ᑗ◀D.=>D.ᱥᳮᱯ/D.᜜᯿+Ὶᑁ᯿E.pq=>=>E.ᓄᱯ/E.kdeᐰWDᑗ◀+108.5
ᶭῼX[ᑖ113.<ᜐ104.▢⍝¢£ᑣ¥⊈3§ᨴᝣª«¬DA.ῼᑁ᪀¯ᩖA.±lL⚠ᐝ³4✌⌱¶·P⚗«¬B.ᨵᑭº»B.¼+½A.D⚠¾ᜐ¿ÀÁ«C.ᔜQῼ'᷈Â'C.ÃB.D⚠ᑁ¾ᜐ¿ÀÁ«ᨵÑÒÓÔᨵᑭº»
ᶭD.ᜧÊC.ᑖÄឋDD.Õ
ᶭᫀᨵᐵE.±D.D⚠ÅÆᑗ◀E.×
ᶭ114.¼<+àVᨵᔾâãḄᓰE.▢⍝=>Çᱏ109.Ù▭ᑖTXMB,TÝ⊤A.70%æ80%105.dDᑁÊ<ᨵῳ6ÌᾭÎpqA.<᜜᯿ÐB.10%æ20%B.pq

40ýþE.ÿ
B.ᨵC.125.ᾙ᷈!"#ᶭ%&⚗C.()*+,-〉ᔠ0D.(2345D.6ᑡ89:A.ᨵ<᷈=>E.@ឋBᨵᐵE.ῴEFB.GḄIᐰᑗLMN116.@P᜻RSTSUᐵḄSVW0121.6ᑡ8Ḅ#ᶭ⌱Y%Zᑡ&C.[\]T⚗`ᨵaὃcd0A.EBSVD.ᨵnojkὅ%=q<᷈A.PSAdB.AIDSSVE.ᵨnoᑗ◀tuvwB.ᑖC.8SV126.xᜮ⚠{!"#ᶭᑺ}~C.ghijklmW0D.FSVD.ᵨ!"#ᶭḄ}A.20GyE.SVE.ᑖᓄB.30Gy117.P᜻RSὅឋB@⚜ḄᐵW0(Gleason)C.40GyA.ᵱឋ122.{᪷#%ឋ!"#ᶭḄᑺ}W0D.55Gy¢65GyB.᝕ឋA.40Gy/20\/4ᕜE.80GyC.@ឋB(ᐵB.60Gy/30\/6ᕜ127.§¨{©ªᑖᓄ{W[%«2ᑖᒘD.®P᜻RSᵱឋ!"#ᶭᑺ}⌱YW0C.30Gy/10\/2ᕜE.`ᨵ¯°±A.1.5Gy/\D.50Gy/25\/5ᕜ118.²³´᯿"☢·W100cm2TD5/5ḄB.1.7Gy/\᯿"ᑺ}»0E.70Gy/35\/7ᕜC.2.0Gy/\A.6000cGy123.{ᑁghijk᳛ᨬḄ»0D.2.5Gy/\B.5000cGyA.ᑁ¿▲%ÁÂghiE.3.0Gy/\C.7000cGy▢ឋD.6500cGyB.᜜¿▲%ÁÂghi□ឋE.4000cGyC.ᑁ¿▲%ÁÂghi119.²³{!"#ᶭ〉~Æ-~»0□ឋ128.§¨{᪷#ឋ!"#ᶭᨬËÌḄA.<᷈ÇᨵÈÉjkD.᜜¿▲%ÁÂghi▢⍡Æ»0ឋB.ÎÏÐ<᷈A.ÜÝ⁐ßàḼE.┝ÙÚghi□ឋC.ÑÒÓ´ÔB.âã124.ᾙ᷈!"#ᶭD.<᷈ÕÖ²³ᕜ×Û0C.äåæ⌨E.èῚᨵghijkA.2ᕜD.⚝ëìíî120.ᐵïῴE{!"#ᶭðTÆ%&B.îâៜᔠòᓽôõE.ö[⚗-÷ø0C.4ᕜ129.§¨{ùúÚ⚠ᨵjkghiA.²³ᨵ⚣ஹ⊈ஹþញ
Ḅ᳛D.ᓽB.ᨵஹ᫱ஹஹA.10%41

41B.TP2N+M0'B.30%C.T3N-M0A.᜜᯿-+.C.40%D.T3N+M0B.ᓄ12ᶭ+.D.60%580%E.T4N-M0C.᜜᯿-+Ὶᑁ:-2ᶭE.100%135.<=>?ᗕA᧕ᨵ⚠DEFD.ᓫHῚᑁ:-2ᶭ130.IJA2ᶭḄK⌕.M'NO,QRSTUE.ᓫHV᜜᯿-A..A.10%140.IIX▢⍝[M\᷈^ᨬ`2ᶭaᫀ:B.ᓄ12ᶭB.20%A.dῚefῳhi?᯿-+ῚᑁC.:-2ᶭC.40%:-2ᶭD.jk2ᶭD.70%B.Ὶᑁ:-2ᶭ+ᓄ12ᶭE.mᐝ2ᶭE.85%C.▢⍝?᯿-+Ὶᑁ:-2ᶭ131.IJAoᙢ?ᙠᡃsᓭaᔜḕ^136.᜜▢A᯿-ῳhi?^D.Ὶᑁ:-2ᶭ+.wxᓰzᙢ?ᜮ⚠|ូឋ\᷈Ḅ⚗'ḄE.dῚeῳhi?᯿-A.10%>A.ᓫᵨᵯ᯿-B.30%>B.ᓫᵨ8MVX:-᯿-141.X⚠A〉ᔠᓫHῚᑁ:-2C.50%ᶭC.᯿-D.70%>ῳhiA.0-IaE.90%>D.ᵨXᵯᔠB.0-Ibl᯿-132.᪷|ូឋ\᷈ᨬ¢£C.0-Ib2E.¥¦§¨᯿-A.AD.0-Ha137.©ª᜜▢A⚜ḄK⌕¬B.¤AᨵE.0-IIbC.¯¤AA.\᷈°±³142.⚠Ax´µ¶·¸¹º^FIGOᑖXÝXD.DEᾙ᷈B.ÍÎA.IIaXE.ÀÁÂᾙ᷈C.ÏÐVÑÒB.IIbX133.ÃஹÄX[JA᪷2ឋ:-2ᶭD.V
ᜫÆḄK⌕Ǭ'C.IllaXE.'ᔲÔÕA.ᜮ⚠|ÈÉÇAD.IHbX138.ᝣ×\᷈ØTῚᑁ:-2ᶭB.Ê|ËÌḄÙÚ^⚗'┯ÜḄE.WaXC.Ê|ßA.àá▢⍝âᘤ143.⚠äåAḄ2ᶭÇᑣ'D.⚠|NOB.᣸èá▢⍝âᘤA..ᑗ◀KE.ëᜐNOC.ᓅîÚ▢⍝âᘤB.ï⚠A2ᶭÇᑣðwñ§134.᪷2ឋ:-2ᶭò[JAḄ•XD.ôá▢⍝âᘤC.ᓄ12ᶭ+.õᔠ〉E.ö÷Ú▢⍝âᘤD.:-2ᶭ+.A.Tr2NTI0139.nX▢⍝A^ᨬ`2ᶭaᫀE.§▢⍝A2ᶭÇᑣñ§42

42D.;cᶭᦔeC.#ᗕ144.[ᑡ⚗'©ª⚠A⚜Ḅ
D.&'()⌕¬E.fgᑁᑖiᶭjE.+,᷈7../ᶭḄ᯿2ᑺ45A.\᷈ûüᑖý149.ᑡ5⚗XᑁZA.᪷ᑺ4m9᜜᯿Ḅ〉qr!B.789:ᮤᑺ4B.dῚDEFNOC.᪷ᑺ4Ḅ1/2A.ῳt□ឋD.᪷ᑺ4Ḅ4/5C.RSᑖXxᳮÙÚE.᪷A:BCB.X
wxyz8.EFGᶭHᑖ5D.\᷈ÿ
A.ᜧᑺ4᳛ஹᑺ4᳛ஹ'ᑺ4᳛C.X⚠wx{B.LMᑺ4᳛ஹMᑺ4᳛ஹᑺ4᳛E.C.LNᑺ4᳛ஹNᑺ4᳛ஹMᑺ4᳛D.ᑖᓄIII.D.Mᑺ4᳛ஹᑺ4᳛ஹNᑺ4᳛145.ᑡ⚠◤⌕E.LNᑺ4᳛ஹᑺ4᳛ஹLMᑺ4᳛ᶭḄ!E.m}ᳮᑖW1W9.EFGᶭPQ᯿2ᢈSTᢣA.VQᑁ᯿21A.#$5O.，ᙠᶭ<⚠B.XQᑁ᯿2脓ᨬḄᜐᳮj!C.Qᐹ᯿2B.&'收ᶭஹᯠD.∑Q᯿2A.吸E.ᦱ\C.)ᜮ+#ᑗ◀10.Nᑺ4᳛EFGᶭ〉ᔠ_B.Cᢙ1ᜐᳮA.`aឋcᐭᶭD.#ᶭஹB.efᶭD.Ἥ▢⍝C.VgᜧḄ᷈E.E.$I.D.ᶭhijḄ᷈2004LA²³´µ¶ὃ¸¸⚪E.Ớ-125cᐭᶭ146.A01B0ᭆ3ᵫ5678ᶭ91.ºᶭ»¼Ḅ½j!11.ᓫ•Nop2q◤⌕tuḄTvᶇ:;?@᥅9:C.ᓫÄᶭ〉qrÅÆÇB.|ឋD.ÈᶭÉᑖូឋÂ᷈1ÊឋC.i}ឋB.BC=ᱯ9:Â᷈D.ឋE.Ëᵨ¿᜜ÍḄÎÏᶭE.`aឋC.EF9:2.ᑡ5ូឋÂ᷈ºᢙ12.,~ᑺ4qoឋjpAL☰Ð!jpLḄᐵPḄTD.Gynetro9:AÑÒA.AL=LB.E᷈B.ALLD.ÓÔ᷈D.ALL0ᑺ]!3.ÕÖᶭᐕØ<Ḅ13.Lᑖᒘ2ᶭHÙq!A.#ḄᦔA.25Gy~30GyA.ÚÛឋÜÝᑖB.ឋῃ§B.#B.30Gyb35GyC.ßàáC.D.âãäD.᯿2ᑺ4¡C.36Gyb40GyE.ᾯãäE.ᶭhi¢j4..ᶭḄæ0!14.2£¤ឋ¥ᐵḄ¦⌕§¨TD.40Gyb50GyA.çè⊈êA.᷈()Ḅ©ᨵ£¤ឋB.¢£ëìឋB.Tᔲ¬()E.50Gyb60GyC.ÈíîïðñC.᷈Ḅ®¯D.òóD.¬°◖()ᡠᓰḄ´µE.îï»ôõöçèE.¶2·¸Ḅ¹º5.mᶭí÷!15.ᶭ£¤ឋ»¼ḄT148.ᑡ5⚗XᑁZmA.;cø᷈ùú᳛A.ᶭ£¤ឋ½¾ᩭqḄÀÁᶭḄ¡Ḅ!B.;cûWùú᳛B.ᶭ£¤ឋ½Â⊈ᐵÄ⌕C.;cùúÔ]C.¤ÅÆÇᶭÈPÀÁ£¤ឋ᩽5A.¢£¤Ὶ¦§᳛D.;cÂ᷈Ḅüý᳛Ä⌕E.©ªÂ᷈þᦣD.“᠗Ì”ᢈSᑖ᪆T|ḄÏÐѼB.©ª▢⍝«¬¦§6.ᓄᔠᶭᑡ᷈E.Ò§¨ÀÁᶭ£¤Óᶭᦔ16.2£¤ឋ2ៜឋḄᐵTC.¢£E®¯°᳛A.ஹA.Õὅ×ᨵḄØᐵឋB.!B.2£¤ឋNP2ៜឋÙN43

43C.2£¤ឋNP2ៜឋÙMA,DD.üýxwnþòóD.ÚᢙÜP2ញឋNB.E.ÿᡈCTᔣ┐ᔾE.2£¤ឋÞP2ៜឋMC.36.JASTRO2000஺-2᪷17.()ßoàáḄDoã⊤åD.Ⅴ!Ὶᑁ!ឋ#ᶭᑺ&'(A.()Ḅ2£¤ឋE,UA.50Gy-55GyB.()Ḅ7Çæ·¸¹ºçè27.Uஹlmno89᯿B.60Gy-65GyC.ᙠ2Gy᯿2h()Ḅßoᑖᦪ<C.70Gv-75GyD.()ᑁᡠíḄ2£¤îᦪ☰ᦪA.[U{᯿D.80Gy-85GyE.()ßoàáḄïðpB.[U{᯿E.90Gy-95Gy18.ᙠ()ßoàáñPòóᦪô⊤(C.[U{᯿37.#3!ᶭᨬ567ᓻ9:ᜧḄ=)ᑁ©ᨵḄØᐵ2£¤ឋóᦪ£¤D.U{᯿>?@(îᦪE.U{᯿A.ABCA.Nã28.mnoῚᑁᶭ〉ᔠ¡B.#3ឋDEFGB.Dsa᷈ᨬᜧ᜜£¤¥C.#3ឋHᒹCC.DqA.^1.5cmD.ញឋ#3ឋCD.D-2B.2cmE.#3ឋHKCE.DoC.2.5cm38.ᙠ>MNOPQᐺS᜻UḄ>V19.øᑖù¢ú5᪗|P()ᕜᨬ£D.3cmWXYZ[ᙠPX\Z[ᙠ¤ḄTE.W3.5cmA.30]P50]A.G1e29.ª◞¬cda᷈Ḅ®᳛B.15],60]B.S°ᓰᡠᨵª◞a᷈ḄC.10],40]C.MA.15%D.25]P70]D.G2B.25%E.20]P40]E.GOC.35%39.ᙠS᜻UḄabPᨬcdeḄ20.ᨵD.45%f@(A.E.55%A.ᓫhijfB.30.yz´⊤ᢗ·°B.EBfC.!A.k¸NC.kfD."#$B.k¸¹D.lᜮ᷈fE.""$C.k¸NE.opf21.&ᦋ()*ᑜḄ-ᑺ/01ᜩ᯿22D.ᒃ»40.᪷qrast⊤vw⍡yzᱯ|}S4014᯿2.0Gy,789ᑖᒘ᯿<E.¼½k¾ᐵ⁚ÁÂ᜻Uᑖ'Pᓽ(A.=ᑖᒘ31.᪷ÄWH01997Æyoᑖ:A.'vw⁚ᓄvB.>?ᑖᒘA.T2N1M0IbB.ᔠvwvC.>?=ᑖᒘB.T3N1M011bC.'vw'vD.@ᑖᒘC.T2N3MoHD.⁚ᓄwᔠ'ḄQᐺS᜻E.ᜧᑖᒘD.T3N3MoHlbUw⁚ឋ'ḄS᜻U22.@ᑖᒘ᯿B0CDḄὊF/GE.T4N3M0WE.'vwvA.3500cGy32..᪷ÄWH01997Æyoᑖ041.S᜻UAnnArborᑖb(B.4000cGyN2A.⚠'nC.4500cGyA.ÏÐyzÑÒÓÔÕÖB.⚠'ID.5000cGyB.ÐyzÑÒÓÔÕÖC.ῼ£¤>¥¦'IVE.5500cGyC.ÏЪ◞!◖»ÒÓÔÕÖD.ῼ¨¤>¥¦'III23.@ᑖL᯿B0ᐰNOḄὊF/D.Ъ◞ÒÓÔÕÖE.©'IGE.ÏÐNØÒÓÔÕÖ42.ᒈῳ¬@S᜻U@®¯ᑖḄ°A.3000cGy33.yoÕÖÙÏÐÚª◞ÒÓ±B.4000cGyÔ□ឋ᳛ᨬÜḄGA.²³ᐰµ¶·¸ᵨC.5000cGyA.ÝÚÞB.²³ᐰµ¶ºᯠᵨD.6000cGyB.ÝUÞC.®¯IAᡈIIAᙳ◤¾E.7000cGyC.ÝÞD.®¯IA,ᵱឋP'vᡈQᐺ24.Rᵨᑖᒘ᯿<ḄTḄU┯WḄGD.ßÚÞv◤¾A.XYZḄE.ßÞE.ᨵB?Áὅᙳ¾B.XYḄ34.yoàᑖáWHO.1999â43.#ᶭᙠÃS᜻U!ᶭbḄÄᵨC.XYḄ[\]ឋ_`U0ãoᨵ@(
A.äåãoA.ᓄᶭÅᐰÆÇᡈÈᑖÆÇÉÊËឋ#D.>a᷈cdḄeᔠghB.æçcdoᶭwÄ'Ìᔠ!ᶭḄYÈᑖE.>a᷈cdiḄᑖjghC.yècdoB.ᐰ᯿3ÎÏ®¯wЮ¯ᮤ25.klmnoᨬqrḄstᘤvGD.éçឋo⚜■Ô>A.wnrxwnE.êåឋcdoC.Õᐰ᯿3⚜■Ô>B.yz35.ᕜìyoíîU0ï[@D.#ᶭÄ'⌕!ᶭ°±C.{|ðñḄòóGE.#ᶭc×ØÙᓄᶭD.y}A.ô᤬kᱏ44.S᜻U@c×!ៜḄូឋÜ᷈P!E.ᗕB.k÷CTòóᶭḄẆÞß|ᙠà(26.mnoḄGC.øUῃúcdòûA.ᜧ☢â·ãᑣå᯿3ᢈç44

44B.ᓄᶭèᫀᙥëìíE.ᓄᶭḄ2÷õöAE.ᔜ`Vaᙳ〉ᵨC.·îìïð᳛Ḅ³ò¨Póô!ᶭõ54.ÏᔠóᶭNHL,zMNḄ)64.ῴ^ᶭញឋhi⌕⊤l$öḄ=>?A.ᨵB(?A.ῴ^'ஹ2('D.#3÷Ḅ⌱ùB.$%oáB.ῴ^noE.#ஹᓄᶭw°çḄÌᔠ!ᶭC.ូឋÜÒḄoáC.ῴ^▢⍝ᤂ45.S᜻U᡽ᜧ᯿3åᒹü(D.p%AÜូឋD.ῴ^r(sA.ýþÈÿᕜ᡽ᜧ3-5cmE.᜜ªE.ῴ^t⊈B.ᕜ᡽ᜧ10cm55.ᜧ☢ûḄüý,ᑺÓ)65.

45A.60GyB.7ᮤ±²³´D.ᑗ▢ឋB.65GyC.µGHIJK24·E.ᕜC.70GyD.7ᮤT¸ªᜧ¹91.1978ḄWHO!"ᳮᑖ%&ḄD.75GyE.µGHIJKg20%A.I%)*ᑖᓄ,!E.81Gy83.᪷Yu»¼ᶭB.I%)&ᑖᓄ,!74.3ᑡçè᜜᯿ç5ᵨḄ᯿®A.½¾¿¿À᳛Á᳛C.I%).ᑖᓄ,!é$B.ÂÃuÄὅ`ž#¿À᳛D.I%)/0ᓄ,!A.3:Á᳛E.I%)1ᑖᓄ,!B.ê3ëìê:ëC.ÂçÄὅ`ž#¿À᳛92.ᡃ4!199256ᑖ789:ḄC.3:í;@îÁ᳛;D.ê@D.IஹIIB#ᓻÈ~`žA.I7T1N1M0E—3ìê:#¿À᳛B.II7TINO-IMO,T1-3N1M075.YZᙠð-72[ì⚜`·ÍV12YḄE.IஹIIB~`½¾#¿ÀC.III7T3N1-3M0,T1-3N3M0`3ᑡòóô᳛Á᳛D.IVa7T4N0-3M0,T1-4N3M0A.᪷Rឋᶭ84.ᑡ⚗ÉÊ᪷E.IVb7FGT,FGN,M0B.õöឋᶭYu»¼ᶭḄ〉8[93.!HὅJKL⚝NḄOC.÷RᶭA.µGHIJK24·ᔠQ;D.øùRᶭB.µGHIJKᔆ3·ÌÍᦪA.ḨSTOᔠQE.ᓄᶭÏV10·B.ḸVOᔠQ76.3ᑡ᪷RឋᶭḄú`!"#$C.7j᷈V5cmC.ᚖX≈ZOᔠQA.2(«ûü⍝ýþÿᵨD.7j᷈¸³´D.[≈OᔠQB.ᵨE,7j᷈g5cmE.\☟ᾭ_OᔠQC.⊈ᵨ85.᪷Yu┝EFG94.!`a⊤KḄcᜧXQᒹfD.ᔾᵨHIÑ8᯿ḄÓ(A.gᱥஹ⚠kgᙽஹ⚝NmnE.ᵨA.┝EF4o77.᳛"B.┝EFᐰB.⚠kgᙽஹ⚝Nmnoஹᜮq#Ḅᳮ&'(C.┝EFᐰ+Õᐰª¯+ÕC.⚝NmnoஹᜮqஹgᱥA.*᪵µD.☢sஹtuஹgᱥB.ᑖ-ឋD.┝EFᐰ+Õᐰª¯E.☢sஹtuஹ⚠kgᙽC./E.┝EF+Õª¯+ᑁ95.!Hὅᙠxᶭ7VḄញឋ{ῚஹD.01ឋ2386.×ÈØᾙ᷈ᓰᡂ~ᐰÜូឋ{}~8ᙠ᯿ᑺ7JE.45+789j᷈ḄK78.2002>?ḄUICCᑖB,┝EFGA.0.5%A.10-20GyHIJKLMNB.1%B.20-30GyA.N3C.1.5%C.30-40GyB.N2D.2%D.40-50GvC.N1E.2.5%E.50-60Gy87.ÞÈØᾙ᷈⌱àY§ᶭḄD.Ml96.!✌xᶭL70-80%Ḅg᷈tE.TLM8(ᙠxᶭL79.VBWXYḄ〉8[┯]ḄA.ᐰÜA.0.5-1(B.#ÈØáᑖâ`4j᷈B.2-3A.ᓫᮤ`ᨬᜧcW3cmC.#ÈØáᑖâ`ᜧj᷈C.4-5᜽B.ᮤg5cmD.ãÈØáᑖâ`4j᷈D.6-7C.ij᷈lm⌕ᨵpqᜧ4`rjE.ãÈØáᑖâ`ᜧj᷈E.8-9᷈ᑗ◀Yu᜜wxyzᶚw88.ϧäN`×ÈØᾙ᷈ᙠYu97.{.ᑡᒈkVD.x|7ឋᐵ10-20ᜩçèᶭ`•â☰ëìḄA.᪷E.~WYᶭ᯿íîï8ãÊB.ᡡ᪻X80.WXY᪷ឋᶭἭ[┯]A.51-53GyC.᪷¢Ḅ(B.54-56GyD.¢A.ᨵ|7ឋC.57-59GyE.ᡡ᪻X¢B.ᜧᡈᚖ'D.60-62Gy98.{£¤¥L¤g᷈᧕§¨©ª«C.ij᷈ᜧ4`ὅmᜫE.63-65Gy¬Ḅk;D.23ᑁ89.ᜮ⚠Üj᷈ᶭ§ᨬóA.®LV◣ஹLV◣¨©ªE.᧿j᷈⌕ḄôõNB.LV◣ஹ°±¨©ª81.WYu┝᯿ḄᑗA.⊈ö÷C.®LV◣ஹ°±¨©ªFL8ᙠB.øÅD.ᡡ᪻Xஹ⚠S²¨©ªA.┝Eᜮ¢£¤C.ᵯúE.LV◣ஹ⚠S²¨³ªB.¥¦§¨£¤D.VCA-IgA99.ᡡ᪻X´}~±¨©µ¶·¸C.¥¦u¨£¤E.ᳮA.¹ஹὡLஹ»ῳ½¨©ªD.¥©§¨£¤90.ᜮ⚠Üj᷈Yu◤⌕rB.°±ஹS⚠²¹¨©ªE.ªE«£¤ᶭḄ(C.°±ஹ»ῳ½±ஹ¹¨©ª82.ᑡ⚗(᪷Yu᯿ªA.GHIᒹþ᜜±²D.¹ஹ°±ஹὡL¨©ª¯Ḅ〉8[B.JKGHIÿ4E.»ῳ½.ஹS⚠²¹¨©ªA.ᑭ7ᮤg5cmC.100.¾ᡡ᪻X!᯿ÀḄÁÂÃ9:46

46Ḅ;110.ÄÅ!JK¢Æ✌⌱119.ᾯ«¬᷈8ᐰᾯxᶭL¾ÊË"A.SÌÍ⚦ÏÐÑA.ÒÓÔᶭᮤÖ×XØᔣx᜜Û᯿8ᓫÝÞ₞B.±ÌÍᗕᑗáÐÑB.ᓫâxᶭA.10-15GyC.ᑁÌÍX&äÐÑC.ᓄᶭB.20-24GyD.LÌÍᒹf⚠L¨©ªD.xᶭ+ᓄᶭC.25-29GyE.æÌÍçJ"ᮤæ,2cmE.Óæxᶭ+ÒÓÔᶭD.30-34Gy101.±!&Ḅ!êëᑖᓄìᨬ*Ḅ111.S°Z!î"ïᓰZ!E.35-39Gy;Ḅ120.&ñòóg᷈xÔᶭUõ8öxA.÷L´A.50%øឋùᐵḄno;B.ûoü´B.60%A.ូþC.L¤´C.70%B.ᕏᔢD.D.80%C.ῳE.E.90%D.ᜮ102.Ḅ✌⌱ᶭ"112.#$%&'ᶭ(ᨬᔠᳮE.,-A.&'ᶭḄᢈ0"121.ូឋ34᷈34678᷈ḄCTV;B.=0ᑗ◀A.@AXCDE᯿'ᵯHC⊡JKC.ᓫMᓄᶭᐙ᯿'A.GTV+2.5cm-3cmD.0&ᶭB.@AXCW@AᵯHCXᔠᓫB.GTV±2.5cm-3cmE.0Z&ᶭE᯿'C.GTV+1.0cm-1.5cm103.[Ḅ✌⌱ᶭ"C.@AXCW\]^_`D.GTV±1.5cm-2cmA.ᓫM&ᶭD.\]^_`E.GTV+0.5cm-1.0cmB.ᓫM=0E.\]^_`W@AᵯHC᯿'122.a[b⚠ḄᨬdᶭefKC.ᓫMᓄᶭ113.gZhiḄ#$%jᔠA.=0D.=0+ᓄᶭᶭḄkᑣ"B.&ᶭE.=0+&'ᶭA.&ᶭ+ᓄᶭC.&ᶭ+ᓄᶭ104.no#ᨬp᧕rsᑮB.u#ᓄᶭ+&ᶭ+=0D.ᓄᶭA.⚠w#xyzC.{Z&ᶭ+=|E.=|+ᓄᶭB.⚠}xyzD.=0+0&ᶭ123.IIb⚠0(ᨵῳᾭC.$xzE.=0+ᓄᶭxyzrs(᯿'E⌱D.┝#xyz114.ᜧᾯḄA.ᐰᜧE᯿'E.⚠Zxyz.A.B.ῚE᯿'105.=0ᶭᗕ〉ᔠB.᪋C.ῚWῳᾭxyz᯿'A.IILIV=0+&'jᔠᶭC.¡D.E¢r᯿'B.&ᶭ£᷈¤¥D.¦E.§¨᯿'EC.ᗕE.⚔124.ᓫMῚᜧE᯿'b⚠ḄBªᑺ¬D.ᗕ᫱®¯°115.±²³´µ¶·a¸¹ºᔾஹ±½¾E.⚠xyzrs¿ÀÁḄᾯÂKA.30Gy106.ÅÆ&'ᶭᗕ(ᓫÇᑺ¬ᨬÈḄA.ÉᾯÊᑗËÂB.40Gy"B.᪋ᜧÌÂC.50GyA.L6GyC.ᜧᾯ╢ÂD.60GyB.1.8GyD.≈ÏÂE.70GyC.2GyE.ᾯa¿Â125.&Ñᶭb⚠Ḅᨬ⌕efKD.2.5Gy116.ÓÔJᔣ&'ᶭᾯ£᷈ÖA.Ὶᑁ᯿'ØᔠÔ᜜᯿'E.3GyᵨḄ"B.ᓄᶭØᔠῚᑁ᯿'107.&ᶭᗕÛÜÝ(ᨬᨵᦔḄᶭeA.ßàá᯿'C.âHãᐭØᔠÔ᜜᯿'f"B.åa¿᯿'D.〉¨᯿'ØᔠᓄᶭA.ᢙçᶭC.0a᯿'E.Ô᜜᯿'èéB.@êëᶭD.ìáí᯿'126.■ïðHb⚠ḄBªJñKC.WòᶭE.ᑁ᯿'A.Aªóôᔣ᜜õö3cmD.=0ᑗ◀117.÷ø〉¨èé&'ᶭùúB.Aªóôᔣ᜜õö4cmE.ûüᶭý&'ᶭþÿ
ᾯC.Aᔣ᜜5cm108.T1ᓫ!ᶭḄ5$%&'ᑺ)*ᦑ,᷈Ḅ᯿/ᑺ)D.12345᜜3cm᳛8A.9℉;2345᜜4cmA.40%-50%B.CDᓄ127.ῚᑁJKLᶭ2⚠ḄAᓫNᑺ)B.50%-60%C,QRSTUC.60%-70%D.9℉QRA.200-300cGy,lOOOcGyZᑁD.70%-80%E.
30%-50%B.300-1OOOcGy,lOOOcGyZᑁE.80%-90%118.ᚖ]᷈^J_ᑖᒘ!ᶭḄC.400-1lOOcGy,lOOOcGyZᑁ109.bcd✌⌱!/LᶭḄg,᷈ᑺ)hD.500-1200cGy,lOOOcGyZᑁA.T1iDA.35-39GyE.600-1300cGy,lOOOcGyZᑁB.T2iDB.40-44Gy128.>2]j%1kᑡmn'ᘤC.T3iDC.45-50GypqrD.T4iDD.51-55GyA.>2⚠ᑁdsE.ᑖᓄtḄE.56-60GyB.>2ᑁds47

47C.▢⍝«*îḄgE.ᵨᬪᦋᗐᑺᑖ§D.ᓿxA.~ᵨ'ðÂᩞᧇ*ó~144.ᐵ0ᦔḄᭆ©ª«Ḅ`E.yᓿz!ᙠôὅröI-A.☢*z"⊈.>2⊈dḄ|}~ᨵB.*■⚓ᵨ'ðÂᩞᧇ*Ë~B.ᕜz"A.ᢣ|!ᙠùὅröqC.☢*/ᕜz"B.ᐰ᩵C.Ë~ᵨ'ðÂᩞᧇ*Ë•éD.89¯°z"C.ᝣᑁ|!ᙠùὅröqE.Z±²5Ḅᦣ¯°³zD.iᳮ|}D.Ë~ᵨ'ðÂᩞᧇ*ó~145.X?YAᑐzQµ0¶·ᵯEE.4ᵯ!ᙠùὅröqḄᑺ¸ᱯºḄ`130.2ᑁd^J*,᷈ῴcdE.Ë~ᵨ'ðÂᩞᧇ*û~A.aᨵᦔᙢ¼½Z☰¾V
¿Ḅ᯿ḄiᳮᑖhüùὅSéÎüA.Hb139.'ýþÙgᢣB.hÀḄᑺzZ{¶ÁHᵯEḄ·B.nibA.Ç]3/¢345qÿ•
L¡ML¡C.IHcdᜐᔾᦈᑺὃ
dOᜐC.Âᑖ
ᑺHᜧ)ᱯÃᙠD.Waᑺ᳛{)IᓄÄÅE.WbB.ᜐD.ÆÇᑺᢥÉÊË]TÌ131.I>2ᑁd,✌⌱ᐸ
dḄᔾᦈᑺ᳛E.Í⌕ᵨ0Ïᶭ⊤ÒᡈoḄÓ᷈³ÕA.Ὶᑁ!ᶭ"#$%&'$(#)*Ö×ᓃÙB.]᜜᯿/+ᑁᔾᦈᑺ᳛146.ᵯ¸ÏᶭÛWᐵ0▲ᐝÞß☢C.^ᑗ◀C.ᫎ᪍ᜐᑮhÀ%Ḅ$(%◣ZÆÇᑺ᳛ḄD.ᓄᶭᐸ
dḄᔾᦈᑺ᳛ḄáX┯_Ḅ`E,ᱥLᶭ$%"#&'ᜐ0ὃ
d0A.z"Ḅ$(%◣)ᜧ132.>2ᑁdᓫῚᜧ¢᜜᯿/஻B஻Ḅᔾᦈᑺ᳛ᜧᑺ)hD.ᜐB."•H$(%◣ḄL¡ÆÇA.20Gyᐸ
dḄᔾᦈᑺ᳛ᑺ᳛WâB.30Gy$%"#&'ᨬᜧᑺ5ᜐᨵC."#³z"$(%◣%◣·C.40Gyᦔ89ᑺ᳛ãḄᵯE·¶ḄᵯEᜧD.50GyE.ᜐD."•·H$(%◣ḄL¡ÆÇE.60Gyᐸ
dḄᔾᦈᑺ᳛ᑺ᳛Wâ133.¤¥¦]§¨ᘤᱯḄª«*┯Ḅ$%"#&'#)*+E.ã·)᯿)¶·ᜧ᯿gᑁᨵᦔ89ᑺ᳛ᐵA.ᮣ¯°<140.X?YA9BᦣDESC.F147.ᙠ+åW}æçèWËᔣᦣB.]±²Hᜧ)ḄIᓄDEêᑮᨬᜧC.C᜜³´µA.HḄLᜧMLᜧA.30KVX9D.¶·¨)ᵯ>¸¹ᑖº°)»¸B.HḄLᜧMN)B.4MVX9E.C஻ᗗ஻ᵯ½C.HḄLᜧMOᢝQIC.î-60ð9134.¾¢ḄTMRd.0Â⊤D.HḄLᜧRSTIᓄD.2mmAIIIVLX9A.⊤☢ᦣ/ᑺ)E.HḄLᜧᐜLᜧVN)E.ImmCuHVLX9B.ᨬᜧᑺ)º°Ḅ¨)141.WXᐵ0Z[ឋḄS]148.ᑺ᳛Ḅôip᯿`ᢣὃ5C.Ç]ᦣ/ᑺ)┯_Ḅ`Ḅᑺ᳛ᙠö)?AGy%D.ᨵᦔÉ/¸ᑺ)A.a]bᙠᜐ&010cmA.<0.4E.ʶᘤᦣ/ᑺ)
B.0.4-2135.ËÌÍrÎkḄXY/¸Ḅ¹ᑖºB.a]bᙠ᪗[ghiW10cmC.2-12°ᑺ)ZÑḄᣚÓÔÕ1
D.12-20A.ÍrÎC.ᨬᜧLḄ80%mᑁ,opE.>20B.ÍrÎÖº°Z[Ḅq5ᑺ᳛rs149.qüḄzýᚖÿC.ÍrÎ*º°*×)ᑺ᳛Ḅs
ḄD.ÍrÎ*º°*Ô¢ᜧ²D.Z[ឋtu0±3%A.ᐳ☢E.ÍrÎ*º°*Ô¢ᜧ²×)E.Z[ឋtu0±5%B.ᑗ136.TMRØh'ᨬᜧᑺ)Ù,ÚgÛk142.zZ{M|WX}•⚗C.mÜᱥᳮ)ḄSÜᱯÝÞßZpḄQᜧD.A.PDDA.gᑮᘤḄipE.ᔠ150*ᶭ!"ᶭ#$%&᧜Ḅ(B.TPRB.ᘤḄC.TARC.ᙳ᦮ᘤA.)*ᶭᢈ,-.D.SPRD.ᵯpB.)*ᶭ/0%E.SARE.☰5?ᡈg5AḄᜧ)C.ᶭᑺ2137.ᙠÌSº°ᜐ*¹ᑖº°ᑺ)äX
Y143.ᐵ0ᬪḄtᵨX┯D.3᷈ᑖ6/¸Ḅ×)Ḅåæç_Ḅ`E.7ᘤ9:᯿ᑺ2A.åæA.ᵨ0qᬪḄ᯿B.
B.ᵨᬪZ☢C.ËD⊡D.ᐜåJQC.ᵨᬪZE.Ëé⊡138.!/Lᶭ3*ᐵ1'⊡ìᘤḄíD.ᵨᬪL¡¢£48