放疗试题分章节

《放疗试题分章节》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。

⌱⚪1.ᶭḄA.ᶭB.ᶭូឋ᷈C.ᓫᶭ〉!"D.#ᶭ$ᑖូឋ᷈&'ឋ᷈E.(ᵨ᜜+Ḅ,-ᶭ2..ᑡ01ូឋ᷈ᢙ3A.456B.78᷈C.9:6D.;<᷈E.=ᑡ:63.>?ᶭ@ᐕBCDḄEA.ឋFGHB.ឋῃJC.KLMD.NOPE.ᾯOP4.=ᶭḄRSA.TU⊈WB.XYZ[ឋC.#\]^_`D.abE.]^cdeTU5.fᶭg\hA.ijk᷈lm᳛B.ijoplm᳛C.ijlm?ᮤᑺqC.᪷ᑺqḄ1/2D.᪷ᑺqḄ4/5E.᪷8ஹḄfᶭḄᶭᦔAஹXYs$J᳛Bஹij
lm᳛Cஹijk᷈lm᳛DஹᨵJEஹkg'EஹX⚪9.=ᶭḄ⌕S¢g\££#

1XY78¤¥¦᳛ijᑗ◀᳛uvḄJ©ª«g¬ஹ®⚪10ஹ¯°ᶭJ±²³C5´µ⌕¶·11ஹᑡ³᷈¸Ḅ⌕¹±®ᫀ1ஹD2ஹD3ஹB4ஹD5ஹC6ஹC7,C8ஹA9ஹABC10ஹ»¼¶·1895»½¾¿ᴊJDXÁ1896»ÂÃÄÅJDᱥ<Ç஺É᷈ᝈËÌẠ1898»ÇᶭÎÏ6Ðὅ1906»wxZ[ឋÒᐸᑖÔÕÖᡂØÙÒᐸᑖᓄÚÛᡂEØ1922»ᵨXÁᶭË1Ïs$pᗕ61928»Îܾ▭¸ÞÙßËᑺqᓫà——¿ᴊ1930»âãäᱯæçèéÙêÖËfëᶭJ±1934»᜜᯿ᑺqᑖᒘíîÙïᵨðñ1953»òᦔᭆô50»õö60÷ø&ùÁ^úᘤøÙ“ᓟþÿḄ”“ᐚ”70ᱥ“4R”70-80ᢈᢈᶭḄᭆ!11ஹ#$%ᔣ〉()ᶭ#$%ᔣ〉()ᶭ*+,Ḅ)ᶭᢈᙠ.᷈☰$12ᑮ4ᑺ6᯿Ḅ8ᐸ.᷈☰$1:᜜Ḅ<=>?ᑣ2ᑮABᑺ6Ḅ᯿஺DE)ᶭFGHᘤஹJ-60ᙳᒴMᑺ6᳛ḄOᢥ⚜%Ḅ☰Rᑺ6ᑖTḄ⌕VWᡂYᙳᒴḄMḄOḄZ[\]^Z[Ḅ_`ᡂaDEᘤᡈDEcd஺ef)ᶭef)ᶭᢈ)ᶭូឋ.᷈*.᷈i+jᐶḄlmf)ᶭcn஺ᑭᵨefqrḄᑺ6ᑖTᱯឋt:uᑺ6RvᓽBraggxyzi{.᷈|}ᕜ>?᯿6᩽<=>?ᶭḄ4.᷈Ḅ)ៜ᳛e6஺if)ᶭif)ᶭᢈ*lmf)ᶭcn஺ᵫ{ᐸYrᑺ6᷈<=>?Ḅl

2if)ᶭᵨ)ឋḄ.᷈ᐝf¢ᡈᵯf¢¤ᔠ¦ᵨ஺§ஹᱥᳮ+ஹA©⚪L«¬)ᶭtᑖa®A.ᜧᑺ6᳛ஹiᑺ6᳛ஹ°ᑺ6᳛B.±Bᑺ6᳛ஹBᑺ6᳛ஹiᑺ6᳛C.±4ᑺ6᳛ஹ4ᑺ6᳛ஹBᑺ6᳛D.Bᑺ6᳛ஹiᑺ6᳛ஹ4ᑺ6᳛E.±4ᑺ6᳛ஹiᑺ6᳛ஹ±Bᑺ6᳛2.«¬)ᶭi³᯿ᢈ*ᢣ®A.$³ᑁ᯿B.¶³ᑁ᯿C.³ᐹ᯿D.∑³᯿E.ᦱº3.4ᑺ6᳛«¬)ᶭ〉ᔠ{®A.»¼ឋ½ᐭ)ᶭB.¿_)ᶭC.$1ᜧḄ.᷈D.)ᶭÀÁḄ.᷈E.Ớ-125½ᐭ)ᶭ4.ᓫ+4Ä◤⌕ÆÇḄ*ÈᶇÊÈᶇÀḄ®A.ËÌឋB.ÍឋC.ÀÎឋD.Y%ឋE.»¼ឋ5.ÏÐᑺ6ÑÒ,ÄឋÁAL☰RÁLḄᐵÑÔÕ<Ḅ*:A.AL=LB.ALLD.AL4LE.AL>L6.J60)ᶭ×Ø>?ᔾᦈᑺ6®Aஹ×ᜧ{Ø>?BஹØ>?ᜧ{×CஹÛÜÝtÞDஹßὅá8EஹâY8×Ø>?ã7.ᔾᦈᑺ6lGyä{:Aஹ10J«Kg-lBஹ5J«Kg-lCஹ100J«Kg-lDஹ25J-Kg-1Eஹ1J-Kg-18.Äå¬æᑖ6Ḅç*®AஹÄå¬ᜧæᑖ64BஹÄå¬ᜧæᑖ6BCஹÄå¬æᑖ6ÛçDஹÄå¬æᑖ6ᐵÑÛÜÝtÞEஹÄå¬æᑖ6ᐵÑèᔠéêc%Ý9.ëῚ4í¢ᑺ6Ḅçîᑡâðᨵᐵ®

3AஹëῚᜧ°Bஹ¢í6CஹëῚᕜ>?Dஹ᯿cdEஹஹO☢1ëῚó☢Ḅôõ10.J60ᐰᢱᡠ◤ùḄú*®Aஹ10cmBஹ8cmCஹ6cmDஹ5cmEஹ4cm11.ûOḄTMR(d.0)⊤A.⊤☢ᦣᑺ6B.ᨬᜧᑺ6ḄÿC.
ᦣᑺD.ᨵᦔᑺE.ᘤᦣᑺ12.ḄX(Y)ḄᑖᑺḄᣚ!A.B."C.##$D.##%ᜧ'E.##%ᜧ'$13.TMR()*+ᨬᜧᑺ-#./012ᱥᳮḄ52ᱯ789A.PDDB.TPRC.TARD.SPRE.SAR14.ᙠ-ᜐ#ᑖᑺ>X(¥)Ḅ$Ḅ?@AA.?@B.BCC.DD.ᐜ?FGE.H15.IJᶭL#ᐵ!*+⊡OᘤḄPQ#RSḄ/A.TUᵨ*+WXᩞᧇ,\TUIᙠ]ὅ_`B.TUᵨ*+WXᩞᧇ,TUIᙠ]ὅ_`C.Tᵨ*+WXᩞᧇ,5HIᙠ]ὅ_`D.Tᵨ*+WXᩞᧇ,\TUIᙠ]ὅ_`E.Tᵨ*+WXᩞᧇ#aTUb]ὅ5Hb16.*+cd-/ᢣA.
L%Lfg`h5dᜐᔾᦈᑺ᳛lmὃd0ᜐᑺ᳛-B.
L%LfgoLfᜐ,ᐸ*+)dtḄᔾᦈᑺ᳛,l5cuvcdL5'pq*+ᑁᔾᦈᑺ᳛-C.
L%LfgoLfᜐ,ᐸ*+)dtḄᔾᦈᑺ᳛,lc5uvᜐ!mὃd0Ḅᔾᦈᑺ᳛-D.
L%LfgoLfᜐ,ᐸ*+)dtḄᔾᦈᑺ᳛,lc5uvᨬᜧᑺwᜐᨵᦔᑺ᳛-E.
L%LfgoLfᜐ,ᐸ*+)dtḄᔾᦈᑺ᳛,lc5uv5'pq*+ᑁᨵᦔᑺ᳛-17.X(Y)xᦣyzSC.F>%ᜧ'ḄDᓄ)A.>%Ḅ?ᜧA?ᜧ

4B.>%Ḅ?ᜧAB'C.>%Ḅ?ᜧA|ᢝDD.>%Ḅ?ᜧ~DᓄE.>%Ḅ?ᜧᐜ?ᜧFB'18.Qᐵ!(ឋḄHL#┯Ḅ/A.HᙠoLfᜐu!10cm
B.Hᙠ᪗(10cm
C.ᨬᜧ%LḄ80%ᑁ#bLfg(Ḅwᑺ᳛lLfgᑺ᳛Ḅ-D.(ឋ!±3%E.(ឋ!±5%19.ᐵ!ᬪ%Ḅᵨ#Q┯Ḅ/A.ᵨ!ᬪ%Ḅ᯿LB.ᵨᬪ☢*+⊡OC.ᵨᬪ*+*+⊡OD.ᵨᬪ?@E.ᵨᬪᦋᗐᑺᑖ¡20.ᐵ!oᦔ%Ḅᭆ£#RSḄ/A.☢p¤B.ᕜ¦¤C.☢p/ᕜ¦¤D.¨©¤E.Lfg`ªwḄᦣ¨©"¤o21.lX(Y)ᑐ¤-#¬!$ᵯz¯Ḅᑺ°ᱯ±Ḅ/A.ᨵᦔᙢ³´☰¶F·*+Ḅ᯿B._Ḅᑺ¤¸#\>ᵯzḄ$?@A?@C.ᑖᑺ>%ᜧ'ᱯ¹ᙠ%¸'tDᓄº»D.¼½ᑺᢥ¿ÀÁ-HÂE.Ã⌕ᵨ!Jᶭ⊤ÆᡈfḄÈ᷈"ÊËÌÍÎ22.ᵯz¯Jᶭ
Ï#ᐵ!▲ᐝÒÓ☢ᑮ_Ḅcd◣¼½ᑺ᳛ḄÖ×ḄPQ#┯Ḅ/A.¤Ḅcd◣#'%-ᜧ%Ö×ᜧB.%#>cd◣Ḅ?@#¼½ᑺ᳛GC.5%"¤cd◣◣#$ØḄᵯz-$ḄᵯzÖ×ᜧD.5$#>cd◣Ḅ?@#¼½ᑺ᳛GE.Ø$'᯿%Ö×'#$ᜧ᯿%Ö×ᜧ23.ᙠq*+L#0Ù1Ú89ÁᔣᦣyzÜᑮᨬᜧA.30KVXB.4MVXC.Ý-60YD.2mmAIHVLXE.ImmCuHVLX24.Lᑺ᳛ḄÞb᯿/ᢣmὃwḄᑺ᳛ᙠß't()GyA.<0.4B.0.4-2C.2-12D.12-20E.>2025,2%Ḅ%Lfg¤àᚖaâ¤Ḅ%()A.ᐳ☢¤ä%B.ᑗ%C.R%D.æ%E.çᔠ%

5éஹXì⚪26.ᑁஹ᜜᯿Ḅ¶¹)ïAஹᑁ᯿Ið'Bஹ᜜᯿ñᨵC·ᑖ$Üᑮ*+Cஹᑁ᯿ñ$ò5óJᶭDஹ᜜᯿tÈ᷈ᑺôᑮ_"R*+Ḅ▲ᑴEஹᑁ᯿ᑺᑖ¡ᙳᒴ27.ᬪᙠøù`ḄᵨÃ⌕/ïAஹúᑮ¸ᳮûḄ☰¶Ḅᑺᑖ¡Bஹ☢üý*+⊡OCஹþᑖDஹBC_ᑺEஹGØᑺ᳛28.LETḄÿ
:AஹᑺᐹᨵBraggBஹC,ᕜDஹEஹ!"#$ᵨ29.&'()ᑖ+,Ḅ./ᨵ0Aஹ(Ḅ12Bஹ(Ḅ3Cஹ᯿(☢6Dஹ᯿(78Eஹ9:;<=ஹ>?@A30ஹᱯCD(31ஹEFGHVL
32ஹ(HIᚆ,33ஹ(HḄKឋMஹNO⚪34ஹQRᶭTḄUV035ஹXWᑺḄᱯ036ஹ•Z3ᵯ\ḄPDDᱯ]^_`(ᱥᳮOᫀ1ஹD2ஹB3ஹB4ஹB5ஹD6ஹD7ஹE8ஹA9ஹB10ஹD11ஹC12ஹD13ஹB14ஹA15ஹB16ஹB17ஹA18ஹE19ஹD20ஹD21ஹD22ஹC23ஹA24ஹC25ஹC26ஹABDE27ஹAB28ஹABCD29ஹABCE30ஹᵯ\deḄ3fghij\ᵯ<#ᑣlhmnj\op#iᵯ\ᵫ3rstᑮv3r஺ᜐyop᝱Ḅj\{f|Z#ᜐyv3rḄᵯ\}~pḄstᑮ3rij\ᑮ᝱஺v3rḄ3rhᵯD(Ḅp#K
ᱯCD(஺31ஹiᐭ(Xᐝ\Ḅ(,᳛•Eᡠ◤⌕Ḅ1ᩞᧇᔾᦈᱥḄ,஺32ஹᙠWᜐ8y10cm+,ᡈ᪗K9:;10cm+,ᜐ#ᨬᜧ(HḄ80%£,ᑁᨬᜧஹᨬᑺ¥<¦ᑺḄ§)ᑖᦪ஺ᢥª▭ᵯ\¬ᕒ}IEC
᪗®#(HIᚆ,¯°y±3%஺33ஹᙠ80%(H£²ᑁ#³¥<¦KḄ´Ḅᑺ᳛Ḅµ¶¦·ᑺ᳛ḄµḄ)ᑖᦪK
(HḄKឋ#ᐸᜧ¹¯fº»±3%஺34ஹ1.U0জ½¾¿#ᑺᑖÀÁᙳᒴÄঝÆÇ:È#ᨬᜧᔾᦈᑺᙠ:4-5mmᜐÄঞʶËÌÍᨵÎWḄᔾᦈᑺÄটÐᔣᦣ(ঠ!"l☠஺2.V0জÖ×E&ᜧÄঝE

6⊦ÙÄঞ■Ç⌕Ûv஺35ஹজÎÜ+,ᜐ#(H¦·Ḅᑺᨬv#ᔣ(HÝÞᑺ⌲àá஺
âiᙠÁᜧ+,ᜐᑺᑖÀÁIᚆ#ᙳ᦮ᘤåæᨵçiᐸᑺᑖÀᙠ☠è⊤☢ᜐ#¦´êḄᑺᑖÀ¥vÜë஺ঝᙠ(HÝÞ▬èE&í#ᑺî<¦;<ï⌲àá#Üð☢ᵫyñ×E&ஹ®òᘤó(mn#ôÜð☢ᵫyêᔣᦣ(Ḅõmn஺ᵫñ×E&ஹ®òᘤó(öêᔣᦣ(mnḄ(HÝÞḄᑺà÷íK
ᱥᳮE&#øùᵨ80%ö20%WᑺúḄêᔣ;<⊤ûᱥᳮE&Ḅᜧ஺ঞ(Hñ×ÝÞh᜜ḄE&íḄᑺý⌕ᵫḄêᔣᦣ(ஹ®òᘤḄó(öᦣ(⌼ᡂ஺ট᜜ᜐḄᑺᵫᜮ஺36ஹᒹᑺᡂஹᑺஹX஺ᡂ!⊤☢ᑺ$!80%-85%%&,()*+Ḅ,-ᑺ./ᑮᨬᜧ3!4ᡂ''$ᑺ6"஺''ᑺ”9:;<=>?ᨵᑭ஺BஹCDᱥFஹAG⚪1.KᑖᒘCNᶭPQRA.STU>?VWTU>?ḄᦔUYZ[F\ᑖ]B.STU^_C.WTU,-D.`᯿ᑺ^bE.`Nᶭcdef2.gChiឋkᐵḄm⌕opqRA.r᷈tuḄvᨵhiឋB.qᔲxytuC.r᷈Ḅz{D.xy|◖tuᡠᓰḄE.r᷈CḄ3.Cᶭhiឋ<ḄqRA.Cᶭhiឋ>?ᩭḄB.Cᶭhiឋg⊈ᐵ⌕C.iCᶭ!hiឋ᩽⌕D.''᠗"ᢈᑖ᪆qḄE.¡¢opCᶭhiឋ4.ChiឋgCNៜឋḄᐵqRA.¤ὅ¦ᨵF§Ḅ¨ᐵឋB.Chiឋ$!CNៜឋ©$C.Chiឋ$!CNៜឋ©ªD.Cᢙ¬!CNៜឋ$E.Chiឋ!CNៜឋª

75.tu®¯°ḄDo±⊤²RA.tuḄChiឋB.tuḄ³´µ¶C.ᙠ2Gy᯿ctuḄ®¯ᑖᦪD.tuᑁᡠºḄChi»ᦪ¼☰ᦪ¾E.tu®¯°Ḅ¿À+6.ᙠtu®¯°&!ÁÂÃᦪÄ⊤tuᑁvᨵḄ¨ᐵChiឋÃᦪ¼hi»ᦪ¾:A.N±B.DsC.DqD.D-2E.Do7.%ᑖÆeÇ᪗!tuᕜÊᨬhiḄqRA.G1ËÊB.SÊC.MÊD.G2ÊE.GOÊ8.CËWTU<=>?ᨵRA.Ì,͵¶Îk̵¶B.̵¶ÎkÌ,͵¶C.ÌVÌ,͵¶D.Ì,͵¶ÏÎ̵¶ÐE.̵¶ÏÎÌ,͵¶Ð9.ÑᦋÓÔÕᑜḄ`ᑺ!×ᜩ᯿22Ù!×Ù᯿2.0Gy,ÚÁ¢ᑖᒘ᯿RA.KᑖᒘB.-ÛᑖᒘC.-ÛKᑖᒘD.=ÜᑖᒘE.ᜧᑖᒘ10.=Üᑖᒘ᯿c!ÝÞḄὊqRA.3500cGyB.4000cGyC.4500cGyD.5000cGyE.5500cGy

811.=Üᑖᒘ᯿c!ᐰáâḄὊqRA.3000cGyB.4000cGyC.5000cGyD.6000cGyE.7000cGy12.ãᵨᑖᒘ᯿ḄåḄ┯çḄqRA.:;STU<=>?ḄÌ,͵¶B.:;WTU<=>?ḄÌ,͵¶C.:;<=>?Ḅè´ឋµ¶D.,-r᷈tuḄÌyᔠêE.,-r᷈tuëḄÌᑖìê13.ᙠCNᶭ!Nᶭ,íT᧜ḄqA.ï¢NᶭᢈðñB.ï¢NᶭòóC.NᶭᑺD.r᷈ᑖÊE.<=ᘤõ᯿ᑺ14.ᐰö᯿ḄTD5/5ᑺRAஹ4000cGyBஹ3500cGyCஹ2500cGyDஹ2000cGyEஹ1500cGy15.÷§r᷈Df᳛Ḅm⌕opRAஹtuᕜÊḄfùBஹDfCஹtuúᜫ᳛DஹüýopEஹtuḄëþÿ16.400cm2
᯿ḄTD5/5ᑺAஹ4000cGyBஹ4500cGyCஹ5000cGyDஹ5500cGyEஹ6000cGy

917.᷈ᙠᯠḄ᷈ᑮ!Ḅ᷈"◤$%Aஹ60&'(Bஹ50&'(Cஹ40&'(Dஹ30&'(Eஹ20&'(18.)*+ᱥḄ-%./Aஹ1Bஹ2Cஹ3Dஹ4Eஹ519.0123456"7Aஹ1-2
"Bஹ2-3
"Cஹ3-4
"Dஹ4-8
"Eஹ8-10
"8ஹX:⚪1.<=>?⌨᠒Ḅ᷈BᶭDEF"<ᐸHᑴJKLMNᑨPQRSTNᑡJKV=:AஹXᶇḄZ[ᙽBஹXᶇ᷈Cஹ᷈]2^_`ᜫ᠒DஹbឋᙽEஹdefg2.)*+ᱥḄh34ijSᑖAஹS⌮ឋ34Bஹ01234CஹmS⌮34Dஹnᙠ1234Eஹ12343.ᑖ&᯿o᷈pqrsᨵAஹ01234Ḅ56Bஹu%vCஹᕜx"yḄuᑖz

10Dஹ᷈{-pqḄu-ᔠEஹ7[pqḄ%v4.hᶭḄ}rspqᨵAஹ⊤Bஹ⌼⊈Cஹ
DஹEஹஹ1.0ᮤ2.
3.ᮤ4.01234SLD
5.-%./6.y<ᱥᦔsRBE
ஹ⚪1ஹ▰hBᶭḄᨬᑺm"7ᑺQ᯿ᫀḄZᑣ஺2ஹe〉hBᶭ3-DCRT
j¡hBᶭḄᢈ£¤¥T¦§¨©ª«>᷈K〉¬®R¯Bᶭ¨3ஹᙠ°±᷈Ḅ᪷Bᑗ◀£oµ◤¶·hBᶭᐸ᷈¸Ḅ¹ºT¦§¨▊£ohBᶭḄZᑣ஺4ஹhᱥ¸¼ᦪ¾¿aÀÁᡈBÀÁÃÄÅƦ§᪵Ḅᱥ¸ᱯɨ5ஹ012ឋ34Ênᙠ12ឋ34ᨵ¦§mËÌÍÎÏÐḄÑᙠ஺6ஹ▊hBᶭḄÒBᶭ"7ᦔsஹÓᑴ<Ô஺7ஹhᱥ¸ḄÕÖ<Ḅᑖ×BᶭØÙ©Ḅᑖ᪆Û஺8ஹhBᶭÒᑺḄÜᡂ"7TᶭᦔḄÞ⌕àáQâᯠãᙠL-QḄZäåæᒹèᨵé&ᑖᒘᑺᑖᒘ&ᦪÒᑺëᨵr᧜Bᶭ"7ᭆîḄ¼ᦪïØ>ÍÎ஺9ஹ▊xhᓄᶭñòóyô5⛲ö%÷ᦔsḄSÓᑴ஺10ஹhBᶭø¿ùjpqញឋrsÊûx34üÞòḄᐵþQâT¦§¨11ஹÿ
ᡠḄᙠᑖᡠḄᱥᦔ஺12ஹ᷈ᑴ◤!ᡠᨵᨵ#$%&Ḅូឋ)ᓄᶭ,-./•1Ḅ23Ḅ4⌕ᱥ6789:;<13ஹ᷈=ᵯ?@AᓄᶭBᱥᡠᱥᦔḄCឋ⊤3ᨵEFGHḄᱯJ஺14ஹKLMNᶭḄBᱥᑖO)PQR஺15ஹST᷈ḄNᶭU)VWXYḄCZ[\]9^_`aḄ)
bcdᜧfgḄh᳛9jᶭklbHḄ<16ஹNᶭU)mnὅញឋCqr,)9ᔲtnὅuvwx)yzz
ḄᳮA|}஺17ஹᡠVWXY~[\Ḅh9ᔲញឋCḄfgᐵ)y
Ḅ஺18ஹᑖᒘNᶭ=_WNᶭ9᝞23NᶭḄ<19ஹKᑖᒘAᑖᒘNᶭᙠ2ஹᶭᦔCA〉⌱☢ḄᱯJ஺

1120ஹm⊤3ᨵᜧḄ,)/ᨵ=¡Ḅa/6¢)
9ᔲH£/¤¥P¦§஺21ஹ@9᷈hḄ¨7©ª)7«¬9hូឋ᷈Ḅ®7)¯9°±ូឋ᷈NᶭḄr⌕)y=/ª័§³Fᱥ6Ḅ´஺µ¶·ᱥ¸ᫀªஹAº⚪1ஹA2ஹC3ஹE4ஹB5ஹA6ஹA7,C8ஹB9ஹC10ஹCIEC12ஹB13ஹA14ஹC15ஹC16ஹB17ஹD18ஹC19ஹD¼ஹXº⚪1,ABC2ஹBDE3ஹABCD4ஹABC¼ஹ½¾´L°±¿ÀÁÂᙳ^_h3Ḅ)Äᦣ_VWXYÆᡈ᩽¡Ḅ᷈ÉÊ)ᦪÌÍW106,᝞᪷NÏᡈᓄᶭÐᐰÒÓÔ᝱஺2.cÀÁÂÖlh3Ḅ᷈ÉÊ)ᦪÌÍ106,᝞×ÏØÙ¨ᳮÚÛ஺3.°±ᡈ-Ý6lÞßḄ¨ᮤ)ᦪÌÍ2109,᝞ᒈῳãäÏᡈᑖᑗ◀ÏÓ஺4.ç᯿Ó)ᙠªé,Æᑁ%ÐᐰëìḄ[\஺5.ᙠᨵí¿îíïðñòᑮH᪵Ḅᱥᦔᡠ◤Ḅ᯿ᑺÌ©ö஺6.÷øéᱥᦔᡠ◤250kVXḄᑺÌ/÷ᡠ◤ᱥᦔᡠ◤úûḄᑺÌ஺¶ஹü¸⚪1ஹᙠýþᨬᜧ
᷈ᑴ᳛(TCP)ḄᶭᦔḄᩭᨬḄ᳛(NTCP),ᓽᨬᜧᶭ(TG)Ḅ᯿ᑺ!஺ᙠ$⌼ᡂ'()*+,-./01Ḅ23456738
᷈Ḅᑴᑺ!9ᙠ$⌼ᡂ'()*+,ញឋ/<=Ḅ234567>ᢝᶭᦔ@ABCᶭD஺2ஹ3-DCRTF8ᑺ!GᑖIᙠJKLᔣNᙳPQR(☰G)WḄXYZ[\5]@F
᷈Qᮤ_8Ḅᑴᑺ!5@FᕜWḄ'()*aᘤcᑮᨬᜧ▲fḄ■h5i[jᜧkf38ᶭḄ᯿ᢈm஺1.
᷈pqrs@tᩖḄvᒈx᪀z5᝞ᜮ⚠
᷈92.
᷈Z~/Ḅ,⌕)*ᡈᘤc5᝞55ᳫ93.
᷈X᝱$ᑣ5᝞Ὶᑁ⊤᡽ᔣḄឋ
᷈94.
᷈ᑣ▲5pqᙳᘤc5᠒5Z¡ᢙ£5ᑴ¤¥Zᐵq⌴Ḅ᯿ᑺ!5᝞ᾯ᷈52ᑡª«95.¬Ḅ®¯QᮤᡈtQᮤḄ°±ᶭ5᝞NPC96.²ឋQR5᝞⚝ᑁAVM஺3ஹ´µ1ஹ¶m·q¸ᐰº◀Ḅ¼½¾Qᮤ9ᑗÀÁÂᡈÃQᮤᕜWḄÄÅÆ«Ç஺᪷mÉ40%Ḅt᳛5ÊËᐸÅᙠ92ஹÄÅQᮤÍÎஹ⊈βÐ5ÑÒ☟Ô.ÕÖ5×Ø

12tᡈᡂÙ®¯ḄÚ஺½¾Ûᧇ3Ý5ÞÁᑴᡈt)5ßp®¯᳛ᙳNᓣ93ஹ¶máâḄãä±åaᢈmឋæç5⌼ᡂ¶mèGḄ
᷈éêᡈjë94ஹ᪷mÁìºíḄ~î8ᓻðñòóG஺mÉ/ᶭ½¾ËôḄõáæᑣ1.〉=÷ᾯ᷈ஹᜮ⚠«ஹø«ஹù⍝«ஹûª«ஹüý«ஹþ)*ᾙ᷈
஺2.2~4ᕜៜᔠ஺3,ᑺᮤᑺ45~65Gy.4.!"᦮ᒹ%&'᷈()*+,-.,/0123,-*45)67ᙠ9ᓻ;<Ḅ,/஺4ஹaGy-1
?@ABCDEḄ▽GH᧜EឋKLᩔNᦔPQRSᑺTUḄᓫWXYᦔPZ[\S]^ឋDNA_஺BGy-2
?@ABCDEḄ`DGH᧜ᢣᦪឋKLᩔNᦔPQRSᑺTUḄXWXYᦔPZ[Ḅ_ᙠcdef.ᑖhi]^jklᱥnopqrSLDḄs?]^tuHPvwT1/20.8hr,4]^97%yHPvwT1/21.4hr,6]^95%ញឋHPvwa/B?{9|8-15Gy
,ᨵ{9Ḅa?-y~HPvwa/B?{|1-5Gy
,ᨵ{9Ḅ6?஺5ஹSLDrᑺ᯿kZ[KLr᳛Ḅ᪵Ḅᑺt◞tᑖKLBC᳛ᨵᡠ9[ឋ_ᙠr▲ᑁehi]^஺1.᯿kBCDE,ḄH᧜SLDḄBᙠὅᐵ{ᜧḄDq?KL¡ᨵ{¢ḄSLD]^f£-2.ᙠLQ¥¦B?Ḅᜧ§¨ḼªᱥEḄDGH᧜SLDḄBᙠὅᐵ{ᜧḄB?KL¡ᨵ{¢ḄSLD]^f£஺PLDKLᙠ«ᑮᱯrᑺ®¦Ḅ᯿k᝞ᦋ±ᐸlBḄ³᛻)ᩩ¶.ᑖjk_ᨵefiᑮឮ^¸⊤ºKLBC᳛Ḅ9஺1.»KL᯿k¼S½⊝¿ÀÁ|¸Â"ᐰlÄÅÆÁÇcÈKLÅÆÉ◖ËᦪeÌÍᑮKLBC᳛ḄÎᓣ-2.ᑭᵨÒGᢓᑴ☟Ö~Ḅ»ÅÆKL¥×ᙠØ᷈eÌÍᑮ᪵Ù-3.ᑁopØ᷈᯿kÚÛᶇ¼ᑁÝᯠÈßàáÉ◖lÄᑖ᪆KLBC᳛ãä9-4.ᑴᱯrᑺ®¦᯿kåᜐS〉èḄ³᛻é⁐DNA«_ḄKLëfàᐭíᑖîïðᑣòóôᡂÉ◖ö÷º-åᜐSë〉lÄøùḄᩩ¶úKLᕜ~ûü,_DNAhi]^Ḅþ³᛻ᩩ¶ឮ^ö]^KLÈGᑖîBC᳛9஺6ஹ1.ᱯrÿᑺ
ᑖᒘ᯿ᦪḄᶭᫀᶭᵫᑖᒘḄஹ!"ᓄ$%⚜Ḅ'(ᱥᦔ+,-஺᝞01⚠3'ᶭ4530ᜩ7

139ᜩ:;<ᑴ᳛?,1%஺2.ᑖᒘᑺ
◞⚜ᦔ+?,B0■ᑁSLDEPLDḄFG•ᕜḄJKLMᓄG■ᙠ9OᨚQRSTḄ!U+ឋ஺3.Wᢝ⚜ᶭᦔ•⚜ᦔ+ḄYᦔᑺ
ZᶭḄ[⌲M]^_9`TYᦔᑺ
Ḅaᓣcde]fᑖghᢓᑴG•]^ᑖᑺ
dᡈk᯿ᦪn,l⊡n⚜oᑺ
┐KEU+ឋḄᑺ
qὑGWᢝᫀ⚜ᦔ+J+Ḅ(ᱥᦔ+ᑺ
nsd[ᶭḄtu⌕wnk[ᶭsdḄtu•ᜮ⚠yz{|2~3Gy/d,⊡nᑺ
0.3Gy/ᜩ}4Gy/2ᕜ~Gᜮ⚠34528ᜩT⊡nᑺ
0.61Gy/ᜩGᶭ▲3ᕜᑺ
⊡n᪥▲20Gy஺4.ᶭᦔ+KញឋU+⌕KU+ᦔ+tuw஺7ஹLᐺḄᑖᶭ:2.5~3.0GyX10,2~3ᕜᡈḄ᯿
50~60Gy஺2.Ke᠒sḄ᷈Tpot>5ᜩ]^7ᑖᒘᑺ
$ᨵᑭ᷈Ḅ:;<ᑴ£ᯠ¥kḄ¦§G3.¨Ḅᙠ©ªe«ញឋU+ᵫ᷈ḄE¬ḄU+ឋ}9®4ᕜT~¯Wᢝ⚜Ḅ:;<ᑴ᳛◤]^ᑺ
ᡈᑖᒘᑺ
±l⊡n²ᶧ¥´9Mk¦§G4.RTOGµ¶ᑖᶭᙠᜮ⚠᷈ஹ·3ஹ1⚠3Eῴ¹3ᙳ»¼½¾¿ᑖᒘᫀḄᶭᦔ¦§ᙳ¿ᫀÀ஺8ஹ1.L-QÁÂÃḄᔠᳮᎷÇ■ÈÉ⍡ËÌḄ᪶DNAᑖÎḄÏ᦮ឋÑᡠÓÔG•DNA-DSBÏᐰẚ×ØᑖÎḄÏ᦮ឋÙ[ÑÚᡠ%ᨬᐵÝḄ¦§G•ᔜß(ᱥᦔ+ᢣ᪗$âDNAQSBãäᐵὶG•ᦔ+Ḅæçèâ7Oé(ê¬ᶇḄDNAQSBᙳᦪᡂíîG••ïéḄDNARSBᦪ
ðñ
òóâôõḄᱥᳮஹᱥᓄᓄö5ç÷ðñᙠ᯿øâDNAḄù᪀ᓄöû᛻ᨵᐵḄýᵫþÿ
•ᨵᦔḄDNAQSBᦪDNAḄᓄᦔ᳛ᙠ᯿᯿Ḅ᝱!ᑴ஺2.L-Q$%&'(ᙠDNARSBᡠ*Ḅ+ᦔᐵ-.Ạ0Ḅ$1ᳮ34+Ḅ56789:;DNA-DSB
ᭆ=?@DNAQSBA᩽ᦪ+CDEFḄᐸHᱥJKLMN
OᦪᓄPQRS᳛ᨵᦔDNARSBᦪ+

14TUᎷWSLDXYᐰឋ
ᑖᒘᑺ+_`abcᨵde஺3.gᱥJhijkὃ⇋ᑮoYᐰឋpᨵqឋdeḄ$1rst%uvᩖ஺9ஹ1.yz{ᱥ|ᢓᑴgḄ᝞gD,◭.ஹAra-C2.ᙠgp{ᱥḄᕜ`ឋ☢Ḅ⊡ᵨ᝞5-Fu,.᪛vS`ᱯឋ{ᱥᵨDNAᔠᡂ`
G2-M`஺3.gᶭ_◞`᷈¢£ឋde¤abᓄKL
ᓄᶭ¥⌕§ᢝᦔ£©ªᦔ£`ᑣ|¬®¯¤de஺4.ᓄᶭ|°S±S²ᕜ`³Ḅ8ᓄvS²ᕜ`³஺5.yz{ᱥ´µ¶v☰ᡈ|¹ºµ¶Ḅ¤¶ᔠ஺Taxol,DDP¹ºµ¶¶ᓄMMC,´᷈µ¶vᦔ£☰6.»¼½¯¾¿À᷈bÁÂᙳ|ÄK⊈ƶÆ{ᱥÇ〈Évʽ¾¿ᦔ4ḄiᢵÌÆᨵᑭᩩÏ஺Ð{ᱥgᱥᦔ£Ḅ⛲1.5-Fuᱯᦔ£S`
ᢓᑴDNA-DSBḄ
CF|?ᓄ5-FuḄgdÒᦔ£஺2.CPT,HCPTS`ᱯឋ{ᱥDNAÓᡫ᪀⏘vᦔ£☰
CPT-lbpoI-DNAᔠ;DNAᑴ×
DNAØÙÚÛ
7gᨵ³Ü/Þßᵨ3.HU⌱áឋᩔãDNAᔠᡂ`
ᢓᑴDNAᓫÙÚÛḄ
G1/S`å_gᶭ³Òæ஺4.MMC´µ¶᷈vᦔ£☰஺5.DDPdÜᑁèᵫ.Ḅêᡂ
7DNAëᔠᢓᑴᐸḄ஺6.PLT(laxol)ìíᢓᑴᑺᢓG2/M`
¹ºµ¶¤¶ᔠSER1.48
dÜ@î஺10ஹញឋ¢£½*▲ᑁ᯿ᑺ+ñ6Ḅòª஺ó`½*ôᑺ+õÌöᑖᒘ᯿ᑺ+ḄᜧÂ஺

1511ஹ1.ø4ÄKùúᵨp_úᵨ:;Ḅpûî஺•:;üýþᱥᱥᦔ£Ḅÿ
ឋ
LD
,ឋ
SLD
ᙠឋ
PLD
஺•Ḅᵯᵨ"DNASSBDSBḄ
#ᑴ"%&'ḄDNADSB()*+,᳛./ᐵ஺•1DNA23ᦋ5"ῃ7᪶9ẚ;"<ὶᡈ?@Aᡂ"᧕DᡈEF"⌼ᡂH⁐AḄᶚ5஺■ᜧᑺ᯿")*OᑗQᳮ,STU")*VWXY"ᓽ[\]^\_஺•DNASSB`ab&'"%&'ḄDSBᑣd)*efឋ\Ḅᐵgឋ
஺2.1ᵨjDNAஹ)*Ḅlmnopq"`,ᡈᜫ,st)*QᱥᓄwxyzSᡈ{|Ḅ}~"t᩽ᦔ஺3.)*ᕜ^ḄᡈTU■)*ᕜ^{|#ᑴḄ᪶"O)*ᕜ^ឋ⏘CRK
,ᐸᱯḄᡂ3jO3{|Ḅ[/ឋ⊤"Y@ḄO)*ᕜ^Cyclin
Ḅ⊤•1`⌼ᡂ)*ᕜ^ᑖᐵᓱ3⊤¢ᡈᜫ,")*
£¤¥G2^¦§"⍡}©Ḅªᜫ«¬ᐭ®)*஺4.1¯)*zS°±\PCD
•.¢²³´")*
"wtp53⊤"G1^µa")*&'ᡈ¶\"PCD·,ᓄ3p53ᢓᑴ3Bcl-2,¹npᑡ⏘Caspases3⊤Ḅ{|஺•¢P53»⊤"¤¼¹TU)*ḄefᑖF½\1`P53¾¿À⊤")*&'
ᡈQ{\"PCDᡂ)*\ḄÁ⌕஺•1ÃÄ{|3Å5"¢⊤ᡈᜫ"ᡈÆ[Çᨵ{|)*ef3ḄÅ5"ÀÉូឋᓄË᝱Ḅ)*ÍAÎ¥஺•Ï᷈ḄefË᝱ஹÑÒឋஹÓÔÕᔣn'×᳛ᙳ({\ᢣᦪAI
/ᐵ஺5.1
)*Ḅ&'#ᑴ•DNA
/┯ÝḄ&'ᒹßᑗ◀&'23ᑗ◀&'BER
᪶ᵞ⏚ᑗ◀&'NER
ᐰ3ᑗ◀&'Óäᑗ◀&'┯å&'
&'t3{|ஹt⏘pq⊤Ḅ'ᩖç°"ᐸèéஹÒஹ¦§ஹᑗ

16◀ஹêᔠᡂ&'#ᑴḄìnᦔ᳛ᐵpíḄÑÒᡈᢙï஺•ð1ᱯñÑÒḄ⍡òᡈ)*Å5óᙳ«ôõᐸ&'3ᜫᡈöᜫ஺•÷øូឋÏ᷈ùúᨵ20û¹Ãü3QÅ5᝞þü"ÿ
ᨵ10᳛1/106ᑖᑣ10◤⌕1060ᑖḄ!1016ᑖ"#ᕡ1044%᪥'108
ᡂ)*ᨵ1+,"-./"013~6)ᓽ34!156᷈஺9:;<ᑴ✌ᐜ4!ᙠ6᷈Ḅ4!AB)CḼEᐵG⌕ḄHᵨ஺6.KLM4ូឋ6᷈Ḅ,■KLQ!ᱥᦔT⊤VLWXᑺZM[\ᓄᦔT^_`ᑺZᩔbᦔTḄcᔠAB஺•M[\ᓄᦔTfVgQDNAhᑡᐵjklḄஹnᔠᡈpᜫrskḄtᜫrDNAG᣸Qvwᓄᡈᢓᜫyrz⊤{Q!ᓄ|}~

176.2345᧕783ᓄᶭ"ᱥḄᢙ;ឋ
<=>?@A஺14ஹ1.CD?EFᑴHIJᵨLMḄᓄᶭ"ᱥ஺INᓄᑺ
᝞NH2ஹCTXஹIFOஹTEMஹPAMஹBCNUஹCCNUஹDTICஹBUSஹthiotepaQ,STḄNᓄUV⌼ᡂDNAᑁZ[\Ḅὶ^
ᡈDNA=`abcḄdὶ
eᢓDNAḄgh•ᕜkᱯmឋ"ᱥ
3Gonop•qᦔrsHstᓣ
〉ᵨLwᜧᑺqᓄᶭ஺IIᢙ#yz"ᱥ
᝞MTXஹ5-FUஹAra-Cஹ6-MPஹdFdcQ•^᪀|}~ᑁ#yᱥ

18G-CSF,GM-CSF,EPO15ஹ1.åஹæ)Ḅញឋ>▲éᙠ10~25%ê>ë▲éL5~10%ìíḄ>îïðᨬò?ï8
▲éóÖ5ôõ0~5%஺2.>sᙠöF~÷øù
8ᱥᦔḄï8?ᐹ÷øᱯmḄ⌱ûឋ3.ýþᶭᦔḄ78ULូឋ

ᙠ᳛Ḅឋ᷈ᑴ
ᡂᩩ!ᜧ#$ᔣ&'Ḅ()4.᷈Ḅ᩽ᐹ./ឋ01ឋ2ᦣ#45ᓽ47ᙠ89:#;<
=ᨵ?ᨎḄA▲5.CDḄEᶭGHᢈJ#KGLMNOP
᯿R#S!TUᑮ!WXY᯿R6.Zὅ\]^Ḅ_`ឋaᐸc!K⚜eឋfg஺16ஹLjDklmᔠḄ⚜■pH#qrᡈtuᐸvwញឋERyz{|}#zl~᩽ᨵᦔḄOᢝᦗ#MN!ᶭ⌕}ᨚEᶭ#ᑣK4ញឋO஺2.?#ᶭ}OTT
Ḅ#'89ᑴ᳛Ḅ#᷈Ḅa/Bᦪ¡ញឋyz
஺3.¢£Ḅ¤¥G¦ᙳ!ᢝᑖ©ᶭ#ᡠ«¬89ᑴ᳛w᳛ᙳ஺4.┐¯°Ḅyzឋ±²#j³´ᑺNdᡈ᯿R´ᦪn,f¶·ᜧᑺNDḄᶭ⊡¹#KTºᢝ»᪵Ḅ8aw½¾#ᯠ¶ᙳ·|ÀÁ°஺5.ᙠÂEᶭ°#Áyz
!vwÃ℉Ḅyzឋ±Å±²#ÆᑺN!Ç}#OTTḄXÈ¡Á°ERḄO஺17ஹ1.ញឋyz
Áyz
7É!»Ḅ
ÊË#!ᐹfÌḄᐵឋ஺2.ញឋyz
ᐹᨵÎÏᕜ°}Ñ#ᑖÒᢣᦪ³#±²ÔÕ᳛¯ÖḄᱯØ#ÙRḄwᱥᦔzᙠÂERᶭḄ»}ᓽ5]LÁyz
ᐹᨵyḄÛÜᱯØ#ERᦔz⌕ᙠ᯿RÝ&©}Þ5⊤L஺3.᯿RÝ!»
yzឋ±²àáḄ}âãä2ᜩæç28ᜩèé40ᜩêëìÊ56ᜩῴî180ᜩÁyz
ᙠÂEᶭ!vwïÃḄ±²#ᑺNᦔzᐹᨵð~ឋ஺4.ញឋyz
ÎÏñ⊤LᨵDq,D஺¯òḄᱯó#ô'õឋḄTö¯÷஺5.ញឋyz
ᨵ¯ø³Ḅa/B8-15Gy
,ù¡ᨵ¯ø³Ḅa#ᑺNú~Ḅû]ᦔzᓫýþ#'ÿ
ឋDNAᨵḄa/Bl-5Gy
,ᨵḄBᑺḄᦔNDA!ᑖ#$%
஺6.()ញឋ+,-.Ḅ⌕012ᶭ4567)8▲ᑁ᯿<ᑺ=Ḅ>.?ᑣ6•)BᑺCDEᑖᒘ᯿<ᑺḄᜧH஺7.I8J-ᑺ4LMN7)ᑺḄ᯿<ᙠᡠQRḄRᱥᦔBED
⌕ᜧᙠញឋ஺

19BED=[1+d/(Q/P)]1D[1+d/(a/B)]ᨵᦔឋ4L18ஹ1.UᑖV᯿<ᑺWH8XᢝIḄRᱥᦔZ[\᷈B᯿<ᑺᐕ_ᨵ`ᜧa.ḄDbc#ᙠdefgḄCDED\᷈Ḅh!iᑴᑺ$%2ᶭek஺2.7)ᑺḄ᯿<UB2ᶭ8Jlm8n℉pq᯿ᑖᒘ2ᶭ1.ᱯ6B2ᶭ8Jn℉lm᯿

20Î
ឋ஺7ÂញឋᨵḄa஺B᧜ᢣᦪឋᩔÈᦔᑺᡠ=ḄᨵᦔÊ᩽ÌÍ#
ឋÐᓽÒÓSSDᙠÔH8Õᨵ#t$%
஺7ÂᨵḄB஺4.rsÖ×ewdºØrsᕜg8JÚÛ`ᨵÜÝ
SSD,dᐭLßrs4ᨵàḄ½¾uḄ6ÐᓽHḄa/B஺21ஹ1.á7<¼¹âãᱥᦔAḄBCDEFGḄHIJKᐵLFGᡠ0NOPQḄDNADSBḄᙳS஺5.TUVWX>YᶭE[0ឋ\᷈஺^ஹᾯ\᷈aஹAb⚪LᜧᾯḄefghLA.ijB.᪋jC.⚩jD.mjE.⚔j2.opqrstuvwxᔾஹz{|Ḅᾯ}~A.ᾯᑗ}B.᪋ᜧ}C.ᜧᾯ╢}D.≈}E.ᾯuz}3,ᔣX>Yᶭᾯ\᷈ᵨḄA.᯿>B.uz᯿>C.u᯿>D.᯿>E.ᑁ᯿>4.〉%X>Yᶭ#(X>YᶭKoJᾯ¡¢ᑺ4ᦑ\᷈Ḅ᯿>ᑺ4oA.¥℉§¨B.©ᓄC.ª«D.¥℉ª«E.30%-50%5.ᚖ᷈®ᑖᒘXᶭḄ\᷈ᑺ4~A.35-39GyB.40-44GyC.45-50Gy

21D.51-55GyE.56-60Gy6,±0ᾯ/²᷈ᐰᾯXᶭ´oµ¶ᮤ¸ᔣX>᜜º᯿>ᓫ¼½₞4A.10-15GyB.20-24GyC.25-29GyD.30-34GyE.35-39Gy7.uv¿À'(\᷈X>YᶭuX>ÁឋÂA©ᐵḄÃÄA.ូzB.ᕏᔢC.ῳÈD.ᜮÊE.ËÌ8.ូឋÍÎ᷈EÍÎÏFG᷈ḄC7TVÐ~A.GTV+2.5cm-3cmB.GTV±2.5cm-3cmC.GTV+l.Ocm-l.5cmD.GTV±1.5cm-2cmE.GTV+0.5cm-1.0cmÑஹXb⚪9.X>ឋᾯÒÓ¶Ḅ0¶ÔᳮoÖᑡØᨵᐵAஹ¿ÀFGE¿ÀÚḄpqrÛBஹ⊈ÝÞrÛCஹOᵨßᱥ⚜■DஹâãäåæÂAEஹçèÝÞrÛ10.⚝¨êë¨Ḅ“ὶî”ᢣḄAஹᜮÊBஹñòᦋCஹôõᜮö\DஹᕏᔢEஹ÷ø0ù11ஹᐰᾯᐰÒÓ᯿>ú⌕〉ᵨLAஹᚖ᷈BஹÓÏFG᷈CஹÍÎ᷈Dஹᾯüý⊈¶Eஹ⚝þÝ᷈12ஹᾯX>rÛÿ
ḄᶭᨵAஹ⚝BஹᢙᑺCஹDஹᦋᗐᾯEஹஹ1ஹ!"᷈$(GT\/)2ஹ&ᑜ☰$(PTV))ஹ*+⚪-.ᐰᾯᐰᨵ012ᶭḄ᯿245

226ஹ789:"᷈+ᫀ—•ஹ⌱?⚪1ஹC2ஹB3ஹB4ஹB5ஹC6ஹA7ஹC8ஹA9ஹABD10ஹACD11ஹBD12ஹABCDEஹ1ஹᢣABCDEFᡈHIEFJKLMNOḄ"᷈QRᒹTUJ"᷈VWXᮤ஺2ஹᢣὃ⇋ᑮᶭB^_ᘤabcdḄXeஹ2fghV᤮jghklmḄn☟᝱Ḅqrᭆt,ᒹTCD☰$bὃ⇋ᑮv.wkᙠCD☰$ᕜQ᡽ᜧḄQ஺CTV+0.5cm)ஹ*+⚪ᐰᾯ᯿2
ᵨ}~f᯿2R•
ᵨ6-8MVX_ᢈ஺2fᒹ᦮nᜮ⚝஺vᜮ⚔4⚠஺ᐰ0᯿2
ᵨfRRᚖ᯿2ᢈRvᐰᾯfḄR‒2஺2f¡4-5cm,᪷£¤ὅ¦§¨0fᑖª2—3nfRᵯ¬fᨬᜧª20cmx20cm,f®ᶇ1.2-L5cmḄ®஺°ᕜXe®±Rᨬ²ᔣv´µ¶·f¸ᜐºஹ»ᑺNḄH¼஺½ஹ¾¿À-ஹ⌱?⚪L¾¿À✌^1ᶭ70-80%Ḅ"᷈ÃJᙠ1ᶭA.0.5-1ÄB.2-3ÄC.4-5ÄD.6-7ÄE.8-9Ä2.ᜮ⚠Å"᷈Æ◤⌕12ᶭḄÉA.ÊËÌᒹÍ᜜ÏÐB.WXÊËÌ»B4nC.ÑÒÓÏÐD.ᑗ▢ឋE.ᕜQ78×Ï3.1978ÄḄWHO¾¿ÀcᳮᑖÙ_ḄA.1ÙªÚᑖᓄÜÀB.IÙª_ᑖᓄÜÀC.1Ùª§ᑖᓄÜÀD.IÙªÝÞᓄÜÀE.1ÙªßᑖᓄÜÀ4.ᡃ⾿À1992ÄãäᑖåRæçḄÉA.IåT1N1M0B.IIåT1N0-1M0,T1-3N1M0CIIIåT3N1-3M0,T1-3N3M0D.IVaåT4N0-3M0,T1-4N3M0E.IVbåérT,érN,M05,¾¿À¤ὅmKÒ⚝78×êḄëᔠíÉA.ḸvïëᔠíB.Ḹ®ëᔠíC.ᚖð≈òëᔠíD.ó≈ëᔠíE.⚣☟ᾭöëᔠí6.¾¿ÀCD⊤KḄ)ᜧðíᒹTA.¾¿"ᱥஹ⚠Å"ᙽஹ⚝78êúûüB.⚠Å"ᙽஹ⚝78êúûüஹᜮý

23C.⚝78êúûüஹᜮýஹ¾¿"ᱥD.☢ÿஹ
ஹᱥE.☢ஹ
ஹ⚠ᙽ7.ὅᙠᶭḄញឋῚஹᙠ!"#᯿%ᑺ'()A.10-20GyB.20-30GyC.30-40GyD.40-50GyE.50-60Gy8.ᜮ⚠᷈%,ᶭ-ᨬ/⌕Ḅ123A.⊈56B.789:C.;ᵯ=D.VCA-IgAE.>ᳮ9.@◣BḄCDE◣ᑁGHḄIJᨵLAஹVIIஹVIIIM⚝IJBஹVIILIXM⚝IJCஹVIIஹVIIIஹIXஹXM⚝IJDஹIXஹXஹXIஹXIIM⚝IJEஹIXஹXஹXLXIIM⚝IJOPQIJ10.@◣ḄRSTU!"#V☢AஹWXV☢BஹYZ⚠[\]V☢Cஹ\^_V☢Dஹ`_V☢EஹᗕbcV☢11.dᨬ5eḄ-f⚝IJghḄi!"MIJAஹIIM⚝IJBஹinM⚝IJCஹIVM⚝IJDஹVM⚝IJEஹVIM⚝IJ12.jᑖᓄmnᓰpᦪḄLAஹ10%Bஹ30%Cஹ50%Dஹ70%Eஹ90%13.⚠rsbtu5eḄvᙠLAஹὡ-rsbBஹ⚠xyrsbCஹ^\rsbDஹ⚠ByrsbEஹzIJ{rsb14.CTᡈMRI125})Rouviere'srsbᜧrsbvULAஹE◣BஹCD-◣CஹCDE◣DஹXEஹ\◣15.12>ᨵM-f⚝IJgd◤ὃ⇋LAஹῚ

24BஹCஹḸDஹ@◣Eஹ⚝ᑁ16.ὅᨵᨬᜧ:iLAஹῚBஹCஹ⚝RDஹXᡈ⚣\Eஹ@◣17.ὅ◀ᱥ᜜ᨵ⚓Rᢥ92¡¢£¤ᑖ¥AஹT1BஹT2CஹT3DஹT4EஹTx18.ᙠᡃ§ᓭ©ª}Ḅ«}>᳛LAஹ5/10®BஹB¯25/10®C40/10®Dஹ60/10®Eஹ70/10®19.ὅ°}ᮤ²▲UῚ"´x⚠ᨵ3cmtursb•#ᢥ92¡¢£¤ᑖ¥LAஹIBஹncஹmDஹIVEஹᑖ¶·¸¹20.ªᑺ'᳛EºᶭG5ᵨUAஹ¼>ᓫᵨḄ¾¿Bஹ¼>᜜᯿%EÀ'᯿%CஹÁ>ÂÃ,ᶭ¾¿DஹÁ>᜜᯿%EÀ'᯿%EஹᔜÅ>21.ᙠª}ᨵ\ÆÇÈÉ"ὅÊ3ḄªᓻÌÍAஹIgA/VCAᢙÏÐÑNl:80ÒBஹÓÔឋÕCஹBὡÖDஹ᠒ឋÖEஹØÙ¢Ú22.ὅ°}ᮤ²▲UῚÛᨵ"´\⚠ஹ┝_xrsbtu஺Þß(,ᶭ©ᫀLAஹ°}ᮤᶭ⚠¾áBஹᓫâᶭCஹᶭ+ᓄᶭDஹᓫâᓄᶭEஹᓫâ¾á23.ὅJ᪷,ឋᶭE°}ᮤåæᑴÛ⚠ᶇᨵீ1cmrsb"#Þê¹\"ë,ᶭ©ᫀLAஹìᑗîïBஹðᓽ¾áCஹ┐ÌrsbóôᶭDஹᓄᶭ

25EஹBõ᜜ᦱ24.ὅ°}ᮤ²▲UῚᨵ"´x⚠rsb3cmᜧ÷tuÞß(,ᶭ©ᫀAஹ⌱ùᶭBஹᶭ⚠rsb¾á,ᶭCஹ°}ᮤ⚠rsbᙳ¾á,ᶭDஹ°}ᮤûᐝ,ᶭ⚠rsb¾á,ᶭEஹᶭ⚠rsbBõ᜜ᦱ25.ýþᶭ⚜Ḅ⌕ᨵAஹឋBஹᑖCஹᳮDஹᑺEஹஹ⚪1ஹᑡ"#$%Ḅ“'ᜧ)*”ஹ“,ᜧ-.”஺2ஹ01ὡ3⚠5ᑗ7Ḅ9஺3ஹᑡ:#$%;<Ḅ=ᶭ?@)A⍡)஺CDE#$%ᫀGஹ⌱I⚪1ஹA2ஹD3ஹE4ஹD5ஹD6ஹA7ஹB8ஹE9,D10ஹD11ஹE12ஹE13ஹB14ஹA15ஹE16ஹD17ஹD18ஹB19ஹB20ஹB21ஹA22ஹC23ஹA24ஹA25ஹBCDஹ⚪1ஹপ#Kফ⊈NবὡPভὡRমᜮUয☢XY(7)Z[Y1.#$5\ᙽ2.⚠5\ᙽ3.⚝`aXb2ஹὡ3cde⚝f7c1cm஺3d#$5Acghi஺d•ke᜜ὡm3nod஺᝞⚠qᾭ♆tᨵ\᷈vwὅyzᔣᒹ}᜜ὡm஺~dᒹ}5ᑖ$஺⚠5ᑗ7cng~nc1cmὡᚖ77~n┝cnᡈ~n┝~n~2-3cm᜜nᙠ┝ஹᜮᑁn஺3ஹಔ=ᶭ?@)1.ញឋt\U2.ញឋῚஹ$z3.ូஹᕏᔢஹஹ¡¢£¤¥¦ᐰ¨z4.=©ឋª«஺ಕ=ᶭ⍡)1.=©ឋ®2.=©ឋ¯ὡ«3.°±²4.=©ឋᾯ´µ஺¶#ῚA#h\᷈Gஹ⌱I⚪1.@·ᙠcgh¸G¹᪀Ḅ%ᵨ=ᶭᡈ¼½¾ᶭ¿Ḅ⚜ÁÂAஹc¹᪀Bஹ~¹᪀Cஹ3¹᪀Dஹ¹᪀Eஹ᜜¹᪀2.GcghÃ%ÄὅyCTÅÆcghḄ⚔iᐝ᦮yÊÄὅËÌÍᶇḸᑁÐy¸Ñ¾ᶭÁᔠᳮAஹ᪷¾ឋ=ᶭBஹ=ᶭ+ᓄᶭ

26Cஹᓄᶭ+¼½Dஹ᪷¾ឋ=ᶭ+ÍḸ¼½¾ᶭEஹ×ᐝ¾ᶭ3.cgh%Ḅ@᳛ᓰ#h%ḄA.50%B.60%C.70%D.80%E.90%4.cgh%=©¾ᶭyᨬᔠᳮḄᢈ½ÜA.ÝÞX7ß᯿©Aᵯâ7⊡ᐙ᯿©B.ÝÞX7åÝÞᵯâ7æᔠᓫ᯿©C.ÝÞX7åèéêëìD.èéêëìE.èéêëìåÝÞᵯâ7᯿©5.í3îïḄcgh%ðᔠ¾ᶭḄñᑣÜA.=ᶭ+ᓄᶭB.óôᓄᶭ+=ᶭ+¼½C.½3=ᶭ+¼½D.¼½+½=ᶭE.¼½+ᓄᶭ6.cgh%ᙠ=ᶭ3;õcghö÷øù½yᐸûᵨÜAஹüýþᳮ᪗BஹᦋᗐῚᑁឋ᛻ᶭឋCஹ᝱ᶭᶭᦔDஹᶭᨵE.ᦋᗐ!"#$%ஹ&'⚪)1.*+,Ḅ./⊤122.*+,Ḅ34ᶭ5ᑣஹᑺ8ஹ9:2;Ὶ<;=᷈'ᫀ-ஹ⌱B⚪1ஹB2ஹD3ஹD4ஹA5ஹD6ஹABCD%ஹ&'⚪1ஹপDEজ;G);H⊈ஹJᾱLஹ;MஹNOP⌨RSঝ☢VG)WXஹYᩈR[〉Sঞ^Ὶ)ᱛ`YaஹbXஹcஹῃeஹH⊈ஹf^ghᡈᱛj=ᙽRSটmḸ)omஹpqprP⌨RSঠ⚠G)uvwডᜮG)ᜮXঢὡG)▣ឋὡXণ~ᜐ)ஹஹR஺ফজ;᜜ᑁ;⍝᷈ẚᐭ;Ὶ!;ᡈ;ῚSঝ☢VG[⁐¢ᦋ£¤¥஺¦§¨q©ª[«ᑣ¬ᙢ®¯=ᙽ°XS±©²³´µ=ᙽ¶·ᡈᨵ,¸¹ᡂ»G¼½ᨵ⊈ឋᾱ¾¿JHSঞmḸ)Àm[mᳫÂÃ▲Sট⚠G)ঠ~ᜐ2ஹ1.ᶭ5ᑣ

27পḄÆ✌⌱ÈÉ4ᶭÊᑗÌ□ឋᡈ=᷈ᨵÎÏÐὃ⇋ÉᶭSফÓ±ÆᓫÕÈÉᶭᦔÖÐὃ⇋×ᔠ4ᶭᓽᐜᶭÈÉᡈᐜÈÉᶭSবT4ḄÆÜᐸÊ⚝ßஹ;àஹáâஹ≈RÃäÈÉᨵghåæçᵨᓫÕᶭᡈὶᔠᓄᶭᒹìᾭîïðñឋòóᡈ☟ᾭó3ᓄᶭõᱥS(4)÷øùúᨵ⚠GuvwḄᵨᶭ⚠Guvwὅ◀ýᳮÿᑖᓄᐸᙳᵨ⚠⚜■ឋᶭ2.ᑺজᶭ50Gy/255ᕜᶭ!◞#ᶭ$3%4ᕜ&'஺ঝ$ᶭ:55%60Gy/306ᕜঞ,-.ᮤ:12$3455%lOGyটᓫ8ᶭ60Gy/306ᕜ12$9:;70Gy/357ᕜ஺3.<2=+.?@2ᡂBᬪDEᱏ᯿HIᗕKLஹ⌱O⚪LQRSTKᨬV᧕XYᑮA.⚠[S\]^B.⚠$_\]^C.`a\]^D.┝cS\]^E.⚠\]^.2.eᶭᗕK〉ᔠhA.IllஹIVi+HjᔠeᶭB.ᶭ$k᷈mnC.oiᗕKD.ᗕ᫱q.rE.⚠\]^XY3.stHeᶭᗕKᓫᑺᨬuḄwA.1.6GyB.1.8GyC.2GyD.2.5GyE.3Gy4.ᶭ$ᗕxcyzᨬᨵᦔḄeᶭ}~wA.ᢙeᶭB.eᶭC.5eᶭD.ᑗ◀E.eᶭ5.QRSTᗕK(T1NO)Ḅeᶭ}~⌱ᵨAஹHeᶭBஹeᶭCஹᓄᶭDஹᱥeᶭEஹeᶭஹ⚪1ஹQRSTKHeᶭḄ\]^᯿Hᑣ᯿H2<஺ᗕKᫀLஹ⌱O⚪1ஹA2ஹC3ஹE4ஹD5ஹABஹ⚪প\]^᯿Hᑣজᐙᑖᒹn.ᮤ⚠Tឋ\]^&ᑣ

28ঝᓽ9NOḄ.r¡Sஹ⚠\]^TḄ⚜■ឋ᯿H¢a⚠£⚜■ឋ᯿H;ঞ¥Sஹ⚠\]^□ឋᑣ§?a⚠ஹ┝cSTᙳ⌕£⚜■ឋ᯿HফNO.rḄH2

298.·KHeᶭᨬÞþÿᓻ
ᜧḄDA.B.ឋC.ឋᒹD.ញឋឋE.ឋ9.▲ᑖᓄ"#ᐰᾯ⚜■ឋᶭEAஹ*+,ᾯ-.Ḅ/᳛Bஹ*123/4᳛Cஹ56*+,ᾯ-./᳛786123/4᳛Dஹ9:;<ᾯḄᶭEஹ*+,ᾯ-./᳛7=6*123/4᳛10."ᶭ@ABញឋឋḄᓻ◅ឋD᯿☢Gᨵᐵ7J☢GKDAஹ20cm2Bஹ50cm2Cஹ80cm2Dஹ100cm2Eஹ200cm211.LM᷈7OPᨬRḄSᶭTUKEAஹᓫWXYBஹᓄZSᶭCஹ/ᱥSᶭDஹᓫWᶭEஹYPᶭ+XY12.ᑖᓄ"]ᵨ_`ᶭa7_ᵨḄbᑺdKCAஹ40GYBஹ40-45GYCஹ50-60GYDஹ70GYEஹ65GY13.XYᑗ◀ᨵghḄIHa-bi"7OP:jḄᨬRSᶭTUKCAஹᓫWᶭBஹᓫWᓄᶭCஹᓄᶭ<ᶭDஹYPᶭ

30Eஹ/ᱥSᶭஹ⚪1ஹ"Ḅ⊤B2ஹi"ḄSᶭᑣ3ஹ"ḄSᶭᑣ"ᫀoஹ⌱⚪1ஹE2ஹE3ஹC4ஹD5ஹC6ஹC7ஹC8ஹD9,E10ஹD11ஹE12ஹC13ஹC14ஹB15ஹABCD16ஹCDஹ⚪1ஹಔ1.K¡xឋ¢஺2.¤¥3.¦⊈4.¤¨ஹ~ញ5.▲ឋ©ª«ஹ~¬ಕᐰ®¯1.°21±30%2.²³+3.´µ4.¶᷊5.ូ¹wಖ¬᷈»ᡈ½¾¿ÀÁÂÃÄḄÅ1.ÆÇÈÉoÊËÆ¥2.ῼÈÉoῼÈÉÍÎ3.ÏÐÈÉ-Ò<4.ᗕÔÈÉfÖ«ᘄØ5.⚠ÚÛÈÉ-ÜÝÞᔠ6.oàágh7.LῚ☟ᾭoLῚ☟ᾭÞᔠ8.¤å-¤æಗ᜜⊤BéêK¬᷈ë(paraneoplasticsyndrome),D¬᷈í/ᙢïðᱯòxyஹᢙ⏘ᨵᐵ,=õᨵöOP÷høùú஺1.᩷¯ᢣýᜧឋᐵ⁚¹ÿஹ2.ᑁᑖஹ(1)~ᐶᔠ(Cushingsyndrome)ফᢙᑭ!"#⊈বᵬ'!(┛⊈ஹ"*⊈(4)ឋ!ᵱឋ./013.234ᾙᔠ6478ஹᾯឋ:;ᜫ=ஹ>ᳫ◫AஹB2CDಘFᜐHIJKḄM2ஹ(1)oஹIஹnOP⌕7ᒈSTUἭWXYZ[\]^_`abᶭ஺ফIIIA\ᮤᨵjkᑗ◀ᙢX✌⌱ᒈSTUX8qr᪷b`a஺tuvᑗ◀ᨵwxyXzjkᙢᑗ◀{᷈X}~\ᮤaᶭ஺(3)HIBᓫᶭᡈὶᔠᓄᶭ஺(4)IV\]!kὊ_yX〉tᐰᓄᶭᡈHḄḄឋᶭ஺

313ஹὶᔠᓄᶭ✌⌱X`aᡈᶭ஺(1)▲Oজᐜ`aᓄᶭ¡ঝᐜᓄᶭX£ᨵ~ᶇ`aᑗ◀¡ঞᓄᶭ¦ᶭ§y¨©¡টᓄᶭ¦ᶭ«¬¨©Xᶇ`aᜐᳮஹᓄᶭ~ᶇ\ᮤḄ`¯஺ফ°±Oᓄᶭ²X3ᓄᶭᶭᦔ´µὅXj·~ᶇஹ!ஹ⌱¸⚪1.S¯»¼ᨬD¾¿ḄÀÁᘤÃÄA.ż¿ÆżB.ÇC.ÈÉD.ÊE.ᗕ2.»¼}ÌÍÎÏḄÐÑÄA.ÒÑB.ÓÔÑC.ÕÖÑD.ⅤØѦῚᑁÑE.ÚÛÑ3.Úஹܯ»¼ÝÞ᯿ÌàáâA.ãäÚÈå}æ᯿B.ãäÚÈçè᯿C.ãäÚÈéè᯿D.äÚÈçè᯿E.êåëèäÚÈ᯿4.»¼ῚᑁÌbᶭ〉ᔠì{᷈ᨬᜧ᜜ïðñA.<1.5cmB.2cmC.2.5cmD.3cmE.<3.5cm5.òìÝ!¯Ḅ»¼ó᧕ï¿Å¼Aஹ⚠¯Bஹ¯CஹÚ¯DஹܯEஹöÇ6.»¼᪷bឋᶭḄ〉÷øᒹúÜᑡÝ!⚗Aஹ7┝þÿ
BஹᜐCஹDஹXEஹ9cm7.60᝕ឋᑗ◀"⚠$%ᔠT2N1M0,ᐸ(
)*+,-$./01ᑗ◀஺345678ᶭ:;Bஹ?$@ᶭCஹᓄᶭDஹBC8ᶭEஹD8ᶭ

328.FGHᑺJḄ6@L8ᶭ7MNAஹᩔPQ᷈᜜ᕜUVWXBஹQ᷈YZCஹ[\6]᳛Dஹ_`a6ᑗ◀Eஹbcde9.a67f◞(
hijῚ☟ᾭ*no,-pqjῚ☟ᾭrᔠstᔾvw,ya6ញᦗ8ᶭ|}ᨵAஹᐜᮤ?$ᜧᑺJ@ᶭ(3-4Gy/ᜩ)7@ᶭBஹᔾᑭᙢCஹᓄᶭDஹdᱥ8ᶭEஹD8ᶭஹ⚪1ஹḄ⊤q2ஹḄ8ᶭᑣᫀGஹ⌱⚪1,A2ஹA3ஹD4ஹ5ஹC6ஹC7ஹB8ஹABCD9ஹABஹ⚪1ஹ1.<ᢝᦪ¡ᡈ2£3¤প¦§¨§Vফª7«¬বª7®¯°〉(4)ᑁ³ᱥVম§ᗕ¶Y°〉(6)ᱥ·¸¹ᶇV2.ஹ¼<প¦§vw<ᐺ¾¿ÀফᕏᔢÃÀÄÅব«¬(4)ÆᘄÈ(5)ÉÊ(6)ᐸË<(
ᡈᜐÌÍᙢ¿À஺3.¼ḄÎ<⃩аÑஹ(
ஹᜐ2ஹ1.$Òপ⚠ஹj<✌⌱@ᶭফÔ<✌⌱a6ব<@ᶭஹa6ᡈᐸËrᔠ8ᶭa2.ᐰÖ×ØYÙ¾Úᐰ᫱ÜὅᨵÞᔣὅᨵàá(
ὅ

3364.@L8ᶭëᶭᦔ°ñḄo⌕óï

346ὅ(1)AFP>200pg/LvফᐺTḄ%ឋ'(ËÌÍ⊤Üv(3)³;ÝÞAKPᡈY-GT´µᓣàv(4)áᜐᨵ´ãḄVWឋ}ᡈᨵ⊈ឋῳ?ᡈᙠῳ?äåᑮ(æçvম´ãḄé'᪗êᱥ□ឋḄ'Gᓄ஺ᓝ6íî(6ஹ⌱p⚪1.íî(]xᶭðñᵨḄ᯿|òA.x6|ᚖíB.y6|ᚖíC.xy÷|z{D.x6|÷ù|?úE.y6|÷ù|?ú2.íî(᯿|Ḅ½ýA.K5Ὺ
B.5Ὺ
C.4Ὺ
D.4Ὺ
E.3Ὺ
3.ᶭᑺA.3500cGy-4500cGyB.5000cGy-5500cGyC.5600cGy-6000cGyD.6500cGy-7000cGyE.7500cGy~8000cGy4.$%&᪷(ᶭᑺA.5500cGyB.6000cGyC.6500cGyD.7000cGyE.7500cGy5.᪷($)*ឋᶭ,-.ᵨḄᑺ1Aஹ40GYBஹ60GYCஹ50GYDஹ70GYEஹ45GY6.Dixon$-)*ឋᶭ,-᯿9:Ḅ;<ᙠ:Aஹ?@BஹA▢CCஹᙶEF⁚

35DஹHEὶᔠEஹ‒EL7.᪷($◤N9(ᶭḄ〉PQAஹR᷈TUVWXYBஹᨵ[\F]^CஹR᷈U_`aYDஹ⊈cᑁᨵ᷈᪝Eஹfᳮᓺᡄjk8.lm8cmnὅDixon's᪷($-T3N0M0,p(ᶭḄqᑣ:Aஹᶭ+ᓄᶭBஹᓄᶭCஹuvwxDஹyz(ᶭEஹMiles{|ஹf}ᑖ᪆-ᵱ-58-ᜧ⊈ஹᦪ஺‒C`a◖-⊤☢ᨵ஺fᮤᜐfᳮ1ᑖᓄ஺1.ᨬᨵ¢⌕⊡ᐙḄ¦§¨©ᗐ¦$«&¬ᕜ®ᘤ°U_±[\Fஹ²ᜐ]^2.³p(ᶭ´µ§fᳮR᷈¶·¸¹aY-«º»¼-½Ὶ[\F2¿µjk¶·3.TNMᑖvஹÀÁᑖvÂdukes'ᑖv§4.Ã}fÄ◤⌕Å9(ᶭᔩ-(ᶭÇᫀ§Éᫀ³ஹ⌱Ë⚪1ஹC2ஹB3ஹA4ஹE5ஹC6ஹA7ஹAB8ஹA|ஹf}ᑖ᪆1.CEA,½ῚCTஹῳCBºஹÎCXÏᱏஹECTEÑÒ஺2.{(ᶭR᷈©ᐰᑗ◀+[\FÖÑ஺3.T3N1M0,HIv-Dukes'Cv4.$ᶭপ,Ø1$4T6ᕜA▢CÙÚ©ᐰៜᔠ$ÜÝÞ

36ফᑺ1àÀÁfᮤ45á50Gy/4.5á5ᕜᓝ|ῴä³ஹ⌱Ë⚪1.ῴäåvfæ〉ᵨ9(ᶭA.çT1B.çT2C.çT3D.çT4E.ᔜvfæᙳ〉ᵨ2.ῴäᶭញឋëPì⌕⊤¬A.ῴäíஹíB.ῴäîïC.ῴä▢⍝ñD.ῴäòE.ῴä»⊈3.óTlஹT2avῴä$ᨬô(ᶭ{õA.᜜᯿9÷øùØúûB.ᓫýῴäᑗ◀C.᜜᯿9÷ῴäᑗ◀D.øùØúû÷ῴäᑗ◀E.᜜᯿9÷ᓄᶭ|ஹf}ᑖ᪆ᵱ-53-þÿឋᾙ⊈ஹ⚣ஹញ஺ῴῴ⊤☢ᨵᳮ"#ᑖᓄ&'()*+,஺1.ᨬᨵ.⌕⊡ᐙḄ345678ᧇ:ῴ;<ᨵ=>?@ᙽBCD5cm,EFGH᪀JKLMῚOPH@ᜧERSTᜐV&.2.TNMᑖXஹYZᑖX33.[ᶭ]3ῴ,^ᫀ`ஹ⌱b⚪1ஹE2ஹA3ஹAdஹeᑖ᪆1.BTAஹ⊈ghஹijkஹ᣸mឋn⌼5ஹMῚCTஹῳqBrஹsqXtᱏஹECTv

37xy஺2.T3N0M0,HIXz{|ᶭ+~z[ᶭ᪷[ឋῴᑗ◀z+MῚOPHxz஺ᓝូឋ᷈ஹA⚪LᙠRᐺ᜻ḄR`ᙠdᙠA.30
,50B.1560C.1040D.2570E.20402.ᙠ᜻ḄᨬkḄ"A.ᓫB.EBC.D.ᜮ᷈E.¡¢3.᪷£¤¥¦⊤§¨⍡ª7ᱯ¬᜻ᑖ®¯°ᓽ"A.OP*+®²§¨H⁚´ᓄ§B.µᔠ*+§¨OP*+·¸§C.¹*+®²§¨OP*+®²§D.H⁚´ᓄ¨µᔠ*+®²Ḅᐺ᜻¨H⁚ឋOP*+®²Ḅ᜻E.º»*+®²§¨>?*+§4,᜻AnnArborᑖX"A.¼⚠OPH¾¿ÀÁ®IIXB.¼⚠OPH¾¿ÀÁ®IXC.ῼ(ÃRÄž¿®IVXD.ῼÆÃRÄž¿®HIXE.¼ÇOPH¾¿®IX5.ᒈῳÉ᜻YZᑖXḄ~ÊA.Ë{ᐰÍÎÏÐÀᵨB.Ë{ᐰÍÎÒᯠÀᵨC.YZIAᡈ1IAXᙳ◤×D.YZIA,ᵱឋOÙH®²§ᡈᐺ§◤×E.ᨵBÚÛὅᙳÀ×

386.|ᶭᙠÝX᜻[ᶭḄÞᵨ"A.ᓄᶭßᐰàáᡈqᑖàá;âãឋ|ᶭ¨Þ®äᔠ[ᶭḄ`qᑖB.ᐰOPH᯿æçèYZ¨éYZᮤ⚜■íRC.îᐰOPH᯿æ⚜■íRD.|ᶭÞ®²⌕[ᶭ~ÊE.|ᶭïðñᓄᶭ7.᜻ï[ៜḄូឋ@᷈[ᶭḄẆõö¬ᙠ÷"A.ᜧ☢øÏhᑣú᯿æᢈzB.ᓄᶭüᫀ᝞þÿC.
᳛ḄLᶭḄD.Ḅ⌱E.ஹᓄᶭḄᔠᶭ8.᜻!"᡽ᜧ᯿&ᒹ()A.*+,-ᕜ/᡽ᜧ3-5cmB.*+,-ᕜ/᡽ᜧ10cmC.ᐰ2345234᯿D.ᧅ7&E.8ᧅ9&9.ᧅ9&᯿Ḅ;<=)A.ឋ?@B.ABCឋC.DEFG᷈D.IJKLMNE.ᵬPQKLR10.NHLḄSTᱯV,XYḄ=)A.Zᜧ[ᦪI]234ᑁB._`ᢥ23bcᔣ⌲fgᦣi᩽k=''mn"pqC.STᑖ

3912.ὁNHLḄSTᱯVi┯Ḅ=A.¡;<"¢[B.ῼR"[C."ᳮ¥¦§¨©ឋᜧª«¦[D.⚜ux¬E.ᓄᶭὊ®ឋ¬i_`
¯°ᓄᶭ13.NHLḄ☢⚠ὶᔠ&¯⌕〉ᵨF]A.·¸ῚḄNK/T23᷈B.¹᪷Ḅ23᷈C.»⚠Ḅ¼½23᷈D.ᵬPQḄ23᷈E.¾¿Ḅ23᷈14.ÀÁ;<ÂូឋNHLᐰÄᶭḄᑺÆ_`~A.lOcGy/5ஹ10-155B.50cGy/5ஹ10-155C.lOcGy/5ஹ5-105D.100cGyஹ15ឋ᯿E.᪷Ç"ÈὊ®ÉÊËÌ15.F]ḄNHLᶭxᔠᓄᶭ=Í~A.Î,-NHLᶭx
ÏÐB.ᵫ]ᕜ/ḄÒ⌕ᘤÔ▲ᑴiᶭ
᧕Øᑮ᪷ÆC."ᳮ¥¦x~ÚÂូឋi᧕ῳῚgᦣD.ᶭÜÝᜧi"È
᧕Ὂ®E.ᓄᶭḄCÞÜÝ16.ᔠᶭNHL,
XYḄ=A.ᨵBPB.;<"ÈC.ូឋÂÚḄ"ÈD.{<ÂូឋE.4᜜®17.á᜻!23᷈ᶭḄ᪷ᑺÆ~)Aஹ45-50GyBஹ55-60GyCஹ35-40GyDஹ30-35GyEஹ25-30Gy

4018.Iஹn<᜻!"iῼ»¦âᶭ¡ᵨᐰ234᯿iᐸ/ᒹ(Aஹᧅ9&Bஹ᎔æ&Cஹᧅ9&+Dஹᧅ9&+᎔æ&Eஹᧅ9&+ῳ¯èᾭê23419.IஹII

41Eஹᐰῳ᯿24.MNOPឋNHL,/:MNᑗ◀TᶭB᯿ᒹAஹOP/:;BஹOP/:;+;U!"VW;CஹOP/:+XMNDஹ;U!"VW;+XMNEஹ;U!"VW;25.IஹII,᜻./AᶭYᓄᶭZᔠ1ᶭḄ〉]B^⌕4AஹᨵB]aBஹb◞ᜧdᙽCஹfg!"#;h3iDஹ/ᳮ4!"kl4^mEஹ⊈o50mm/q26.IIIஹIVrsូឋ?,᜻.!"᷈Aᐰu᯿Bvᑺ94:Aஹ8GyBஹ6GyCஹ1.5-2GyDஹ2.5-3GyEஹ3.5-4Gy27.IஹIIῼm,᜻./Aᧅ{E᯿B᯿EḄ|}ᙠ:Aஹῼ☢Bஹᒃ☢Cஹ10Dஹ12Eஹ8ஹX⚪1.?,᜻.!"᷈▭⚜TᢣᦪᑖḄᢣ᪗ᒹᑡAஹ/ᳮᑖBஹCஹᑖDஹᑖEஹ#᜜2.“Y”E᯿ᒹḄ^⌕!"#;ᨵAஹ!"#Bஹῳ^¡ᾭ£!"#Cஹ¤¥⊈£!"#;

42Dஹ¤ῳ¦§¦¨©;!"#Eஹb◞!"#3.,᜻./Aᧅ{E᯿BCª«ᢱḄᨵAஹᗕBஹ®¯ᜮCஹ¤±Dஹ²LEஹ³4.IIIஹIV?,᜻.!"᷈Ḅ1ᶭ´ᓄᶭ4^B1ᶭḄAᵨµAஹX¶ᶇ/:FᶭBஹXᶭ¸ᜧᙽ/:;ᶭCஹAᐰ!"#᯿Dஹ=ᐰ!"#᯿Eஹᐰu᯿5.ᧅ{E᯿ᒹḄ!";ᨵAஹ¤⚠!"#;Bஹ¤¹!"#;Cஹᐰb◞!"#;Dஹ¤±º!"#;Eஹ¤»¼!"#¨ஹ½¾¿À1ஹ“B”]a2ஹÁ!"&Â$%&BWaldegezsringÃÄஹÅÆ⚪1ஹOPÈÁ!"&ḄNHLḄ1ᶭ஺2ஹ?Êᩲ.!"᷈ḄÌÍ⊤ÏḄᱯÑÒូឋ!"᷈ÆᫀÔஹAm⚪1ஹA2ஹB3ஹD4ஹA5ஹA6ஹA7ஹC8ஹC9ஹC10ஹB11ஹA12ஹE13ஹB14ஹA15ஹC16ஹD17ஹA18ஹD19ஹB20ஹB21ஹB22ஹB23ஹE24ஹD25ஹB26ஹC27ஹCÕஹXm⚪1ஹBCDE2ஹBCD3ஹABCD4ஹAB5ஹABCD¨ஹ½¾¿À

431ஹÌÍÖ×ØOPÙ38࠷´BÛÜ3ᜩÞßàÞ×ØOáâãÂäᑁáâãᜧÈ10%
æ4“B”]a஺2ஹµᵫÁῚஹᡡ᪻ஹê᪷ஹìÁ´íîï☢!"ᡠñḄ&ò;UÄஹÅÆ⚪1ஹজ᯿⚝õஹÁῚஹᡡ᪻ஹê᪷ஹíîï☢ஹìõஹᐰ⚠┝¯!"#VW;஺ঝ᯿EḄøù☢⚠ὶᔠE+û⚠┝¯;Ḅ⚠¸ᑗüEBýfgᑮῚÿ
஺•☢⚠ὶᔠḝ⁚᜜ὡḄ᜜Ḯ᜜ὡ"#Ḅ$%᪷'⚠()*+,-.ᵬ012ᑗ456$
᜜Ḯ72cmᜐᚖ:ᔣ%ᙠ%=2%2cm>ᔣ
?@☢⚠ὶᔠᙠ"A஺7BCD᪋()ᒹᙠᑁ஺•⚠
ᑗ☢⚠ὶᔠ⊖I%J2ᑗ4%2cmᔣKLᔜ4cm,┝2%2cmA⊖IK@O┝ᐵ⁚2ஹ✌S⊤UVᨵ᜜XYḄ⊤U$◀[\ូឋ᜜S_`\ᙳbc$de()⍝g/ᡈ⊈⍝ᔣklᡈmᜐ᡽ᦣ$pqr▲t,u()vwypz$B{0bHDq|$ᐰ~⊦|஺ᓝ,ஹA⚪1,"XYg@S᳛bḄXᳮA.᪵B.ᑖឋC.D.ឋE.2.2002¡ḄUICCᑖ¢"┝2()£¤+¥A.N3B.N2C.N1D.MlE.+3,¦¢§¨©Ḅ〉«{┯Ḅ

44A.ᓫSXᮤᨬᜧ³43cmB.Xᮤ´5cmC.µ᷈A·⌕ᨵ¹ºᜧ»µ᷈ᑗ◀©7᜜¼½¾¿ᶚ¼D.½ÁឋÂXE.XÃÄÅI§©Æᶭ4.§¨©É᪷ÆឋCᶭἭË{"┯ḄA.ᨵÁឋÂXB.ᜧÌᡈ%ᚖÌC.̵᷈ᜧKὅηÏᜫÑD.ᑁE.᧿vµ᷈5.§©7ÓÔÕÖ┝᯿ØÙḄᑗ«ᙠA.┝2ᜮ%56B.ÛÜ
Ý56C.ÛÜ7Ý56D.ÛÞ
Ý56E.J2ß566,%ᑡá⚗Ô᪷Æ©7᯿ØJãḄ〉«{A.Sᮤ5cmB.SᮤwäåC.Öæ()£¤24uD.SᮤçgJᜧèE.Öæ()£¤20%7.᪷Æ©7éêCᶭA.ëìrí᳛Éî᳛B.ïð7ñὅòìrí᳛Éî᳛C.ïð
ñὅòìrí᳛Éî᳛D.IஹII¢ᓻôXÃòìrí᳛E.IஹII¢XÃëìrí᳛Éî᳛8,%ᑡá⚗Ôõt᪷Æ©7éêCᶭḄ〉«{A.Öæ()£¤24uB.Öæ()£¤1-3uöᦪøீ10uC.Sµ᷈5cmD.Sµ᷈çgäåE.Sµ᷈5cm9,᪷Æ©7┝2v()úS«᯿ØḄy

45A.┝2vB.┝2ᐰvC.┝2ᐰv+ü@ᐰJã+ü@ÖæD.┝2ᐰv+ü@ᐰJãE.┝2v+ü@Jã+ᑁv10.¦¢ý§¨©ÙÖæ()ḄᜐᳮdVýþ¥AஹIôÿᒈBஹi+n
ᒈCஹ1+11+10
ᒈDஹᒈEஹm
ᒈ11.ᒈIஹII
ᓫᨵm
Ḅ᳛:Aஹ10%Bஹ15%Cஹ5%Dஹ3%Eஹ20%12.᪷!ᶭὅ$%&!ᶭ'ᐰ$%᯿*ᑺ,-.AஹOGyBஹ40GyCஹ5OGyDஹ50Gy0ᮤ234᯿10-20GyEஹ70Gy13.᯿*ᑁ7'ᑺ,8ὃ:;ᙠ=>.Aஹ1cmBஹ3cmCஹ7cmDஹ5cmEஹ10cm14.-?@Aᑁ7᯿*ḄBᵨ᯿*EFᒹH.AஹIJK1-5LMBஹIJK1-3LMCஹIJK3-5LMDஹNJK1-3LMEஹIJK1-5LMOJK1-3LMPஹXQ⚪

461.STU!ᓄᶭWᔠᶭḄ〉Z[-.Aஹ\᷈W᝕mBஹ\ᙽᙠab2Cஹᨵcdᾭfឋ0hDஹ\᷈ᜧjkᜧjlmᔠ〉Eஹ0nop2.qr᪷ᓄᶭὅs◤!ᶭḄ〉Z[u⌕ᨵ.Aஹdᮤ-TLT20wBஹ1-3xCஹy4xDஹdᮤ-T30wEஹT30w+24x3.᪷$%᯿*'{ᵨḄ᯿*ᢈᨵ.Aஹᵯ~᯿*Bஹ60ᑗ᯿*CஹXᑗ᯿*DஹXᚖ᯿*EஹXᑗ᯿*ஹ⚪1ஹḄ!ᶭdᑣ2ஹᔜ᯿*ḄEᑺ,஺ᫀ.ஹAQ⚪1ஹE2ஹA3ஹB4ஹA5ஹB6ஹD7ஹE8ஹC9ஹC10ஹB11ஹD12ஹD13ஹB14ஹBPஹXQ⚪1ஹADE2ஹCDE3ஹABDஹ⚪1ஹ1.1-nrSឋT4᪷ឋ!ᶭCT,!ᶭᑜ᯿*ᑺ,45—50Gy,ᑗ⊡,20Gy,2◤᯿*ὅ60—70Gy2.᪷ᡈᦋ!ᶭ1▢ឋT1¢T20w£▲\᷈!ᶭᑁ£▲ᡈab2\᷈᯿*ᑁ2ᑺ,50Gyফ¦r□ឋ᯿*$%U⚔┝ª«2ᑁ2ᑺ,50~60Gy

47ব¦r!ᶭOUICCᑖraWBᡈNr\᷈ZkTUᓄᶭᔠ¯ᶭ¯°ᡈ@,T!ᶭ4
¦rªὅ!ᶭ±²ᦔ´µ஺2ஹপ┝ª«2.জ¸«¹:⚠>1/3;>¹.┝ª>».ᑁ¹.$┝ᐵ⁚᜜¹.¿ªᜮ»஺ঝᑺ,.50Gy,X+ᵯ~ফ2.জ¸>¹.KP°LÂÃᑁ¹.$ᜧÄ᜜»᜜¹.Å▎Ä°»஺ঝᑺ,.50Gy,X*3
ᑁ2.জ¸>¹.KÇL°ᑁ¹.Èa᜜¹.ÈaÉJ5¢6cm஺ঝᑺ,.50Gy,ᵯ~ভ$%50Gy,ᵯ~/ᑗᓝÇÍ
Î\᷈—AQ⚪.1.Í
Îᾙ᷈Ḅ᪗Ñ⌱ÓឋᶭÔAÕÖᑗ◀B!ᶭCᓄᶭDÕÖᑗ◀ὶᔠ!ᶭEÕÖᑗ◀ὶᔠᓄᶭ2.Í
Îᾙ᷈ᨬÕÖZᵨḄkTὶᔠḄ!ᶭÚÛÔA°ᓄᶭBaᓄᶭCᓄᶭD
ÎMÜÝÞ᯿*E°4!ᶭ

483.Í
Îᾙ᷈!ᶭZᙠTᜩàáA5-10B10-20C20-30D12xᨴE3xᨴ4.Í
Îᾙ᷈ÕÖᑗ◀ὶᔠᓄᶭḄ5ãä᳛å-A10-30%B30-50%C50-70%D60-80%E70-90%5.Í
Îᾙ᷈æ᯿*Ḅᑺ,-GyA30B40C50D55E606.Í
Îᾙ᷈!ᶭḄç☰ÈéḄ᯿*,êZëGyA45-50B50-55C55-60D60-62E65-707.Í
Îᾙ᷈
ÎMìíîᐸ〉A
ÎðëᑖçB
ÎðaᑖçC
ÎðᑖçD&Eñᜐᮤ8.Í
Îᾙ᷈
ÎMìíê⌱Ó᷈óôàcmA0.5-1.0B1.0-1.5C1.5-2.0D2.0-2.5E2.5-3.09.G1Uõv5cmḄÍ
Î\᷈!ᶭ*ZᒹH᷈ó᜜cmḄEA5B5-7C5-10D7-10E1010.Í
Î\᷈°!ᶭᕜF÷¯TA1-2B2-4C3-4D3-5

49E4-511.Í
Î\᷈
ÎMìíḄ!*ᑺ,-GyA15-20B20-25C25-30D30-35E35-4012.Í
Î\᷈
ÎMìíḄ〉ø'MÔᜩA2-3B4-5C5-10D10-15E15-2013.G3Uõ
10cmḄÍ
Î\᷈!ᶭ*ZᒹH᷈ó᜜cmḄEA5B5-10C5-15D10-15E10-2014.G2Uõᙠ5-10cmḄÍ
Î\᷈!ᶭ*ZᒹH᷈ó᜜cmḄEA5B5-10C5-15D10-15E10-20PBQ⚪.A᷈ó᜜5cmB᷈ó᜜5-10cmC᷈ó᜜᜜15cm15.G3Uõ
10cmḄÍ
Î\᷈!ᶭ*Zᙠ16.G2Uõᙠ5-10cmḄÍ
Î\᷈!ᶭ*Zᙠ17.G1Uõv5cmḄÍ
Î\᷈!ᶭ*Zᙠ(AEBRTBIOBRTCCFRDHFART18.{úᑖᒘ!*ᶭÔ19.aÜÝÞ!*ᶭÔ20.4üýᑖᒘ!*ᶭÔ21.È᜜᯿*ÔAG1BG2

50CG322.ëþូឋ
23.ូឋ
24.ូឋ
A20-25GyB50GyC60-62Gy25.ᾙ᷈᯿Ḅᑺ26.ᾙ᷈Ḅᑺ27.ᾙ᷈ᶭḄ☰Ḅ᯿ᑺC⚪"28.#$ᾙ᷈%&'ᑗ)*〉,-.ᶭA/ᔣᑗ)B1ᔣᑗ)C2ὅᙳ〉,D2ὅᙳ5〉,29.6᷈7⌱9Ḅ:A60CoB6MVᐝᵨḄ:A,92IrB,25IC2ὅᙳ=D2ὅᙳ5=31.#ᑡ%&CᶭDE=Fᾙ᷈ḄG$ᡂI᳛AKᶭBKᓄᶭC2ὅᙳ=D2ὅᙳ5=MX⚪"32.6᷈KᶭḄNOᨵAQ6᷈RSTF6᷈ᑗ◀᳛B5VW-.ᓄᶭCXY6᷈Z[Ḅ\]D^_`a&ᡈῃdZ[Ḅe\f᳛E^_ᕜhijklᮤ33.nᑡᐵpᾙ᷈ḄqErsḄ

51A5t%&uvᙳwG$B#$ᶭx_wGᶇ2-3cmḄᩩ{|5}᯿C#$ᶭ5w/~#$/D#$ᶭ=/~#$/E$Ḅஹ6ஹᐵ⁚ஹᢚG$Ḅẚ34.#ᑡᐵp6᷈ḄqErsḄ
A|w>-.⚜■ឋᶭB|5>⚜■ឋᶭCwᐰᐵ⁚Ὶ᯿D=᯿᦮¡¢Ew᯿᦮¡¢35.#ᑡ£¤
6᷈Ḅ¥¦§A¨)5ៜB¨)ª«C¬®¨D¯°±²E³ᢓᑴ36.6᷈ᶭḄ¥¦§ᨵA¨)5ៜBª«ᾱC·¸¹⍝D»¼Eឋᢚ37.6᷈ᓫ¾ᶭ〉pA6᷈¿E'ᑗ◀B6᷈ÀᜧCᨵ'ἭçDlÄÅÆ'EǦ38.6᷈ᶭḄ〉w§ᨵA6᷈ÈᜧBᨵÉᶇlᮤCÊË'=Ì5ÍÎD`aǦTᨵǦÏᔣὅEYᑖ6᷈39.6᷈>ᵨḄᶭDÑᨵAKᶭBᶭCᶭDᓫ¾ᶭE40.ᜧ6᷈ஹᑖḄ$6᷈T#ᑡ%&DE=FG$ᡂI᳛AKᓄᶭBKᶭCKᓄᶭ

52DKᶭὶᔠÔÕCᶭEKÖCᶭ×Ø⚪"41ஹÙÚ6᷈KCᶭḄNOஹ〉w§Û>᯿ᑺ஺42ஹÙÚ6᷈ᓫ¾CᶭḄ᯿hÛÞß᯿ḄàNá⚗஺1ஹD2ஹC3ஹB4ஹD5ஹC6ஹD7ஹC8ஹC9ஹA10ஹBIkB12ஹB13ஹD14ஹB15>C16ஹB17ஹA18ஹC19ஹB20ஹD21ஹA22ஹA23ஹB24ஹC25ஹB26ஹA27ஹC28ஹB29ஹC30ஹC31ஹC32ஹACDE33ஹBCE34ஹBCE35ஹABCD36ஹABCDE37ஹACD38ஹBCD39^ABCDE40^ABCDᓝ÷ø⚠úஹ⌱9⚪1A⚪1ஹø⚠úᑺ᳛û᯿,ýÈាÿᑺ
▭ὃ⇋A..᜜᯿B40-50GyB.Aᑺ
ᒹ᜜᯿70-80GyC.᜜᯿!"#ᐰ%ᑺ
,Ὶᑁ)
D.┐,-./0,12,3,4᦮ᑺ
E.78ᔜ⚗2ஹ=⚠?@ᶭB⌱DA,BEFᑺ
Gὃ,HIᑖ2KLA.AKLM◖82cm,Q=RS᜜2cm,BᙠA.UVWXᔣ᜜3cmB.=⚠᜜[8\2cm,R]^_2cm`AXaᔣ᜜3cm`BC.Q=Ὶ@bcd8\2cm,R]^_2cm`AXaᔣ᜜3cm`BD.AKL▢⍝M◖82cm,R]^_2cm,BKL%gE.AஹBEhiὅḄlmn᷈/0Ḅ-.p-.3ஹqrstᶭᶭᦔᨬwḄxyA.z?B.{|?C.}|?D.Q=⚠?E.~?

534ஹῚᑁ@ᶭ=⚠?AḄᑺ
xA.=^ᑺ
B.=⚠=^ᑺ
C.%Ὶᑺ
D.=⚠᯿ᑺ
E.=⚠n᷈᯿ᑺ
5ஹᐵLQ=⚠-ᐺ"ḄxA.▲ᙠ8Ḅ1/3,l᝱ஹᜧ-.Xᜫ᩽ឋB.▲ᙠ8Ḅ1/3,l᝱ஹᜧ-.X£¤ᢝ᩽ឋC.8¦ᓄᓰ8Ḅ1/3,8᣸ᑡ«¬X᩽ឋ®ᐰ¯ᜫD.▲ᙠ8Ḅ81/3,l᝱ஹᜧ-.X£¤ᢝ᩽ឋE.▲ᙠ8Ḅ81/3,l᝱ஹᜧ-.Xᜫ᩽ឋ6ஹQ=⚠?R±²ᳮ´ᨬµ¶A.·¸¹?B.º»?C.¼ᜮ¾¹?D.¿?E.¹?7ஹ=⚠bK?µÀLA.¿¾8B.Á¾8C.=⚠ÂᖃD.Ä8E.¿-Á8ÅÆᜐ2)X⚪8ஹ=⚠?ÉÊËᑡ±Ì;A.▢⍝-ÎᑣÐ⊈

54B.ÒÓឋÊ⊈C.ÔÕ"µD.Ö⚣E.ØញÂÚ9ஹᑡ±⚗ÛÜ,=⚠?ᑖÝᨵßàA.áᱏB.%ῚCTᡈMRIC.ῴåæD.~æE.ᐰçèéê10ஹëìឋQ=ᑗ◀#%Ὶᑗ◀ïA.0ÝB.laÝC.1bÝD.HaÝE.HbÝðஹñòóô11ஹ=⚠8ᑁ᪵᷈CINøஹùú⚪12ஹû=⚠?%Ὶ᜜᯿᯿üḄþm᯿\ÿ஺13ஹᑡ⚠ᶭḄஹ஺⚠ᫀஹ⌱⚪1ஹB2ஹB3ஹD4ஹ5ஹB6ஹI"7ஹE8ஹABCDE9ஹABCDE10ஹCD*ஹ+⚪1ஹ,-.L4~512345ᨵῳ89ᾭ;<=>?@ὅ,-,@"᜜-.CDᜮFG▬IJ-.KDὶᔠ,NJ4O5cm5▢⍝FJTUVὅJ-J@"WῚYZ[\ᐰW᯿_WῚ`a᯿2ஹಔcdḄᶭef

551.ឋh⍝ef2.ឋ▢⍝i3.ᐰjefಕᶭZ⍡1-ឋmhi2.ឋῴoi3.WῚpqrsᓄ4.uvᘤxᓄ஺