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1、生医材料专论Curriculum:Textbook:BiomaterialsScience:AnIntroductiontoMaterialsinMedicine(partII,andIII)By:RuddyD.Ratner;AllanHoffman;FrederickSchoenandJackLemonsTime:Wed9:10AM–NoonClassroom:5730Officehours:Tuesday,Thursday10-12AM(Room5751B)Grade:Presentation:20%(fromChap7)
2、;HomeWork:20%(出考題:選擇題(至少3題),解釋名詞(至少2題),答案及出處)Midterm:25%;FinalTest:35%2WeekContent1Openingstatement2-4II.Biology,Biochemistry,andMedicineBackgroundconcepts[2]3.1-3.3;[3]off[4]3.4;[5]3.5-4.1:5,6,8HostReactionstoBiomaterialsandTheirEvaluation[7]4.2-4.3;[6]4.4-4.6;[8]4
3、.7-4.8;9[9]Midterm3Chap4HostreactionstobiomaterialsandtheirevaluationIntroductionInflammation,woundhealing,andtheforeignbodyresponseInnateandadaptiveimmunity:theimmuneresponsetoforeignmaterialsThecomplementsystemSystemictoxicityandhypersensitivityBloodcoagulationand
4、bloodmaterialsinteractionsTumorigenesisandbiomaterialsBiofilm,biomaterialsanddevice-relatedinfection7Chap5BiologicaltestingofbiomaterialsIntroductiontotestingbiomaterialsInvitroassessmentofTissuecompatibilityEvaluationofblood-materialsinteractionsLargeanimalmodelsin
5、cardiacandvascularbiomaterialsresearchandtestingMicroscopyforbiomaterialsscience8Chap6DegradationofmaterialsinthebiologicalenvironmentIntroduction:degradationofmaterialsinthebiologicalenvironmentChemicalandbiologicaldegradationofpolymersDegradativeeffectsofthebiolog
6、icalenvironmentonmetalandceramicsPathologicalcalcificationofbiomaterials9Chap7Applicationofmaterialsinmedicine,biology,andartificialorgansIntroductionNonthrombogenictreatmentsandstrategiesCardiovascularmedicaldevicesImplantablecardiacassistdevicesArtificialredbloodc
7、ellsubstitutesExtracorporealartificialorgans10Chap7Applicationofmaterialsinmedicine,biology,andartificialorgansOrthopedicapplicationsDentalapplicationAdhesivesandsealantsOphthalmologicalapplicationsIntraocularlensimplantsBurndressingandskinsubstitutesSuturesDrugdeli
8、verysystems11Chap7Applicationofmaterialsinmedicine,biology,andartificialorgansBioelectrodesCochlearprosthesesBiomedicalsensorsandbiosensor