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1、lungcancerWhatisLungCancer?BeginswhencellsinthelunggrowoutofcontrolandformatumorEtiologyandpathogenesisCigarettesmokingOtherfactorsincludeairpollutionsNowadaysItisreportedthattuberculosisisassociatedwiththeincidenceoflungcancerClassificationsAccordingtoanatomy:(1)Centrallung(2)peripherallungca
2、ncerAccordingtohistologicclassification:Smallcelllungcancer(SCLC)andNon-smallcelllungcancer(NSCLC).NSCLCincludesSquamouscellcarcinoma,largecellcarcinoma,adenocarcinoma,adenosquamouscarcinoma.Smallcelllungcancer(SCLC)Oat-cellcarcinomaSCLCgrowsveryrapidlyandisveryaggressive.Soonaftertheoriginalc
3、ellbecomescancerous,itquicklymultipliestoformatumor.ThesecellsswiftlyspreadtodistantsitesinthebodySCLCbelongsinagroupoftumorsderivedfromneuroendocrinecellsthatareresponsiblefortheproductionandsecretionofspecificpeptideproduct.theymayrelatedtoparaneoplasticsyndrome.Cellsareovalorvaguelyspindle-
4、shaped,havescantcytoplasmSquamouscellcarcinomathemostfrequentformofthetumor(30-50percentofallcasesbronchialepitheliumandgrowthinsituItisrelatedtocigarettesmokingCavitationcanoccureinthedistaltotheobstructingmassCentrallocationIntercellularbridgesandcellularpleomorphismsquamouscellcarcinomausua
5、llyoccursnearthebronchi,thetumorcancausecough(sometimesacoughthatistingedwithblood),shortnessofbreath,wheezing,andpneumoniaintheareabetweenthetumorandtheedgeofthelungitcausessymptomsearlyinthediseaseadenocarcinomaareasofscarringisassociatedwiththeoccurrenceofadenocarcinoma.Peripheraladenocarci
6、nomasareusuallywell-circumscribed,grey-whitemassesthatrarelycavitate.Itarisesfromthesubmucosalglands,locatedinperipheralairwaysandalveoliFemalelargecellcarcinomalargenuclei,prominentnucleoli,abundantcytoplsmausuallylocatedperipherallycanbequitelargeandnotinfrequentlycavitatetheSymptomsofLungCa
7、ncerFatigue(tiredness)CoughShortnessofbreathChestpainLossofappetiteCoughingupphlegmHemoptysis(coughingupblood)Ifcancerhasspread,symptomsincludebonepain,difficultybreathing,abdominalpain,headache,weakness,andconfusionDuetoprimarylesions:
