脑动静脉畸形--大学课件讲课稿.ppt

《脑动静脉畸形--大学课件讲课稿.ppt》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。

1、脑动静脉畸形--大学课件EmbryologyFirsthalfofthirdweekofgestationepiblasticcellsmigratetoformmesodermmesodermalcellsdifferentiatetoarterialandvenousvesselsonthesurfaceoftheembryonicnervoussystemEmbryologyFirsthalfofthirdweekofgestationepiblasticcellsmigratetoformmesodermmesoderma

2、lcellsdifferentaitetoarterialandvenousvesselsonthesurfaceoftheembryonicnervoussystemSeventhgestationalweekvesselssproutbranches&penetratedevelopingbrainreachthegray-whiteinterface,eitherloopbacktopialsurfaceortraverseentireneuraltube,thusepicerebral&transcerebralcirc'

3、neventuallyconnectarterialandvenoussystemsbyaroundthetwelfthweekPathology&PathophysiologyabsenceofnormalcapillarysystemPathology&PathophysiologyabsenceofnormalcapillarysystemusualfunctiondisplacedPathology&Pathophysiologyabsenceofnormalcapillarysystemusualfunctiondisp

4、lacedasymptomaticatbirthPathology&PathophysiologyabsenceofnormalcapillarysystemusualfunctiondisplacedasymptomaticatbirthvesselschangewithtimemaydevelopaneurysmsparenchymalchangeswithinandaroundthelesionPathology&Pathophysiologyabsenceofnormalcapillarysystemusualfuncti

5、ondisplacedasymptomaticatbirthvesselschangewithtimemaydevelopaneurysmsparenchymalchangeswithinandaroundthelesionsitefrequencyisproportionaltobrainvolumePathology&Pathophysiologyabsenceofnormalcapillarysystemusualfunctiondisplacedasymptomaticatbirthvesselschangewithtim

6、emaydevelopaneurysmsClinicalpresentation95%havesymptomsbyageof70yearsClinicalpresentation95%havesymptomsbyageof70yearspeakpresentationsecondtofourthdecadeClinicalpresentation95%havesymptomsbyageof70yearspeakpresentationsecondtofourthdecadehighoutputfailure,neonate,vei

7、nofGalenhydrocephalus,firstdecadeheadache,hemorrhage,seizures,2nd&3rdClinicalpresentationfactorscontributingtosymptomsvesselwalls,flowandpressuresClinicalpresentationfactorscontributingtosymptomsvesselwalls,flowandpressuresenlargementandencroachmentClinicalpresentatio

8、nfactorscontributingtosymptomsvesselwalls,flowandpressuresenlargementandencroachmentduralsinusesClinicalpresentationfactorsc