AD危险因素及干预因素ppt课件.ppt

《AD危险因素及干预因素ppt课件.ppt》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。

1、AD的危险因素与干预运动锻炼与AD关系目的：whetheranactivityspecificexerciseprogramcouldimproveabilitytoperformbasicmobilityactivitiesinlong-termcareresidentswithAD.方式：Anactivityspecificexerciseprogramwascomparedtoawalkingprogramandtoanattentioncontrol.评估方法：assessedusingthesubscalesoftheAcuteCar

2、eIndexofFunction;functionalmobilitywasmeasuredusingthe6-MinuteWalktest.Theprogramwasdesignedtobeimplemented5timesperweekbyanursingassistantorfamilymemberunderthesupervisionofaphysicaltherapist.thisstudysuggestthatwalkingprogramsmaynotbesufficienttoimprovemobilitylimitationsi

3、nindividualswhoaredependentintransfersandsupportthebenefitofatargeted,simpleexerciseprograminreducingmobilitylimitationsininstitutionalizedpatientswithmoderatetoseverecognitiveimpairment.----ARandomizedControlledTrialofanActivitySpecificExerciseProgramforIndividualsWithAlzhe

4、imerDiseaseinLong-termCareSettings.JGeriatrPhysTher2011;34:50-56.regularleisureexercisemaydecreasetheriskofdevelopingdementiainlate-life---APOEε4allele,cognitivedysfunction,andobstructivesleepapneainchildren.Neurology.2007;69(3):243-9.VascularFactors与AD高血压:Thereisfairlyrobus

5、tevidencelinkingmidlifehypertensiontothedevelopmentofdementiainlaterlife.individualswithraisedsystolicbloodpressure(>160mmHg)atmidlifehadasignificantlyhigherriskofADlaterinlife----MidlifevascularriskfactorsandAlzheimer'sdiseaseinlaterlife:longitudinal,populationbasedstudy.Br

6、itMedJ.2001;322:1447-51.cerebrovascularatherosclerosisandincreasedburdenofsubcorticalwhitematterlesionscommonlyfoundinAD.卒中或TIA增加发生AD：TheriskofdevelopingAD,andnotmerelyvasculardementia,issignificantlyincreasedinindividualswithstrokeortransientischemicattacks---Theroleofcereb

7、ralischemiainAlzheimer’sdisease.NeurobiolAging.2000;21:321-30.CerebralhypoxiaaccruingfromsleepapneahasbeenlinkedtoAD---MidliferespiratoryfunctionandincidenceofAlzheimer'sdisease:A29-yearlongitudinalstudyinwomen.NeurobiolAging.2007;28(3):343-50.营养、饮食与AD“Mediterranean”diet:The

8、diethasrecentlybeenlinkedtoareducedriskoflate-lifecognitivedecline123,124,M