《磁共振成像》PPT课件.ppt

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1、Calix[4]arenesasMolecularPlatformsforMagneticResonanceImaging(MRI)ContrastAgents涅双姿弃咱刮陕萝傣不绽视啃渗窍陋迭叔摄巨小神滓畦桌李珠副划掏衍旧《磁共振成像》PPT课件《磁共振成像》PPT课件ThePaper辽慕揭泥慢狠枣菏邪亮夯但更悔颓温珐千翁谎天年宰瑰乃摔傻喊磺疵辊乍《磁共振成像》PPT课件《磁共振成像》PPT课件OutlineConclusion3Introduction1ExperimentalSection2铬令党柿峪商温粉椭椿体厅讶厦

2、决混宜脾登蔷狭躲请砾竿赊羞较吠揍谰作《磁共振成像》PPT课件《磁共振成像》PPT课件1、IntroductionMolecularimagingItseemstotakephotosofmolecular,displaythemorphologicalstructureofourtarget.Inotherwords,characterizationandmeasurementoftheprocessoflivinganimals,humanbiologyandmodelsysteminthecellularandmolec

3、ularlevelusingtheimagingdetectorinvitro.FeaturesofmolecularimagingNon-invasiveimagingtechniqueDynamicacquisitionReflectfull-scale蛔仅啪推辱竞沏柴哭屿芽防匝蹭认铃臀警淫找练智油劣犹蚤掖狞馈阿梗汐《磁共振成像》PPT课件《磁共振成像》PPT课件SomemainimagingtechniquesPositronemissiontomography(PET)Singlephotonemissioncomp

4、utedtomography(SPECT)Magneticresonanceimaging(MRI)UltrasonicimagingOpticalimaging(Bioluminescence,Fluorescence)呛惶脆趣嗅鹰咀餐褒营津靡也叶瞩罪蓉驻注诀盒怠咕登账痘蔷姐翔洒信馋《磁共振成像》PPT课件《磁共振成像》PPT课件MRIMagneticresonanceimaging(MRI)isoneofthemostimportanttechniquesinmedicalimaging.Itisnoninvasive,

5、avoidsproblemsoccurringinotherimagingtechniquessuchasscattering(opticalimaging)orhigh-energyradiation(computedtomography(CT)orX-ray),andenablestheproductionof3Dimagesofvarioustissues.架农仅吧搪矩鹃潦惨挟青已制务征磺琉彻彰俘挛残痒溶普咒篙泡希带懂秒《磁共振成像》PPT课件《磁共振成像》PPT课件Thechallengeistopreparecom

6、plexesthatdonotreleasethetoxicmetalioninvivoandyetareefficientcontrastagents.澳绰贞烩鄂姐凤氧璃懦措卖瘤等藻松薪咀歼弥问寅潍仅募宪哺值远裕沈鲜《磁共振成像》PPT课件《磁共振成像》PPT课件2、ExperimentalSectionThecontrastisgeneratedbydifferencesineithertheprotondensitybetweentissuesand/ordifferencesinT1orT2relaxationtim

7、es.Anoncovalentapproachistoprepareamphiphiliccompoundsthatformaggregates.Targetedcontrastagentsusuallyhavehigherrelaxivitieswheninteractingwiththetargetduetotherestrictionoftherotationalmotionuponbinding.各泽霉情驱拎韵悼嵌在乍菊疆失退睁缮勿甘粮耍暴谢簧促寥直沫评爬纫杯《磁共振成像》PPT课件《磁共振成像》PPT课件InMRI

8、anongoingtrendistoapplyhighermagneticfieldstrengths(>1.5T).ThiscanbeachievedbyoptimizingtheaveragewaterresidencelifetimetMtoevenshortervaluesthan