生物安全培训课件(实验篇).ppt

生物安全培训课件(实验篇).ppt

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时间:2020-07-26

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1、BiosafetyPracticesandProceduresPresentedby:YangY19Jun2012BiosafetyConcept:Biologicalsafetyistopreventoccupationalacquiredinfectionsaswellasthereleaseofpathogensintotheenvironment.Biosafetyisthepreventionoflarge-scalelossofbiologicalintegrity,focusingbo

2、thonecologyandhumanhealth.Biological&BiosecurityBiosafetyisrelatedtoseveralfieldsInecologyInagricultureInmedicineInchemistryInexobiologyPrecautionaryprincipleBiosafetyrequireapplicationoftheprecautionaryprincipleinordertopreventtheaccidentalreleaseofpo

3、tentiallydestructivebiologicalmaterial.BiosafetylevelAbiosafetylevelisthelevelofthebiocontainmentprecautionsrequiredtoisolatedangerousbiologicalagentsinanenclosedfacility.Biocontainmentcanbeclassifiedbytherelativedangertothesurroundingenvironmentasbiol

4、ogicalsafetylevels(BSL).Thelevelsofcontainmentrangefromthelowestbiosafetylevel1(BSL-1)tothehighestatlevel4(BSL-4).Biosafetylevel1Thislevelissuitableforworkinvolvingwell-characterizedagentsnotknowntoconsistentlycausediseaseinhealthyadulthumans,andofmini

5、malpotentialhazardtolaboratorypersonnelandtheenvironment.Suchascaninehepatitis,non-pathogenicEscherichiacoli,aswellassomecellculturesandnon-infectiousbacteria.Biosafetylevel2ThislevelissimilartoBiosafetyLevel1andissuitableforworkinvolvingagentsofmodera

6、tepotentialhazardtopersonnelandtheenvironment.Itincludesvariousbacteriaandvirusesthatcauseonlymilddiseasetohumans,oraredifficulttocontractviaaerosolinalabsetting.SuchasC.difficile,mostChlamydiae,hepatitisA,B,andC,influenzaA,Lymedisease,Salmonella,mumps

7、,measles,HIV,scrapie,MRSA,andVRSA.Biosafetylevel3Thislevelisapplicabletoclinical,diagnostic,teaching,research,orproductionfacilitiesinwhichworkisdonewithindigenousorexoticagentswhichmaycauseseriousorpotentiallylethaldiseaseafterinhalation.Itincludesvar

8、iousbacteria,parasitesandvirusesthatcancauseseveretofataldiseaseinhumansbutforwhichtreatmentsexist.SuchasMycobacteriumtuberculosis,Bacillusanthracis,SARScoronavirus,Salmonellatyphi,andyellowfevervirus.Biosafetylevel4Thislevelisrequiredf

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