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1、ClinicalPharmacogeneticsImplementationConsortium(CPIC)GuidelinesforCYP3A5GenotypeandTacrolimusDosing1,2342,52,6KellyA.Birdwell,BrianDecker,JuliaM.Barbarino,JoshF.Peterson,C.MichaelStein,778910WolfgangSadee,DanxinWang,AlexanderA.Vinks,YijingHe,JesseJ.Swen,J.
2、Steven111213414Leeder,RHNvanSchaik,KennethE.Thummel,TeriE.Klein,KellyE.Caudle,Iain15A.M.MacPhee1DivisionofNephrologyDepartmentofMedicine,VanderbiltUniversity,Nashville,TN2DepartmentofMedicine,VanderbiltUniversity,Nashville,TN3DivisionofNephrologyandDivision
3、ofClinicalPharmacology,IndianaUniversitySchoolofMedicine,Indianapolis,IN,USA4DepartmentofGenetics,StanfordUniversity,Stanford,CA5DepartmentofBiomedicalInformatics,VanderbiltUniversity,Nashville,TN,USA6DepartmentofPharmacology,VanderbiltUniversity,Nashville,
4、Tennessee,USA7CenterforPharmacogenomics,SchoolofMedicine,TheOhioStateUniversity,Columbus,OH,USA8DivisionofClinicalPharmacology,CincinnatiChildren’sHospitalMedicalCenter,Cincinnati,Ohio,USA;DepartmentofPediatrics,CollegeofMedicine,UniversityofCincinnati,Cinc
5、innati,Ohio,USA9InstituteofClinicalPharmacology,CentralSouthUniversity,Changsha,Hunan,P.R.China10DepartmentofClinicalPharmacyandToxicology,LeidenUniversityMedicalCenter,Leiden,TheNetherlands111DivisionofClinicalPharmacologyandTherapeuticInnovation,Departmen
6、tofPediatricsChildren'sMercyHospitalsandClinics,KansasCity,MO12DepartmentofClinicalChemistry,ErasmusMCRotterdam,TheNetherlands13DepartmentsofPharmaceutics,UniversityofWashington,Seattle,WA14DepartmentofPharmaceuticalSciences,St.JudeChildren’sResearchHospita
7、l,Memphis,TN,USA15InstituteofMedicalandBiomedicalEducation:RenalMedicine,St.George’s,UniversityofLondon,London,UKCorrespondingauthor:KellyBirdwell,MD,MSCIAssistantProfessorofMedicineVanderbiltUniversityMedicalCenterDivisionofNephrologyandHypertensionS-3223M
8、CNNashville,TN37232-2372Phone:615.322.6976Email:kelly.birdwell@vanderbilt.eduWordcounts:Abstract:(75limit):752Text:(3,000limit):2516References:(40limit):39Figures/tables:2tablesKeywords:Upto10Keywords: