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1、putclub.com_20120814SSSFive-hundredyearsago,a15-year-oldIncangirlwassacrificed,alongwithtwootherchildren.Hermummyhasnowrevealedthatshehadanactivelunginfectionatherdeath.Becauseatechniquecalledshotgunproteomicshasbeenusedtodeterminewhethersomeonewasactuallysufferingfromadiseaserath
2、erthanjustcarryingit.ThereportappearsinthejournalPLoSONE.[AngeliqueCorthalsetaL,DetectingtheImmuneSystemResponseofa500-Year-OldIncaMummy]PreviousresearchintoancientdiseaseshasusedDNAanalysistodeterminethepresenceofpathogens.ButwithDNA,there'snowaytotelllatentinfectionsfromthefull-
3、blown,misery-inducingones.Researchersanalyzedproteinsamplesfromthemummiesoftwooftheslainchildren.ThegirTsproteinsindicatedanimmuneresponsetobacteria,perhapsapathogenrelatedtotuberculosis.Otherevidence,suchasmucusunderhernoseandlungabnormalities,strengthenedthediagnosis.Theseven-ye
4、ar-oldboy,ontheotherhand,showednosignsofinfection.Thisisthefirsttimethetechniquehasbeenused.It,sasmallsample,butfurtherdevelopmentofshotgunproteomicshasthepotentialtoimproveourunderstandingofancientdisease,aswellasassistingintomorrow'sforensicinvestigations.putclub.com_20120416SSS
5、ThisisScientificAmericans60secondScience,IamCythiaGraberSpringisintheair.Andsoarethosedanginsects,hungryforabloodmeal.Thevictimcanwindupwithabunchofbites,redanditchy.Sowhatdrugscanquenchthatitch?Maybenone,accordingtoastudyintheDrugandTherapeuticsBulletin.Researchersreviewedthelite
6、ratureonavarietyoftreatments.Topicalantihistamines?Generallynotrecommended.TheyYeonlymarginallyeffectiveandshouldn'tbeusedforlongerthanthreedays.Oralanalgesicslikeibuprofenaresometimesrecommended,butthescientistssaythere'snoevidencesupportingthat.Topicalanestheticssuchaslidocainea
7、reonlymarginallyeffectiveandcansensitizetheskin—neaningtheitchingcouldultimatelygetworse.Andcommontopicalsteroidslikehydrocortisone?TheproblemhereisthattheyYenotsupposedtobeusedonbrokenskin.Andifyou'vebeenscratching,thatskinmayalreadybebroken.Theauthorsrecommendasimpleapproach:cle
8、anthearea,anduseacoldpacktotampdo
