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时间:2020-05-14
《广州地区引起食物过敏性疾病的变应原谱分析.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、国际检验医学杂志2015年7月第36卷第13期IntJLabMed,July2015,Vo1.36,No.13·1813··论著·广州地区引起食物过敏性疾病的变应原谱分析陈韵,黄惠敏,郑佩燕。,孙宝清(1.广州市越秀区妇幼保健院检验科,广东广州510055;2.广州呼吸疾病研究所,广东广州510120)摘要:目的分析食物过敏患者血清中13种相同食物变应原特异性IgG(slgG)和特异性IgE(slgE)在不同年龄和性别间的分布特征,探讨两者在食物过敏性疾病中的关系。方法以2009~2012年门诊314例患者为研究对象,并根据年龄分为未成年组(163例)与成年组(151例);
2、通过酶联免疫吸附试验检测患者血清中13种食物变应原slgG,同时通过免疫捕获法检测患者血清中的sIgE结果8O.25的患者slgG呈阳性反应,阳性率无明显性别差异,但未成年组(94.48)高于成年组(64.90Y0),差异有统计学意义(P<0.05);34.39的患者slgE呈阳性反应,男性阳性率(40.68)高于女性(26.28),未成年组(55.2,0/:高于成年组(11.92),差异均有统计学意义(P3、;食物过敏;特异性IgG抗体;特异性IgE抗体;分布特征DOI:10.3969/j.issn.1673—4130.2O15.13.005文献标识码:A文章编号:1673—4130(2015)13-1813。3AnalysisoffoodallergenspectrumsinfoodanaphylaxisinGuangzhouChenYun,WangHuimin,ZhengPeiyan。,SunBaoqing。(1.DepartmentofClinicalLaboratory,YuexiuDistrictWomenandChildrensHospital,Guangzhou,4、Guangdong510055,China;2.GuangzhouInstituteofRespiratoryDisease,Guangzhou,Guangdong510120,China)Abstract;ObjeetiveToanalysedistributionofageandgendercharacteristicsofspecificIgG(sIgG)antibodiesandspecificIgE(sIgE)antibodiesof13typesoffoodallergensinpatientswithfoodanaphylaxis,andtoexploreth5、erelationshipbetweensIgGandslgEinfoodanaphylaxis.Methods314casesofpatientsfrom2009to2012wereselectedassubjects,anddividedintounderagegroup(163cases)andadultgroup(t51cases).SerumsIgGof13typesoffoodallergensweredetectedbyusingenzymelinkedimmu—nosorbentassay,serumslgEofthesefoodallergenswered6、etectedbyusingimmunecapture.Results80.25ofthepatientswereslgG-positive,andnoobviousgenderdifferenceswerefound;whilethepositiveratesofslgGintheunderagegroup(94.48)werehigherthanthatintheadultgroup(64:90),therewerestatisticallysignificantdifferences(P<0.05).34.39ofthepatientswereslgE—positiv7、e.ThepositiveratesQfsIgEinmalepatients(4O.68)werehigherthanthatinfemalepa'tients(26.28),andthatintheunderagegroup(55.21)werealsohigherthanthatintheadultsgroup(11.92),therewerestatisticallysignificantdifferences(P
3、;食物过敏;特异性IgG抗体;特异性IgE抗体;分布特征DOI:10.3969/j.issn.1673—4130.2O15.13.005文献标识码:A文章编号:1673—4130(2015)13-1813。3AnalysisoffoodallergenspectrumsinfoodanaphylaxisinGuangzhouChenYun,WangHuimin,ZhengPeiyan。,SunBaoqing。(1.DepartmentofClinicalLaboratory,YuexiuDistrictWomenandChildrensHospital,Guangzhou,
4、Guangdong510055,China;2.GuangzhouInstituteofRespiratoryDisease,Guangzhou,Guangdong510120,China)Abstract;ObjeetiveToanalysedistributionofageandgendercharacteristicsofspecificIgG(sIgG)antibodiesandspecificIgE(sIgE)antibodiesof13typesoffoodallergensinpatientswithfoodanaphylaxis,andtoexploreth
5、erelationshipbetweensIgGandslgEinfoodanaphylaxis.Methods314casesofpatientsfrom2009to2012wereselectedassubjects,anddividedintounderagegroup(163cases)andadultgroup(t51cases).SerumsIgGof13typesoffoodallergensweredetectedbyusingenzymelinkedimmu—nosorbentassay,serumslgEofthesefoodallergenswered
6、etectedbyusingimmunecapture.Results80.25ofthepatientswereslgG-positive,andnoobviousgenderdifferenceswerefound;whilethepositiveratesofslgGintheunderagegroup(94.48)werehigherthanthatintheadultgroup(64:90),therewerestatisticallysignificantdifferences(P<0.05).34.39ofthepatientswereslgE—positiv
7、e.ThepositiveratesQfsIgEinmalepatients(4O.68)werehigherthanthatinfemalepa'tients(26.28),andthatintheunderagegroup(55.21)werealsohigherthanthatintheadultsgroup(11.92),therewerestatisticallysignificantdifferences(P
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