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1、上海交通大学生物化学试卷(2003年度)校名___________系名___________专业___________姓名___________学号___________日期___________2003TESTPAPER(1)(闭卷部分)(ShanghaiJiaoTongUniversity,1sttermofUniv.year2003)Subject:BiochemistryName_____________Score_____________Class_____________一.Explaintheterms:(2.5x10
2、=25)1.hyperuricemia2.LDLreceptor3.pyruvatedehydrogenasecomplex4.glucokinase(inliver)5.malate-aspartateshuttle6.PRPP7.substratecycle8.“macroCoA”9.ureacycle10.UDP-glucose2003TESTPAPER(2)(开卷)(ShanghaiJiaoTongUniversity,1sttermofUniv.year2003)Subject:BiochemistryName______
3、_______Score_____________Class_____________二.Fillingtheblanks:(2.5x12=30)1.Manyimportantcoenzymes,suchas____,____and____,arethederivativesofADP;dNDParesynthesizedfrom____anddTMPisformedby________ofdUMP;allthesefactsreflectsthat_____camebefore______inevolution.2.TPPisth
4、ederivativeofvitamin____,itservesastheprostheticgroupofthefollowingenzymes:_____________,_____________and_____________.3.Thereisalargedifferencebetweentheyieldfromthecompleteoxidationoftriacylglycerolsandofcarbohydrates(andprotein),thereasonis__________________________
5、_________________________.4.Thethreepairsofenzymesthatcatalyzethethreeresemblestepsinβ-oxidationofFAandcitricacidcycleare_____________and_____________,_____________and_____________,_____________and_____________.5.TheonlyreactionsinmammalsthatrequirecoenzymeB12are______
6、____________________and_______________________catalyzedby_____________and_____________,respectively.6.OAAhasseveralpossiblefates:_____________,_____________,_____________and_____________.7.Inthesynthesisofphosphoglycerides磷酸甘油酯andofglycogen,theactivatedintermediatesare
7、_____________and_____________,bothofthemareformedfroma_____________substrateanda_____________,andthenreactwitha_____________group.8.Thecommittedstepincholesterolbiosynthesisisthesynthesisof_____________from_____________whichiscatalyzedby_____________.9.Thecarrierofthea
8、ctivatedone-carbonunitsis_____________whichconsistsofthreegroups:_____________,_____________and_____________.Besides,