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时间:2020-05-09
《比索洛尔联合甲巯咪唑治疗甲状腺功能亢进症的临床疗效.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、110北方药学2015年第l2卷第7期比索洛尔联合甲巯咪唑治疗甲状腺功能亢进症的临床疗效杜凌超(东莞市第八人民医院(东莞市儿童医院)内科二区东莞523320)摘要:目的:探讨比索洛尔联合甲巯咪唑治疗甲状腺功能亢进症的临床治疗效果,并分析其应用价值。方法:选取2012年10月~2013年l1月我院收治的104例甲状腺功能亢进症患者,随机分为两组,每组52例。对照组采用甲巯咪唑治疗,实验组采用比索洛尔联合甲巯咪唑治治疗。比较两组的临床治疗效果以及患者的不良反应情况。结果:实验组总有效率为98.07%,显著高于
2、对照组的61.54%(P<0.05),差异具有统计学意义;实验组游离三碘甲状腺原氨酸含量、高敏促甲状腺素、游离甲状腺素、总三碘甲状腺原氨酸的改善情况,均显著优于对照组(Pl<0.05),差异具有统计学意义;实验组体质量及心率改善程度,明显优于对照组(Pl3、R581.1文献标识码:B文章编号:1672—8351(2015)07—011O一03TheclinicaleficacyofbisoproiolcombinedwithmethimazoletreatmentofhyperthyroidismDuLingchao(Departmentofinternalmedicine,twodistrict,TheEighthPeoplesHospitalofDongguan(ChildrenSHospitalofDongguan),Guangdong,523320,4、China)Abstract:Objective:Toresearchtheclinicalefectofbisoprololcombinedwithmethimazoletreatmentofhyperthyroidism,andanalyzesitsapplicationvalue.Methods:104casesofpatientswithhyperthyroidisminourhospitalfromOctober2012toNovember2013,wererandomlydividedinto5、twogroups,52casesofeachgroup.thecontrolgroupwasusemethimazoletreatment,theexperimentalgroupwereusebisoprololcombinedwithmethimazoletreatment.comparedClinicaltreatmenteffectoftwogroups.Results:Theexperimentalgroupoftotalefectiveratewas98.07%,significantlyh6、igherthanthecontrolgroup61.54%(P<0.05),thedifferencewasstatisticallysignificant;theexperimentalgroupoffreethreeiodothyroninecontent,GaoMinthyrotropin,freethyroxine,totalthreeiodothyronineimprovement,weresignificantlybetterthanthecontrolgroup(P<0.05),thedi7、fferencewasstatisticallysignificant;theexperimentalgroupbodyweightandheartrateimprovement,weresignificantlybetterthanthecontrolgroup(P<0.05),thediferencewasstatisticallysignificant.Conclusion:bisoprolotcombinedwithmethimazoletreatmentofhyperthyroidismwith8、significantcurativeeffect,issafeandreliable,worthyofclinicalpromotionandapplication.Keywords:BisoprololMethimazoleHyperthyroidismClinicalefect甲状腺功能亢进症(hyperthyroidism,简称甲亢),是指甲状有限公司生产,国药准字号:H31021440)进行治疗,第一个月每腺本身的病
3、R581.1文献标识码:B文章编号:1672—8351(2015)07—011O一03TheclinicaleficacyofbisoproiolcombinedwithmethimazoletreatmentofhyperthyroidismDuLingchao(Departmentofinternalmedicine,twodistrict,TheEighthPeoplesHospitalofDongguan(ChildrenSHospitalofDongguan),Guangdong,523320,
4、China)Abstract:Objective:Toresearchtheclinicalefectofbisoprololcombinedwithmethimazoletreatmentofhyperthyroidism,andanalyzesitsapplicationvalue.Methods:104casesofpatientswithhyperthyroidisminourhospitalfromOctober2012toNovember2013,wererandomlydividedinto
5、twogroups,52casesofeachgroup.thecontrolgroupwasusemethimazoletreatment,theexperimentalgroupwereusebisoprololcombinedwithmethimazoletreatment.comparedClinicaltreatmenteffectoftwogroups.Results:Theexperimentalgroupoftotalefectiveratewas98.07%,significantlyh
6、igherthanthecontrolgroup61.54%(P<0.05),thedifferencewasstatisticallysignificant;theexperimentalgroupoffreethreeiodothyroninecontent,GaoMinthyrotropin,freethyroxine,totalthreeiodothyronineimprovement,weresignificantlybetterthanthecontrolgroup(P<0.05),thedi
7、fferencewasstatisticallysignificant;theexperimentalgroupbodyweightandheartrateimprovement,weresignificantlybetterthanthecontrolgroup(P<0.05),thediferencewasstatisticallysignificant.Conclusion:bisoprolotcombinedwithmethimazoletreatmentofhyperthyroidismwith
8、significantcurativeeffect,issafeandreliable,worthyofclinicalpromotionandapplication.Keywords:BisoprololMethimazoleHyperthyroidismClinicalefect甲状腺功能亢进症(hyperthyroidism,简称甲亢),是指甲状有限公司生产,国药准字号:H31021440)进行治疗,第一个月每腺本身的病
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