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《小儿轮状病毒性肠炎肝功能和心肌酶谱检测的临床意义-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、80·实用临床医学2014年第15卷第4期PracticalClinicalMedicine,2014,Vol15,No4·小儿轮状病毒性肠炎肝功能和心肌酶谱检测的临床意义高运金.陈圣玺(惠州市惠阳区人民医院儿科,广东惠州516211)摘要:目的探讨轮状病毒对d,JL肝脏和心肌造成的不良影响。方法使用全自动生化分析仪、采用酶联免疫吸附法检测60例轮状病毒性肠炎患儿(观察组)和60例大便细菌培养与轮状病毒检测结果均为阴性的腹泻患儿(对照组)血清肝功能【谷丙转氨酶(ALT)、谷草转氨酶(AsT)]和心肌酶谱【肌酸激酶同工酶(CK—MB)、肌酸激酶(CK)
2、和乳酸脱氢酶(LDH)]的水平,并观察2组肝脏、心肌损伤发生率的情况。结果观察组血清LDH(262.39~92.47)U·L一、CK—MB(49.99~33.87)U·L~、CK(197.52~82.36)U·L~、AST(38.20~23.98)U·L和ALT(40.24~24.89)U·L水平,均明显高于对照组的(193.33~76.58)U·L一、(22.53~20.67)U·L~、(139.99~70.87)U·L一、(25.31~16.59)U·L和(24.33~18.64)U·L-(均P3、7%、51.7%。均明显高于对照组的16.7%、18-3%(均/'<0.05)。结论小儿轮状病毒性肠炎常合并肝脏、心肌损害.应尽早对轮状病毒性肠炎患儿进行肝功能及心肌酶的检测,以便临床及早对轮状病毒性肠炎患儿进行干预治疗。关键词:轮状病毒性肠炎;轮状病毒感染;心肌酶谱;肝功能;心肌损伤;肝损伤;d,JL中图分类号:R725.7;R446.1文献标志码:A文章编号:1009—8194(2014)04—0080—03ClinicalSignificanceofDetectionofLiverFunctionandMyocardialEnzymeSpect4、ruminChildrenwithRotavirusEnteritisGAOYun-jin,CHENSheng-xi(DepartmentofPediatrics,HuiyangDistrictPeople’SHospitalofHuizhou,Huizhou516211,China)ABSTRACT:ObjectiveTostudytheadverseeffectsofrotavimsontheliverandmyocardiuminchildren.MethodsThelevelsofalanineaminotransferase(ALT),as5、partateaminotransferase(AST),cre—atinekinaseisoenzyme(CK-MB),ereatinekinase(CK)andlaetatedehydrogenase(LDH)weremeasuredbvEUSAusingautomaticbiochemicalanalyzerin60childrenwithrotavirusenteritis(observationgroup)and60childrenwithnegativebacterialstoolcultureandrotavirusdetectionr6、esults(controlgroup).Moreover,theincidencesofhepaticandmyocardialinjurywereobservedinbothgroups.ResultsThelevelsofserumLDH,CK—MB,CK,ASTandALTinobservationgroup[(262.39~92.47)U·L~,(49.99~33.87)U·L~,(197.52±82.36)U-L~,(38.20~23.98)U·L~and(40.24+24.89)U·L~,respectively】weresignifi7、cantlyhigherthanthoseincontrolgroup[(193.33~76.58)u·L-l,(22.53+20.67)U·L~,(139.99~70.87)U·L~,(25.31~16.59)U·L—and(24.33+18.64)U·L-l,respectively1(P8、nthoseincontrolgroup(16.7%and18.3%,respectively)(P<0.0
3、7%、51.7%。均明显高于对照组的16.7%、18-3%(均/'<0.05)。结论小儿轮状病毒性肠炎常合并肝脏、心肌损害.应尽早对轮状病毒性肠炎患儿进行肝功能及心肌酶的检测,以便临床及早对轮状病毒性肠炎患儿进行干预治疗。关键词:轮状病毒性肠炎;轮状病毒感染;心肌酶谱;肝功能;心肌损伤;肝损伤;d,JL中图分类号:R725.7;R446.1文献标志码:A文章编号:1009—8194(2014)04—0080—03ClinicalSignificanceofDetectionofLiverFunctionandMyocardialEnzymeSpect
4、ruminChildrenwithRotavirusEnteritisGAOYun-jin,CHENSheng-xi(DepartmentofPediatrics,HuiyangDistrictPeople’SHospitalofHuizhou,Huizhou516211,China)ABSTRACT:ObjectiveTostudytheadverseeffectsofrotavimsontheliverandmyocardiuminchildren.MethodsThelevelsofalanineaminotransferase(ALT),as
5、partateaminotransferase(AST),cre—atinekinaseisoenzyme(CK-MB),ereatinekinase(CK)andlaetatedehydrogenase(LDH)weremeasuredbvEUSAusingautomaticbiochemicalanalyzerin60childrenwithrotavirusenteritis(observationgroup)and60childrenwithnegativebacterialstoolcultureandrotavirusdetectionr
6、esults(controlgroup).Moreover,theincidencesofhepaticandmyocardialinjurywereobservedinbothgroups.ResultsThelevelsofserumLDH,CK—MB,CK,ASTandALTinobservationgroup[(262.39~92.47)U·L~,(49.99~33.87)U·L~,(197.52±82.36)U-L~,(38.20~23.98)U·L~and(40.24+24.89)U·L~,respectively】weresignifi
7、cantlyhigherthanthoseincontrolgroup[(193.33~76.58)u·L-l,(22.53+20.67)U·L~,(139.99~70.87)U·L~,(25.31~16.59)U·L—and(24.33+18.64)U·L-l,respectively1(P8、nthoseincontrolgroup(16.7%and18.3%,respectively)(P<0.0
8、nthoseincontrolgroup(16.7%and18.3%,respectively)(P<0.0
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