人工角膜及其相关材料

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1、万方数据中国组织工程研究与临床康复多事胆卷第JD勇铲2008一03—04出版JournalofClinicalRehabilitativeTissueEngineeringResearchMarcht2008V01．12，No．10人工角膜及其相关材料：l=★严拓1，敖宁建1，覃百花1，邓华2ArtificialcorneaandrelatedmaterialsYanTu01，AoNing-jianl，TanBai-hual，DengHua2AbstractBACKGRoUND：Asforthep

2、atientwhofailshomologouscornealimplantation．theonlyalternativeforrestoringvisionisartificialcornea．Aldioughthestudyofartificialcomeahasbeenstraddlingfortwocenturies，however，thesurgerycanbeonlycarriedoutinafewspecialcentersduetothelimitingfactors．Inrec

3、entyears，astherapiddevelopmentofrelevantdisciplines，artificialcorneahasenteredarapiddevelopingperiod．oBJECTIVE：Toillustratethematedalchoice，structure。materialmodificationandclinicaltrialsoftheartificialcornea,comparethecharacteristicsofdifferentstruct

4、uresartificialcomea，pointoutthecurrentdisadvantagesofeachkindofcornea，andproposeareasonableprospecttotheidealartificialcornea．RETRIEVALSTRATEGY：Acomputer-basedsearchofChinaFull-textJournalDatabase．Springer,EI．BlackwellDatabasewasundertakentoidentifyth

5、earticlespublishedfromJanuary1993toDecember2007．withthekeywordsof”artificialcornea,penetratingkeratoplasty”inbothChineseandEnglish．Inclusivecriteria：articlesrelatedtothematerial，designandclinicalstudy0fartificialcornea．Exclusivecriteria：outdatedandrep

6、etitionresearches．LITERATUREEVALUATIoN：Atotalof86articleswerecollected．including68mettheinclusivecriteria,inwhichtherewere12reviewarticles．37basicresearchesand19elinicalresearches．Finally30atticleswereselectedforreviews．DATASYNTHESIS：Thematerialsofart

7、ificialcomeaincludeopticalmaterials(hydrogel，polymethylmethacrylate，silicagel，glass)andscaffoldmaterials(fluorine—carbonpolymer,hydroxyapatiteceramic，biomaterial)．Materialsmodificationconsistsofchemicalmodification，surfacetreatment，andsurfaceplasmatre

8、atment。etc'．11地SUCCESSfuldesignmodelsofartificialcolTleaareAlphaCorandOsteo-Odonto，whichhavebeenapprovedbytheAmericanFoodandDrugAdministrationandhaveappliedontheclinicalpractice．CONCLUSIoN：Thefurtherstudyshouldbefocusedonelevatingtheattachment