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时间:2020-04-12
《《肥胖模型大鼠锌营养状态指标的检测及意义》.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、中国实验诊断学2015年7月第19卷箜!-——1049-—·——actininclusionsinducedinneuronsbystressoramyloidbeta:abioa.22549.feedforwardmechanismforAlzheimerSdisease[J].Maloney[17]RahmanT,DaviesDS,TannenbergRK,eta1.CofilinRodsandMT。MinamideLS,KinleyAW,eta1.JNeurosci,2005,25(49):AggregatesConcurwithTauPatholog
2、yandtheDevelopmentof11313.Erratumin:JNeurosci,2006,26(1):354.AtzheimefsDisease[J].JAlzheimersDis,2014,11:235.[15-1LiseNicoleMunsie,CarlyR.DesmondandRayTruant.Cofilin[18]田磊,廖明芳,李冀洲,等.细胞骨架蛋白中ADF/cofilin蛋白nuclear—cytoplasmicshuttlingaffectscofilin—actinrodformation家系的作用:如何与肌动蛋白结合及发挥解聚
3、作用EJS?中国组duringstress[J].JournalofCellScience,2012,125(17):3977.织工程研究与临床康复,2009,13(5o):9941.[-163MunsieLN1,TruantR.Theroleofthecofilin—actinrodstress(收稿日期:2015—03—15)responseinneur0degeneratiVediseasesuncoverspotentialnewdrugtargets[J].Bioarchitecture,2012,2(6):204.doi:10.4161/文章编号
4、:1007—4287(2015)07—1049—03肥胖模型大鼠锌营养状态指标的检测及意义陈巾宇,杨野仝,张桂英,杨青,刘雅娟(吉林大学公共卫生学院营养与食品卫生学,吉林长春130021)摘要:目的探讨肥胖大鼠体内锌代谢指标的变化情况,为调整膳食结构,防治肥胖提供理论依据。方法将2O只雄性Wistar大鼠随机分为对照组和肥胖组,每组1O只,分别喂养普通饲料和高脂饲料,8周后眼球取血处死。试剂盒测血清锌含量、碱性磷酸酶活性及血管紧张素转化酶活性。结果与对照组大鼠比较,肥胖组大鼠血清铁含量、碱性磷酸酶活性及血管紧张素转化酶活性均有所升高(P5、会导致锌含量增高,引起锌代谢指标的改变。关键词:肥胖;锌代谢;碱性磷酸酶;血管紧张素转化酶中图分类号:R151文献标识码:ADetectionandsignificanceofObesityratswithzincnutritionalstatnsindicatorsCHENJin—yu,yANGYe—tong。ZHANGGui—ying,eta1.(DepartmentofNutritionandFood,SchoolofPublicHealth,JilinUniversity,Changchun130021,China)Abstract:Objeetiv6、eToinvestigatetheinfluenceofobesityonzincmetabolism.Astheadjustmentofdietarystruc—ture,providesthetheorybasisforthepreventionandtreatmentofobesity.Methods2OmaleWistarrats,wererandom—lydividedintocontrolgroupandobesitygroup,10ratsineachgroup.ordinarydietandhighfatdiet,respectively,T7、hebloodwereobtainedfromeyeballafter8weeks,thenkilltherats.Theserumzinccontent,alkalinephosphataseactivityandangiotensinconversionenzymeactivityweredetected.ResultsComparedwithcontrolgrouprats.Theserumironcontent,alkalinephosphataseactivityandangiotensinconversionenzymeactivityinobe8、sitygroupweresignificantly
5、会导致锌含量增高,引起锌代谢指标的改变。关键词:肥胖;锌代谢;碱性磷酸酶;血管紧张素转化酶中图分类号:R151文献标识码:ADetectionandsignificanceofObesityratswithzincnutritionalstatnsindicatorsCHENJin—yu,yANGYe—tong。ZHANGGui—ying,eta1.(DepartmentofNutritionandFood,SchoolofPublicHealth,JilinUniversity,Changchun130021,China)Abstract:Objeetiv
6、eToinvestigatetheinfluenceofobesityonzincmetabolism.Astheadjustmentofdietarystruc—ture,providesthetheorybasisforthepreventionandtreatmentofobesity.Methods2OmaleWistarrats,wererandom—lydividedintocontrolgroupandobesitygroup,10ratsineachgroup.ordinarydietandhighfatdiet,respectively,T
7、hebloodwereobtainedfromeyeballafter8weeks,thenkilltherats.Theserumzinccontent,alkalinephosphataseactivityandangiotensinconversionenzymeactivityweredetected.ResultsComparedwithcontrolgrouprats.Theserumironcontent,alkalinephosphataseactivityandangiotensinconversionenzymeactivityinobe
8、sitygroupweresignificantly
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