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ID:51659549
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时间:2020-03-14
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1、INTRODUCTIONOFCOMMUNICABLEDISEASESI.TERMS1)OvertinfectionItindicatesthatafterthemicroorganismentersthehost,itnotonlyinducestheimmuneresponsesofthehostbutalsoproduceshisomorphologicaldamageandpathologicalchangesthroughtheroleofthemicroorganismortheallergicreactionofthehost.Inmostinf
2、ectiousdiseasesuchasmeaslesmostinfectedhostmanifestedasovertinfection.Afterovertinfectionendsthemicroorganismcanbeeliminatedandthehostsacquittedconsolidatedimmunity.Insomeinfectiousdiseases(suchasbacillarydysentery)theimmunityistemporary.Asmallamountofovertlyinfectedhostschangetoca
3、rrierstate.Itiscalled“convalescentcarrier”.2)IncubationperiodThisperiodisfrompathogensinvadingintohumanbodytoclinicalsymptomsappearing.Theincubationperiodofallinfectiousdiseaseshasalimitofthetime(theshortestandlongest)andanormaldistribution.Itisanimportantevidenceofobserving,detect
4、ingthecontactinquarantinework.Itisusuallyequaltothewholeperiodincludingthepathogenreproduction,transference,location,tissuedamageandfunctionchangesbeforetheclinicalsymptomstooccur.Theperiodlengthisnegativerelationwiththeinvadingquantityofthepathogens.Ifthepathophysiologicchangesare
5、causedbytoxins,theincubationperiodrelateswiththetimeofthetoxinsproductionanddistribution,e.g.bacterialfoodpoisoning.Thetoxinshavebeenproducedbeforeeating.Theperiodcanbeshorttoafewhours.Theperiodofrabiesdeterminestothelocationofvirusentry(wound).Ithasapositiverelationwiththedistance
6、ofthewoundtothecentralnervoussystem. 3)LatentinfectionWhenthemicroorganisminfectedthehostandlocalizedinsomeareaofthehost,itcanlatentlyforalongtimebecausethehostsimmunityisstrongenoughtolocatethepathogenbutcanwipesitout.Whenthehostsimmunitydecreased,overtinfectioncanoccurs.Suchlaten
7、tinfectioniscommoninsomediseases,e.g.herpessimplex,herpeszoster,malaria,tuberculosisetc.Generallythemicroorganismcannotbeexcretedduringlatentinfection,whichisadifferentpointfromcarrierstate.Notthateveryinfectiousdiseaseshaslatentinfection. 4)SourcesofinfectionThemicroorganismsareab
8、letogaintoaccesstotheperso
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