中药药剂学实验 suppositories.ppt

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1、ExperimentforPharmaceuticsofTCMChinaPharmaceuticalUniversityZhangJunyingDepartmentofPharmaceuticsofTCMChinaPharmaceuticalUniversityExercise6Suppositories——PreparationofShuanghuanglianSuppositoryChinaPharmaceuticalUniversityTCMsuppositoriesaresolidpreparationmadebyincorporatingextractsofcrud

2、edrugsorpowderedcrudedrugsinsuitablebases,intendedforintroductionintothecavities,suchasrectalandvaginal,ofthehumanbody.Itcanexertlocalorsystemiceffects.Whataresuppositories?IntroductionTypes:Lipidbase:suchascocoabutter,andsemi-syntheticfattyglycerides,etc..ChinaPharmaceuticalUniversityWater

3、solublebase:suchasamixtureofglycerinandgelatin,PEG,andpoloxamer,etc.IntroductionExtractumFlosLonicerae0.5gAPIExtractumScutellariae1.0gAPIExtractumForsythiae0.5gAPISemi-syntheticfattyglycerides7.8gBaseMakeupinto6suppositories【Formulation】ChinaPharmaceuticalUniversityBaseHeattomeltinawaterbat

4、h(80℃)ThedriedextractfinepowderMixwellScrape【Preparation】ChinaPharmaceuticalUniversityKeepthetemperatureat40℃MeltedbaseaddMixwellPourslowlyintomouldsCoolingandmodelingTakeoutSuppositories