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《基于静息态功能磁共振成像分析针刺治疗坐骨神经痛的脑功能网络.docx》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。
1、位时，其信号通过神经通路到达相应的脑功能区，使之被激活或者抑制，产生镇痛效应。这就为痛觉的共同脑功能网络及特异性的部位辨识区提供了初步证据，也为针刺镇痛的中枢作用机制提供了理论支持。关键词：静息态；脑功能磁共振成像；针刺镇痛；脑功能网络Studyonbrainfunctionalnetworkofacupuncturetreatmentonischioneuralgiabyrestingstate・fMRIYangyong(AcupunctureandMoxibustion&Massage)Directedbyzhouyo
2、ulongAbstractObjective:UsingthefunctionalMagneticResonanceImaging(fMRI)andthenetworkanalysistechniquestoinvestigatethebrainnetworkofpatientswithischioneuralgiaontime,andtoexplorethechangeofbrainfunctionnetwokofacupunctureanalgesia・Accordingtotheconsequence,therela
3、tionshipamongallthenucleusarcanalyzed.Inordertofindthenetworkofpainandacupunctureanalgesia,andtoelucidatethemechanismofcenteractionofischioneuralgia.restingstateMethods:1.10healthysubjectswerescannedbytherestingstatefunctionalMRIinthistrial.Thescanningprocessingin
4、volvesthestructureandtheresting-state(Rl).2.10patientswithischioneuralgiawerescannedtoo.Thescanningprocessinginvolvestheresting-state1(R1),theacupointstimulating(AP)andthercsting-statc2(R2).Imagesanddatasgainedintheworkstationwasanalyzedbythesesoftwares,suchasMRI2
5、.0,FSL,AFNIandsoon.Alldatawereanalyzedwiththeamplitudeoflowfrequencyfluctuations(ALFF).Thescanningprocedureasbelow:afterAP8min6s(R2)Result:1.Theactivatedregionsofrestingstate,comingfrom10healthysubjects,analyzedbyone-samplet-testduringR1wereoccipitallobeonbothside
6、,parietallobeonbothside,middlefrontalgyrus,superiorfrontalgyrus,frontalpoleonbothside.2.Theactivatedregionsofrestingstate,comingfrom10patientswithischioneuralgia,analyzedbyone-samplet-testduringR1wereparacentrallobule,ACC,thalamencephal,occipitallobe(allbothside);
7、theroundofthirdventricle,opticchiasma.PAG,vermisandsoon.3・Afteracupuncturethetheacupointsof"gentong2^ontheleftside,theactivatedregionsanalyzedbyone-samplet-testduringAPwereoccipitallobe,temporallobe,parietallobe,theleftsideofmesencephalic,cerebellum.4.Thepatientsa
8、ctivatedregionsanalyzedbyone-samplet-tcstofR2weretemporallobconbothsidc;thcleftsideofthalamcnccphal,splcniumofcorpuscallosum,opticchiasma,therightsideof
