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1、Job#:301542cDate:08-11-0712:31:17ToxicologyFourthEditionaboutthebook…Thisleadingtextbookinthefieldexaminesthemechanismsunderlyingtoxicity,Principlesofparticularlytheeventsatthemolecularlevelandthefactorsthatdetermineandaffecttoxicity.Theneweditionisupdatedtore
2、flectthelatestresearchinthebiochemicalbasisToxicologyBiochemicalPrinciplesoftoxicologyandthegrowingconcernsovertheadverseeffectsofdrugs,environmentalpollution,andoccupationalhazards.PrinciplesofBiochemicalToxicology,FourthEditionthoroughlyexplainsdose-response
3、relationships,dispositionandmetabolism,andtoxicresponsestoforeignBiochemicalcompounds,andpresentsdetailedexamplestomakethemechanismsoftoxicitymoreaccessibletostudentsencounteringthesubjectforthefirsttime.Comprehensiveinscopewithaclearandconciseapproach,thetext
4、includessummarysections,questionsandmodelanswers,andthoroughlyrevisedartworkthatservesasanessentialaidtolearningandteaching.ofNewtotheFourthEdition:Toxicology•reorganizedsectionsthatcoverbasicprinciplesfollowedbysectionsondifferenttypesoftoxicity•extensiveuseo
5、fexamplesthroughoutandnumerousexplanatorydiagrams•newmaterialonriskassessment,exportsystems,oxidativestress,Thalidomide,FourthEditionTamoxifen,peroxisomeproliferators,domoicacid,benzene,adriamycin,primaquine,biomarkers,cytochromeP450andotherenzymes,receptormed
6、iatedeffects,endocrinedisruption,botox,andmore•questionswithanswersforeachchapterforreviewandself-checking•expandedandupdatedchapterbibliographiesabouttheauthor...JOHNA.TIMBRELLisEmeritusProfessorofBiochemicalToxicology,King’sCollegeLondon,London,UK.Hereceived
7、hisPh.D.indrugmetabolismfromtheUniversityofLondon,London,UK.Dr.TimbrellisthefoundingeditorofthepublicationBiomarkersandhasservedontheeditorialboardofserveraljournals.Hismaintopicsofinterestincludetheroleoftaurineindetoxication/protection,toxicologyoftheliver,m
8、echanismsoftoxicityofcompoundsandbiomarkersofchemical-induceddysfunction.Dr.TimbrellistheauthorofIntroductiontoToxicology,ThirdEdition;andStudyToxicologyThroughQuestions.TimbrellPr
