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1、奥扎格雷钠联合疏血通治疗老年急性脑梗死的临床疗效分析［摘耍］目的探讨奥扎格雷钠联合疏血通治疗老年急性脑梗死的临床疗效。方法选取2014年3月〜2015年3月在我院治疗的老年脑樓死患者115例，所有患者随机分为观察组58例及对照组57例。对照组给予疏血通注射液静脉滴注。观察组在对照组基础上给予奥扎格雷钠治疗。观察两组患者的临床疗效，并对其神经功能缺损评分及不良反应发生情况进行观察。结果观察组患者的总有效率为94.83%,明显高于对照组的77.19%,两组比较差异有统计学意义（P〈0・05）。两组患者治疗后，神经功能缺损评
2、分与治疗前比较显著下降，差异有统计学意义（P〈0.05）。治疗后观察组患者的神经功能缺损评分显著低于对照组（卩〈0.05）。观察组患者的不良反应发生率为6.89%,明显低于对照组的17.24%,两组比较差异有统计学意义（卩〈0.05）。结论老年急性脑梗死采用奥扎格雷钠联合疏血通联合治疗，具有良好的临床疗效，可显著降低不良反应发生率及神经功能缺损评分，值得临床推广应用。［关键词］奥扎格雷钠；疏血通；老年急性脑梗死；临床疗效；神经功能缺损评分；不良反应［中图分类号］R743.3［文献标识码］B［文章编号］2095-0616
3、（2015）14-147-03AnalysisoftheclinicaleffectofsodiumozagrelcombinedwithShuxuetonginjectionintreatmentofacutecerebralinfarctionintheelderlyZHOUYongjunDepartmentofInternalMedicine,Linkou卩eople'sHospital,HeilongjiangProvince,Linkou157600,China[Abstract]ObjectiveToexp
4、loretheeffectofsodiumozagrelcombinedwithShuxuetonginjectionintreatmentofacutecerebralinfarctionintheelderly.Methods115casesofsenilecerebralinfarctiorbFromMarch2015toMarch2014inourhospitalwereal1collected,allpatientswererandomlydividedintoobservationgroup58casesa
5、ndcontrolgroupof57cases.ThecontrolgroupwasgivenShuxuetonginjectionintravenousdrip.Theobservationgroupinthecontrolgroupweregivensodiumozagrel.Toobservetheclinicaleffectoftwogroupsofpatients,neurologicalfunctiondefectscoreandadversereactionswereobserved・ResultsThe
6、totaleffectiverateoftheobservationgroupwas94.83%,significantlyhigherthanthatofthecontrolgroup,thedifferencebetweenthetwogroupswassignificant(P<0.05)・Theneurologicalfunctiondefectscoreintheobservationgroupwassignificantly1owerthanthatinthecontrolgroup,andthediffe
7、rencebetweenthetwogroupswassignificant(P<0.05)•Theincidenceofadversereactionsinobservationgroupwas6.89%,whichwassignifleantlylowerthanthatincontrolgroup(P<0.05),andthedifferencebetweenthetwogroupswassignificant(P<0.05).ConclusionInelderlypatientswithacutecerebra
8、linfarctionwithozagrelsodiumcombinedwithShuxuetongcombinedtreatment,ithasgoodclinicalcurativeeffect，cansignificantlyreduceadversereactionrateandneuralfunctiondefectsc
