软骨与骨组织.ppt

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1、Chapter4CartilageandBone1.Cartilage:organ=Cartilagetissue+perichondrium1)structureofcartilagetissue---cell:chondrocyte---cartilagematrix①chondrocyte:---Structure:LMembeddedincartilagelacunaperipheralcells:--smallandimmature--singleandflattenedcentralcell:--largeandmature,--roundandingroupof2-8c

2、ells-isogenousgroup--smallandroundnucleus--basophiliccytoplasm--EM:richinRERandGolgicomplexChondroblastsecretmatrixandfiberchondrocyteisogenousgroup:severalcellslocatesinonelacuna,whicharederivedfromasingle(same)parentcell②Cartilagematrix---groundsubstance:proteoglycan:--sametolooseCT--thereare

3、morechondroitinsulfatedistributedattheperipheryofcartilagelacuna---calledascartilagecapsule(basophilic)water---fiber:typeandnumberoffiberdependsonthetypeofcartilage2)Classification:accordingtothefiberHyalinecartilage:lesscollagenousfibrilarticularsurface,ribcartilage,tracheaandbronchiFibrouscar

4、tilage:largeamountofcollagenousfiberbundlescellsaresmallandlessintervertebraldisc,symphysispubisElasticcartilage:largeamountofelasticfiberexternalear,epiglottis3)perichondriumtwolayers:---outlayer:containmorefiber-protection---innerlayer:morecells-osteoprogenitorcell(fusiforminshape)4)growthofc

5、artilage---interstitialgrowth:innerchondrocyteproliferation→producefiberandmatrix.immaturecartilage---appositionalgrowth:osteoprogenitorcell→chondroblast→producefiberandmatrix→chondrocytegrowingandmaturecartilage2.Bone---consistsofbonetissue,periosteumandendosteum,bonemarrow1)Bonetissue①Cells:O

6、steoprogenitorcell↓osteoblast↓osteocyteosteoclasta.osteoprogenitorcell:stemcell---structure:fusiform,smallovoidnucleusslightbasophiliccytoplasmexistinperiosteumandendosteum---function:differentiatedintoosteoblastandchondrocyteb.osteoblast:---structure:LM:singlelayerofcuboidalorlowcolumnarcellro

7、undnucleusbasophiliccytoplasmlocatedonthesurfaceofbonetissueEM:fineprocessesrichinRER,Golgicomplex---function:ⅰ.synthesizebonecollagenfiberandgroundsubstance-osteoidⅱ.releasematrixvesicle:0.1umindiametermembrane-coatedALPase(Alkal