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1、花强l.Q.Hua,A.R・Joyce,B.0.PalssonandS.S・Fong.MetaboliccharacterizationofEscherichiacoliadaptedtogrowthonlactate,AppliedandEnvironmentalMicrobiology,73(14):4639-4647(2007).2.Q.Hua,A.R.Joyce,S.S.FongandB.0.Palsson.Metabolicanalysisofadaptiveevolutionforinsilicodesignedlactat
2、e-producingstrains,BiotechnologyandBioengineering,95(5):992-1002(2006).研究方向1•利用代谢物同位体信息开发代谢流量组和代谢组分析法2•微生物过程的代谢工程和系统生物学方法开发3.细胞代谢的模型化及优化代谢网络结构的设计4.生物燃料生产菌的代谢研究和代谢工程改造5•自适应进化过程中细胞代谢调控的作用鲍杰1•HongweiDong,JieBao*,DeweyD.YRyu,JianjiangZhong.2011.Designandconstructionofimprove
3、dnewvectorsforZymomonasmobiIisrecombinants.BiotechnologyandBioengineering108:1616-1627.2.Zhang,XiushengWang,DeqiangChu,YanqingHe,JieBao*.2011.Drypretreatmentoflignocellulosewithextremelylowsteamandwaterusageforbioethanolproduction.BioresourceTechnology102:4480-4488.3.Xia
4、oHuang,YumeiWang,WeiLiu,JieBao*.2011.BiologicalremovalofinhibitorsleadstotheimprovedlipidproductioninthelipidfermentationofcornstoverhydrolysatebyTrichosporoncutaneum・BioresourceTechnology}02:9705・9709.研究方向主要聚焦于以木质纤维索等生物质为原料,经过预处理和酶水解过程获得可发酵单糖,进而通过对能源微生物的代谢工程改造和先进的生物反应器与
5、发酵技术,获得液体生物燃料和关键生物基化学甜。主要研究方向包括:1.木质纤维素原料生物转化过程与产品的设计、合成、模拟、优化及其工业示范;2.木质纤维索依赖型能源微生物的发现、代谢工程改造与整合生物加工细胞构建彳诸*口1.XiangZou,Hai-fengHang,JuChu*,Ying-pingZhuang,Si-liangZhang,Oxygenuptakerateoptimizationwithnitrogenregulationforeiythromycinproductionandscale-upfrom50Lto372m3s
6、cale.BioresourceTechnology.2009,100:1406-14122.XiangZou,Hai-fcngHang,JuChu*,Ying-pingZhuang,Si-liangZhang、EnhancementoferythromycinAproductionwithfeedingavailablenitrogensourcesinerythromycinbiosynthesisphase,BioresourceTechnology,2009,100(13):3358-33653.XiangZou,Hai-fen
7、gHang,Chang-faChen,JuChu*,Ying-pingZhuang,Si-liangZhang,ApplicationofoxygenuptakerateandresponsesurfacemethodologyforerythromycinproductionbySaccharopolysporaerythraea.JIndMicrobiolBiotechnol200&35:1637-1642近年研究方向微牛•物代谢调控机制及发酵过程优化张嗣良1.ShuangxiChen,JuChu,YingpingZhuang,Si
8、liangZhang,EnhancementofinosineproductionbyBacillussubtilisthroughsuppressionofcarbonoverflowbysodiumci