新一代测序数据分析软件汇总

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1、新一代测序数据分析软件汇总IntegratedsolutionsCLCbioGenomicsWorkbench-denovoandreferenceassemblyofSanger,RocheFLX,Illumina,Helicos,andSOLiDdata・Commercialnext-gen-seqsoftwarethatextendstheCLCbioMainWorkbenchsoftware.IncludesSNPdetection,CHiP-seq,browserandotherfeatures・Commercia1.Windows,MacOSXandLinux・Galaxy-Ga

2、laxy=interactiveandreproduciblegenomics・Ajobwebporta1.Gcnomatix-IntegratedSolutionsforNextGenerationSequencingdataanalysis・JMPGenomics・NextgenvisualizationandstatisticstoolfromSAS.TheyarcworkingwithNCGRtorefinethistoolandproduceothers.NextGENe-denovoandreferenceassemblyofIllumina,SOLiDandRocheFLXda

3、ta.UsesanovelCondensationAssemblyToolapproachwherereadsarejoinedviaanchorsintomini-contigsbeforeassembly・IncludesSNPdetection,CHiP-seq,browserandotherfeatures・Commercial.WinorMacOS.SeqManGenomeAnalyser-SoftwareforNextGenerationsequenceassemblyofIllumina,RocheFLXandSangerdataintegratingwithLasergene

4、SequenceAnalysissoftwareforadditionalanalysisandvisualizationcapabilities・Canuseahybridtemplated/denovoapproach・Commercial.WinorMacOSX.SHORE・SHORE,forShortRead,isamappingandanalysispipelineforshortDNAsequencesproducedonaIlluminaGenomeAnalyzer・Asuitecreatedbythe1001Genomesproject.SourceforPOSIX・Slim

5、Search-Fledglingcommercialproduct・Align/AssembletoareferenceABySS-AssemblyByShortSequences.ABySSisadenovosequenceassemblerthatisdesignedforveryshortreads.Thesingle-processorversionisusefulforassemblinggenomesupto40-50Mbasesinsize・TheparallelversionisimplementedusingMPIandiscapableofassemblinglarger

6、genomes・BySimpsonJTandothersattheCanadasMichaelSmithGenomeSciencesCentre.C++assource.BFAST-Blat-likeFastAccurateSearchTool.WrittenbyNilsHomer,StanleyF.NelsonandBarryMerrimanatUCLA・Bowtie-Ultrafast,memory-efficientshortreadaligner・1(alignsshortDNAsequences(reads)tothehumangenomeatarateof25millionrea

7、dsperhouronatypicalworkstationwith2gigabytesofmemory.UsesaBurrows-Wheeler-Transformed(BWT)index.Linktodiscussionthreadhere.WrittenbyBenLangmeadandColeTrapnel1.Linux,Windows,andMacOSX.BWA-HengLeesBWTAlignmen