Davidson's Medicine 21st Ed Clinical bio and meta

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1、M.J.FieldL.BurnettD.R.SullivanP.StewartClinicalbiochemistryandmetabolism16Biochemicalinvestigations426Disordersofacid–basebalance441Disordersofaminoacidmetabolism447Functionalanatomyandphysiologyofacid–Integratedwaterandelectrolytebalance427Disordersofcarbohydratemetabolism447basehomeost

2、asis442Waterandelectrolytedistribution427Presentingproblemsindisordersofacid–baseDisordersofcomplexlipidmetabolism449Investigationofwaterandelectrolytes427balance442Disordersofbloodlipidsandlipoproteins449Disordersofsodiumbalance428Metabolicacidosis443Functionalanatomy,physiologyandFunct

3、ionalanatomyandphysiologyofrenalMetabolicalkalosis444investigationoflipidmetabolism449sodiumhandling428Respiratoryacidosis445Presentingproblemsindisordersoflipids451PresentingproblemsindisordersofsodiumRespiratoryalkalosis445balance430Mixedacid-basedisorders445Disordersofhaemmetabolism—t

4、heporphyrias456Sodiumdepletion430Disordersofdivalentionmetabolism446Sodiumexcess432FunctionalanatomyandphysiologyofDiuretictherapy433magnesiummetabolism446Disordersofwaterbalance434PresentingproblemsindisordersofFunctionalanatomyandphysiologyofrenalmagnesiummetabolism446waterhandling434H

5、ypomagnesaemia446PresentingproblemsindisordersofwaterHypermagnesaemia446balance435FunctionalanatomyandphysiologyofHyponatraemia435phosphatemetabolism446Hypernatraemia437PresentingproblemsindisordersofphosphateDisordersofpotassiumbalance438metabolism447Hypophosphataemia447Functionalanatom

6、yandphysiologyofrenalpotassiumhandling438Hyperphosphataemia447Presentingproblemsindisordersofpotassiumbalance438Hypokalaemia438Hyperkalaemia440425CliniCalbioChemistryandmetabolismThereisaworld-widetrendtowardsincreaseduseoflyticalcapacityandspeedoflaboratoryinstrumentation16laboratory-ba

7、seddiagnosticinvestigations,andbio-andthefollowingoperationaltrends:chemicalinvestigationsinparticular.Inhealth-care•Largecentralbiochemistrylaboratoriesfeaturesystemsofdevelopedcountries,ithasbeenestimatedextensiveuseofautomationandinformationthat60–70%ofallcriticaldecis