两种材质异体骨移植治疗创伤性骨缺损的临床效果

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1、两种材质异体骨移植治疗创伤性骨缺损的临床效果作者：孔志刚，于海泉单位：050051石家庄市，河北医科大学第三医院骨伤科【摘要】目的探讨大段异体骨复合自体骨和异体松质骨颗粒复合自体红骨髓移植治疗四肢创伤性骨缺损的方法及临床效果。方法自2002〜2006年，我们应用同种异体骨移植治疗创伤所性骨缺损及竹不愈合38例,根据忡缺损的部位及程度选择不同的方法，其中大段同种异体件复合自体忖治疗大段骨缺损16例，同种异体松质忖颗粒复合白体红忖髓移植治疗局限性骨缺损22例。结果获得10个月以上随访38例,37例骨性愈合。大段异体骨复合自体骨移植15例骨折愈合，愈合时间10〜25个月，

2、平均11.5个月，感染复发1例。局限性骨缺损松质骨颗粒复合自体骨髓移植22例骨折全部愈合。愈合时间3〜13个月，平均6个月。结论同种异体骨为-•种良好骨植入材料，长段异体件复合自体件片可用于创伤造成的人段骨缺损。异体松质骨颗粒复合自体红骨髓移植可用于修复陈旧性骨折骨不愈合和局限性骨缺损。【关键词】同种异体骨;自体骨;自体红骨攏；移植;骨折;骨缺损TheclinicalanalysisofrepairingtraumaticbonydefectwithgraftingmaterialsofdifferentallograftboneKONGZhigang,YUHaiq

3、uan.DepartmentofOrthopaedics,TheThirdHospitalofHebeiMedicalUniversity,Shijiazhuang050051【Abstract]ObjectiveToevaluatethemethodandtheclinicaloutcomeofrepairingtraumaticbonedefectofthelimbsbyusingbigallograftcombinedwithautograftboneandallogeneicCcincellousbonecombinedwithautologousredma

4、now.Methods38patientsoftraumaticbonydefectweretreatedwithallogeneicbonetninsplantationfromFebruary2002toApril2006.Differenttreatmentapproachsweretakenaccordingtothelocationsanddegreesofbonedefectinpatientswithtraumaticbonedefect・16casesweretreatedwithbigallograftcombinedwithautograftbo

5、ne,and22casesofpartialbonedefectweretreatedwithallogeneiccancellousbonecombinedwithautologousredmarrow.ResultsAllthepatientswerefollowedupformorethan10months,and37caseshadbonehealing・Thehealingperiodwas10〜25months(average11.5months)for15casestreatedwithbigallograftcombinedwithautograft

6、,and3〜13months(average6months)for22casesofpartialbonedefecttreatedwithallogeneiccancelluscombinedwithautologousredmairow.Onlyonecasewasfailedwithinfection.ConclusionAllograftboneisagoodmaterialsforboneimplantation,andlongallograftbonecombinedwithautologousbonecanbeusedtorepairlargebone

7、defects,whilecancelluscombinedwithautologousredmarrowcanbeusedtotreatoldfracturenothealingandrepairpartialbonedefect・[Keywords]allograftbone;autograftbone;autologousredmarrow;transplantation;fracture;bonedefect体骨移植是治疗骨缺损的常用方法，但体骨移植受体取骨量限制，且取佇可带来-些严重并发症。ft2002〜2006年，我们应用两种不同材质异体骨移植治疗创