光与组织的相互作用.ppt - 光与组织的相互作用

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1、TISSUEOPTICSGoodafternoon,students,todaywewilltalkaboutknowledgeoftissueOptics,andwillmainlyteachthatwhatistissueopticsandabsorptionintissue.光与组织的相互作用组织光学光的吸收、散射和透射生物组织的光学特性激光的生物学效应OutlineWhatisTissueOpticsAbsorptioninTissueAbsorptionProcessandParametersTypicalabsorbersinTissueWhatisTissu

2、eOptics?DefinitionsfromdictionaryOptics:asciencethatdealswithgenesisandpropagationoflightchangesthatitundergoesandproducesTissue:anaggregateofcellswhichusuallyofaparticularkindtogetherwiththeirintercellularsubstancethatformoneofthestructuralmaterialsofaplantorananimalthen,WhatisTissueOpti

3、cs?Tissueopticsiscombinationoftissueandoptics.Tissueismysubjectofinterestandopticsismyinvestigatingprinciple.TissueOpticsInvestigatingPrincipleSubjectofInterest+=TissueOpticsConstituentsofTissueOpticalPropertiesofTissuePropagationofLightInteractionbetweenLightandTissueDiagnosticandTherape

4、uticImplicationsWeareinterestedin…TissueOpticsOpticalSignalTissueLightSourceOpticalsignalwillbegainedafterlightthroughtissue.OpticalSignalfromTissueLargenumberofBiologicalMoleculesFunctionalandStructuralinformationNoninvasiveNearrealtimeOpticalsignalfromtissuecangainfunctionalandstructura

5、linformationoflargenumberofbiologicalmoleculeswithnoninvasiveandrealtime.ObjectivesofTissueOpticsKeyQuestion:Howmanyphotonspersecondwillreachthetissuechromophoreandbeabsorbed?Absorptionisimportantbecauseittransfersenergytotissue1.Tofindthelightenergyperunitareaperunittimethatreachesatarge

6、tchromophoreatsomeposition2.TodevelopmethodsbytheabsorptionandscatteringpropertiesoftissuecanbemeasuredUltimateGoalofTissueOpticswillbethatAssessallopticalpropertiesnoninvasiveinlivingtissue(invivo)WemustfaceDifficultiesthatTissueisacomplicatedheterogeneoussystemandRequiresnoninvasiveinvi

7、voinformationformeaningfuldiagnosticandtherapeuticpurposesABSORPTIONinTISSUEAbsorptionExtractionofenergyfromlightbyamolecularspeciesApplicationsofabsorptionintissueasfollowsDiagnosticapplications:Transitionsbetweentwoenergylevelsofamoleculethatarewelldefinedatspecif