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时间:2019-10-23
《胰岛素泵治疗1型糖尿病的临床分析》由会员上传分享,免费在线阅读,更多相关内容在工程资料-天天文库。
1、M(岛素泵治疗1型糖尿病的临床分析doi:10.3969/j.issn.1007-614x.2014.16.16摘要目的:探讨胰岛素泵治疗1型糖尿病的临床疗效。方法:2013年2月-2014年1月收治1型糖尿病患者100例,随机分为胰岛索泵持续皮下胰岛素输注(CSII)组和传统的多次皮下注射胰岛素法(MSII)组各50例。CSII组给予胰岛素泵持续皮下泵入短效优泌林,据血糖值调整用量。MSII组于三餐前皮下注射短效优泌林和睡前皮下注射中效优泌林。结果:两组患者治疗前空腹血糖、餐后2小时血糖比较差异无统计学意义(P>0.05),治疗后均明显下降,与治疗前比较差异有统
2、计学意义(P<0.05)oCSII组下降幅度明显优于MSII组,两组治疗后比较差异有统计学意义(P<0.05)oCSII组胰岛素用量26.9±8.0U/B,未发生低血糖反应,MSII组胰岛素用量34・6±6・5U/日,发生低血糖反应2例(4.0%),两组比较差异有统计学意义(P〈0・05)。结论:胰岛素泵治疗1型糖尿病,具有血糖控制效果好、胰岛索应用量少、发生低血糖率低等优点,值得临床推广。关键词胰岛素胰岛素泵1型糖尿病Clinicalanalysisofinsulinpumpintreatmentoftype1diabetesWangYanDepartmento
3、fEndocrinology,theCentralHospitalofHenanCokingCoalGroupEnergy,454000AbstractObjective:Toinvestigatetheclinicalefficacyofinsulinpumpintreatmentoftype1diabetes.Methods:100caseswithtype1diabeteswereselectedfromFebruary2013toJanuary2014.Theywererandomlydividedintothecontinuoussubcutaneous
4、insulininfusion(CS)groupandtheconventionalmultiplesubcutaneousinsulininjection(MSII)groupwith50casesineach.PatientsintheCSIIgroupworegivencontinuoussubcutancouspumpintotheshortactinghumulinusinginsulinpump,adjustedtheamountaccordingtobloodglucosevalue.PatientsintheMSIIweregivensubcuta
5、neousinjectionsofshortactinghumulinbeforemealsandinjectedhumulinnphbeforebedtime.Results:Thefastingglucoseand2hpostprandialbloodglucosebeforetreatmentintwogroupshadnostatisticallydifferenee(P>0.05).Thoseindexdecreasedaftertreatment,andtherewasstatisticallydifferencewhencomparedwiththo
6、seindexbeforetreatment(P<0.05).ThedecreasedoftheCSIIgroupwasmorepronouncedthanthatoftheMSIIgroup,andthedifferencewasstatisticallysignificantbetweenthetwogroupsaftertreatment(P<0.05).InsulindosageoftheCSIIwas(26・9±8)U/d,andtherewerenohypoglycemiareaction.InsulindosageoftheMSIIwas(34.6±
7、6.5)U/d,and2casesoccuredhypoglycemia(4%).Thedifferencewasstatisticallysignificantbetweenthetwogroups(P<0.05).Conclusion:Insulinpumpusedinthetreatmentoftype1diabetes,cancontrolbloodglucosebetter,uselessinsulin,and1owrateofhypoglycemia,soitisworthyofclinicalpromotion.KeywordsInsulin;Ins
8、ulinp
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