肝海绵状血管瘤英文·精品ppt课件

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1、肝脏海绵状血管瘤CavernousHemangiomaofLiverOutlinemostcommonbenign1%-20%indifferentplaceF〉M90%solitaryCavernousHemangiomaofLiverClinicalsymptomsMostofthemnevercausesymptomsorhealthproblems.andareincidentallydiscoveredatmedicalexamination,surgery,orautopsy(尸检).rightupperabdominalpain、pain,nausea(恶心)、enlarg

2、ementoftheliver；Largerhemangiomascanrupture,causingseverepainandbleedingintotheabdomenthatmaybesevereorevenshock.PathologicalappearanceCavernoushemangiomaisresultedfromendothelialcellsproliferation（增殖）.Thetumorconsistsinlarge(cavernous)spaces,linedbytumorendothelialcells，Theseinterconnectedspaces

3、arefilledwithbloodandseparatedbyafibroustissue。Oralcontraceptives（口服避孕药）andsteroids(类固醇)mayacceleratethegrowthofahemangioma.Whetherornotthesedrugsactuallyinducetheformationofthehemangiomaisunclear.CausesDiagnosis（CT）roundorsubround，smooth,lobulated,homogeneous,sometimesseptatedhypodensemassrelati

4、vetotheadjacentliverNonenhancedCTscans+C20’’动脉期contrast-enhancedCTscanarterialphaseThelesionappearsperipheralnodularenhancement（边缘结节状强化），thecenterofthelesiontypicallyremainshypodense.+C60’’门脉期portalvenousphasecontrastenhancementprogressescentripetally（向心性强化）untilfillsinthewholelesion.Theenhancedl

5、evelissimilartotheabdominalaorta.+C5’延迟期delayedphaseThewholelesionishomogeneousenhancement,thedensityishigherorequaltothesurroundingnormalliver(sometumorshavelow-densitycenterwhichrepresentfibreorthrombus).平扫+C20’’+C60’’+C5’快进慢出早出晚归Diagnosis（MRI）T1WIT1WIsmooth,lobulated,homogeneous,sometimessepta

6、tedhypointensemassrelativetotheliverNonenhancedMRIscansT2WImarkedlyhyperintensemass，thesignalintensityofthelesionissimilartothatofthecerebrospinalfluid.‘lightbulb’sign灯泡征T2WIcontrast-enhancedMRIscanTheseimagesdemonstratetheprogressive,centripetalcontrastenhancementinahemangioma.早出晚归快进慢出ohemangiom

7、ascandemonstrateimmediatehomogeneousenhancement(lesions<1.5cm)onodularcentripetalenhancementpatternprogressingtohomogeneity(lesions1.5-5cm)onodularcentripetalenhancementwithpersistentcentralhypointenseregion(lesions>5c