Metagenomics and industrial applications

Metagenomics and industrial applications

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1、PERSPECTIVES36.Casjens,S.Prophagesandbacterialgenomics:what45.Blaisdell,B.E.,Campbell,A.M.&Karlin,S.Similaritiesis,however,thatanyapplicationhastobehavewelearnedsofar?Mol.Microbiol.49,277–300anddissimilaritiesofphagegenomes.Proc.NatlAcad.(2003).Sci.USA93,5854–5859(1996).designedwithenzymaticconstr

2、aintsinmind,37.Lander,E.S.&Waterman,M.S.Genomicmappingbyleadingtosuboptimalprocessandreactionfingerprintingrandomclones:amathematicalanalysis.AcknowledgementsGenomics2,231–239(1988).SupportfromtheNationalScienceFoundationandMooreconditions.Insteadofdesigningaprocessto38.Angly,F.etal.PHACCS,anonlin

3、etoolforestimatingFoundationisgratefullyacknowledged.fitamediocreenzyme,itisconceivablethatthestructureanddiversityofunculturedviraltheuncultivatedmicrobialdiversity,togethercommunitiesusingmetagenomicinformation.BMCCompetinginterestsstatementBioinformatics6,41(2005).Theauthorsdeclarenocompetingfi

4、nancialinterests.withinvitroevolutiontechnologies,might39.Bak,P.HowNatureWorks:TheScienceofSelf-beusedtofindasuitablenaturalenzyme(s)OrganizedCriticality(Springer–Verlag,NewYork,1996).Onlinelinksthatcanserveasabackbonetoproducea40.Wommack,K.E.&Colwell,R.R.Virioplankton:virusesdesignerenzymethatopt

5、imallyfitsproc-inaquaticecosystems.Microbiol.Mol.Biol.Rev.64,DATABASES69–114.(2000).Thefollowingtermsinthisarticlearelinkedonlineto:essrequirementsthataresolelydictatedby41.Paul,J.,Jeffrey,W.&DeFlaun,M.DynamicsofEntrez:http://www.ncbi.nlm.nih.gov/Entrezsubstrateandproductproperties7.extracellularD

6、NAinthemarineenvironment.Appl.ΦX147

7、StreptococcuspyogenesstrainMGAS315

8、XylellaEnviron.Microbiol.53,170–179(1987).fastidiosastrainTemecula142.Paul,J.,Jiang,S.&Rose,J.ConcentrationofvirusesNovelty.ForindustriesthatproducebulkanddissolvedDNAfromaquaticenvironmentsbyFURTHERINFORMATIONvortexflowfiltrat

9、ion.Appl.Environ.Microbiol.57,ForestRohwer’slaboratory:http://phage.sdsu.educommoditiessuchashigh-performance2197–2204(1991).BLAST:http://www.ncbi.nlm.nih.gov/BLASTdetergents,asingleenzymebackbonewith43.Simon,M.&

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