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1、《海南医学》2001年第12卷第8期正常人心率变异性时域分析海南省人民医院心电图室(海口 570311) 王达开提要 目的:为了进一步探讨HRV时域的正常值及其与性别、年龄和心率因素的关系。方法 经24小时动态心电图监测117名健康正常人的心率变异性时域分析值;结果 显示:正常值范围:SDNN=141.7±29.2,SDNN指数=57.8±15.0。SDANN指数=130.9±28.3,RMSSD=39.0±15.0,PNN50=16.7±12.3,与国内外文献报道相近;男性SDNN指数高于女性的(P<0.05);HRV时域值与年龄(r=-0.269～-0.439,P<
2、0.01)和心率(r=-0.307～-0.476,P<0.001)呈负相关关系,即HVR随年龄和心率的增加而减少;其中<35岁和35岁～60岁年龄组的SDNN指数、RMSSD和PNN50指数呈极度显著性差异(P<0.001),≥60岁和35岁～60岁两年龄组的SDNN和SDNN指数值呈显著性差异(P<0.05),<60次P分和60～80次P分两心率组的SDNN、SDNN指数和SDANN指数值呈高度显著性差异(P<0.01),60～80次P分和≥80次P分两心率组的SDNN指数呈显著性差异(P<0.05)。结论:提示临床应用HRV时域值时须注意年龄、心率和性别因素。关键词
3、 正常值 心率变异性 时域分析AnalysisofTimeDomainofHeartRateVariability(HRV)amongHealthySubjectsWANGDakai,ElectrocardiogramDepartmentofthePeopleHospitalofHainanProvince,Haikou570311.AbstractObjective:InordertoapproachfurtherthecorrelationofthenormalvalueofHRVtimedomainwithsuchfactorsassex,ageandheartr
4、ate.Methods:ananalysisofHRVtimedoamainwasmadefrom117hralthysubjectsmonitoredby24-hourdy2namicelectrocardiogram.Results:Theresultsshowedthatthenormalvaluerangewas:SDNN=141.7±29.2,SDNNindex=57.8±15.0,SDANNindex=130.9±28.3,RMSSD=39.0±15.0,PNN50=16.7±12.3,whichissimilartothatreportedindomes2
5、ticandforeignliterature;thatSDNNindexfrommalehealthysubjectswashigherthanthatfromfemaleones(P<0.05)andHRVtimedomanivaluewasnegativelycorrelatedwithage(r=0.269-0.439,P<0.01)andheartrate(r=0.307-0.476,P<0.001),i.e.HRVdecreasedwithincreaseofageandheartrate;thatthereexistedamostsigificantdif
6、ferenceinSDNNindex,RMSSDandPNN50indexintwoagegroupsof<35yearsand35-60years(P<0.001)andasignificantdifferenceinSDNNandSDNNindexintwoagegroupsof≥60yearsand35-60years(P<0.05);andthatintwoheartrategroupsof<60pulsesPmin.and60-80pulsesPmin.existedahighlysignificantdifferenceinSDNN,SDNNindexand
7、SDANNindex(P<0.01)angintwoheartrategroupsof60-80pulsesPmin.and≥80pulsesPmin.asignificantdifferenceinSDNNindex(P<0.05).Conclusion:Thissuggeststhatsuchfactorsasage,heartrateandsexshouldbeconsideredwhenHRVtimedomainvalueisusedclinically.Keywords:NormalvalueHeaivratevariabili
