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1、CHINESEJOURNALOFANALYTICALCHEMISTRYVolume39,Issue4,April2011OnlineEnglisheditionoftheChineselanguagejournalCitethisarticleas:ChinJAnalChem,2011,39(4),592–598.REVIEWProgressinBoricacidBasedSaccharideSensors11122,DILing,WANGCang,WUJian,WANLin-Shu,XUZhi-Kang*1Departm
2、entofChemistry,ZhejiangUniversity,Hangzhou31002,China2MinstryofEducationKeyLaboratoryofMacromolecularSynthesisandFunctionalization,DepartmentofPolymerScienceandEngineering,ZhejiangUniversity,Hangzhou31002,ChinaAbstract:Becauseofthestronginteractionwithdiolmoieties
3、,boricacidplaysacriticalroleinthedesignofsaccharidesensors.Wepresentanoverviewaboutthedevelopmentofsaccharidesensorsbasedonvariousmechanisms,includingspectroscopies,pHindicators,andelectrochemistry.Thechemistryinvolvedinthebindingbetweenboricacidandsaccharidesisal
4、sodescribed.Furthermore,potentialdirectionsoffutureresearchfortheseboricacidbasedsaccharidesensorsarediscussed.KeyWords:Sacchariderecognition;Boricacid;Sensor;Review1Introductionrecognitionmoieties:(1)widedistributioninnature,therefore,thecostisrelativelyinexpensi
5、ve;(2)stableandcanbeSaccharidesareoneofthethreemajorclassesofoperatedunderharshcondition;(3)reversibleregenerationisbiomacromoleculesthatareessentialtolivingorganism,easilyachievedbyacidwash.Inthisregard,boricacidbasedwhichperformnumerousrolesinlivingsystems.Sacch
6、aridessaccharidesensorsshowgreatpromiseforvarioustherapeutic,arethemajorsourceoffuelformetabolismandareknowntodiagnostic,anddetectionapplicationsinfuture.Theaimofbeinvolvedinawiderangeofbiologicalandpathologicalthisreviewistopresentresearchprogressofthesesaccharid
7、eprocesses,includingcancermetastasis,celladhesion,cellsensorsfromdifferentaspects,suchasprincipalphysicsandsignaling,embryodevelopment,eggfertilization,proteinoperatingmechanismsofthesensors,aswellastheir[1–3]functionregulation,andcellularcommunications.applicatio
8、nsarediscussedindetail.Saccharidesensorsarerequiredeverywherefromthefoodandcosmeticindustriestomedicinalandacademicareas.2Mechanismsofboricacidbasedsacc
