Diagnostic Value of Computed Tomography in Chronic Obstructive Pulmonary Disease A Systematic Review and Meta-analysis（全文）

《Diagnostic Value of Computed Tomography in Chronic Obstructive Pulmonary Disease A Systematic Review and Meta-analysis（全文）》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、COPD,9:563–570,2012ISSN:1541-2555print/1541-2563onlineCopyright©InformaHealthcareUSA,Inc.DOI:10.3109/15412555.2012.692000ORIGINALRESEARCHDiagnosticValueofComputedTomographyinChronicObstructivePulmonaryDisease:ASystematicReviewandMeta-analysisJian-she

2、ngLi,1,2Hai-longZhang,1,3Yun-pingBai,1Yan-fangWang,1Hai-fengWang,2Ming-hangWang,2Su-yunLi,2andXue-qingYu21InstituteofGeriatrics,HenanUniversityofTraditionalChineseMedicine,Zhengzhou450008,AbstractChina2DepartmentofRespiratoryDiseases,theIntroduction:

3、Computedtomography(CT)hasbeenapprovedfordiagnosingFirstAffiliatedHospitalofHenanUniversityofTraditionalChineseMedicine,Zhengzhou450000,chronicobstructivepulmonarydisease(COPD).Thediagnosticaccuracy,however,Chinahasneverbeenexaminedinasystematicreview.

4、Therefore,weconductedameta-3DongzhimenHospitalAffiliatedtoBeijinganalysistoevaluatetheaccuracyofCTindiagnosingCOPD.Methods:ArticlesUniversityofChineseMedicine,Beijing100700,reportingdiagnosticaccuracyofCTforCOPDweresearchedfromsevenelectronicChinadata

5、basesandhandsearching.Tworeviewersindependentlyextracteddataandassessedmethodologicalquality.Sensitivity(SEN),specificity(SPE),positiveandnegativelikelihoodratios(LR+andLR–,respectively),anddiagnosticoddsratios(DOR)werepooledusingabivariatemodel.Thedi

6、agnosticperformanceofoveralltestalsowasassessedusingthevisualpoweroftheROCplottopresentthebivariatemodel.Potentialbetween-studyheterogeneitywasexploredusingsubgroupanalyses.Results:Datawereextractedfrom8studiesthatmettheForpersonaluseonly.inclusioncr

7、iteria.Allsummarymeasuresweregrosslyheterogeneousandthereforewouldnotbeappropriatelysummarized.Thesestudieswerefurtherstratifiedbytypeofimagingtechniqueandtestindex.ThesummaryestimatesofCTforCOPDwereasfollows:SEN,0.83(95%CI,0.73-0.89);SPE,0.87(95%CI,0

8、.70-0.95);LR+,6.2(95%CI,2.5-15.5);LR–,0.20(95%CI,0.12-0.34);andDOR,31(95%CI,8-116).ThefivesummaryestimatesofCTonthelungdensitywere0.80(95%CI,0.74-0.84),0.77(95%CI,0.58-0.89),3.5(95%CI,1.8-6.9),0.26(95%CI,0.20-0.34)and13(95%CI,6-32),respectively.Conclu