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1、OnemorereasontogetagoodsleepJeffIliffTEDMED0:11Sleep.It'ssomethingwespendaboutathirdofourlivesdoing,butdoanyofusreallyunderstandwhatit'sallabout?0:19Twothousandyearsago,Galen,oneofthemostprominentmedicalresearchersoftheancientworld,proposedthatwhilewe'reawake,ourbrain'smotiveforce,itsjuice
2、,wouldflowouttoalltheotherpartsofthebody,animatingthembutleavingthebrainalldriedup,andhethoughtthatwhenwesleep,allthismoisturethatfilledtherestofthebodywouldcomerushingback,rehydratingthebrainandrefreshingthemind.Now,thatsoundscompletelyridiculoustousnow,butGalenwassimplytryingtoexplainsom
3、ethingaboutsleepthatwealldealwitheveryday.See,weallknowbasedonourownexperiencethatwhenyousleep,itclearsyourmind,andwhenyoudon'tsleep,itleavesyourmindmurky.ButwhileweknowagreatdealmoreaboutsleepnowthanwhenGalenwasaround,westillhaven'tunderstoodwhyitisthatsleep,ofallofouractivities,hasthisin
4、crediblerestorativefunctionforthemind.1:17SotodayIwanttotellyouaboutsomerecentresearchthatmayshednewlightonthisquestion.We'vefoundthatsleepmayactuallybeakindofelegantdesignsolutiontosomeofthebrain'smostbasicneeds,auniquewaythatthebrainmeetsthehighdemandsandthenarrowmarginsthatsetitapartfro
5、malltheotherorgansofthebody.1:41Soalmostallthebiologythatweobservecanbethoughtofasaseriesofproblemsandtheircorrespondingsolutions,andthefirstproblemthateveryorganmustsolveisacontinuoussupplyofnutrientstofuelallthosecellsofthebody.Inthebrain,thatisespeciallycritical;itsintenseelectricalacti
6、vityusesupaquarterofthebody'sentireenergysupply,eventhoughthebrainaccountsforonlyabouttwopercentofthebody'smass.Sothecirculatorysystemsolvesthenutrientdeliveryproblembysendingbloodvesselstosupplynutrientsandoxygentoeverycornerofourbody.2:19Youcanactuallyseeitinthisvideohere.Here,we'reimagi
7、ngbloodvesselsinthebrainofalivingmouse.Thebloodvesselsformacomplexnetworkthatfillstheentirebrainvolume.Theystartatthesurfaceofthebrain,andthentheydivedownintothetissueitself,andastheyspreadout,theysupplynutrientsandoxygentoeachandeverycellinthebrain.2:44Now,ju
