资源描述：
《NCIC药物副反应分级》由会员上传分享，免费在线阅读，更多相关内容在行业资料-天天文库。
1、CTCVersion2.0PublishDate:April30,1999COMMONTOXICITYCRITERIA(CTC)GradeAdverseEvent01234ALLERGY/IMMUNOLOGYAllergicreaction/nonetransientrash,drugurticaria,drugfeversymptomaticanaphylaxishypersensitivityfever<38°C(<100.4°F)³38°C(³100.4°F),bronchospasm,(includingdrugfever)and/orasy
2、mptomaticrequiringparenteralbronchospasmmedication(s),withorwithouturticaria;allergy-relatededema/angioedemaNote:Isolatedurticaria,intheabsenceofothermanifestationsofanallergicorhypersensitivityreaction,isgradedintheDERMATOLOGY/SKINcategory.Allergicrhinitisnonemild,notrequiring
3、moderate,requiring--(includingsneezing,nasaltreatmenttreatmentstuffiness,postnasaldrip)Autoimmunereactionnoneserologicorotherevidenceofreversibleautoimmuneautoimmunereactionevidenceofautoimmunereactionreactioninvolvingcausingmajorgrade4autoimmunereactioninvolvinganon-functionof
4、amajororgandysfunction;butpatientisessentialorganororganorotheradverseprogressiveandasymptomatic(e.g.,function(e.g.,event(e.g.,transientirreversiblereaction;vitiligo),allorganhypothyroidism),colitisoranemia),long-termfunctionisnormalandrequiringtreatmentrequiringshort-termadmin
5、istrationofhigh-notreatmentisrequiredotherthanimmunosuppressivedoseimmuno-immunosuppressivetreatmentsuppressivetherapydrugsrequiredAlsoconsiderHypothyroidism,Colitis,Hemoglobin,Hemolysis.Serumsicknessnone--present-UrticariaisgradedintheDERMATOLOGY/SKINcategoryifitoccursasanisol
6、atedsymptom.Ifitoccurswithothermanifestationsofallergicorhypersensitivityreaction,gradeasAllergicreaction/hypersensitivityabove.Vasculitisnonemild,notrequiringsymptomatic,requiringrequiringsteroidsischemicchangesortreatmentmedicationrequiringamputationAllergy/Immunology-Otherno
7、nemildmoderateseverelife-threateningor(Specify,__________)disablingAUDITORY/HEARINGConductivehearinglossisgradedasMiddleear/hearingintheAUDITORY/HEARINGcategory.EaracheisgradedinthePAINcategory.Externalauditorycanalnormalexternalotitiswithexternalotitiswithexternalotitiswithnec
8、rosisofthecanalerythemaordrymoistdesquamationdischarge
