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1、PatientInformationResourcesfromASCOWhattoKnowASCO’sGuidelineonPreventingandTreatingBloodClotsOCTOBER2007KEYMESSAGES•Bloodclotsoccurfrequentlyinpeoplewithcancerforvariousreasons.•Bloodclotscanbepreventedinpeoplewithcancerandtreatedwithmedication.•Talkwithyourdoctoraboutyourriskfordeveloping
2、abloodclotandmeasuresyoucantaketopreventthem.ohelpdoctorsgivetheirpatientsthebestpossiblecare,theAmericanTSocietyofClinicalOncology(ASCO)asksitsmedicalexpertstodeveloprecommendationsforspecificareasofcancercare.ASCOdevelopedaclinicalpracticeguidelineaboutpreventingandtreatingbloodclotsforp
3、eoplewithcancer.ThisguideforpatientsisbasedonASCO’srecommendations.BACKGROUNDAbloodclot(alsocalledathrombus)isaserioussideeffectofcancerandcancertreatment.Itmaydevelopinanyvein(abloodvesselthatcarriesbloodtotheheart),butithappensmostofteninthelegs,thighs,orpelvis(lowerabdomen).Thisiscalled
4、deepveinthrombosis(DVT).Abloodclotthatbreaksawayfromtheplaceitformedandtravelsthroughtheveinstoadifferentsiteiscalledathromboembolism.Apulmonaryembolism(PE)isabloodclotinthelung,whichisapotentiallylife-threateningcondition.Bloodclotsoccurfrequentlyinpeoplewithcancerandarebecomingmorecommon
5、eachyearpossiblybecauseofnew,moreintensetreatmentsandcertainmedications.Theriskofdevelopingabloodclotisincreasedby:•Thecanceritself,especiallycancersofthelung,kidney,brain,gastrointestinal(digestive)system,femalereproductivesystem(suchasuterinecancer),andblood(suchasleukemiaandlymphoma)•Me
6、tastaticcancer(cancerthathasspreadtootherareasofthebodyfromtheoriginalorgan)•Cancertreatment,includingsurgery,chemotherapy,andhormonetherapy.Antiangiogenicdrugs(drugsthatblocktheformationofnewbloodvessels),suchasthalidomide(Synovir,Thalomid)and(Coumadin).Adoctormayuseanon-drugmethod,lenali
7、domide(Revlimid)mayalsoraisetheriskofcalledamechanicalmethod,inadditiontothedrugbloodclots.treatmentforthepreventionofbloodclots.Mechanicalmethodsincludegraduatedcompressionstockings•Treatmentwitherythropoiesisstimulatingagents(atypeofsupporthose);intermittent
